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Research interests
Miller Lab Consortium. To date, our team has treated more than 400 patients with natural killer cell infusions and over a hundred patients with therapies that activate their own natural killer cells. We've retrospectively analyzed more than 5000 patients and enrolled more than 500 patients in prospective trials.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting off-the-shelf iPSC-derived natural killer cells against solid tumors
Miller, J. S. (PI), Antonarakis, E. (CoI), Chen, C. C. (CoI), Cichocki, F. M. (CoI), Davis, Z. B. (CoI), Dehm, S. M. (CoI), Felices, M. (CoI), Luo, X. (CoI) & Provenzano, P. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
8/1/23 → 7/31/30
Project: Research project
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Off-the-Shelf Immune Effector Cells for Hematological Malignancies
Wagner, J. E. (PI), Bachanova, V. (CoI), Betts, B. (CoI), Brunstein, C. G. (CoI), Cichocki, F. M. (CoI), De For, T. E. (CoI), Eaton, A. (CoI), Hippen, K. L. (CoI), Luo, X. (CoI), Maakaron, J. (CoI), McKenna, D. H. (CoI) & Tolar, J. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
5/5/23 → 4/30/28
Project: Research project
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Bcl11b: A Master Transcription Factor Controlling Human NK Cell Development
Cichocki, F. M. (PI), Eaton, A. (CoI), Felices, M. (CoI) & Wang, J. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
7/1/21 → 4/30/26
Project: Research project
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NK cells, their receptors, and cancer therapy
Miller, J. S. (PI), Bachanova, V. (CoI), Basu, S. (CoI), Brunstein, C. G. (CoI), Cichocki, F. M. (CoI), Felices, M. (CoI), Geller, M. A. (CoI), Grzywacz, B. J. (CoI), Le, C. T. (CoI), Luo, X. (CoI), Starr, T. (CoI), Walcheck, B. (CoI), Warlick, E. D. (CoI) & Weisdorf, D. J. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
4/9/21 → 3/31/26
Project: Research project
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Development of NK Cell Therapeutics
Miller, J. S. (PI), Cichocki, F. M. (CoI) & Felices, M. (CoI)
1/1/20 → 12/31/22
Project: Research project
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Chimeric antigen receptor therapies: Development, design, and implementation
Lee, M. J., Cichocki, F. & Miller, J. S., 2025, (Accepted/In press) In: Journal of Allergy and Clinical Immunology.Research output: Contribution to journal › Review article › peer-review
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Expression Patterns of DLL3 across Neuroendocrine and Non-neuroendocrine Neoplasms Reveal Broad Opportunities for Therapeutic Targeting
Lozada, J. R., Elliott, A., Evans, M. G., Wacker, J., Storey, K. M., Egusa, E. A., Zorko, N. A., Kumar, A., Crymes, A., Heath, E. I., Carneiro, B. A., Soares, H. P., Cichocki, F. M., Miller, J. S., Lou, E., Beltran, H., Antonarakis, E. S., Ryan, C. & Hwang, J., Feb 1 2025, In: Cancer Research Communications. 5, 2, p. 318-326 9 p.Research output: Contribution to journal › Article › peer-review
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Integrated ATAC-seq and RNA-seq analysis identifies key regulatory elements in NK cells activated with feeder cells and IL-2
Motallebnejad, P., Lee, Z., One, J., Cichocki, F., Hu, W.-S. & Azarin, S. M., 2025, (Accepted/In press) In: Bioengineering and Translational Medicine.Research output: Contribution to journal › Article › peer-review
Open Access -
High-dimensional single-cell analysis of human natural killer cell heterogeneity
Rebuffet, L., Melsen, J. E., Escalière, B., Basurto-Lozada, D., Bhandoola, A., Björkström, N. K., Bryceson, Y. T., Castriconi, R., Cichocki, F., Colonna, M., Davis, D. M., Diefenbach, A., Ding, Y., Haniffa, M., Horowitz, A., Lanier, L. L., Malmberg, K. J., Miller, J. S., Moretta, L. & Narni-Mancinelli, E. & 7 others, , Aug 2024, In: Nature immunology. 25, 8, p. 1474-1488 15 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
Microfluidic Organoid Cultures Derived from Pancreatic Cancer Biopsies for Personalized Testing of Chemotherapy and Immunotherapy
Choi, D., Gonzalez-Suarez, A. M., Dumbrava, M. G., Medlyn, M., de Hoyos-Vega, J. M., Cichocki, F., Miller, J. S., Ding, L., Zhu, M., Stybayeva, G., Gaspar-Maia, A., Billadeau, D. D., Ma, W. W. & Revzin, A., Feb 2 2024, In: Advanced Science. 11, 5, 2303088.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations