Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Nucleus accumbens fast-spiking interneurons regulate opioid reward and addiction- R00
Lefevre, E. (PI)
NATIONAL INSTITUTES OF HEALTH (NIH)
3/1/24 → 2/28/25
Project: Research project
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Fentanyl-evoked gene expression changes in reward circuitry with single cell and spatial specificity
Lefevre, E. (PI)
BRAIN & BEHAVIOR RESEARCH FOUNDATION
1/15/23 → 1/14/25
Project: Research project
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Nucleus accumbens fast-spiking interneurons regulate opioid reward and addiction
Lefevre, E. (PI)
3/1/22 → 2/29/24
Project: Research project
Research output
- 9 Article
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Differential Patterns of Synaptic Plasticity in the Nucleus Accumbens Caused by Continuous and Interrupted Morphine Exposure
Lefevre, E. M., Gauthier, E. A., Bystrom, L. L., Scheunemann, J. & Rothwell, P. E., Jan 11 2023, In: Journal of Neuroscience. 43, 2, p. 308-318 11 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Angiotensin-converting enzyme gates brain circuit–specific plasticity via an endogenous opioid
Trieu, B. H., Remmers, B. C., Toddes, C., Brandner, D. D., Lefevre, E. M., Kocharian, A., Retzlaff, C. L., Dick, R. M., Mashal, M. A., Gauthier, E. A., Xie, W., Zhang, Y., More, S. S. & Rothwell, P. E., Mar 11 2022, In: Science. 375, 6585, p. 1177-1182 6 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
μ-opioid receptor (oprm1) copy number influences nucleus accumbens microcircuitry and reciprocal social behaviors
Toddes, C., Lefevre, E. M., Brandner, D. D., Zugschwert, L. & Rothwell, P. E., Sep 22 2021, In: Journal of Neuroscience. 41, 38, p. 7965-7977 13 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Interruption of continuous opioid exposure exacerbates drug-evoked adaptations in the mesolimbic dopamine system
Lefevre, E. M., Pisansky, M. T., Toddes, C., Baruffaldi, F., Pravetoni, M., Tian, L., Kono, T. J. Y. & Rothwell, P. E., Oct 1 2020, In: Neuropsychopharmacology. 45, 11, p. 1781-1792 12 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats
Lefevre, E., Gooch, H., Josh, P., Alexander, S., Eyles, D. W. & Burne, T. H. J., Aug 1 2019, In: Behavioural Pharmacology. 30, 5, p. 383-395 13 p.Research output: Contribution to journal › Article › peer-review