Frank G Ondrey

1988 …2020

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Article
2020

Effects of PPAR-γ agonists on oral cancer cell lines: Potential horizons for chemopreventives and adjunctive therapies

Hall, J. A., Rusten, M., Abughazaleh, R. D., Wuertz, B., Souksavong, V., Escher, P. & Ondrey, F., Sep 1 2020, In : Head and Neck. 42, 9, p. 2542-2554 13 p.

Research output: Contribution to journalArticle

Retinoids augment thiazolidinedione PPARγ activation in oral cancer cells

Rosas, R., Buryska, S., Silver, R., Wuertz, B. R. & Ondrey, F., Jun 1 2020, In : Anticancer Research. 40, 6, p. 3071-3080 10 p.

Research output: Contribution to journalArticle

2019

Chemoprevention of lung carcinogenesis by dietary nicotinamide and inhaled budesonide

Galbraith, A. R., Seabloom, D. E., Wuertz, B. R., Antonides, J. D., Steele, V. E., Wattenberg, L. W. & Ondrey, F. G., Feb 2019, In : Cancer Prevention Research. 12, 2, p. 69-78 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

Effects of talactoferrin alpha on lung adenoma prevention in A/J mice june 2, 2016

Seabloom, D. E., Galbraith, A. R., Haynes, A. M., Fujita, A. S., Antonides, J. D., Wuertz, B. R., Steele, V. E., Ondrey, F. G. & Wattenberg, L. W., 2018, In : American Journal of Translational Research. 10, 3, p. 875-880 6 p., AJTR0033800.

Research output: Contribution to journalArticle

Pepsin: Biomarker, mediator, and therapeutic target for reflux and aspiration

Johnston, N., Dettmar, P. W., Ondrey, F. G., Nanchal, R., Lee, S. H. & Bock, J. M., Jan 1 2018, (Accepted/In press) In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalArticle

6 Scopus citations

PPARγ-Mediated p21 Induction in Aerodigestive Preneoplastic Cell Lines

Miller, W. A., Wuertz, B. R. & Ondrey, F. G., Oct 1 2018, In : Annals of Otology, Rhinology and Laryngology. 127, 10, p. 677-686 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Fixed-Dose combinations of pioglitazone & metformin for lung cancer prevention

Seabloom, D. E., Galbraith, A. R., Haynes, A. M., Antonides, J. D., RWuertz, B., Miller, W. A., Miller, K. A., Steele, V. E., Miller, M. S., Clapper, M. L., O'sullivan, M. G. & Ondrey, F. G., Feb 2017, In : Cancer Prevention Research. 10, 2, p. 116-123 8 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Functional activation of PPARγ in human upper aerodigestive cancer cell lines

Wright, S. K., Wuertz, B. R., Harris, G., Abu Ghazallah, R., Miller, W. A., Gaffney, P. M. & Ondrey, F. G., Jan 1 2017, In : Molecular Carcinogenesis. 56, 1, p. 149-162 14 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

PPARγ targeted oral cancer treatment and additional utility of genomics analytic techniques

Handley, N., Eide, J., Taylor, R., Wuertz, B., Gaffney, P. & Ondrey, F., Apr 1 2017, In : Laryngoscope. 127, 4, p. E124-E131

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Safety & preclinical efficacy of aerosol pioglitazone on lung adenoma Prevention in A/J Mice

Seabloom, D. E., Galbraith, A. R., Haynes, A. M., Antonides, J. D., RWuertz, B., Miller, W. A., Miller, K. A., Steele, V. E., Suen, C. S., O'sullivan, M. G. & Ondrey, F. G., Feb 2017, In : Cancer Prevention Research. 10, 2, p. 124-132 9 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Thiazolidinediones abrogate cervical cancer growth

Wuertz, B. R., Darrah, L., Wudel, J. & Ondrey, F. G., Apr 15 2017, In : Experimental Cell Research. 353, 2, p. 63-71 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Airway reflux

Johnston, N., Ondrey, F., Rosen, R., Hurley, B. P., Gould, J., Allen, J., DelGaudio, J. & Altman, K. W., Oct 1 2016, In : Annals of the New York Academy of Sciences. 1381, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Correlation analysis of oral lesion sizes by various standardized criteria

Flanagan, C. E., Rhodus, N. L., Cole, K. A., Szabo, E. & Ondrey, F. G., Nov 1 2016, In : American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 37, 6, p. 502-506 5 p.

Research output: Contribution to journalArticle

Open Access
2014

Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma

Unger, G. M., Kren, B. T., Korman, V. L., Kimbrough, T. G., Vogel, R. I., Ondrey, F. G., Trembley, J. H. & Ahmed, K., Aug 2014, In : Molecular Cancer Therapeutics. 13, 8, p. 2018-2029 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

N-methylnitrosourea-induced carcinoma as a model for laryngeal carcinogenesis

Caicedo-Granados, E., Galbraith, A. R., Schachern, M. G., Hartle, D. E., Wattenberg, L. W., Wuertz, B. R., Keel, S., Yueh, B. & Ondrey, F. G., Dec 1 2014, In : Head and Neck. 36, 12, p. 1802-1806 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Phase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer

Cohen, E. E. W., Karrison, T. G., Kocherginsky, M., Mueller, J., Egan, R., Huang, C. H., Brockstein, B. E., Agulnik, M. B., Mittal, B. B., Yunus, F., Samant, S., Raez, L. E., Mehra, R., Kumar, P., Ondrey, F., Marchand, P., Braegas, B., Seiwert, T. Y., Villaflor, V. M., Haraf, D. J. & 1 others, Vokes, E. E., Sep 1 2014, In : Journal of Clinical Oncology. 32, 25, p. 2735-2743 9 p.

Research output: Contribution to journalArticle

260 Scopus citations
17 Scopus citations

Randomized safety and efficacy study of fosbretabulin with paclitaxel/carboplatin against anaplastic thyroid carcinoma

Sosa, J. A., Elisei, R., Jarzab, B., Balkissoon, J., Lu, S. P., Bal, C., Marur, S., Gramza, A., Yosef, R. B., Gitlitz, B., Haugen, B. R., Ondrey, F., Lu, C., Karandikar, S. M., Khuri, F., Licitra, L. & Remick, S. C., Feb 1 2014, In : Thyroid. 24, 2, p. 232-240 9 p.

Research output: Contribution to journalArticle

87 Scopus citations
2012

A comparison of screening methods in two early phase oral leukoplakia clinical trials

Rosas, R. R., Cole, K. A., Darrah, L., Rohrer, M. D., Rhodus, N. L. & Ondrey, F. G., Oct 2012, In : Oral Diseases. 18, 7, p. 720-723 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Enforced expression of nuclear factor kappa B in p53 deficient keratinocytes induces cell cycle, angiogenic potential and tumorigenesis

Caicedo-Granados, E. E., Wuertz, B. R. & Ondrey, F. G., Apr 1 2012, In : Oral Oncology. 48, 4, p. 303-310 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Id2 regulates the proliferation of squamous cell carcinoma in vitro via the NF-κB/cyclin D1 pathway

Wang, C., Chen, Q., Hamajima, Y., Sun, W., Zheng, Y. Q., Hu, X. H., Ondrey, F. G. & Lin, J. Z., Sep 28 2012, In : Chinese Journal of Cancer. 31, 9, p. 430-439 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Thyroidectomy followed by fosbretabulin (CA4P) combination regimen appears to suggest improvement in patient survival in anaplastic thyroid cancer

Sosa, J. A., Balkissoon, J., Lu, S. P., Langecker, P., Elisei, R., Jarzab, B., Bal, C. S., Marur, S., Gramza, A. & Ondrey, F. G., Dec 1 2012, In : Surgery (United States). 152, 6, p. 1078-1087 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
2011

Identification of pro-differentiation patterns by gene expression analysis following pioglitazone treatment in a primary laryngeal tumor cell line

Handley, N. R., Gaffney, P. M., Taylor, R. S., Wuertz, B. R. & Ondrey, F. G., Aug 29 2011, In : Laryngoscope. 121, SUPPL. 5, p. S281

Research output: Contribution to journalArticle

Interleukin-8 production in response to tumor necrosis factor-alpha by cholesteatoma keratinocytes in cell culture

Hilton, C. W., Ondrey, F. G., Wuertz, B. R. & Levine, S. C., Feb 1 2011, In : Laryngoscope. 121, 2, p. 372-374 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

The effect of indomethacin on paclitaxel sensitivity and apoptosis in oral squamous carcinoma cells: The role of nuclear factor-κb inhibition

Caicedo-Granados, E. E., Wuertz, B. R., Marker, P. H., Lee, G. S. & Ondrey, F. G., Aug 1 2011, In : Archives of Otolaryngology - Head and Neck Surgery. 137, 8, p. 799-805 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Tobacco carcinogen mediated up-regulation of AP-1 dependent pro-angiogenic cytokines in head and neck carcinogenesis

Swenson, W. G., Wuertz, B. R. K. & Ondrey, F. G., Sep 1 2011, In : Molecular Carcinogenesis. 50, 9, p. 668-679 12 p.

Research output: Contribution to journalArticle

20 Scopus citations
2010
50 Scopus citations

Cigarette smoke condensate induces nuclear factor kappa-B activity and proangiogenic growth factors in aerodigestive cells

Rohrer, J., Wuertz, B. R. K. & Ondrey, F., Aug 1 2010, In : Laryngoscope. 120, 8, p. 1609-1613 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Conference report: Eighth Annual AACR International Conference on frontiers in cancer prevention research

Brewster, A. M., Patterson, S. L., Forman, M. R., Hughes-Halbert, C., Limburg, P. J., Ondrey, F. G., Paskett, E. D., Wetter, D. W. & Hawk, E. T., Aug 2010, In : Cancer Prevention Research. 3, 8, p. 1044-1048 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Inhibitor of differentiation 1 contributes to head and neck squamous cell carcinoma survival via the NF-κB/survivin and phosphoinositide 3-kinase/Akt signaling pathways

Lin, J., Guan, Z., Wang, C., Feng, L., Zheng, Y., Caicedo, E., Bearth, E., Peng, J. R., Gaffney, P. & Ondrey, F. G., Jan 1 2010, In : Clinical Cancer Research. 16, 1, p. 77-87 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Quantitative proteomics reveals myosin and actin as promising saliva biomarkers for distinguishing pre-malignant and malignant oral lesions

de Jong, E. P., Xie, H., Onsongo, G., Stone, M. D., Chen, X. B., Kooren, J. A., Refsland, E. W., Griffin, R. J., Ondrey, F. G., Wu, B., Le, C. T., Rhodus, N. L., Carlis, J. V. & Griffin, T. J., 2010, In : PloS one. 5, 6, e11148.

Research output: Contribution to journalArticle

72 Scopus citations

The role of inhibitor of DNA-binding (Id1) in hyperproliferation of keratinocytes: The pathological basis for middle ear cholesteatoma from chronic otitis media

Hamajima, Y., Komori, M., Preciado, D. A., Choo, D. I., Moribe, K., Murakami, S., Ondrey, F. G. & Lin, J., Oct 2010, In : Cell Proliferation. 43, 5, p. 457-463 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2009

Determining the effect of imiquimod on human endothelial cells

Meyer, A. C., Wuertz, B. R. K., Sidman, J. D. & Ondrey, F. G., Dec 1 2009, In : Laryngoscope. 119, SUPPL.3, p. S312

Research output: Contribution to journalArticle

Expression of fibroblast growth factor binding protein in head and neck cancer

Li, W., Wang, C., Juhn, S. S., Ondrey, F. G. & Lin, J., Sep 1 2009, In : Archives of Otolaryngology - Head and Neck Surgery. 135, 9, p. 896-901 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Ototoxicity after combined platinum and fractionated radiation in a novel guinea pig model

Miller, M. W., Riedel, G., Hoistad, D., Sutherland, C., Juhn, S. S., Adams, G. L., Griffin, R. & Ondrey, F. G., Jan 1 2009, In : American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 30, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
106 Scopus citations
2008

Pilot randomized phase II study of celecoxib in oral premalignant lesions

Papadimitrakopoulou, V. A., William, W. N., Dannenberg, A. J., Lippman, S. M., Lee, J. J., Ondrey, F. G., Peterson, D. E., Feng, L., Atwell, A., El-Naggar, A. K., Nathan, C. A., Helman, J. I., Du, B., Yueh, B. & Boyle, J. O., Apr 1 2008, In : Clinical Cancer Research. 14, 7, p. 2095-2101 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

Presence of otitis media with effusion and its risk factors affect serum cytokine profile in children

Johnston, B. N. A., Preciado, D. A., Ondrey, F. G. & Daly, K. A., Feb 1 2008, In : International Journal of Pediatric Otorhinolaryngology. 72, 2, p. 209-214 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

TNF-α drives matrix metalloproteinase-9 in squamous oral carcinogenesis

Hohberger, L., Wuertz, B. R. K., Xie, H., Griffin, T. & Ondrey, F., Aug 1 2008, In : Laryngoscope. 118, 8, p. 1395-1399 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
2007

A method of producing carcinoma in upper aerodigestive tree and esophagus of the Syrian golden hamster using wounding and instillation of N-methylnitrosourea

Estensen, R. D., Anderson, W. R., Galbraith, A. R., Hartle, D. E., Jordan, M. M., Ondrey, F. G. & Wattenberg, L. W., Aug 1 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 8, p. 1644-1650 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Efficacy of an osmotic pump delivered, GM-CSF-based tumor vaccine in the treatment of upper aerodigestive squamous cell carcinoma in rats

Djalilian, H. R., Caicedo, E., Lessan, K., Grami, V., Le, C. T., Spellman, S. R., Pambuccian, S., Hall, W. A., Low, W. C. & Ondrey, F. G., Aug 2007, In : Cancer Immunology, Immunotherapy. 56, 8, p. 1207-1214 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Id1 induces the proliferation of cochlear sensory epithelial cells via the nuclear factor-κB/cyclin D1 pathway in vitro

Ozeki, M., Hamajima, Y., Feng, L., Ondrey, F. G., Schlentz, E. & Lin, J., Feb 15 2007, In : Journal of Neuroscience Research. 85, 3, p. 515-524 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Inositol hexaphosphate and paclitaxel: Symbiotic treatment of oral cavity squamous cell carcinoma

Janus, S. C., Weurtz, B. & Ondrey, F. G., Aug 1 2007, In : Laryngoscope. 117, 8, p. 1381-1388 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
12 Scopus citations

Th1/Th2 cytokine ratio in tissue transudates from patients with oral lichen planus

Rhodus, N. L., Cheng, B. & Ondrey, F., Mar 19 2007, In : Mediators of inflammation. 2007, 19854.

Research output: Contribution to journalArticle

56 Scopus citations
2006

Decreased hearing after combined modality therapy for head and neck cancer

Pearson, S. E., Meyer, A. C., Adams, G. L. & Ondrey, F. G., Mar 1 2006, In : American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 27, 2, p. 76-80 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma

Patel, K. J., Pambuccian, S. E., Ondrey, F. G., Adams, G. L. & Gaffney, P. M., Nov 1 2006, In : Oral Oncology. 42, 10, p. 994-1004 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Proinflammatory cytokine levels in saliva before and after treatment of (erosive) oral lichen planus with dexamethasone

Rhodus, N. L., Cheng, B., Bowles, W., Myers, S., Miller, L. & Ondrey, F., Mar 1 2006, In : Oral Diseases. 12, 2, p. 112-116 5 p.

Research output: Contribution to journalArticle

68 Scopus citations
2005
109 Scopus citations

A pilot study of longitudinal serum cytokine and angiogenesis factor levels as markers of therapeutic response and survival in patients with head and neck squamous cell carcinoma

Druzgal, C. H., Chen, Z., Yeh, N. T., Thomas, G. R., Ondrey, F. G., Duffey, D. C., Vilela, R. J., Ende, K., McCullagh, L., Rudy, S. F., Muir, C., Herscher, L. L., Morris, J. C., Albert, P. S. & Van Waes, C., Sep 1 2005, In : Head and Neck. 27, 9, p. 771-784 14 p.

Research output: Contribution to journalArticle

77 Scopus citations