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Edward H Hinchcliffe

19972020
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Projects 2009 2020

Cellular mechanisms underlying pediatric glioblastoma: Heterozygous mutations in histone H3.3 induce chromosome instability by abolishing Ser31 phosphorylation

Hinchcliffe, E. H.

U.S. DEPARTMENT OF DEFENSE

9/1/18 → 8/31/20

Project: Research project

Chromosomal Instability
Glioblastoma
Histones
Phosphorylation
Pediatrics

The functional role of the cPLA2alpha/CIP interaction in

Hinchcliffe, E. H.

University of South Florida

2/12/18 → 5/31/20

Project: Research project

Sepsis

The functional role of the cPLA2alpha/C1P interaction in

Hinchcliffe, E. H.

Virginia Commonwealth University

9/15/14 → 9/30/17

Project: Research project

Sepsis

Defects in Histone H3.3 phosphorylation, and ATRX recrui

Hinchcliffe, E. H.

US DEPT OF DEFENSE ARMY

9/1/14 → 8/31/17

Project: Research project

Glioblastoma
Mitosis
Histones
Chromosomes
Phosphorylation

Mechanisms of centrosome reproduction in animal cells

Hinchcliffe, E. H.

NIH NIGMS NATL INST OF GENERAL

1/1/09 → 8/31/12

Project: Research project

Research Output 1997 2019

Characterization of Novel Murine and Human PDAC Cell Models: Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression

Ganaie, A. A., Parray, A., Hussain, T., Shabaneh, A., Jamroze, A., Ferrari, M. G., Wang, L., Liao, D. J., Koocheckpour, S., Nanda, S., Wang, J., Deng, Y., Gradilone, S., Hinchcliffe, E. H., Konety, B. R. & Bhat, M. S., Aug 1 2019, In : Translational Oncology. 12, 8, p. 1056-1071 16 p.

Research output: Contribution to journal › Article

Open Access
Homeobox Genes
Intestines
Disease Progression
Neoplasms
Aurora Kinases

CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation

Mishra, S. K., Gao, Y-G., Deng, Y., Chalfant, C. E., Hinchcliffe, E. H. & Brown, R. E., May 4 2018, In : Autophagy. 14, 5

Research output: Contribution to journal › Article

Microsurgery and microinjection techniques in mitosis research

Day, C. A., Hornick, J., Langfald, A., Mader, C. & Hinchcliffe, E. H., Jan 1 2018, Methods in Cell Biology. Maiato, H. & Schuh, M. (eds.). Academic Press Inc., p. 159-172 14 p. (Methods in Cell Biology; vol. 145).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Microsurgery
Microinjections
Mitosis
Micromanipulation
Cell Division

Cytoplasmic dynein during mitosis

Hinchcliffe, E. H. & Vaughan, K. T., Nov 22 2017, Dyneins: The Biology of Dynein Motors: Second Edition. Elsevier Inc., p. 535-555 21 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Cytoplasmic Dyneins
Microtubule Proteins
Mitosis
M Phase Cell Cycle Checkpoints
Dyneins
32 Citations (Scopus)

Chromosome missegregation during anaphase triggers p53 cell cycle arrest through histone H3.3 Ser31 phosphorylation

Hinchcliffe, E. H., Day, C. A., Karanjeet, K. B., Fadness, S., Langfald, A., Vaughan, K. T. & Dong, Z., Jun 1 2016, In : Nature Cell Biology. 18, 6, p. 668-675 8 p.

Research output: Contribution to journal › Article

Anaphase
Cell Cycle Checkpoints
Histones
Chromosomes
Phosphorylation