1993 …2020

Research output per year

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Research Output

2016

Orphan Spin Polarization: A Catalyst for High-Throughput Solid-State NMR Spectroscopy of Proteins

Gopinath, T. & Veglia, G., Jan 1 2016, Annual Reports on NMR Spectroscopy, 2016. Webb, G. A. (ed.). Academic Press Inc., p. 103-121 19 p. (Annual Reports on NMR Spectroscopy; vol. 89).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
7 Scopus citations

Probing Residue-Specific Water-Protein Interactions in Oriented Lipid Membranes via Solid-State NMR Spectroscopy

Dicke, A., Gopinath, T., Wang, Y. & Veglia, G., Oct 27 2016, In : Journal of Physical Chemistry B. 120, 42, p. 10959-10968 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
7 Scopus citations

Structural basis of synaptic vesicle assembly promoted by α-synuclein

Fusco, G., Pape, T., Stephens, A. D., Mahou, P., Costa, A. R., Kaminski, C. F., Kaminski Schierle, G. S., Vendruscolo, M., Veglia, G., Dobson, C. M. & De Simone, A., Sep 19 2016, In : Nature communications. 7, 12563.

Research output: Contribution to journalArticle

Open Access
75 Scopus citations

Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity

Fusco, G., De Simone, A., Arosio, P., Vendruscolo, M., Veglia, G. & Dobson, C. M., Jun 8 2016, In : Scientific reports. 6, 27125.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Tunable Liaisons: eEF-2K, CaM, and Calcium

Veglia, G. & Li, G., Sep 6 2016, In : Structure. 24, 9, p. 1438-1439 2 p.

Research output: Contribution to journalShort survey

Open Access

Uncoupling Catalytic and Binding Functions in the Cyclic AMP-Dependent Protein Kinase A

Kim, J., Li, G., Walters, M. A., Taylor, S. S. & Veglia, G., Mar 1 2016, In : Structure. 24, 3, p. 353-363 11 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2015

A tyrosine-tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette

Pagba, C. V., McCaslin, T. G., Veglia, G., Porcelli, F., Yohannan, J., Guo, Z., McDaniel, M. & Barry, B. A., Dec 1 2015, In : Nature communications. 6, 10010.

Research output: Contribution to journalArticle

16 Scopus citations

Dysfunctional conformational dynamics of protein kinase a induced by a lethal mutant of phospholamban hinder phosphorylation

Kim, J., Masterson, L. R., Cembran, A., Verardi, R., Shi, L., Gao, J., Taylor, S. S. & Veglia, G., Mar 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 12, p. 3716-3721 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Effects of naturally occurring arginine 14 deletion on phospholamban conformational dynamics and membrane interactions

Vostrikov, V. V., Soller, K. J., Ha, K. N., Gopinath, T. & Veglia, G., Jan 2015, In : Biochimica et Biophysica Acta - Biomembranes. 1848, 1, p. 315-322 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Formalin evokes calcium transients from the endoplasmatic reticulum

Fischer, M. J. M., Soller, K. J., Sauer, S. K., Kalucka, J., Veglia, G. & Reeh, P. W., Apr 15 2015, In : PloS one. 10, 4, e0123762.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic algorithm optimized triply compensated pulses in NMR spectroscopy

Manu, V. S. & Veglia, G., Nov 1 2015, In : Journal of Magnetic Resonance. 260, p. 136-143 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mapping the Hydrogen Bond Networks in the Catalytic Subunit of Protein Kinase A Using H/D Fractionation Factors

Li, G. C., Srivastava, A. K., Kim, J., Taylor, S. S. & Veglia, G., Jul 7 2015, In : Biochemistry. 54, 26, p. 4042-4049 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
13 Scopus citations

Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides

Soller, K. J., Verardi, R., Jing, M., Abrol, N., Yang, J., Walsh, N., Vostrikov, V. V., Robia, S. L., Bowser, M. T. & Veglia, G., Aug 21 2015, In : Scientific reports. 5, 13000.

Research output: Contribution to journalArticle

5 Scopus citations
22 Scopus citations

Structure and membrane interactions of chionodracine, a piscidin-like antimicrobial peptide from the icefish Chionodraco hamatus

Olivieri, C., Buonocore, F., Picchietti, S., Taddei, A. R., Bernini, C., Scapigliati, G., Dicke, A. A., Vostrikov, V. V., Veglia, G. & Porcelli, F., Jun 2015, In : Biochimica et Biophysica Acta - Biomembranes. 1848, 6, p. 1285-1293 9 p., 81836.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Development of a sensitive assay for SERCA activity using FRET detection of ADP

Jing, M., Verardi, R., Veglia, G. & Bowser, M. T., Mar 7 2014, In : Analytical Methods. 6, 5, p. 1468-1474 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour

Fusco, G., De Simone, A., Gopinath, T., Vostrikov, V., Vendruscolo, M., Dobson, C. M. & Veglia, G., May 29 2014, In : Nature communications. 5, 3827.

Research output: Contribution to journalArticle

156 Scopus citations

FLAMEnGO 2.0: An enhanced fuzzy logic algorithm for structure-based assignment of methyl group resonances

Chao, F. A., Kim, J., Xia, Y., Milligan, M., Rowe, N. & Veglia, G., Aug 2014, In : Journal of Magnetic Resonance. 245, p. 17-23 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
39 Scopus citations

Structural dynamics and conformational equilibria of serca regulatory proteins in membranes by solid-state NMR restrained simulations

De Simone, A., Mote, K. R. & Veglia, G., Jun 17 2014, In : Biophysical journal. 106, 12, p. 2566-2576 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling

Srivastava, A. K., McDonald, L. R., Cembran, A., Kim, J., Masterson, L. R., McClendon, C. L., Taylor, S. S. & Veglia, G., Dec 2 2014, In : Structure. 22, 12, p. 1735-1743 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanism

Cero, C., Vostrikov, V. V., Verardi, R., Severini, C., Gopinath, T., Braun, P. D., Sassano, M. F., Gurney, A., Roth, B. L., Vulchanova, L., Possenti, R., Veglia, G. & Bartolomucci, A., Dec 2 2014, In : Structure. 22, 12, p. 1744-1753 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
2013

Allosteric regulation of SERCA by phosphorylationmediated conformational shift of phospholamban

Gustavsson, M., Verardi, R., Mullen, D. G., Mote, K. R., Traaseth, N. J., Tata, G. & Veglia, G., Oct 22 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 43, p. 17338-17343 6 p.

Research output: Contribution to journalArticle

72 Scopus citations
26 Scopus citations

Modeling helical proteins using residual dipolar couplings, sparse long-range distance constraints and a simple residue-based force field

Eggimann, B. L., Vostrikov, V. V., Veglia, G. & Siepmann, J. I., Sep 3 2013, In : Theoretical Chemistry Accounts. 132, 10, p. 1-16 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

On the role of NMR spectroscopy for characterization of antimicrobial peptides

Porcelli, F., Ramamoorthy, A., Barany, G. & Veglia, G., Sep 20 2013, Membrane Proteins: Folding, Association, and Design. Ghirlanda, G. & Senes, A. (eds.). p. 159-180 22 p. (Methods in Molecular Biology; vol. 1063).

Research output: Chapter in Book/Report/Conference proceedingChapter

15 Scopus citations
24 Scopus citations

Protein dynamics: Catch them if you can

Veglia, G., Jul 2013, In : Nature Chemical Biology. 9, 7, p. 410-411 2 p.

Research output: Contribution to journalComment/debate

Role of conformational entropy in the activity and regulation of the catalytic subunit of protein kinase A

Veglia, G. & Cembran, A., Nov 1 2013, In : FEBS Journal. 280, 22, p. 5608-5615 8 p.

Research output: Contribution to journalReview article

18 Scopus citations
24 Scopus citations

Structural dynamics and topology of phosphorylated phospholamban homopentamer reveal its role in the regulation of calcium transport

Vostrikov, V. V., Mote, K. R., Verardi, R. & Veglia, G., Dec 3 2013, In : Structure. 21, 12, p. 2119-2130 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Structure and dynamics of a primordial catalytic fold generated by in vitro evolution

Chao, F. A., Morelli, A., Iii, J. C. H., Churchfield, L., Hagmann, L. N., Shi, L., Masterson, L. R., Sarangi, R., Veglia, G. & Seelig, B., Feb 1 2013, In : Nature Chemical Biology. 9, 2, p. 81-83 3 p.

Research output: Contribution to journalArticle

35 Scopus citations

Structures of the excited states of phospholamban and shifts in their populations upon phosphorylation

De Simone, A., Gustavsson, M., Montalvao, R. W., Shi, L., Veglia, G. & Vendruscolo, M., Sep 24 2013, In : Biochemistry. 52, 38, p. 6684-6694 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

VGF-Derived Peptide TLQP-21: Structure, Function, and Biomedical Implications

Cero, C., Verardi, R., Razzoli, M., Lodola, A., Possenti, R., Veglia, G. & Bartolomucci, A., Dec 1 2013, Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. Elsevier Inc., 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012
29 Scopus citations

Allostery and binding cooperativity of the catalytic subunit of protein kinase a by NMR spectroscopy and molecular dynamics simulations

Masterson, L. R., Cembran, A., Shi, L. & Veglia, G., 2012, Advances in Protein Chemistry and Structural Biology. Academic Press Inc., p. 363-389 27 p. (Advances in Protein Chemistry and Structural Biology; vol. 87).

Research output: Chapter in Book/Report/Conference proceedingChapter

27 Scopus citations

Antimicrobial properties of distinctin in an experimental model of MRSA-infected wounds

Simonetti, O., Cirioni, O., Ghiselli, R., Goteri, G., Orlando, F., Monfregola, L., De Luca, S., Zizzi, A., Silvestri, C., Veglia, G., Giacometti, A., Guerrieri, M., Offidani, A. & Scaloni, A., Nov 1 2012, In : European Journal of Clinical Microbiology and Infectious Diseases. 31, 11, p. 3047-3055 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase a by molecular dynamics simulations

Cembran, A., Masterson, L. R., McClendon, C. L., Taylor, S. S., Gao, J. & Veglia, G., Dec 21 2012, In : Biochemistry. 51, 51, p. 10186-10196 11 p.

Research output: Contribution to journalArticle

22 Scopus citations
54 Scopus citations

FLAMEnGO: A fuzzy logic approach for methyl group assignment using NOESY and paramagnetic relaxation enhancement data

Chao, F. A., Shi, L., Masterson, L. R. & Veglia, G., Jan 1 2012, In : Journal of Magnetic Resonance. 214, p. 103-110 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Heteronuclear adiabatic relaxation dispersion (hard) for quantitative analysis of conformational dynamics in proteins

Traaseth, N. J., Chao, F. A., Masterson, L. R., Mangia, S., Garwood, M., Michaeli, S., Seelig, B. & Veglia, G., Jun 1 2012, In : Journal of Magnetic Resonance. 219, p. 75-82 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Isotope labeling for solution and solid-state NMR spectroscopy of membrane proteins

Verardi, R., Traaseth, N. J., Masterson, L. R., Vostrikov, V. V. & Veglia, G., Dec 7 2012, Isotope labeling in Biomolecular NMR. Atreya, H. S. (ed.). p. 35-62 28 p. (Advances in Experimental Medicine and Biology; vol. 992).

Research output: Chapter in Book/Report/Conference proceedingChapter

45 Scopus citations

Phospholamban and its phosphorylated form require non-physiological transmembrane potentials to translocate ions

Becucci, L., Papini, M., Verardi, R., Veglia, G. & Guidelli, R., Apr 14 2012, In : Soft Matter. 8, 14, p. 3881-3888 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Probing ground and excited states of phospholamban in model and native lipid membranes by magic angle spinning NMR spectroscopy

Gustavsson, M., Traaseth, N. J. & Veglia, G., Feb 1 2012, In : Biochimica et Biophysica Acta - Biomembranes. 1818, 2, p. 146-153 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Synthesis and characterization of the 47-residue heterodimeric antimicrobial peptide distinctin, featuring directed disulfide bridge formation.

Mullen, D. G., Verardi, R., Porcelli, F., Scaloni, A., Barany, G. & Veglia, G., 2012, In : Biopolymers. 98, 5, p. 479-484 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

The hybrid solution/solid-state NMR method for membrane protein structure determination

Veglia, G., Traaseth, N. J., Shi, L., Verardi, R., Gopinath, T. & Gustavsson, M., Dec 1 2012, Comprehensive Biophysics. Elsevier Inc., Vol. 1. p. 182-198 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations
16 Scopus citations