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Research Output 1984 2020

2002
12 Citations (Scopus)

Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element

Braastad, C. D., Leguia, M. & Hendrickson, E. A., Apr 15 2002, In : Nucleic acids research. 30, 8, p. 1713-1724 12 p.

Research output: Contribution to journalArticle

CpG Islands
Autoantigens
Response Elements
Proteins
Deoxyribonuclease I
135 Citations (Scopus)

Ku86 is essential in human somatic cells

Li, G., Nelsen, C. & Hendrickson, E. A., Jan 22 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 2, p. 832-837 6 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Polyploidy
Masks
Ionizing Radiation
Cell Division
206 Citations (Scopus)

Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin

Han, Z., Wei, W., Dunaway, S., Darnowski, J. W., Calabresi, P., Sedivy, J., Hendrickson, E. A., Balan, K. V., Pantazis, P. & Wyche, J. H., May 10 2002, In : Journal of Biological Chemistry. 277, 19, p. 17154-17160 7 p.

Research output: Contribution to journalArticle

HCT116 Cells
Camptothecin
Colonic Neoplasms
Cells
Apoptosis
2001
40 Citations (Scopus)

A Fas-associated Death Domain Protein-dependent Mechanism Mediates the Apoptotic Action of Non-steroidal Anti-inflammatory Drugs in the Human Leukemic Jurkat Cell Line

Han, Z., Pantazis, P., Wyche, J. H., Kouttab, N., Kidd, V. J. & Hendrickson, E. A., Oct 19 2001, In : Journal of Biological Chemistry. 276, 42, p. 38748-38754 7 p.

Research output: Contribution to journalArticle

Fas-Associated Death Domain Protein
Jurkat Cells
Colonic Neoplasms
Anti-Inflammatory Agents
Cells
2000
14 Citations (Scopus)

A new X-ray sensitive CHO cell mutant of ionizing radiation group 7, XR- C2, that is defective in DSB repair but has only a mild defect in V(D)J recombination

Errami, A., Overkamp, W. J. I., He, D. M., Friedl, A. A., Gell, D. A., Eckardt-Schupp, F., Jackson, S. P., Hendrickson, E. A., Lohman, P. H. M. & Zdzienicka, M. Z., Sep 15 2000, In : Mutation Research - DNA Repair. 461, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

V(D)J Recombination
Ionizing radiation
Cricetulus
Ionizing Radiation
DNA-Activated Protein Kinase
3 Citations (Scopus)

Susceptibility to apoptosis is restored in human leukemia HCW-2 cells following induction and stabilization of the apoptotic effector Bak

Chatterjee, D., Pantazis, P., Li, G., Bremner, T. A., Hendrickson, E. A. & Wyche, J. H., Aug 24 2000, In : Oncogene. 19, 36, p. 4108-4116 9 p.

Research output: Contribution to journalArticle

Leukemia
Apoptosis
Staurosporine
Tetradecanoylphorbol Acetate
Cytochromes c
36 Citations (Scopus)

The staurosporine analog, Ro-31-8220, induces apoptosis independently of its ability to inhibit protein kinase C

Han, Z., Pantazis, P., Lange, T. S., Wyche, J. H. & Hendrickson, E. A., Jun 2000, In : Cell Death and Differentiation. 7, 6, p. 521-530 10 p.

Research output: Contribution to journalArticle

Staurosporine
Protein Kinase C
Apoptosis
HL-60 Cells
Cell Proliferation
1999
61 Citations (Scopus)

Cif (cytochrome c efflux-inducing factor) activity is regulated by Bcl- 2 and caspases and correlates with the activation of bid

Han, Z., Bhalla, K., Pantazis, P., Hendrickson, E. A. & Wyche, J. H., Feb 1999, In : Molecular and cellular biology. 19, 2, p. 1381-1389 9 p.

Research output: Contribution to journalArticle

Caspase 2
Cytochromes c
HL-60 Cells
Caspases
Caspase 8
1998
26 Citations (Scopus)

A cytosolic factor is required for mitochondrial cytochrome c efflux during apoptosis

Han, Z., Li, G., Bremner, T. A., Lange, T. S., Zhang, G., Jemmerson, R., Wyche, J. H. & Hendrickson, E. A., Jun 1998, In : Cell Death and Differentiation. 5, 6, p. 469-479 11 p.

Research output: Contribution to journalArticle

Cytochromes c
Apoptosis
Caspase 3
Staurosporine
HL-60 Cells
66 Citations (Scopus)

Identification of two domains of the p70 Ku protein mediating dimerization with p80 and DNA binding

Wang, J., Dong, X., Myung, K., Hendrickson, E. A. & Reeves, W. H., Jan 9 1998, In : Journal of Biological Chemistry. 273, 2, p. 842-848 7 p.

Research output: Contribution to journalArticle

Protein Multimerization
Dimerization
DNA
Proteins
DNA-Activated Protein Kinase
37 Citations (Scopus)

KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia mutated-dependent fashion

Myung, K., Braastad, C., He, D. M. & Hendrickson, E. A., Jun 23 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 13, p. 7664-7669 6 p.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
Autoantigens
DNA Damage
Proteins
DNA-Activated Protein Kinase
53 Citations (Scopus)

XR-C1,a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation

Errami, A., He, D. M., Friedl, A. A., Overkamp, W. J. I., Morolli, B., Hendrickson, E. A., Eckardt-Schupp, F., Oshimura, M., Lohman, P. H. M., Jackson, S. P. & Zdzienicka, M. Z., Jul 1 1998, In : Nucleic acids research. 26, 13, p. 3146-3153 8 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
V(D)J Recombination
CHO Cells
Joints
DNA
1997
203 Citations (Scopus)

A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro

Han, Z., Hendrickson, E. A., Bremner, T. A. & Wyche, J. H., May 16 1997, In : Journal of Biological Chemistry. 272, 20, p. 13432-13436 5 p.

Research output: Contribution to journalArticle

Caspase 3
Peptide Hydrolases
Amino Acids
Aldehydes
Peptides
70 Citations (Scopus)

Cell-cycle regulation of mammalian DNA double-strand-break repair

Hendrickson, E. A., Oct 1997, In : American Journal of Human Genetics. 61, 4, p. 795-800 6 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Cell Cycle
202 Citations (Scopus)

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle

Lee, S. E., Mitchell, R. A., Cheng, A. & Hendrickson, E. A., Mar 1997, In : Molecular and Cellular Biology. 17, 3, p. 1425-1433 9 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Double-Stranded DNA Breaks
Cell Cycle
Severe Combined Immunodeficiency
G2 Phase
41 Citations (Scopus)

KARP-1: A novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity

Myung, K., He, D. M., Lee, S. E. & Hendrickson, E. A., Jun 2 1997, In : EMBO Journal. 16, 11, p. 3172-3184 13 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Leucine Zippers
Autoantigens
Proteins
Double-Stranded DNA Breaks
33 Citations (Scopus)

Monocytic differentiation of HL-60 promyelocytic leukemia cells correlates with the induction of Bcl-x(L)

Chatterjee, D., Han, Z., Mendoza, J., Goodglick, L., Hendrickson, E. A., Pantazis, P. & Wyche, J. H., Oct 1 1997, In : Cell Growth and Differentiation. 8, 10, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

Dimethyl Sulfoxide
HL-60 Cells
Leukemia
Apoptosis
Acids
1996
48 Citations (Scopus)

Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity

Han, Z., Johnston, C., Reeves, W. H., Carter, T., Wyche, J. H. & Hendrickson, E. A., Jun 25 1996, In : Journal of Biological Chemistry. 271, 24, p. 14098-14104 7 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
HL-60 Cells
Electrophoretic Mobility Shift Assay
Double-Stranded DNA Breaks
DNA
6 Citations (Scopus)
V(D)J Recombination
Double-Stranded DNA Breaks
Cricetulus
X-Rays
Cell Line
121 Citations (Scopus)

DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease

Han, Z., Malik, N., Carter, T., Reeves, W. H., Wyche, J. H. & Hendrickson, E. A., Oct 15 1996, In : Journal of Biological Chemistry. 271, 40, p. 25035-25040 6 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Peptide Hydrolases
Proteolysis
DNA
Staurosporine
77 Citations (Scopus)

Isolation and characterization of an apoptosis-resistant variant of human leukemia HL-60 cells that has switched expression from Bcl-2 to Bcl-XL 1

Han, Z., Chatterjee, D., Early, J., Pantazis, P., Hendrickson, E. A. & Wyche, J. H., Apr 1 1996, In : Cancer Research. 56, 7, p. 1621-1628 8 p.

Research output: Contribution to journalArticle

HL-60 Cells
Leukemia
Apoptosis
Suppressor Genes
bcl-2-Associated X Protein
150 Citations (Scopus)

Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants

Errami, A., Smider, V., Rathmell, W. K., He, D. M., Hendrickson, E. A., Zdzienicka, M. Z. & Chu, G., Apr 1996, In : Molecular and cellular biology. 16, 4, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

V(D)J Recombination
Cricetinae
X-Rays
DNA
Double-Stranded DNA Breaks
28 Citations (Scopus)
V(D)J Recombination
Etoposide
Cricetulus
Cricetinae
Restoration
1995
133 Citations (Scopus)

Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen

Boubnov, N. V., Hall, K. T., Wills, Z., Lee, S. E., He, D. M., Benjamin, D. M., Pulaski, C. R., Band, H., Reeves, W., Hendrickson, E. A. & Weaver, D. T., Jan 31 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 3, p. 890-894 5 p.

Research output: Contribution to journalArticle

Radiation Tolerance
Ionizing Radiation
Genetic Recombination
DNA
Genes
103 Citations (Scopus)

Evidence for a G2 checkpoint in p53-independent apoptosis induction by X-irradiation

Han, Z., Chatterjee, D., He, D. M., Early, J., Pantazis, P., Wyche, J. H. & Hendrickson, E. A., Nov 1995, In : Molecular and Cellular Biology. 15, 11, p. 5849-5857 9 p.

Research output: Contribution to journalArticle

Apoptosis
Cell Line
HL-60 Cells
DNA Damage
p53 Genes
56 Citations (Scopus)

Isolation of mammalian cell mutants that are X-ray sensitive, impaired in DNA double-strand break repair and defective for V(D)J recombination

Lee, S. E., Pulaski, C. R., He, D. M., Benjamin, D. M., Voss, M., Um, J. & Hendrickson, E. A., May 1995, In : Mutation Research-DNA Repair. 336, 3, p. 279-291 13 p.

Research output: Contribution to journalArticle

V(D)J Recombination
Double-Stranded DNA Breaks
Cell Separation
Repair
Cells
1994
28 Citations (Scopus)

Gene mutation and V(D)J recombination in the radiosensitive irs lines

Thacker, J., Ganesh, A. N., Stretch, A., Benjamin, D. M., Zahalsky, A. J. & Hendrickson, E. A., Mar 1994, In : Mutagenesis. 9, 2, p. 163-168 6 p.

Research output: Contribution to journalArticle

V(D)J Recombination
Repair
Genes
Mutation
X-Rays
1993
55 Citations (Scopus)

The SCID mouse: Relevance as an animal model system for studying human disease

Hendrickson, E. A., Dec 1 1993, In : American Journal of Pathology. 143, 6, p. 1511-1522 12 p.

Research output: Contribution to journalArticle

Animal Models
Immune System Diseases
Immune System
Hope
Mutation
1991
274 Citations (Scopus)

A link between double-strand break-related repair and V(D)J recombination: The scid mutation

Hendrickson, E. A., Qin, X. Q., Bump, E. A., Schatz, D. G., Oettinger, M. & Weaver, D. T., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 10, p. 4061-4065 5 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Genetic Recombination
Mutation
DNA Repair
Hypersensitivity
24 Citations (Scopus)

Strand breaks without DNA rearrangement in V(D)J recombination

Hendrickson, E. A., Liu, V. F. & Weaver, D. T., Jan 1 1991, In : Molecular and cellular biology. 11, 6, p. 3155-3162 8 p.

Research output: Contribution to journalArticle

V(D)J Recombination
Gene Rearrangement
Protein Sorting Signals
Severe Combined Immunodeficiency
B-Lymphoid Precursor Cells
1990
36 Citations (Scopus)

Wild-type V(D)J recombination in scid Pre-B cells

Hendrickson, E. A., Schlissel, M. S. & Weaver, D. T., Jan 1 1990, In : Molecular and cellular biology. 10, 10, p. 5397-5407 11 p.

Research output: Contribution to journalArticle

V(D)J Recombination
B-Lymphoid Precursor Cells
Clone Cells
Immunoglobulins
Mutation
1989
6 Citations (Scopus)

The scid mutation disrupts gene rearrangement at the rejoining of coding strands.

Weaver, D. & Hendrickson, E., Jan 1 1989, In : Current Topics in Microbiology and Immunology. 152, p. 77-84 8 p.

Research output: Contribution to journalArticle

B-Lymphocyte Gene Rearrangement
Immunologic Deficiency Syndromes
Mutant Strains Mice
Gene Rearrangement
Genetic Recombination
1988
65 Citations (Scopus)

The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement.

Hendrickson, E. A., Schatz, D. G. & Weaver, D. T., Jul 1988, In : Genes & development. 2, 7, p. 817-829 13 p.

Research output: Contribution to journalArticle

Immunoglobulin Genes
Trans-Activators
Gene Rearrangement
Genetic Recombination
B-Lymphoid Precursor Cells
1987
7 Citations (Scopus)

Polyoma virus DNA replication is semi-discontinuous

Hendrickson, E. A., Fritze, C. E., R.folk, W. & Depamphilis, M. L., Aug 25 1987, In : Nucleic acids research. 15, 16, p. 6369-6385 17 p.

Research output: Contribution to journalArticle

Polyomavirus
Virus Replication
Simian virus 40
DNA Replication
DNA
29 Citations (Scopus)

The origin of bidirectional DNA replication in polyoma virus.

Hendrickson, E. A., Fritze, C. E., Folk, W. R. & DePamphilis, M. L., Jul 1987, In : The EMBO journal. 6, 7, p. 2011-2018 8 p.

Research output: Contribution to journalArticle

Polyomavirus
DNA Replication
Viruses
Replication Origin
DNA
1985
41 Citations (Scopus)

DNA primase-DNA polymerase α from simian cells: Sequence specificity of initiation sites on simian virus 40 DNA

Yamaguchi, M., Hendrickson, E. A. & DePamphilis, M. L., Dec 1 1985, In : Molecular and cellular biology. 5, 5, p. 1170-1183 14 p.

Research output: Contribution to journalArticle

DNA Primase
Simian virus 40
DNA-Directed DNA Polymerase
DNA
Ribonucleosides
40 Citations (Scopus)

DNA primase-DNA polymerase α from simian cells. Modulation of RNA primer synthesis by ribonucleoside triphosphates

Yamaguchi, M., Hendrickson, E. A. & DePamphilis, M. L., Jan 1 1985, In : Journal of Biological Chemistry. 260, 10, p. 6254-6263 10 p.

Research output: Contribution to journalArticle

DNA Primase
Ribonucleosides
DNA-Directed DNA Polymerase
Modulation
DNA
1984
40 Citations (Scopus)

Sequence specificity for the initiation of RNA-primed simian virus 40 DNA synthesis in vivo

Hay, R. T., Hendrickson, E. A. & DePamphilis, M. L., May 15 1984, In : Journal of Molecular Biology. 175, 2, p. 131-157 27 p.

Research output: Contribution to journalArticle

Simian virus 40
RNA
DNA
DNA Primase
Genome