Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Control of Chromosome Segregation by DNA Topoisomerase II
Clarke, D. J. (PI) & Lama, B. (Other Role)
NIH NIGMS NATL INST OF GENERAL
4/1/24 → 2/29/28
Project: Research project
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A high-throughput screen for inhibitors of Plk1-interacting checkpoint helicase (PICH)
Clarke, D. J. (PI)
2/1/22 → 1/31/25
Project: Research project
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Control of Chromosome Segregation by DNA Topoisomerase II
Clarke, D. J. (PI)
NIH NIGMS NATL INST OF GENERAL
3/1/19 → 12/31/23
Project: Research project
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Regulation of kinetochore function by Topoisomerase II
Clarke, D. J. (PI)
KU CENTER FOR RESEARCH, INC., NIH NIGMS NATL INST OF GENERAL
1/12/15 → 12/31/18
Project: Research project
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SUMOylation of Topoisomerase II Critical for Centromere
Clarke, D. J. (PI)
3/1/10 → 2/28/12
Project: Research project
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Histone H3 N-Terminal Tail Residues Important for Meiosis in Saccharomyces cerevisiae
Prichard, A., Johansson, M., Kirkpatrick, D. T. & Clarke, D. J., Aug 2025, In: Biomolecules. 15, 8, 1202.Research output: Contribution to journal › Article › peer-review
Open Access -
PICH impacts the spindle assembly checkpoint via its DNA translocase and SUMO-interaction activities
Lama, B., Park, H., Saraf, A., Hassebroek, V., Keifenheim, D., Saito-Fujita, T., Saitoh, N., Aksenova, V., Arnaoutov, A., Dasso, M., Clarke, D. J. & Azuma, Y., Apr 2025, In: Life science alliance. 8, 4, e202403140.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell cycle responses to Topoisomerase II inhibition: Molecular mechanisms and clinical implications
Soliman, T. N., Keifenheim, D., Parker, P. J. & Clarke, D. J., Dec 4 2023, In: Journal of Cell Biology. 222, 12, e202209125.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations -
Low tension recruits the yeast Aurora B protein Ipl1 to centromeres in metaphase
Edgerton, H. D., Mukherjee, S. R., Johansson, M. R., Bachant, J., Gardner, M. K. & Clarke, D. J., Aug 2023, In: Journal of cell science. 136, 16, jcs261416.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Methylated histones on mitotic chromosomes promote topoisomerase IIα function for high fidelity chromosome segregation
Sundararajan, S., Park, H., Kawano, S., Johansson, M. R., Lama, B., Saito-Fujita, T., Saitoh, N., Arnaoutov, A., Dasso, M., Wang, Z., Keifenheim, D., Clarke, D. J. & Azuma, Y., May 19 2023, In: iScience. 26, 5, 106743.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations