Projects per year
Personal profile
Research interests
I am a physician-scientist with a strong interest and a translational approach to investigation of solid tumor malignancies at the cellular and molecular level. As a fellowship-trained and practicing medical oncologist and neuro-oncologist, I have a strong interest in a ‘bedside-to-bench-and-back’ approach to translational oncology and laboratory research. At the national level, I served on the American Society of Clinical Oncology (ASCO) Scientific Committee for GI Cancers (2012-15). Identifying pertinent clinical problems in oncology that can be investigated in the laboratory setting is a high priority for our research program and collaborative efforts. I am board-certified in medical oncology, neuro-oncology, and internal medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- intercellular communication
- cancer
- tumor microenvironment
- cancer cell biology
- tunneling nanotubes
- tumor genomics
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Network
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Leveraging low oxygen environments for improved Natural Killer cell immunotherapy
Kennedy, P., Felices, M., Lou, E., Luo, X. & Miller, J. S.
5/1/21 → 10/31/23
Project: Research project
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ERBB family fusions are recurrent and actionable oncogenic targets across cancer types
Schubert, L., Elliott, A., Le, A. T., Estrada-Bernal, A., Doebele, R. C., Lou, E., Borghaei, H., Demeure, M. J., Kurzrock, R., Reuss, J. E., Ou, S. H. I., Braxton, D. R., Thomas, C. A., Darabi, S., Korn, W. M., El-Deiry, W. S. & Liu, S. V., 2023, In: Frontiers in Oncology. 13, 1115405.Research output: Contribution to journal › Article › peer-review
Open Access -
Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study
Wang, J., Xiu, J., Farrell, A., Baca, Y., Arai, H., Battaglin, F., Kawanishi, N., Soni, S., Zhang, W., Millstein, J., Shields, A. F., Grothey, A., Weinberg, B. A., Marshall, J. L., Lou, E., Khushman, M., Sohal, D. P. S., Hall, M. J., Liu, T., Oberley, M., & 4 others , Feb 2023, In: The Lancet Oncology. 24, 2, p. 151-161 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer
Seeber, A., Battaglin, F., Zimmer, K., Kocher, F., Baca, Y., Xiu, J., Spizzo, G., Novotny-Diermayr, V., Rieder, D., Puccini, A., Swensen, J., Ellis, M., Goldberg, R. M., Grothey, A., Shields, A. F., Marshall, J. L., Weinberg, B. A., Sackstein, P. E., Lim, K. H., Tan, G. S., & 8 others , May 1 2022, In: Clinical Cancer Research. 28, 9, p. 1863-1870 8 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Erratum: Molecular alterations associated with improved outcome in patients with glioblastoma treated with Tumor-Treating Fields (Neuro-Oncology Advances (2022) 4:1 (vdac096) DOI: 10.1093/noajnl/vdac096)
Pandey, M., Xiu, J., Mittal, S., Zeng, J., Saul, M., Kesari, S., Azadi, A., Newton, H., Deniz, K., Ladner, K., Sumrall, A., Korn, W. M. & Lou, E., Jan 1 2022, In: Neuro-Oncology Advances. 4, 1, vdac164.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Genomic characterization of undifferentiated sarcomatoid carcinoma of the pancreas
Gkountakos, A., Mafficini, A., Lou, E., Malleo, G., Salvia, R., Calicchia, M., Silvestris, N., Racila, E., Amin, K., Veronese, N., Brunetti, O., Antonini, P., Ingravallo, G., Mattiolo, P., Saponaro, C., Nappo, F., Simbolo, M., Bariani, E., Lonardi, S., Fassan, M., & 4 others , Oct 2022, In: Human pathology. 128, p. 124-133 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Datasets
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Perceptions of COVID-19 and Health Survey in the United States, Cross-sectional study April 2020
Vogel, R., Lou, E., Mburu, W., Thomaier, L., Hui, J., Nelson, H. H., Teoh, D. G., Brown, K., Blaes, A. H., Holtan, S. G., Jewett, P. I. & Parsons, H. M., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/fxwc-np62, http://hdl.handle.net/11299/216556
Dataset
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COVID-19 Concerns among Physicians who treat cancer survey in the United States, Cross-sectional study March/April 2020
Vogel, R., Thomaier, L., Lou, E., Teoh, D. G., Jewett, P. I., Beckwith, H. C., Parsons, H. M., Yuan, J., Blaes, A. H. & Hui, J., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/bmsy-hb61, http://hdl.handle.net/11299/216451
Dataset
Press/Media
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6 Colon Cancer Symptoms That Are Easily Overlooked
5/8/20
1 item of Media coverage
Press/Media: Expert Comment or Interview