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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Muscarinic Receptors Medicine & Life Sciences
Muscarinic M1 Receptors Medicine & Life Sciences
xanomeline Medicine & Life Sciences
Carbachol Medicine & Life Sciences
N-Methylscopolamine Medicine & Life Sciences
Muscarinic M2 Receptors Medicine & Life Sciences
Cyclic GMP Medicine & Life Sciences
Neuroblastoma Medicine & Life Sciences

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Projects 1995 2023

Research Output 1979 2019

Applications and limitations of fitting of the operational model to determine relative efficacies of agonists

Jakubík, J., Randáková, A., Rudajev, V., Zimčík, P., El-Fakahany, E. E. & Doležal, V., Mar 15 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Muscarinic M4 Receptors
Muscarinic M2 Receptors
Protein Subunits
GTP-Binding Proteins
Theoretical Models

Role of membrane cholesterol in differential sensitivity of muscarinic receptor subtypes to persistently bound xanomeline

Randáková, A., Dolejší, E., Rudajev, V., Zimčík, P., Doležal, V., El-Fakahany, E. E. & Jakubík, J., May 1 2018, In : Neuropharmacology. 133, p. 129-144 16 p.

Research output: Contribution to journalArticle

xanomeline
Muscarinic Receptors
Cholesterol
Membranes
Isoleucine
2 Citations (Scopus)

Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors

Jakubík, J., Randáková, A., Zimčík, P., El-Fakahany, E. E. & Doležal, V., Jan 16 2017, In : Scientific Reports. 7, 40381.

Research output: Contribution to journalArticle

N-Methylscopolamine
Muscarinic Receptors
Allosteric Site
Binding Sites
Quinuclidinyl Benzilate
1 Citation (Scopus)

Allosteric modulation of muscarinic receptors

Jakubik, J. & El-Fakahany, E. E., Jan 1 2016, In : Neuromethods. 107, p. 95-130 36 p.

Research output: Contribution to journalArticle

Muscarinic Receptors
Modulation
Ligands
Modulators
G-Protein-Coupled Receptors
1 Citation (Scopus)

Radioligand binding at muscarinic receptors

El-Fakahany, E. E. & Jakubik, J., Jan 1 2016, In : Neuromethods. 107, p. 37-68 32 p.

Research output: Contribution to journalArticle

Muscarinic Receptors
Cholinergic Agents
Ligands
Tissue
Physiology