1993 …2020

Research output per year

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Research Output

2011

Activating and deactivating roles of lipid bilayers on the Ca 2+-ATPase/phospholamban complex

Gustavsson, M., Traaseth, N. J. & Veglia, G., Nov 29 2011, In : Biochemistry. 50, 47, p. 10367-10374 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes

Gaffarogullari, E. C., Masterson, L. R., Metcalfe, E. E., Traaseth, N. J., Balatri, E., Musa, M. M., Mullen, D., Distefano, M. D. & Veglia, G., Aug 26 2011, In : Journal of Molecular Biology. 411, 4, p. 823-836 14 p.

Research output: Contribution to journalArticle

30 Scopus citations

CAMP-dependent protein kinase A selects the excited state of the membrane substrate phospholamban

Masterson, L. R., Yu, T., Shi, L., Wang, Y., Gustavsson, M., Mueller, M. M. & Veglia, G., Sep 16 2011, In : Journal of Molecular Biology. 412, 2, p. 155-164 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy

Masterson, L. R., Shi, L., Metcalfe, E., Gao, J., Taylor, S. S. & Veglia, G., Apr 26 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 17, p. 6969-6974 6 p.

Research output: Contribution to journalArticle

106 Scopus citations

Erratum: Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology (Bioorganic and Medicinal Chemistry (2007)15 (931-938))

Mullen, D. G., Kyro, K., Hauser, M., Gustavsson, M., Veglia, G., Becker, J. M., Naider, F. & Distefano, M. D., May 1 2011, In : Bioorganic and Medicinal Chemistry. 19, 9, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Dynamics connect substrate recognition to catalysis in protein kinase A (Nature Chemical Biology (2010) 6 (821-828)

Masterson, L. R., Cheng, C., Yu, T., Tonelli, M., Kornev, A., Taylor, S. S. & Veglia, G., May 2011, In : Nature Chemical Biology. 7, 5, 1 p.

Research output: Contribution to journalComment/debate

12 Scopus citations

Lethal Arg9Cys phospholamban mutation hinders Ca2+-ATPase regulation and phosphorylation by protein kinase A

Ha, K. N., Mastersona, L. R., Hou, Z., Verardi, R., Walsh, N., Veglia, G. & Robia, S. L., Feb 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 7, p. 2735-2740 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Lipid-mediated folding/unfolding of phospholamban as a regulatory mechanism for the sarcoplasmic reticulum Ca2+-ATPase

Gustavsson, M., Traaseth, N. J., Karim, C. B., Lockamy, E. L., Thomas, D. D. & Veglia, G., May 13 2011, In : Journal of Molecular Biology. 408, 4, p. 755-765 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Multidimensional oriented solid-state NMR experiments enable the sequential assignment of uniformly 15N labeled integral membrane proteins in magnetically aligned lipid bilayers

Mote, K. R., Gopinath, T., Traaseth, N. J., Kitchen, J., Gor'Kov, P. L., Brey, W. W. & Veglia, G., Nov 1 2011, In : Journal of biomolecular NMR. 51, 3, p. 339-346 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Paramagnetic-based NMR restraints lift residual dipolar coupling degeneracy in multidomain detergent-solubilized membrane proteins

Shi, L., Traaseth, N. J., Verardi, R., Gustavsson, M., Gao, J. & Veglia, G., Feb 23 2011, In : Journal of the American Chemical Society. 133, 7, p. 2232-2241 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Probing membrane permeabilization by the antimicrobial peptide distinctin in mercury-supported biomimetic membranes

Becucci, L., Papini, M., Mullen, D., Scaloni, A., Veglia, G. & Guidelli, R., Nov 1 2011, In : Biochimica et Biophysica Acta - Biomembranes. 1808, 11, p. 2745-2752 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Probing membrane topology of the antimicrobial peptide distinctin by solid-state NMR spectroscopy in zwitterionic and charged lipid bilayers

Verardi, R., Traaseth, N. J., Shi, L., Porcelli, F., Monfregola, L., De Luca, S., Amodeo, P., Veglia, G. & Scaloni, A., Jan 1 2011, In : Biochimica et Biophysica Acta - Biomembranes. 1808, 1, p. 34-40 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
15 Scopus citations

Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method

Verardi, R., Shi, L., Traaseth, N. J., Walsh, N. & Veglia, G., May 31 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 22, p. 9101-9106 6 p.

Research output: Contribution to journalArticle

117 Scopus citations

Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology

Mullen, D. G., Kyro, K., Hauser, M., Gustavsson, M., Veglia, G., Becker, J. M., Naider, F. & Distefano, M. D., Jan 1 2011, In : Bioorganic and Medicinal Chemistry. 19, 1, p. 490-497 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Templating α-amylase peptide inhibitors with organotin compounds

Porcelli, F., Olivieri, C., Masterson, L. R., Wang, Y. & Veglia, G., Dec 1 2011, In : Journal of Biological Inorganic Chemistry. 16, 8, p. 1197-1204 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Topology and immersion depth of an integral membrane protein by paramagnetic rates from dissolved oxygen

Al-Abdul-Wahid, M. S., Verardi, R., Veglia, G. & Prosser, R. S., Sep 1 2011, In : Journal of Biomolecular NMR. 51, 1-2, p. 173-183 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2010

Dynamics connect substrate recognition to catalysis in protein kinase A

Masterson, L. R., Cheng, C., Yu, T., Tonelli, M., Kornev, A., Taylor, S. S. & Veglia, G., Nov 2010, In : Nature Chemical Biology. 6, 11, p. 821-828 8 p.

Research output: Contribution to journalArticle

145 Scopus citations

Improved resolution in dipolar NMR spectra using constant time evolution PISEMA experiment

Gopinath, T. & Veglia, G., Jul 9 2010, In : Chemical Physics Letters. 494, 1-3, p. 104-110 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
20 Scopus citations
32 Scopus citations

Probing slow protein dynamics by adiabatic R and R NMR experiments

Mangia, S., Traaseth, N. J., Veglia, G., Garwood, M. & Michaeli, S., Jul 28 2010, In : Journal of the American Chemical Society. 132, 29, p. 9979-9981 3 p.

Research output: Contribution to journalArticle

30 Scopus citations
20 Scopus citations

Sensitivity enhancement of separated local field experiments: Application to membrane proteins

Tata, G., Verardi, R., Traaseth, N. J. & Veglia, G., Apr 22 2010, In : Journal of Physical Chemistry B. 114, 15, p. 5089-5095 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Special issue on "Membrane Protein Dynamics: Correlating Structure to Function"

Veglia, G. & Ramamoorthy, A., Feb 1 2010, In : Biochimica et Biophysica Acta - Biomembranes. 1798, 2, p. 65-67 3 p.

Research output: Contribution to journalEditorial

2 Scopus citations

What can we learn from a small regulatory membrane protein?

Veglia, G., Ha, K. N., Shi, L., Verardi, R. & Traaseth, N. J., Nov 11 2010, In : Methods in molecular biology (Clifton, N.J.). 654, p. 303-319 17 p.

Research output: Contribution to journalArticle

8 Scopus citations
2009

A refinement protocol to determine structure, topology, and depth of insertion of membrane proteins using hybrid solution and solid-state NMR restraints

Shi, L., Traaseth, N. J., Verardi, R., Cembran, A., Gao, J. & Veglia, G., Jul 15 2009, In : Journal of biomolecular NMR. 44, 4, p. 195-205 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Backbone NMR resonance assignment of the catalytic subunit of cAMP-dependent protein kinase A in complex with AMP-PNP

Masterson, L. R., Shi, L., Tonelli, M., Mascioni, A., Mueller, M. M. & Veglia, G., Jun 1 2009, In : Biomolecular NMR Assignments. 3, 1, p. 115-117 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Expression and purification of isotopically labeled peptide inhibitors and substrates of cAMP-dependant protein kinase A for NMR analysis

Masterson, L. R., Bortone, N., Yu, T., Ha, K. N., Gaffarogullari, E. C., Nguyen, O. & Veglia, G., Apr 1 2009, In : Protein Expression and Purification. 64, 2, p. 231-236 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

One-sample approach to determine the relative orientations of proteins in ternary and binary complexes from residual dipolar coupling measurements

Tonelli, M., Masterson, L. R., Cornilescu, G., Markley, J. L. & Veglia, G., Oct 14 2009, In : Journal of the American Chemical Society. 131, 40, p. 14138-14139 2 p.

Research output: Contribution to journalArticle

12 Scopus citations

On the function of pentameric phospholamban: Ion channel or storage form?

Becucci, L., Cembran, A., Karim, C. B., Thomas, D. D., Guidelli, R., Gao, J. & Veglia, G., Jan 1 2009, In : Biophysical journal. 96, 10, p. L60-L62

Research output: Contribution to journalArticle

27 Scopus citations

Pseudoenzymatic dealkylation of alkyltins by biological dithiols

Porcelli, F., Triggiani, D., Buck-Koehntop, B. A., Masterson, L. R. & Veglia, G., Nov 1 2009, In : Journal of Biological Inorganic Chemistry. 14, 8, p. 1219-1225 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
36 Scopus citations

Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach

Traaseth, N. J., Shi, L., Verardi, R., Mullen, D. G., Barany, G. & Veglia, G., Jun 23 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 25, p. 10165-10170 6 p.

Research output: Contribution to journalArticle

133 Scopus citations

The role of sarcolipin and ATP in the transport of phosphate ion into the sarcoplasmic reticulum

Becucci, L., Guidelli, R., Karim, C. B., Thomas, D. D. & Veglia, G., Nov 15 2009, In : Biophysical journal. 97, 10, p. 2693-2699 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
28 Scopus citations
2008

Allosteric cooperativity in protein kinase A

Masterson, L. R., Mascioni, A., Traaseth, N. J., Taylor, S. S. & Veglia, G., Jan 15 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 2, p. 506-511 6 p.

Research output: Contribution to journalArticle

118 Scopus citations

Asymmetric methyl group labeling as a probe of membrane protein homo-oligomers by NMR spectroscopy

Traaseth, N. J., Verardi, R. & Veglia, G., Feb 27 2008, In : Journal of the American Chemical Society. 130, 8, p. 2400-2401 2 p.

Research output: Contribution to journalArticle

21 Scopus citations

Fluidic and air-stable supported lipid bilayer and cell-mimicking microarrays

Deng, Y., Wang, Y., Holtz, B., Li, J., Traaseth, N., Veglia, G., Stottrup, B. J., Elde, R., Pei, D., Guo, A. & Zhu, X. Y., May 14 2008, In : Journal of the American Chemical Society. 130, 19, p. 6267-6271 5 p.

Research output: Contribution to journalArticle

64 Scopus citations

NMR, mass spectrometry and chemical evidence reveal a different chemical structure for methanobactin that contains oxazolone rings

Behling, L. A., Hartsel, S. C., Lewis, D. E., DiSpirito, A. A., Choi, D. W., Masterson, L. R., Veglia, G. & Gallagher, W. H., Sep 24 2008, In : Journal of the American Chemical Society. 130, 38, p. 12604-12605 2 p.

Research output: Contribution to journalArticle

72 Scopus citations

NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles

Porcelli, F., Verardi, R., Shi, L., Henzler-Wildman, K. A., Ramamoorthy, A. & Veglia, G., May 20 2008, In : Biochemistry. 47, 20, p. 5565-5572 8 p.

Research output: Contribution to journalArticle

126 Scopus citations

Simultaneous detection and deconvolution of congested NMR spectra containing three isotopically labeled species

Masterson, L. R., Tonelli, M., Markley, J. L. & Veglia, G., Jun 25 2008, In : Journal of the American Chemical Society. 130, 25, p. 7818-7819 2 p.

Research output: Contribution to journalArticle

12 Scopus citations

Structural and dynamic basis of phospholamban and sarcolipin inhibition of Ca2+-ATPase

Traaseth, N. J., Ha, K. N., Verardi, R., Shi, L., Buffy, J. J., Masterson, L. R. & Veglia, G., Jan 8 2008, In : Biochemistry. 47, 1, p. 3-13 11 p.

Research output: Contribution to journalShort survey

99 Scopus citations

Structures of rat and human islet amyloid polypeptide IAPP1-19 in micelles by NMR spectroscopy

Nanga, R. P. R., Brender, J. R., Xu, J., Veglia, G. & Ramamoorthy, A., Dec 2 2008, In : Biochemistry. 47, 48, p. 12689-12697 9 p.

Research output: Contribution to journalArticle

139 Scopus citations
2007

An electrochemical investigation of sarcolipin reconstituted into a mercury-supported lipid bilayer

Becucci, L., Guidelli, R., Karim, C. B., Thomas, D. D. & Veglia, G., Oct 2007, In : Biophysical journal. 93, 8, p. 2678-2687 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Carbonyl carbon label selective (CCLS) 1H-15N HSQC experiment for improved detection of backbone 13 C-15N cross peaks in larger proteins

Tonelli, M., Masterson, L. R., Hallenga, K., Veglia, G. & Markley, J. L., Nov 1 2007, In : Journal of biomolecular NMR. 39, 3, p. 177-185 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Controlling the inhibition of the sarcoplasmic Ca2+-ATPase by tuning phospholamban structural dynamics

Ha, K. N., Traaseth, N. J., Verardi, R., Zamoon, J., Cembran, A., Karim, C. B., Thomas, D. D. & Veglia, G., Dec 21 2007, In : Journal of Biological Chemistry. 282, 51, p. 37205-37214 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Nonstereogenic α-aminoisobutyryl-glycyl dipeptidyl unit nucleates type I′ β-turn in linear peptides in aqueous solution

Masterson, L. R., Etienne, M. A., Porcelli, F., Barany, G., Hammer, R. P. & Veglia, G., Oct 16 2007, In : Biopolymers - Peptide Science Section. 88, 5, p. 746-753 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Proton-coupled electron transfer in a biomimetic peptide as a model of enzyme regulatory mechanisms

Sibert, R., Josowicz, M., Porcelli, F., Veglia, G., Range, K. & Barry, B. A., Apr 11 2007, In : Journal of the American Chemical Society. 129, 14, p. 4393-4400 8 p.

Research output: Contribution to journalArticle

51 Scopus citations