Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Identifying Histone H3.3 phospho-Serine 31 readers in diffuse midline glioma cells
Hinchcliffe, E. H. (PI) & Langfald, A. K. (Other Role)
9/1/25 → 8/31/27
Project: Research project
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Hepatic Stellate Cell Regulation of Metastatic Growth in the Liver
Kang, N. (PI), Bai, B. (Other Role), Hinchcliffe, E. H. (Other Role) & Wang, L. (Other Role)
8/1/22 → 7/31/26
Project: Research project
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Defining the relative contribution of K27 methylation and S31 phosphorylation to gliomagenesis in DIPG
Hinchcliffe, E. H. (PI) & Robinson, J. (PI)
9/1/22 → 8/31/25
Project: Research project
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Targeting Chromosome Instability and the cGAS-STING Network in Pediatric Mid-Line Gliomas - K27M Mutant
Hinchcliffe, E. H. (PI) & Robinson, J. (PI)
9/1/21 → 8/31/24
Project: Research project
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Working towards targeted therapy in H3K27M tumors: Aurora Kinase Inhibitors and the role of epigenome programing
Hinchcliffe, E. H. (PI) & Day, C. A. (CoI)
MAYO CLINIC ROCHESTER, NATIONAL INSTITUTES OF HEALTH (NIH)
9/1/20 → 5/31/25
Project: Research project
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H3F3A K27M mutations drive a repressive transcriptome by modulating chromatin accessibility independent of H3K27me3 in Diffuse Midline Glioma
Bhattarai, S., Hakkim, F. L., Day, C. A., Grigore, F., Langfald, A., Entin, I., Hinchcliffe, E. H. & Robinson, J. P., Dec 2025, In: Epigenetics and Chromatin. 18, 1, 23.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
Day, C. A., Grigore, F., Hakkim, F. L., Paul, S., Langfald, A., Weberg, M., Fadness, S., Schwab, P., Sepaniac, L., Stumpff, J., Vaughan, K. T., Daniels, D. J., Robinson, J. P. & Hinchcliffe, E. H., Jan 20 2025, In: Current Biology. 35, 2, p. 354-362.e7Research output: Contribution to journal › Article › peer-review
5 Link opens in a new tab Scopus citations -
Overcoming translational barriers in H3K27-altered diffuse midline glioma: Increasing the drug-tumor residence time
Power, E. A., Rechberger, J. S., Zhang, L., Oh, J. H., Anderson, J. B., Nesvick, C. L., Ge, J., Hinchcliffe, E. H., Elmquist, W. F. & Daniels, D. J., Jan 1 2023, In: Neuro-Oncology Advances. 5, 1Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations -
StARD9 is a novel lysosomal kinesin required for membrane tubulation, cholesterol transport and Purkinje cell survival
Sterling, F. R., D’Amico, J., Brumfield, A. M., Huegel, K. L., Vaughan, P. S., Morris, K., Schwarz, S., Joyce, M. V., Boggess, B., Champion, M. M., Maciuba, K., Allen, P., Marasco, E., Koch, G., Gonzalez, P., Hodges, S., Leahy, S., Gerstbauer, E., Hinchcliffe, E. H. & Vaughan, K. T., Mar 2023, In: Journal of cell science. 136, 5, jcs260662.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
H3K27me3 in Diffuse Midline Glioma and Epithelial Ovarian Cancer: Opposing Epigenetic Changes Leading to the Same Poor Outcomes
Day, C. A., Hinchcliffe, E. H. & Robinson, J. P., Nov 2022, In: Cells. 11, 21, 3376.Research output: Contribution to journal › Review article › peer-review
Open Access20 Link opens in a new tab Scopus citations
Press/Media
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Institute Scientists Receive Award for Pediatric Brain Tumor Research
Hinchcliffe, E. H., Day, C. A. & Robinson, J.
10/21/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
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Letter: This is how we fight back
7/22/20
1 Media contribution
Press/Media: Expert Comment or Interview
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A collaboration between The Hormel Institute and Mayo Clinic is looking to find treatment of brain cancer in children
Hinchcliffe, E. H. & Robinson, J.
2/18/20
1 item of Media coverage
Press/Media: Research