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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 10 Similar Profiles
Facioscapulohumeral Muscular Dystrophy Medicine & Life Sciences
Myoblasts Medicine & Life Sciences
Muscle Development Medicine & Life Sciences
Transcriptional Activation Medicine & Life Sciences
Genes Chemical Compounds
Homeodomain Proteins Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
DNA Medicine & Life Sciences

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Research Output 2013 2019

A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death

Bosnakovski, D., da Silva, M. T., Sunny, S. T., Ener, E. T., Toso, E. A., Yuan, C., Cui, Z., Walters, M. A., Jadhav, A. & Kyba, M., Sep 11 2019, In : Science advances. 5, 9, eaaw7781.

Research output: Contribution to journalArticle

Open Access
acetylation
gene expression
death
inhibitors
animal models
2 Citations (Scopus)

Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA

Lee, J. K., Bosnakovski, D., Toso, E. A., Dinh, T., Banerjee, S., Bohl, T. E., Shi, K., Orellana, K., Kyba, M. & Aihara, H., Dec 11 2018, In : Cell reports. 25, 11, p. 2955-2962.e3

Research output: Contribution to journalArticle

Facioscapulohumeral Muscular Dystrophy
Primates
Crystal structure
DNA
arginine glutamate
1 Citation (Scopus)

Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression

Bosnakovski, D., Gearhart, M. D., Toso, E. A., Ener, E. T., Choi, S. H. & Kyba, M., Dec 1 2018, In : Scientific reports. 8, 1, 16957.

Research output: Contribution to journalArticle

Open Access
Muscle Development
Gene Expression
Myoblasts
Facioscapulohumeral Muscular Dystrophy
Genes
20 Citations (Scopus)

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction

Park, J-M., Seo, M., Jung, C. H., Grunwald, D., Stone, M., Otto, N. M., Toso, E., Ahn, Y., Kyba, M., Griffin, T. J., Higgins, L. & Kim, D-H., Apr 3 2018, In : Autophagy. 14, 4, p. 584-597 14 p.

Research output: Contribution to journalArticle

Open Access
Autophagy
Phosphotransferases
Phosphorylation
Starvation
Amino Acids
3 Citations (Scopus)

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy

Bosnakovski, D., Gearhart, M. D., Toso, E. A., Recht, O. O., Cucak, A., Jain, A. K., Barton, M. C. & Kyba, M., Oct 1 2017, In : DMM Disease Models and Mechanisms. 10, 10, p. 1211-1216 6 p.

Research output: Contribution to journalArticle

Open Access
Facioscapulohumeral Muscular Dystrophy
Pathology
Animals
Animal Models
Genes