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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Control of Chromosome Segregation by DNA Topoisomerase II
Clarke, D. J. (PI)
NIH NIGMS NATL INST OF GENERAL
4/1/24 → 3/31/29
Project: Research project
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A high-throughput screen for inhibitors of Plk1-interacting checkpoint helicase (PICH)
Clarke, D. J. (PI)
NIH NATIONAL CANCER INSTITUTE (NCI)
2/1/22 → 1/31/25
Project: Research project
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Control of Chromosome Segregation by DNA Topoisomerase II
Clarke, D. J. (PI)
NIH NIGMS NATL INST OF GENERAL
3/1/19 → 12/31/23
Project: Research project
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Regulation of kinetochore function by Topoisomerase II
Clarke, D. J. (PI)
KU CENTER FOR RESEARCH, INC., NIH NIGMS NATL INST OF GENERAL
1/12/15 → 12/31/18
Project: Research project
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SUMOylation of Topoisomerase II Critical for Centromere
Clarke, D. J. (PI)
3/1/10 → 2/28/12
Project: Research project
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PICH impacts the spindle assembly checkpoint via its DNA translocase and SUMO-interaction activities
Lama, B., Park, H., Saraf, A., Hassebroek, V., Keifenheim, D., Saito-Fujita, T., Saitoh, N., Aksenova, V., Arnaoutov, A., Dasso, M., Clarke, D. J. & Azuma, Y., Apr 2025, In: Life science alliance. 8, 4, e202403140.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell cycle responses to Topoisomerase II inhibition: Molecular mechanisms and clinical implications
Soliman, T. N., Keifenheim, D., Parker, P. J. & Clarke, D. J., Dec 4 2023, In: Journal of Cell Biology. 222, 12, e202209125.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
Low tension recruits the yeast Aurora B protein Ipl1 to centromeres in metaphase
Edgerton, H. D., Mukherjee, S. R., Johansson, M. R., Bachant, J., Gardner, M. K. & Clarke, D. J., Aug 2023, In: Journal of cell science. 136, 16, jcs261416.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Methylated histones on mitotic chromosomes promote topoisomerase IIα function for high fidelity chromosome segregation
Sundararajan, S., Park, H., Kawano, S., Johansson, M. R., Lama, B., Saito-Fujita, T., Saitoh, N., Arnaoutov, A., Dasso, M., Wang, Z., Keifenheim, D., Clarke, D. J. & Azuma, Y., May 19 2023, In: iScience. 26, 5, 106743.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase
Parmar, S., Gonzalez, S. J., Heckel, J. M., Mukherjee, S., McClellan, M., Clarke, D. J., Johansson, M., Tank, D., Geisness, A., Wood, D. K. & Gardner, M. K., Aug 7 2023, In: Journal of Cell Biology. 222, 8, e202202085.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations