Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 7 Finished
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Chemical Methods to Characterize Penicillin-Binding Protein Function and Interactions
Carlson, E. E. (PI) & Ambrose, E. A. (CoI)
NIH NIGMS NATL INST OF GENERAL
9/18/20 → 6/30/24
Project: Research project
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Spaciotemporal Regulation of Specific Penicillin Binding Protein (PBP) Function Determined by New Activity-Based Approaches
Carlson, E. E. (PI) & Ambrose, E. A. (CoI)
NIH NIGMS NATL INST OF GENERAL
9/1/18 → 8/31/20
Project: Research project
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Chemical Biology Consortium, Task Order #1
Georg, G. (PI), Ambrose, E. A. (CoI), Gurvich, V. J. (CoI), Hook, D. (CoI) & Walters, M. A. (CoI)
LEIDOS BIOMEDICAL RESEARCH, INC., NIH NATIONAL CANCER INSTITUTE (NCI)
10/10/09 → 1/11/10
Project: Research project
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Anthrax Toxin Lethal Factor Inhibition Study
Ambrose, E. A. (PI), Finzel, B. C. (CoI), Hook, D. (CoI), Johnson, R. L. (CoI) & Walters, M. A. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
7/6/09 → 6/30/15
Project: Research project
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Chemically Controlled Assembly of Therapeutic Protein Na
Wagner, C. R. (PI), Ambrose, E. A. (CoI), Vallera, D. A. (CoI), Lodge, T. (Other Role), Siegel, R. A. (Other Role) & Truhlar, D. G. (Other Role)
NIH NATIONAL CANCER INSTITUTE (NCI)
9/21/07 → 7/31/11
Project: Research project
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Chemical Transformation of B- to A-type Proanthocyanidins and 3D Structural Implications
Jing, S. X., McDermott, C. M., Flanders, P. L., Reis-Havlat, M., Chen, S. N., Bedran-Russo, A. K., McAlpine, J. B., Ambrose, E. A. & Pauli, G. F., May 24 2024, In: Journal of Natural Products. 87, 5, p. 1416-1425 10 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Combined Structural Analysis and Molecular Dynamics Reveal Penicillin-Binding Protein Inhibition Mode with β-Lactones
Flanders, P. L., Contreras-Martel, C., Brown, N. W., Shirley, J. D., Martins, A., Nauta, K. N., Dessen, A., Carlson, E. E. & Ambrose, E. A., Nov 18 2022, In: ACS Chemical Biology. 17, 11, p. 3110-3120 11 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
7-methylation of chenodeoxycholic acid derivatives yields a substantial increase in TGR5 receptor potency
Nakhi, A., Mcdermott, C. M., Stoltz, K. L., John, K., Hawkinson, J. E., Ambrose, E. A., Khoruts, A., Sadowsky, M. J. & Dosa, P. I., Jul 25 2019, In: Journal of medicinal chemistry. 62, 14, p. 6824-6830 7 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Botulinum neurotoxin, tetanus toxin, and anthrax lethal factor countermeasures
Ambrose, E. A., Jul 1 2017, Topics in Medicinal Chemistry. Springer Verlag, p. 47-67 21 p. (Topics in Medicinal Chemistry; vol. 22).Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
Erratum: Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria (Cell Chemical Biology (2017) 24(10) (1259–1275.e6) (S2451945617302830)(10.1016/j.chembiol.2017.08.009))
Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F. & Norris, B. & 17 others, , Oct 19 2017, In: Cell Chemical Biology. 24, 10, p. 1314 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access7 Scopus citations