Emil Lou

Physician-Scientist, Assistant Professor

Accepting PhD Students

20012020

Research output per year

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Personal profile

Research interests

I am a physician-scientist with a strong interest and a translational approach to investigation of solid tumor malignancies at the cellular and molecular level. As a fellowship-trained and practicing medical oncologist and neuro-oncologist, I have a strong interest in a ‘bedside-to-bench-and-back’ approach to translational oncology and laboratory research. At the national level, I served on the American Society of Clinical Oncology (ASCO) Scientific Committee for GI Cancers (2012-15). Identifying pertinent clinical problems in oncology that can be investigated in the laboratory setting is a high priority for our research program and collaborative efforts. I am board-certified in medical oncology, neuro-oncology, and internal medicine.

Research interests

  • intercellular communication
  • cancer
  • tumor microenvironment
  • cancer cell biology

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects

Research Output

Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today

Sperduto, P. W., Mesko, S., Li, J., Cagney, D., Aizer, A., Lin, N. U., Nesbit, E., Kruser, T. J., Chan, J., Braunstein, S., Lee, J., Kirkpatrick, J. P., Breen, W., Brown, P. D., Shi, D., Shih, H. A., Soliman, H., Sahgal, A., Shanley, R., Sperduto, W. & 19 others, Lou, E., Everett, A., Boggs, D. H., Masucci, L., Roberge, D., Remick, J., Plichta, K., Buatti, J. M., Jain, S., Gaspar, L. E., Wu, C. C., Wang, T. J. C., Bryant, J., Chuong, M., Yu, J., Chiang, V., Nakano, T., Aoyama, H. & Mehta, M. P., 2020, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

  • 2 Scopus citations

    Changing Oncology Treatment Paradigms in the COVID-19 Pandemic

    Lou, E. & Subramanian, S., 2020, (Accepted/In press) In : Clinical Colorectal Cancer.

    Research output: Contribution to journalComment/debate

    Open Access

    Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors

    Zhao, X., Kassaye, B., Wangmo, D., Lou, E. & Subramanian, S., May 22 2020, In : iScience. 23, 5, 101056.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Locally Advanced Rectal Cancer - Precision Therapy in a Time of Moving Targets and Competing Goals

    Madoff, R. D. & Lou, E., 2020, (Accepted/In press) In : JAMA Oncology.

    Research output: Contribution to journalComment/debate

    RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling

    Nelson, A. C., Turbyville, T. J., Dharmaiah, S., Rigby, M., Yang, R., Wang, T-Y., Columbus, J., Stephens, R., Taylor, T., Sciacca, D., Onsongo, G., Sarver, A., Subramanian, S., Nissley, D. V., Simanshu, D. K. & Lou, E., Jul 10 2020, In : The Journal of biological chemistry. 295, 28, p. 9335-9348 14 p.

    Research output: Contribution to journalArticle

  • Press / Media

    6 Colon Cancer Symptoms That Are Easily Overlooked

    Emil Lou

    5/8/20

    1 item of Media coverage

    Press/Media: Expert Comment

    Answering common questions about colorectal cancer

    Emil Lou

    3/10/20

    2 items of Media coverage

    Press/Media: Expert Comment

    Talking colorectal cancer with the U of M

    Emil Lou

    3/3/20

    1 item of Media coverage

    Press/Media: Expert Comment