20102015

Research output per year

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Personal profile

Research interests

My research interest is focused on the discovery, the elucidation of the mode of action of natural and natural-based products as well as their promotion as high added-value bioactive compounds, mainly as therapeutic and anticancer agents.

I obtained my BSc and MSc at the University of Strasbourg (Strasbourg, France) and completed my PhD at the Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (Luxembourg, Grand Duchy of Luxembourg) in the framework of the European RedCat Project. As Marie Curie Fellow, my research project focused on the discovery and the elucidation of the mode of action of several natural and natural-based products as anticancer drugs. After acquisition of new skills in natural products isolation and structure elucidation at the Fundacíon MEDINA (Granada, Spain),

I joined the Schmidt-Dannert lab in October 2016 as Postdoctoral Research Associate. My research project aims to screen and isolate new antifungal compounds from Basidiomycota.

Education/Academic qualification

PhD, Universite de Lorraine

Sep 1 2009Dec 20 2013

Award Date: Dec 20 2013

Masters, Universite de Strasbourg

Sep 1 2007Jun 30 2009

Award Date: Jun 30 2009

Bachelors, Universite Louis Pasteur

Sep 1 2004Jun 30 2007

Award Date: Jun 30 2007

External Positions

Chemist in Natural Products Chemistry, Fundación MEDINA

Nov 3 2014Jan 29 2015

PhD Student, Recherches Scientifiques Luxembourg asbl

Sep 1 2009Dec 20 2013

Research interests

  • Natural Products
  • Drug Discovery

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Research Output

  • 5 Article
  • 5 Review article
  • 1 Editorial
  • 1 Other contribution

Coffee provides a natural multitarget pharmacopeia against the hallmarks of cancer

Gaascht, F., Dicato, M. & Diederich, M., Nov 1 2015, In : Genes and Nutrition. p. 1-17 17 p.

Research output: Contribution to journalReview article

  • 29 Scopus citations

    Novel inhibitors of human histone deacetylases: Design, synthesis and bioactivity of 3-alkenoylcoumarines

    Seidel, C., Schnekenburger, M., Zwergel, C., Gaascht, F., Mai, A., Dicato, M., Kirsch, G., Valente, S. & Diederich, M., Aug 15 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 16, p. 3797-3801 5 p.

    Research output: Contribution to journalArticle

  • 23 Scopus citations

    Plumbagin modulates leukemia cell redox status

    Gaascht, F., Teiten, M. H., Cerella, C., Dicato, M., Bagrel, D. & Diederich, M., 2014, In : Molecules. 19, 7, p. 10011-10032 22 p.

    Research output: Contribution to journalArticle

  • 21 Scopus citations

    Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions

    Teiten, M. H., Gaascht, F., Dicato, M. & Diederich, M., 2013, In : Biochemical Pharmacology. p. 1239-1247 9 p.

    Research output: Contribution to journalReview article

  • 43 Scopus citations

    Découverte, identification et caractérisation de molécules d'origine naturelle capables de cibler les voies de transduction, de prolifération, d'inflammation et de mort cellulaire dans des cellules cancéreuses

    Translated title of the contribution: Discovery, identification and characterization of natural origins molecules capable of targeting transduction, proliferation inflammation pathways and cell death in cancer cellsGaascht, F., Dec 20 2013

    Research output: Other contribution

    Open Access
    File
  • Press / Media

    Mushrooms: The Pharmaceuticals of the Future

    Francois Gaascht

    4/3/17

    1 item of Media coverage

    Press/Media: Expert Comment

    Fellowships, Honors, and Prizes

    European Doctorate

    Francois Gaascht (Recipient), Dec 20 2013

    Prize: Prize (including medals and awards)