1993 …2020

Research output per year

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Research Output

15N and 13C- SOFAST-HMQC editing enhances 3D-NOESY sensitivity in highly deuterated, selectively [1H,13C]-labeled proteins

Rossi, P., Xia, Y., Khanra, N., Veglia, G. & Kalodimos, C. G., Dec 1 2016, In : Journal of biomolecular NMR. 66, 4, p. 259-271 13 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

1H/15N heteronuclear NMR spectroscopy shows four dynamic domains for phospholamban reconstituted in dodecylphosphocholine micelles

Metcalfe, E. E., Zamoon, J., Thomas, D. D. & Veglia, G., Aug 2004, In : Biophysical journal. 87, 2, p. 1205-1214 10 p.

Research output: Contribution to journalArticle

66 Scopus citations
Open Access
7 Scopus citations

1H NMR Studies on the Interaction of β-Carboline Derivatives with Human Serum Albumin

Veglia, G., Delfini, M., Del Giudice, M. R., Gaggelli, E. & Valensin, G., Feb 1998, In : Journal of Magnetic Resonance. 130, 2, p. 281-286 6 p.

Research output: Contribution to journalArticle

24 Scopus citations
29 Scopus citations

Accurate Determination of Conformational Transitions in Oligomeric Membrane Proteins

Sanz-Hernández, M., Vostrikov, V. V., Veglia, G. & De Simone, A., Mar 15 2016, In : Scientific reports. 6, 23063.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Activating and deactivating roles of lipid bilayers on the Ca 2+-ATPase/phospholamban complex

Gustavsson, M., Traaseth, N. J. & Veglia, G., Nov 29 2011, In : Biochemistry. 50, 47, p. 10367-10374 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

A dynamic hydrophobic core orchestrates allostery in protein kinases

Kim, J., Ahuja, L. G., Chao, F. A., Xia, Y., McClendon, C. L., Kornev, A. P., Taylor, S. S. & Veglia, G., Apr 2017, In : Science Advances. 3, 4, e1600663.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

ALARM NMR for HTS triage and chemical probe validation

Dahlin, J. L., Cuellar, M., Singh, G., Nelson, K. M., Strasser, J., Rappe, T., Xia, Y., Veglia, G. & Walters, M. A., Mar 1 2018, In : Current protocols in chemical biology. 10, 1, p. 91-117 27 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Allosteric cooperativity in protein kinase A

Masterson, L. R., Mascioni, A., Traaseth, N. J., Taylor, S. S. & Veglia, G., Jan 15 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 2, p. 506-511 6 p.

Research output: Contribution to journalArticle

118 Scopus citations

Allosteric regulation of SERCA by phosphorylationmediated conformational shift of phospholamban

Gustavsson, M., Verardi, R., Mullen, D. G., Mote, K. R., Traaseth, N. J., Tata, G. & Veglia, G., Oct 22 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 43, p. 17338-17343 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Allosteric Regulation of the M2 Protein from Influenza A by Cholesterol

Veglia, G., Nelson, S. E. D. & Gopinath, T., Mar 29 2016, In : Biophysical journal. 110, 6, p. 1207-1208 2 p.

Research output: Contribution to journalShort survey

Open Access
1 Scopus citations

Allostery and binding cooperativity of the catalytic subunit of protein kinase a by NMR spectroscopy and molecular dynamics simulations

Masterson, L. R., Cembran, A., Shi, L. & Veglia, G., 2012, Advances in Protein Chemistry and Structural Biology. Academic Press Inc., p. 363-389 27 p. (Advances in Protein Chemistry and Structural Biology; vol. 87).

Research output: Chapter in Book/Report/Conference proceedingChapter

27 Scopus citations

A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes

Gaffarogullari, E. C., Masterson, L. R., Metcalfe, E. E., Traaseth, N. J., Balatri, E., Musa, M. M., Mullen, D., Distefano, M. D. & Veglia, G., Aug 26 2011, In : Journal of Molecular Biology. 411, 4, p. 823-836 14 p.

Research output: Contribution to journalArticle

30 Scopus citations

An electrochemical investigation of sarcolipin reconstituted into a mercury-supported lipid bilayer

Becucci, L., Guidelli, R., Karim, C. B., Thomas, D. D. & Veglia, G., Oct 2007, In : Biophysical journal. 93, 8, p. 2678-2687 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

An intramembrane sensory circuit monitors sortase A-mediated processing of streptococcal adhesins

Hall, J. W., Lima, B. P., Herbomel, G. G., Gopinath, T., McDonald, L. A., Shyne, M. T., Lee, J. K., Kreth, J., Ross, K. F., Veglia, G. & Herzberg, M. C., May 7 2019, In : Science signaling. 12, 580, eaas9941.

Research output: Contribution to journalArticle

1 Scopus citations

Antimicrobial properties of distinctin in an experimental model of MRSA-infected wounds

Simonetti, O., Cirioni, O., Ghiselli, R., Goteri, G., Orlando, F., Monfregola, L., De Luca, S., Zizzi, A., Silvestri, C., Veglia, G., Giacometti, A., Guerrieri, M., Offidani, A. & Scaloni, A., Nov 1 2012, In : European Journal of Clinical Microbiology and Infectious Diseases. 31, 11, p. 3047-3055 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
Open Access
10 Scopus citations

A refinement protocol to determine structure, topology, and depth of insertion of membrane proteins using hybrid solution and solid-state NMR restraints

Shi, L., Traaseth, N. J., Verardi, R., Cembran, A., Gao, J. & Veglia, G., Jul 15 2009, In : Journal of biomolecular NMR. 44, 4, p. 195-205 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

A Semiautomated Assignment Protocol for Methyl Group Side Chains in Large Proteins

Kim, J., Wang, Y., Li, G. & Veglia, G., Jan 1 2016, Methods in Enzymology. Academic Press Inc., p. 35-57 23 p. (Methods in Enzymology; vol. 566).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
1 Scopus citations

Asymmetric methyl group labeling as a probe of membrane protein homo-oligomers by NMR spectroscopy

Traaseth, N. J., Verardi, R. & Veglia, G., Feb 27 2008, In : Journal of the American Chemical Society. 130, 8, p. 2400-2401 2 p.

Research output: Contribution to journalArticle

21 Scopus citations

A synthetic peptide corresponding to the 550-585 region of α-dystroglycan binds β-dystroglycan as revealed by NMR spectroscopy

Bozzi, M., Veglia, G., Paci, M., Sciandra, F., Giardina, B. & Brancaccio, A., Jun 22 2001, In : FEBS Letters. 499, 3, p. 210-214 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

A tyrosine-tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette

Pagba, C. V., McCaslin, T. G., Veglia, G., Porcelli, F., Yohannan, J., Guo, Z., McDaniel, M. & Barry, B. A., Dec 1 2015, In : Nature communications. 6, 10010.

Research output: Contribution to journalArticle

16 Scopus citations

Backbone NMR resonance assignment of the catalytic subunit of cAMP-dependent protein kinase A in complex with AMP-PNP

Masterson, L. R., Shi, L., Tonelli, M., Mascioni, A., Mueller, M. M. & Veglia, G., Jun 1 2009, In : Biomolecular NMR Assignments. 3, 1, p. 115-117 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Biological chemistry of organotin compounds: Interactions and dealkylation by dithiols

Buck-Koehntop, B. A., Porcelli, F., Lewin, J. L., Cramer, C. J. & Veglia, G., Apr 1 2006, In : Journal of Organometallic Chemistry. 691, 8, p. 1748-1755 8 p.

Research output: Contribution to journalReview article

41 Scopus citations

Ca2+ ATPase Conformational Transitions in Lipid Bilayers Mapped by Site-directed Ethylation and Solid-State NMR

Vostrikov, V. V., Gustavsson, M., Tata, G., Mullen, D., Dicke, A. A., Truong, V. & Veglia, G., Feb 19 2016, In : ACS Chemical Biology. 11, 2, p. 329-334 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

CAMP-dependent protein kinase A selects the excited state of the membrane substrate phospholamban

Masterson, L. R., Yu, T., Shi, L., Wang, Y., Gustavsson, M., Mueller, M. M. & Veglia, G., Sep 16 2011, In : Journal of Molecular Biology. 412, 2, p. 155-164 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Carbonyl carbon label selective (CCLS) 1H-15N HSQC experiment for improved detection of backbone 13 C-15N cross peaks in larger proteins

Tonelli, M., Masterson, L. R., Hallenga, K., Veglia, G. & Markley, J. L., Nov 1 2007, In : Journal of biomolecular NMR. 39, 3, p. 177-185 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Clearance kinetics of the VGF-derived neuropeptide TLQP-21

Guo, Z. K., Sahu, B. S., He, R., Finan, B., Cero, C., Verardi, R., Razzoli, M., Veglia, G., Di Marchi, R. D., Miles, J. M. & Bartolomucci, A., Oct 2018, In : Neuropeptides. 71, p. 97-103 7 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase a by molecular dynamics simulations

Cembran, A., Masterson, L. R., McClendon, C. L., Taylor, S. S., Gao, J. & Veglia, G., Dec 21 2012, In : Biochemistry. 51, 51, p. 10186-10196 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Conformational Landscape of the PRKACA-DNAJB1 Chimeric Kinase, the Driver for Fibrolamellar Hepatocellular Carcinoma

Tomasini, M. D., Wang, Y., Karamafrooz, A., Li, G., Beuming, T., Gao, J., Taylor, S. S., Veglia, G. & Simon, S. M., Dec 1 2018, In : Scientific reports. 8, 1, 720.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Conformational preferences of the amylin nucleation site in SDS micelles: An NMR study

Mascioni, A., Porcelli, F., Ilangovan, U., Ramamoorthy, A. & Veglia, G., May 1 2003, In : Biopolymers. 69, 1, p. 29-41 13 p.

Research output: Contribution to journalArticle

49 Scopus citations

Conformational study of [Met5]enkephalin-Arg-Phe in the presence of phosphatidylserine vesicles

D'Alagni, M., Delfini, M., Di Nola, A., Eisenberg, M., Paci, M., Roda, L. G. & Veglia, G., Jan 1 1996, In : European Journal of Biochemistry. 240, 3, p. 540-549 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Controlling the inhibition of the sarcoplasmic Ca2+-ATPase by tuning phospholamban structural dynamics

Ha, K. N., Traaseth, N. J., Verardi, R., Zamoon, J., Cembran, A., Karim, C. B., Thomas, D. D. & Veglia, G., Dec 21 2007, In : Journal of Biological Chemistry. 282, 51, p. 37205-37214 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein

Fusco, G., Pape, T., Stephens, A. D., Mahou, P., Costa, A. R., Kaminski, C. F., Schierle, G. S. K., Vendruscolo, M., Veglia, G., Dobson, C. M. & De Simone, A., May 11 2017, In : Nature communications. 8, 1 p.

Research output: Contribution to journalArticle

Open Access

Cushing’s syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity

Walker, C., Wang, Y., Olivieri, C., Karamafrooz, A., Casby, J., Bathon, K., Calebiro, D., Gao, J., Bernlohr, D. A., Taylor, S. S. & Veglia, G., Aug 28 2019, In : Science advances. 5, 8, eaaw9298.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Cysteine-ethylation of tissue-extracted membrane proteins as a tool to detect conformational states by solid-state NMR spectroscopy

Weber, D. K., Bader, T., Larsen, E. K., Wang, S., Gopinath, T., Distefano, M. & Veglia, G., 2019, Methods in Enzymology. Shukla, A. K. (ed.). Academic Press Inc., p. 281-304 24 p. (Methods in Enzymology; vol. 621).

Research output: Chapter in Book/Report/Conference proceedingChapter

Dealkylation of Organotin Compounds by Biological Dithiols: Toward the Chemistry of Organotin Toxicity

Buck, B., Mascioni, A., Que, L. & Veglia, G., Nov 5 2003, In : Journal of the American Chemical Society. 125, 44, p. 13316-13317 2 p.

Research output: Contribution to journalArticle

44 Scopus citations

Defining the Intramembrane Binding Mechanism of Sarcolipin to Calcium ATPase Using Solution NMR Spectroscopy

Buffy, J. J., Buck-Koehntop, B. A., Porcelli, F., Traaseth, N. J., Thomas, D. D. & Veglia, G., Apr 28 2006, In : Journal of Molecular Biology. 358, 2, p. 420-429 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Design and characterization of chionodracine-derived antimicrobial peptides with enhanced activity against drug-resistant human pathogens

Olivieri, C., Bugli, F., Menchinelli, G., Veglia, G., Buonocore, F., Scapigliati, G., Stocchi, V., Ceccacci, F., Papi, M., Sanguinetti, M. & Porcelli, F., Jan 1 2018, In : RSC Advances. 8, 72, p. 41331-41346 16 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Determination of helical membrane protein topology using residual dipolar couplings and exhaustive search algorithm: Application to phospholamban

Mascioni, A., Eggimann, B. L. & Veglia, G., Oct 1 2004, In : Chemistry and Physics of Lipids. 132, 1, p. 133-144 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
26 Scopus citations

Deuterium/hydrogen exchange factors measured by solution nuclear magnetic resonance spectroscopy as indicators of the structure and topology of membrane proteins

Veglia, G., Zeri, A. C., Ma, C. & Opella, S. J., Jan 1 2002, In : Biophysical journal. 82, 4, p. 2176-2183 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Development of a sensitive assay for SERCA activity using FRET detection of ADP

Jing, M., Verardi, R., Veglia, G. & Bowser, M. T., Mar 7 2014, In : Analytical Methods. 6, 5, p. 1468-1474 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dipolar waves as NMR maps of protein structure

Mesleh, M. F., Veglia, G., DeSilva, T. M., Marassi, F. M. & Opella, S. J., Apr 24 2002, In : Journal of the American Chemical Society. 124, 16, p. 4206-4207 2 p.

Research output: Contribution to journalArticle

92 Scopus citations

Dipolar waves map the structure and topology of helices in membrane proteins

Mesleh, M. F., Lee, S., Veglia, G., Thiriot, D. S., Marassi, F. M. & Opella, S. J., Jul 23 2003, In : Journal of the American Chemical Society. 125, 29, p. 8928-8935 8 p.

Research output: Contribution to journalArticle

87 Scopus citations

Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour

Fusco, G., De Simone, A., Gopinath, T., Vostrikov, V., Vendruscolo, M., Dobson, C. M. & Veglia, G., May 29 2014, In : Nature communications. 5, 3827.

Research output: Contribution to journalArticle

156 Scopus citations
54 Scopus citations