Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 9 Similar Profiles
Type II DNA Topoisomerase Medicine & Life Sciences
Mitosis Medicine & Life Sciences
Anaphase Medicine & Life Sciences
Chromatids Medicine & Life Sciences
Chromosomes Medicine & Life Sciences
Saccharomycetales Medicine & Life Sciences
Cell Cycle Medicine & Life Sciences
S Phase Cell Cycle Checkpoints Medicine & Life Sciences

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Projects 2003 2018

DNA topoisomerase (ATP-hydrolysing)
kinetochores
Chromosomes
Yeasts
interphase
yeasts

Research Output 1993 2018

Analyzing mitotic chromosome structural defects after topoisomerase II inhibition or mutation

Giménez-Abián, J. F., Lane, A. B. & Clarke, D. J. Jan 1 2018 Methods in Molecular Biology. Humana Press Inc., Vol. 1703, p. 191-215 25 p. (Methods in Molecular Biology; vol. 1703)

Research output: Chapter in Book/Report/Conference proceedingChapter

Type II DNA Topoisomerase
Chromosomes
Mutation
Topoisomerase II Inhibitors
Cell Cycle

Monitoring the DNA topoisomerase II checkpoint in Saccharomyces cerevisiae

Furniss, K., Vas, A. C. J., Lane, A. B. & Clarke, D. J. Jan 1 2018 Methods in Molecular Biology. Humana Press Inc., Vol. 1703, p. 217-240 24 p. (Methods in Molecular Biology; vol. 1703)

Research output: Chapter in Book/Report/Conference proceedingChapter

Type II DNA Topoisomerase
Genomic Instability
Catenated DNA
Saccharomyces cerevisiae
Cell Cycle

Cell surface damage activates a cell cycle checkpoint (comment on DOI: 10.1002/bies.201600210)

Clarke, D. J. Apr 1 2017 In : BioEssays. 39, 4, 1700022

Research output: Contribution to journalComment/debate

Cell Cycle Checkpoints

MCPH1, mutated in primary microcephaly, is required for efficient chromosome alignment during mitosis

Arroyo, M., Kuriyama, R., Trimborn, M., Keifenheim, D., Cañuelo, A., Sánchez, A., Clarke, D. J. & Marchal, J. A. Dec 1 2017 In : Scientific Reports. 7, 1, 13019

Research output: Contribution to journalArticle

Microcephaly
Mitosis
Chromosomes
Cell Cycle
G2 Phase
2 Citations

Non-catalytic roles of the topoisomerase IIα C-terminal domain

Clarke, D. J. & Azuma, Y. Nov 17 2017 In : International Journal of Molecular Sciences. 18, 11, 2438

Research output: Contribution to journalReview article

DNA
Enzymes
strands
helices
Type I DNA Topoisomerase