Research output per year
Research output per year
Research output
- 16 Article
- 16 results
Search results
-
2023
Sickle red blood cell-derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor
An, R., Man, Y., Cheng, K., Zhang, T., Chen, C., Wang, F., Abdulla, F., Kucukal, E., Wulftange, W. J., Goreke, U., Bode, A., Nayak, L. V., Vercellotti, G. M., Belcher, J. D., Little, J. A. & Gurkan, U. A., May 2023, In: British journal of haematology. 201, 3, p. 552-563 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease
Belcher, J. D., Nataraja, S., Abdulla, F., Zhang, P., Chen, C., Nguyen, J., Ruan, C., Singh, M., Demes, S., Olson, L., Stickens, D., Stanwix, J., Clarke, E., Huang, Y., Biddle, M. & Vercellotti, G. M., 2023, In: Frontiers in Medicine. 10, 1101501.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease
Belcher, J. D., Nguyen, J., Chen, C., Abdulla, F. R., Conglin, R., Ivy, Z. K., Cummings, J., Dudler, T. & Vercellotti, G. M., Nov 2022, In: Translational Research. 249, p. 1-12 12 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence
Gentinetta, T., Belcher, J. D., Brügger-Verdon, V., Adam, J., Ruthsatz, T., Bain, J., Schu, D., Ventrici, L., Edler, M., Lioe, H., Patel, K., Chen, C., Nguyen, J., Abdulla, F., Zhang, P., Wassmer, A., Jain, M., Mischnik, M., Pelzing, M., Martin, K., & 9 others, Feb 1 2022, In: Journal of Clinical Medicine. 11, 3, 630.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2021
Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells
Zhang, P., Nguyen, J., Abdulla, F., Nelson, A. T., Beckman, J. D., Vercellotti, G. M. & Belcher, J. D., Mar 26 2021, In: Frontiers in immunology. 12, 632709.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2020
A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease
McArthur, J. G., Svenstrup, N., Chen, C., Fricot, A., Carvalho, C., Nguyen, J., Nguyen, P., Parachikova, A., Abdulla, F., Vercellotti, G. M., Hermine, O., Edwards, D., Ribeil, J. A., Belcher, J. D. & Maciel, T. T., Mar 1 2020, In: Haematologica. 105, 3, p. 623-631 9 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2019
Critical role of C5a in sickle cell disease
Vercellotti, G. M., Dalmasso, A. P., Schaid, T. R., Nguyen, J., Chen, C., Ericson, M. E., Abdulla, F., Killeen, T., Lindorfer, M. A., Taylor, R. P. & Belcher, J. D., Mar 2019, In: American Journal of Hematology. 94, 3, p. 327-337 11 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2018
Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction
Belcher, J. D., Chen, C., Nguyen, J., Abdulla, F., Zhang, P., Nguyen, H., Nguyen, P., Killeen, T., Miescher, S. M., Brinkman, N., Nath, K. A., Steer, C. J. & Vercellotti, G. M., Apr 2018, In: PloS one. 13, 4, e0196455.Research output: Contribution to journal › Article › peer-review
Open Access76 Scopus citations -
Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vasoocclusion, inflammation and anemia
Belcher, J. D., Gomperts, E., Nguyen, J., Chen, C., Abdulla, F., Kiser, Z. M., Gallo, D., Levy, H., Otterbein, L. E. & Vercellotti, G. M., Oct 2018, In: PloS one. 13, 10, e0205194.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2017
Control of Oxidative Stress and Inflammation in Sickle Cell Disease with the Nrf2 Activator Dimethyl Fumarate
Belcher, J. D., Chen, C., Nguyen, J., Zhang, P., Abdulla, F., Nguyen, P., Killeen, T., Xu, P., O'Sullivan, G., Nath, K. A. & Vercellotti, G. M., May 10 2017, In: Antioxidants and Redox Signaling. 26, 14, p. 748-762 15 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
2016
Hepatic overexpression of hemopexin inhibits inflammation and vascular stasis in murine models of sickle cell disease
Vercellotti, G. M., Zhang, P., Nguyen, J., Abdulla, F., Chen, C., Nguyen, P., Nowotny, C., Steer, C. J., Smith, A. & Belcher, J. D., 2016, In: Molecular Medicine. 22, p. 437-451 15 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
2015
The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-κB activation in transgenic sickle mice
Belcher, J. D., Chen, C., Nguyen, J., Abdulla, F., Nguyen, P., Nguyen, M., Okeley, N. M., Benjamin, D. R., Senter, P. D. & Vercellotti, G. M., Feb 23 2015, In: PloS one. 10, 2, e0117772.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
2014
Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease
Belcher, J. D., Chen, C., Nguyen, J., Milbauer, L., Abdulla, F., Alayash, A. I., Smith, A., Nath, K. A., Hebbel, R. P. & Vercellotti, G. M., Jan 16 2014, In: Blood. 123, 3, p. 377-390 14 p.Research output: Contribution to journal › Article › peer-review
Open Access480 Scopus citations -
2010
Endothelial nitric oxide synthase and nitric oxide regulate endothelial tissue factor expression in vivo in the sickle transgenic mouse
Solovey, A., Kollander, R., Milbauer, L., Abdulla, F., Chen, Y., Kelm, R. J. & Hebbel, R. P., Jan 2010, In: American Journal of Hematology. 85, 1, p. 41-45 5 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Nuclear factor-kappa B (NFκB) component p50 in blood mononuclear cells regulates endothelial tissue factor expression in sickle transgenic mice: implications for the coagulopathy of sickle cell disease
Kollander, R., Solovey, A., Milbauer, L., Abdulla, F., Kelm, R. J. & Hebbel, R. P., Apr 2010, In: Translational Research. 155, 4, p. 170-177 8 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice
Hebbel, R. P., Vercellotti, G. M., Pace, B. S., Solovey, A. N., Kollander, R., Abanonu, C. F., Nguyen, J., Vineyard, J. V., Belcher, J. D., Abdulla, F., Osifuye, S., Eaton, J. W., Kelm, R. J. & Slungaard, A., Mar 25 2010, In: Blood. 115, 12, p. 2483-2490 8 p.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations