1979 …2019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 2 Similar Profiles
Opioid Analgesics Medicine & Life Sciences
Ligands Medicine & Life Sciences
mu Opioid Receptor Medicine & Life Sciences
Opioid Receptors Medicine & Life Sciences
Cholecystokinin Receptors Medicine & Life Sciences
Indoles Medicine & Life Sciences
Analgesics Medicine & Life Sciences
Morphine Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2011 2016

Research Output 1979 2019

Combination of a δ-opioid Receptor Agonist and Loperamide Produces Peripherally-mediated Analgesic Synergy in Mice

Bruce, D. J., Peterson, C. D., Kitto, K. F., Akgün, E., Lazzaroni, S., Portoghese, P. S., Fairbanks, C. A. & Wilcox, G. L., Sep 1 2019, In : Anesthesiology. 131, 3, p. 649-663 15 p.

Research output: Contribution to journalArticle

Loperamide
Opioid Receptors
Analgesics
Opioid Analgesics
Analgesia
2 Citations (Scopus)

Combined Glia Inhibition and Opioid Receptor Agonism Afford Highly Potent Analgesics without Tolerance

Akgun, E., Lunzer, M. M. & Portoghese, P. S., Apr 17 2019, In : ACS Chemical Neuroscience. 10, 4, p. 2004-2011 8 p.

Research output: Contribution to journalArticle

Opioid Receptors
Neuroglia
Astrocytes
Neurons
Analgesics

Targeting MOR-mGluR5 heteromers reduces bone cancer pain by activating MOR and inhibiting mGluR5

Shueb, S. S., Erb, S. J., Lunzer, M. M., Speltz, R., Harding-Rose, C., Akgün, E., Simone, D. A. & Portoghese, P. S., Dec 1 2019, In : Neuropharmacology. 160, 107690.

Research output: Contribution to journalArticle

Bone Neoplasms
Opioid Analgesics
Calcaneus
Inbred C3H Mouse
Fibrosarcoma

The bivalent ligand MCC22 potently attenuates hyperalgesia in a mouse model of cisplatin-evoked neuropathic pain without tolerance or reward

Cataldo, G., Erb, S. J., Lunzer, M. M., Luong, N., Akgün, E., Portoghese, P. S., Olson, J. K. & Simone, D. A., Nov 1 2019, In : Neuropharmacology. 158, 107598.

Research output: Contribution to journalArticle

Hyperalgesia
Neuralgia
Peripheral Nervous System Diseases
Reward
Cisplatin
2 Citations (Scopus)
Open Access
mu Opioid Receptor
Arthritis
Opioid Analgesics
Pain
Morphine