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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 2 Similar Profiles
Ligands Medicine & Life Sciences
Opioid Analgesics Medicine & Life Sciences
Antipyrine Medicine & Life Sciences
Indoles Medicine & Life Sciences
Metabotropic Glutamate 5 Receptor Medicine & Life Sciences
beta-Lactams Medicine & Life Sciences
Oxymorphone Medicine & Life Sciences
Cholecystokinin Receptors Medicine & Life Sciences

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Projects 2011 2016

Research Output 1979 2017

1 Citations

Bivalent ligand that activates mu opioid receptor and antagonizes mGluR5 receptor reduces neuropathic pain in mice

Peterson, C. D., Kitto, K. F., Akgün, E., Lunzer, M. M., Riedl, M. S., Vulchanova, L., Wilcox, G. L., Portoghese, P. S. & Fairbanks, C. A. Jan 1 2017 In : Pain. 158, 12, p. 2431-2441 11 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Oxymorphone
mu Opioid Receptor
Neuralgia
Chronic Pain
2 Citations

Heteromer Induction: An Approach to Unique Pharmacology?

Portoghese, P. S., Akgün, E. & Lunzer, M. M. Mar 15 2017 In : ACS Chemical Neuroscience. 8, 3, p. 426-428 3 p.

Research output: Contribution to journalArticle

Pharmacology
Ligands
Opioid Receptors
Opioid Analgesics
14 Citations

Inhibition of inflammatory and neuropathic pain by targeting a Mu opioid receptor/chemokine receptor5 heteromer (MOR-CCR5)

Akgün, E., Javed, M. I., Lunzer, M. M., Powers, M. D., Sham, Y. Y., Watanabe, Y. & Portoghese, P. S. Nov 12 2015 In : Journal of Medicinal Chemistry. 58, 21, p. 8647-8657 11 p.

Research output: Contribution to journalArticle

mu Opioid Receptor
Neuralgia
Chemokines
Chronic Pain
Morphine
19 Citations
Metabotropic Glutamate 5 Receptor
Bone Neoplasms
Opioid Analgesics
Nociception
Hyperalgesia
37 Citations

Bivalent ligands that target μ opioid (MOP) and cannabinoid1 (CB 1) receptors are potent analgesics devoid of tolerance

Le Naour, M., Akgün, E., Yekkirala, A., Lunzer, M. M., Powers, M. D., Kalyuzhny, A. E. & Portoghese, P. S. Jul 11 2013 In : Journal of Medicinal Chemistry. 56, 13, p. 5505-5513 9 p.

Research output: Contribution to journalArticle

Opioid Analgesics
Analgesics
Ligands
Nociception
HEK293 Cells