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Research Output 2004 2020

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Article
2020

Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations

Pampusch, M. S., Haran, K. P., Hart, G. T., Rakasz, E. G., Rendahl, A. K., Berger, E. A., Connick, E. & Skinner, P. J., Mar 13 2020, In : Molecular Therapy - Methods and Clinical Development. 16, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
Maintenance
T-Cell Antigen Receptor
Macaca mulatta
T-Lymphocytes
Population
2019
9 Citations (Scopus)

Adaptive NK cells in people exposed to Plasmodium falciparum correlate with protection from malaria

Hart, G. T., Tran, T. M., Theorell, J., Schlums, H., Arora, G., Rajagopalan, S., Sangala, A. D. J., Welsh, K. J., Traore, B., Pierce, S. K., Crompton, P. D., Bryceson, Y. T. & Long, E. O., Jun 3 2019, In : The Journal of experimental medicine. 216, 6, p. 1280-1290 11 p.

Research output: Contribution to journalArticle

Open Access
Plasmodium falciparum
Natural Killer Cells
Malaria
Antibodies
Mali
4 Citations (Scopus)

A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation

Tran, T. M., Guha, R., Portugal, S., Skinner, J., Ongoiba, A., Bhardwaj, J., Jones, M., Moebius, J., Venepally, P., Doumbo, S., DeRiso, E. A., Li, S., Vijayan, K., Anzick, S. L., Hart, G. T., O'Connell, E. M., Doumbo, O. K., Kaushansky, A., Alter, G., Felgner, P. L. & 5 others, Lorenzi, H., Kayentao, K., Traore, B., Kirkness, E. F. & Crompton, P. D., Oct 15 2019, In : Immunity. 51, 4, p. 750-765.e10

Research output: Contribution to journalArticle

Malaria
Fever
Inflammation
Parasitemia
Longitudinal Studies
2018
10 Citations (Scopus)

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells

Burrack, K. S., Huggins, M. A., Taras, E., Dougherty, P., Henzler, C. M., Yang, R., Alter, S., Jeng, E. K., Wong, H. C., Felices, M., Cichocki, F., Miller, J. S., Hart, G. T., Johnson, A. J., Jameson, S. C. & Hamilton, S. E., Apr 17 2018, In : Immunity. 48, 4, p. 760-772.e4

Research output: Contribution to journalArticle

Open Access
Cerebral Malaria
Interleukin-15
Natural Killer Cells
Interleukin-10
Blood-Brain Barrier
16 Citations (Scopus)

NK cells inhibit plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity

Arora, G., Hart, G. T., Manzella-Lapeira, J., Doritchamou, J. Y. A., Narum, D. L., Thomas, L. M., Brzostowski, J., Rajagopalan, S., Doumbo, O. K., Traore, B., Miller, L. H., Pierce, S. K., Duffy, P. E., Crompton, P. D., Desai, S. A. & Long, E. O., Jun 26 2018, In : eLife. 7, e36806.

Research output: Contribution to journalArticle

Open Access
Plasmodium falciparum
Cytotoxicity
Natural Killer Cells
Blood
Erythrocytes
2016
40 Citations (Scopus)

CD8+T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

Swanson, P. A., Hart, G. T., Russo, M. V., Nayak, D., Yazew, T., Peña, M., Khan, S. M., Janse, C. J., Pierce, S. K. & McGavern, D. B., Dec 1 2016, In : PLoS pathogens. 12, 12, e1006022.

Research output: Contribution to journalArticle

Cerebral Malaria
Brain Stem
Pathology
T-Lymphocytes
Antigens
4 Citations (Scopus)

The regulation of inherently autoreactive VH4-34-expressing B cells in individuals living in a malaria-endemic area of West Africa

Hart, G. T., Akkaya, M., Chida, A. S., Wei, C., Jenks, S. A., Tipton, C., He, C., Wendel, B. S., Skinner, J., Arora, G., Kayentao, K., Ongoiba, A., Doumbo, O., Traore, B., Narum, D. L., Jiang, N., Crompton, P. D., Sanz, I. & Pierce, S. K., Nov 15 2016, In : Journal of Immunology. 197, 10, p. 3841-3849 9 p.

Research output: Contribution to journalArticle

Western Africa
Malaria
B-Lymphocytes
Immunoglobulin G
Falciparum Malaria
2015
21 Citations (Scopus)

Inhibiting the mammalian target of rapamycin blocks the development of experimental cerebral malaria

Gordon, E. B., Hart, G. T., Tran, T. M., Waisberg, M., Akkaya, M., Skinner, J., Zinöcker, S., Pena, M., Yazew, T., Qi, C. F., Miller, L. H. & Pierce, S. K., Jun 2 2015, In : mBio. 6, 3

Research output: Contribution to journalArticle

Cerebral Malaria
Sirolimus
Malaria
Parasites
Brain
38 Citations (Scopus)

Targeting glutamine metabolism rescues mice from late-stage cerebral malaria

Gordon, E. B., Hart, G. T., Tran, T. M., Waisberg, M., Akkaya, M., Kim, A. S., Hamilton, S. E., Pena, M., Yazew, T., Qi, C. F., Lee, C. F., Lo, Y. C., Miller, L. H., Powell, J. D. & Pierce, S. K., Oct 20 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 42, p. 13075-13080 6 p.

Research output: Contribution to journalArticle

Cerebral Malaria
Diazooxonorleucine
Glutamine
Brain Edema
Blood-Brain Barrier
2012
4 Citations (Scopus)

Cutting edge: Krüppel-like factor 2 is required for phenotypic maintenance but not development of B1 B cells

Hart, G. T., Peery, S. L., Hamilton, S. E. & Jameson, S. C., Oct 1 2012, In : Journal of Immunology. 189, 7, p. 3293-3297 5 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Maintenance
Cell Survival
Knockout Mice
Cell Count
2011
48 Citations (Scopus)
B-Lymphocyte Subsets
B-Lymphocytes
Lysosphingolipid Receptors
T-Lymphocytes
Integrins
32 Citations (Scopus)

Kruppel-like factor 2 is required for trafficking but not quiescence in postactivated T cells

Takada, K., Wang, X., Hart, G. T., Odumade, O. A., Weinreich, M. A., Hogquist, K. A. & Jameson, S. C., Jan 15 2011, In : Journal of Immunology. 186, 2, p. 775-783 9 p.

Research output: Contribution to journalArticle

Kruppel-Like Transcription Factors
T-Lymphocytes
Cytokines
Cell Differentiation
Cell Cycle
2004
24 Citations (Scopus)

Quantitative gene expression profiling implicates genes for susceptibility and resistance to alveolar bone loss

Hart, G. T., Shaffer, D. J., Akilesh, S., Brown, A. C., Moran, L., Roopenian, D. C. & Baker, P. J., Aug 1 2004, In : Infection and immunity. 72, 8, p. 4471-4479 9 p.

Research output: Contribution to journalArticle

Alveolar Bone Loss
Gene Expression Profiling
Gingiva
Genes
Interleukin-1beta
54 Citations (Scopus)

Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development

Bouma, G. J., Hart, G. T., Washburn, L. L., Recknagel, A. K. & Eicher, E. M., Nov 1 2004, In : Gene Expression Patterns. 5, 1, p. 141-149 9 p.

Research output: Contribution to journalArticle

Gonads
Fetal Development
Real-Time Polymerase Chain Reaction
Gene Expression
Genes