20092020
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Research Output 2009 2019

2019
6 Citations (Scopus)

Adaptive NK cell reconstitution is associated with better clinical outcomes

Cichocki, F., Taras, E., Chiuppesi, F., Wagner, J. E., Blazar, B. R., Brunstein, C., Luo, X., Diamond, D. J., Cooley, S., Weisdorf, D. J. & Miller, J. S., Jan 24 2019, In : JCI Insight. 4, 2, Y.

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
Cytomegalovirus
Transplants
Hematologic Neoplasms
Hematopoietic Stem Cells
1 Citation (Scopus)

Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming

Merino, A., Zhang, B., Dougherty, P., Luo, X., Wang, J., Blazar, B. R., Miller, J. S. & Cichocki, F., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3770-3785 16 p.

Research output: Contribution to journalArticle

Open Access
Epigenomics
Natural Killer Cells
NK Cell Lectin-Like Receptor Subfamily C
Genome
T-Lymphocytes

Human NK cell development: One road or many?

Cichocki, F., Grzywacz, B. & Miller, J. S., Jan 1 2019, In : Frontiers in immunology. 10, AUG, Article 2078.

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
Linear Models
Up-Regulation
KIR Receptors
Lymphoid Tissue
1 Citation (Scopus)

Setting traps for NKG2A gives NK cell immunotherapy a fighting chance

Cichocki, F. M. & Miller, J. S., May 1 2019, In : Journal of Clinical Investigation. 129, 5, p. 1839-1841 3 p.

Research output: Contribution to journalReview article

Natural Killer Cells
Immunotherapy
Adoptive Transfer
Endoplasmic Reticulum
Neoplasms

The association of CMV with NK-cell reconstitution depends on graft source: Results from BMT CTN-0201 samples

Rashidi, A., Luo, X., Cooley, S., Anasetti, C., Waller, E. K., Brunstein, C. G., Cichocki, F., Weisdorf, D. J. & Miller, J. S., Aug 27 2019, In : Blood Advances. 3, 16, p. 2465-2469 5 p.

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
Transplants
trans-crotonin
2018
12 Citations (Scopus)

Adaptive NK cells resist regulatory T-cell suppression driven by IL37

Sarhan, D., Hippen, K. L., Lemire, A., Hying, S., Luo, X., Lenvik, T., Curtsinger, J., Davis, Z., Zhang, B., Cooley, S., Cichocki, F., Blazar, B. R. & Miller, J. S., Jul 2018, In : Cancer Immunology Research. 6, 7, p. 766-775 10 p.

Research output: Contribution to journalArticle

Open Access
Regulatory T-Lymphocytes
Natural Killer Cells
Natural Killer Cell Receptors
Tumor Microenvironment
Programmed Cell Death 1 Receptor
12 Citations (Scopus)

ARID5B regulates metabolic programming in human adaptive NK cells

Cichocki, F. M., Wu, C-Y., Zhang, B., Felices, M., Tesi, B., Tuininga, K., Dougherty, P., Taras, E., Hinderlie, P., Blazar, B. R., Bryceson, Y. T. & Miller, J. S., 2018, In : Journal of Experimental Medicine. 215, 9, p. 2379-2395 17 p.

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
Mitochondrial Membrane Potential
Electron Transport
Cytomegalovirus
Chromatin
10 Citations (Scopus)

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells

Burrack, K. S., Huggins, M. A., Taras, E., Dougherty, P., Henzler, C. M., Yang, R., Alter, S., Jeng, E. K., Wong, H. C., Felices, M., Cichocki, F., Miller, J. S., Hart, G. T., Johnson, A. J., Jameson, S. C. & Hamilton, S. E., Apr 17 2018, In : Immunity. 48, 4, p. 760-772.e4

Research output: Contribution to journalArticle

Open Access
Cerebral Malaria
Interleukin-15
Natural Killer Cells
Interleukin-10
Blood-Brain Barrier
2017
23 Citations (Scopus)

GSK3 inhibition drives maturation of NK cells and enhances their antitumor activity

Cichocki, F. M., Valamehr, B., Bjordahl, R., Zhang, B., Rezner, B., Rogers, P., Gaidarova, S., Moreno, S., Tuininga, K., Dougherty, P., McCullar, V., Howard, P., Sarhan, D., Taras, E., Schlums, H., Abbot, S., Shoemaker, D., Bryceson, Y. T., Blazar, B. R., Wolchko, S. & 2 others, Cooley, S. A. & Miller, J. S., Oct 15 2017, In : Cancer Research. 77, 20, p. 5664-5675 12 p.

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
Neoplasms
Phosphotransferases
Immunologic Monitoring
Interleukin-15
2016
5 Citations (Scopus)

Activating Receptor Signals Drive Receptor Diversity in Developing Natural Killer Cells

Freund, J., May, R. M., Yang, E., Li, H., McCullen, M., Zhang, B., Lenvik, T., Cichocki, F., Anderson, S. K. & Kambayashi, T., Aug 8 2016, In : PLoS biology. 14, 8, e1002526.

Research output: Contribution to journalArticle

natural killer cells
Natural Killer Cells
Ligands
receptors
KIR Receptors
45 Citations (Scopus)

Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells

Sarhan, D., Cichocki, F., Zhang, B., Yingst, A., Spellman, S. R., Cooley, S., Verneris, M. R., Blazar, B. R. & Miller, J. S., Oct 1 2016, In : Cancer Research. 76, 19, p. 5696-5706 11 p.

Research output: Contribution to journalArticle

Natural Killer Cells
T-Lymphocytes
Reactive Oxygen Species
Costimulatory and Inhibitory T-Cell Receptors
Neoplasms
93 Citations (Scopus)

CD56 dim CD57+ NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT

Cichocki, F., Cooley, S., Davis, Z., DeFor, T. E., Schlums, H., Zhang, B., Brunstein, C. G., Blazar, B. R., Wagner, J., Diamond, D. J., Verneris, M. R., Bryceson, Y. T., Weisdorf, D. J. & Miller, J. S., Feb 1 2016, In : Leukemia. 30, 2, p. 456-463 8 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Natural Killer Cells
Leukemia
Transplants
Recurrence
29 Citations (Scopus)

Diversification and functional specialization of human NK cell subsets

Cichocki, F., Schlums, H., Theorell, J., Tesi, B., Miller, J. S., Ljunggren, H. G. & Bryceson, Y. T., Feb 1 2016, In : Current Topics in Microbiology and Immunology. 395, p. 63-93 31 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Immunologic Monitoring
Immunity
Cytokines
Disease Susceptibility
19 Citations (Scopus)

Epigenetic Regulation of Adaptive NK Cell Diversification

Tesi, B., Schlums, H., Cichocki, F. & Bryceson, Y. T., Jul 1 2016, In : Trends in Immunology. 37, 7, p. 451-461 11 p.

Research output: Contribution to journalReview article

Epigenomics
Natural Killer Cells
Genetic Epigenesis
T Lymphocyte Differentiation Antigens
Cytomegalovirus Infections
17 Citations (Scopus)
Adoptive Transfer
Cell Transplantation
Natural Killer Cells
Transplants
Neoplasms
2015
30 Citations (Scopus)
KIR Receptors
Cell Transplantation
Cytomegalovirus
Natural Killer Cells
Tissue Donors
261 Citations (Scopus)

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function

Schlums, H., Cichocki, F., Tesi, B., Theorell, J., Beziat, V., Holmes, T. D., Han, H., Chiang, S. C. C., Foley, B., Mattsson, K., Larsson, S., Schaffer, M., Malmberg, K. J., Ljunggren, H. G., Miller, J. S. & Bryceson, Y. T., Mar 17 2015, In : Immunity. 42, 3, p. 443-456 14 p.

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Epigenomics
Natural Killer Cells
Virus Diseases
Myeloid Cells
10 Citations (Scopus)

Human natural killer cell microRNA: Differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs

Presnell, S. R., Al-Attar, A., Cichocki, F., Miller, J. S. & Lutz, C. T., Jan 24 2015, In : Genes and Immunity. 16, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Natural Killer Cells
Genes
Cell Differentiation
T-Lymphocytes
11 Citations (Scopus)

Successful treatment of mast cell activation syndrome with sunitinib

Afrin, L. B., Cichocki, F. M., Patel, K. & Molderings, G. J., Dec 1 2015, In : European Journal of Haematology. 95, 6, p. 595-597 3 p.

Research output: Contribution to journalArticle

Mast Cells
Systemic Mastocytosis
Therapeutics
Hypersensitivity
Mastocytosis
9 Citations (Scopus)

UNC-45A is a nonmuscle myosin IIA chaperone required for NK cell cytotoxicity via control of lytic granule secretion

Iizuka, Y., Cichocki, F. M., Sieben, A., Sforza, F., Karim, R., Coughlin, K., Vogel, R. I., Gavioli, R., Mc Cullar, V. J., Lenvik, T. R., Lee, M. K., Miller, J. S. & Bazzaro, M., Nov 15 2015, In : Journal of Immunology. 195, 10, p. 4760-4770 11 p.

Research output: Contribution to journalArticle

Nonmuscle Myosin Type IIA
Natural Killer Cells
Wiskott-Aldrich Syndrome Protein
Immunological Synapses
Actin Depolymerizing Factors
2014
32 Citations (Scopus)

NK cell development and function - Plasticity and redundancy unleashed

Cichocki, F., Sitnicka, E. & Bryceson, Y. T., Apr 2014, In : Seminars in Immunology. 26, 2, p. 114-126 13 p.

Research output: Contribution to journalReview article

Natural Killer Cells
Cell Differentiation
Immunologic Monitoring
Lymphocyte Subsets
Population Genetics
53 Citations (Scopus)

The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT)

Foley, B., Felices, M., Cichocki, F., Cooley, S., Verneris, M. R. & Miller, J. S., Mar 2014, In : Immunological Reviews. 258, 1, p. 45-63 19 p.

Research output: Contribution to journalReview article

Natural Killer Cell Receptors
Cell Transplantation
Natural Killer Cells
Major Histocompatibility Complex
Immunologic Memory
18 Citations (Scopus)

Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency

Cichocki, F., Schlums, H., Li, H., Stache, V., Holmes, T., Lenvik, T. R., Chiang, S. C. C., Miller, J. S., Meeths, M., Anderson, S. K. & Bryceson, Y. T., Jun 2014, In : Journal of Experimental Medicine. 211, 6, p. 1079-1091 13 p.

Research output: Contribution to journalArticle

Lymphocytes
Mutation
Chromatin Assembly and Disassembly
T-Lymphocytes
Natural Killer Cells
2013
38 Citations (Scopus)

Epigenetic regulation of NK cell differentiation and effector functions

Cichocki, F., Miller, J. S., Anderson, S. K. & Bryceson, Y. T., Sep 16 2013, In : Frontiers in immunology. 4, FRB, Article 55.

Research output: Contribution to journalReview article

Epigenomics
Natural Killer Cells
Cell Differentiation
Cytokines
Cell Communication
15 Citations (Scopus)

Identification of a KIR antisense lncRNA expressed by progenitor cells

Wright, P. W., Huehn, A., Cichocki, F., Li, H., Sharma, N., Dang, H., Lenvik, T. R., Woll, P., Kaufman, D., Miller, J. S. & Anderson, S. K., Jul 19 2013, In : Genes and Immunity. 14, 7, p. 427-433 7 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
KIR Receptors
Stem Cells
Zinc Fingers
Natural Killer Cells
2012
42 Citations (Scopus)

CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells

Björkström, N. K., Béziat, V., Cichocki, F., Liu, L. L., Levine, J., Larsson, S., Koup, R. A., Anderson, S. K., Ljunggren, H. G. & Malmberg, K. J., Oct 25 2012, In : Blood. 120, 17, p. 3455-3465 11 p.

Research output: Contribution to journalArticle

KIR Receptors
T-cells
Natural Killer Cells
T-Lymphocytes
Ligands
147 Citations (Scopus)

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

Gleason, M. K., Lenvik, T. R., McCullar, V., Felices, M., O'Brien, M. S., Cooley, S. A., Verneris, M. R., Cichocki, F., Holman, C. J., Panoskaltsis-Mortari, A., Niki, T., Hirashima, M., Blazar, B. R. & Miller, J. S., Mar 29 2012, In : Blood. 119, 13, p. 3064-3072 9 p.

Research output: Contribution to journalArticle

Natural Killer Cell Receptors
Galectins
Natural Killer Cells
Interferon-gamma
Cells
2011
106 Citations (Scopus)

Cutting edge: MicroRNA-181 promotes human NK cell development by regulating notch signaling

Cichocki, F. M., Felices, M., Mc Cullar, V. J., Presnell, S. R., Al-Attar, A., Lutz, C. T. & Miller, J. S., Dec 15 2011, In : Journal of Immunology. 187, 12, p. 6171-6175 5 p.

Research output: Contribution to journalArticle

MicroRNAs
Natural Killer Cells
Phosphotransferases
Human Development
Cell Lineage
26 Citations (Scopus)

Killer immunoglobulin-like receptor transcriptional regulation: A fascinating dance of multiple promoters

Cichocki, F., Miller, J. S. & Anderson, S. K., Apr 1 2011, In : Journal of Innate Immunity. 3, 3, p. 242-248 7 p.

Research output: Contribution to journalReview article

Dancing
KIR Receptors
Natural Killer Cells
Major Histocompatibility Complex
Untranslated RNA
2010
15 Citations (Scopus)
Natural Killer Cell Receptors
Human Development
Natural Killer Cells
Immunoglobulins
Cell Differentiation
46 Citations (Scopus)

KIR antisense transcripts are processed into a 28-base PIWI-like RNA in human NK cells

Cichocki, F., Lenvik, T., Sharma, N., Yun, G., Anderson, S. K. & Miller, J. S., Aug 15 2010, In : Journal of Immunology. 185, 4, p. 2009-2012 4 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Transcriptional Silencer Elements
RNA
DNA Transposable Elements
Cell Lineage
2009
29 Citations (Scopus)

The transcription factor c-Myc enhances KIR gene transcription through direct binding to an upstream distal promoter element

Cichocki, F., Hanson, R. J., Lenvik, T., Pitt, M., McCullar, V., Li, H., Anderson, S. K. & Miller, J. S., Apr 2 2009, In : Blood. 113, 14, p. 3245-3253 9 p.

Research output: Contribution to journalArticle

KIR Receptors
Transcription
Transcription Factors
Genes
Natural Killer Cells