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Geoffrey T Hart

20042024
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  • 4 Similar Profiles
Cerebral Malaria Medicine & Life Sciences
Malaria Medicine & Life Sciences
Natural Killer Cells Medicine & Life Sciences
Plasmodium falciparum Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Interleukin-15 Medicine & Life Sciences
Parasites Medicine & Life Sciences

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Projects 2019 2024

Regulation of the Immune Response to Plasmodium by IL-10 Producing Natural Killer Cells

Hamilton Hart, S. E. & Hart, G. T.

NIH Nat'l Inst of Allergy & Infect Dis

2/8/19 → 1/31/24

Project: Research project

natural killer cells
Plasmodium
interleukin-10
immune response

Research Output 2004 2019

3 Citations (Scopus)

Adaptive NK cells in people exposed to Plasmodium falciparum correlate with protection from malaria

Hart, G. T., Tran, T. M., Theorell, J., Schlums, H., Arora, G., Rajagopalan, S., Sangala, A. D. J., Welsh, K. J., Traore, B., Pierce, S. K., Crompton, P. D., Bryceson, Y. T. & Long, E. O., Jun 3 2019, In : The Journal of experimental medicine. 216, 6, p. 1280-1290 11 p.

Research output: Contribution to journal › Article

Open Access
Plasmodium falciparum
Natural Killer Cells
Malaria
Antibodies
Mali
2 Citations (Scopus)

A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation

Tran, T. M., Guha, R., Portugal, S., Skinner, J., Ongoiba, A., Bhardwaj, J., Jones, M., Moebius, J., Venepally, P., Doumbo, S., DeRiso, E. A., Li, S., Vijayan, K., Anzick, S. L., Hart, G. T., O'Connell, E. M., Doumbo, O. K., Kaushansky, A., Alter, G., Felgner, P. L. & 5 others, Lorenzi, H., Kayentao, K., Traore, B., Kirkness, E. F. & Crompton, P. D., Oct 15 2019, In : Immunity. 51, 4, p. 750-765.e10

Research output: Contribution to journal › Article

Malaria
Fever
Inflammation
Parasitemia
Longitudinal Studies
9 Citations (Scopus)

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells

Burrack, K. S., Huggins, M. A., Taras, E., Dougherty, P., Henzler, C. M., Yang, R., Alter, S., Jeng, E. K., Wong, H. C., Felices, M., Cichocki, F., Miller, J. S., Hart, G. T., Johnson, A. J., Jameson, S. C. & Hamilton, S. E., Apr 17 2018, In : Immunity. 48, 4, p. 760-772.e4

Research output: Contribution to journal › Article

Open Access
Cerebral Malaria
Interleukin-15
Natural Killer Cells
Interleukin-10
Blood-Brain Barrier
11 Citations (Scopus)

NK cells inhibit plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity

Arora, G., Hart, G. T., Manzella-Lapeira, J., Doritchamou, J. Y. A., Narum, D. L., Thomas, L. M., Brzostowski, J., Rajagopalan, S., Doumbo, O. K., Traore, B., Miller, L. H., Pierce, S. K., Duffy, P. E., Crompton, P. D., Desai, S. A. & Long, E. O., Jun 26 2018, In : eLife. 7, e36806.

Research output: Contribution to journal › Article

Open Access
Plasmodium falciparum
Cytotoxicity
Natural Killer Cells
Blood
Erythrocytes
32 Citations (Scopus)

CD8+T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

Swanson, P. A., Hart, G. T., Russo, M. V., Nayak, D., Yazew, T., Peña, M., Khan, S. M., Janse, C. J., Pierce, S. K. & McGavern, D. B., Dec 1 2016, In : PLoS pathogens. 12, 12, e1006022.

Research output: Contribution to journal › Article

Cerebral Malaria
Brain Stem
Pathology
T-Lymphocytes
Antigens