Projects per year
Personal profile
Research interests
I am a physician-scientist with a strong interest and a translational approach to investigation of solid tumor malignancies at the cellular and molecular level. As a fellowship-trained and practicing medical oncologist and neuro-oncologist, I have a strong interest in a ‘bedside-to-bench-and-back’ approach to translational oncology and laboratory research. At the national level, I served on the American Society of Clinical Oncology (ASCO) Scientific Committee for GI Cancers (2012-15). Identifying pertinent clinical problems in oncology that can be investigated in the laboratory setting is a high priority for our research program and collaborative efforts. I am board-certified in medical oncology, neuro-oncology, and internal medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- intercellular communication
- cancer
- tumor microenvironment
- cancer cell biology
- tunneling nanotubes
- tumor genomics
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Collaborations and top research areas from the last five years
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Elucidating the role of ovarian tumor cell networking in spatial architecture and tumor heterogeneity and implications for chemoresistance
Lou, E. (PI)
7/1/22 → 6/30/26
Project: Research project
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Multi-Omics data for Cancer Research and the Development of New Diagnostics and Therapies
Lou, E. (PI)
9/9/20 → 9/30/25
Project: Research project
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University of Minnesota Clinical Center for the Study of Pancreatic Disease
Bellin, M. D. (PI), Armfield, M. A. (CoI), Chinnakotla, S. (CoI), Freeman, M. L. (CoI), Lou, E. (CoI), Schwarzenberg, S. J. (CoI), Spilseth, B. D. (CoI) & Trikudanathan, G. V. (CoI)
NIH NATL INST OF DIABETES/DIG/KIDNEY DIS
9/3/20 → 6/30/25
Project: Research project
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Comprehensive characterization of MCL-1 in patients with colorectal cancer: Expression, molecular profiles, and outcomes
Mittal, P., Battaglin, F., Baca, Y., Xiu, J., Farrell, A., Soni, S., Lo, J. H., Torres-Gonzalez, L., Algaze, S., Jayachandran, P., Ashouri, K., Wong, A., Zhang, W., Yu, J., Zhang, L., Weinberg, B. A., Lou, E., Shields, A. F., Goldberg, R. M. & Marshall, J. L. & 3 others, , Apr 15 2025, In: International Journal of Cancer. 156, 8, p. 1583-1593 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cracking the code for more effective treatments for hepatocellular carcinomas: Promise and a path for immunovirotherapy
Lou, E., Mar 20 2025, In: Molecular Therapy Oncology. 33, 1, 200955.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Ardalan, B., Ciner, A., Baca, Y., Hinton, A., Darabi, S., Kasi, A., Lou, E., Azqueta, J. I., Xiu, J., Datta, J., Shields, A. F., Aguirre, A., Singh, H., Shroff, R. T., Pishvaian, M. J. & Goel, S., Mar 15 2025, In: Clinical Cancer Research. 31, 6, p. 1082-1090 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Early Circulating Tumor DNA Kinetics as a Dynamic Biomarker of Cancer Treatment Response
Li, A., Lou, E., Leder, K. & Foo, J. Y., Mar 1 2025, In: JCO Clinical Cancer Informatics. 9, p. e2400160Research output: Contribution to journal › Article › peer-review
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Evidence for Unified Assessment Criteria of HER2 Immunohistochemistry in Colorectal Carcinoma
Evans, M. G., Krause, H. B., Xiu, J., Elliott, A., Lou, E., Ghani, H., Yantiss, R. K., Garcia-Buitrago, M., Matsubara, Y., Nakamura, Y., Shia, J., Yaeger, R., Radovich, M., Bryant, D. A., Oberley, M. J. & Hechtman, J. F., Feb 2025, In: Modern Pathology. 38, 2, 100654.Research output: Contribution to journal › Article › peer-review
Datasets
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Perceptions of COVID-19 and Health Survey in the United States, Cross-sectional study April 2020
Vogel, R. I., Lou, E., Mburu, W., Thomaier, L., Hui, J., Nelson, H. H., Teoh, D. G., Brown, K., Blaes, A. H., Holtan, S. G., Jewett, P. I. & Parsons, H. M., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/fxwc-np62, http://hdl.handle.net/11299/216556
Dataset
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COVID-19 Concerns among Physicians who treat cancer survey in the United States, Cross-sectional study March/April 2020
Vogel, R. I., Thomaier, L., Lou, E., Teoh, D. G., Jewett, P. I., Beckwith, H. C., Parsons, H. M., Yuan, J., Blaes, A. H. & Hui, J., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/bmsy-hb61, http://hdl.handle.net/11299/216451
Dataset
Press/Media
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6 Colon Cancer Symptoms That Are Easily Overlooked
5/8/20
1 item of Media coverage
Press/Media: Expert Comment or Interview