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  • 2024

    A paradigm shift: AMPK negatively regulates ULK1 activity

    Park, J. M. & Kim, D. H., 2024, In: Autophagy. 20, 4, p. 960-962 3 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Contrasting views on the role of AMPK in autophagy

    Kim, D. H., Mar 2024, In: BioEssays. 46, 3, 2300211.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • ULK1 seen at the single-molecule level during autophagy initiation

    Banerjee, C., Puchner, E. M. & Kim, D. H., 2024, In: Autophagy. 20, 3, p. 707-708 2 p.

    Research output: Contribution to journalArticlepeer-review

  • 2023

    Redefining the role of AMPK in autophagy and the energy stress response

    Park, J. M., Lee, D. H. & Kim, D. H., Dec 2023, In: Nature communications. 14, 1, 2994.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    41 Scopus citations
  • ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation

    Banerjee, C., Mehra, D., Song, D., Mancebo, A., Park, J. M., Kim, D. H. & Puchner, E. M., 2023, In: Science Advances. 9, 39, eadh4094.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • 2021

    Defective autophagy and increased apoptosis contribute toward the pathogenesis of FKRP-associated muscular dystrophies

    Ortiz Cordero, C., Bincoletto, C., Dhoke, N., Selvaraj, S., Magli, A., Zhou, H., Kim, D. H., Bang, A. G. & Perlingeiro, R. C. R., Nov 9 2021, In: Stem Cell Reports. 16, 11, p. 2752-2767 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • 2020

    A Novel Mechanism for NF-kB-activation via IkB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation

    Liu, Y., Trnka, M. J., Guan, S., Kwon, D., Kim, D. H., Chen, J. J., Greer, P. A., Burlingame, A. L. & Correia, M. A., Dec 1 2020, In: Molecular and Cellular Proteomics. 19, 12, p. 1968-1985 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction

    Grunwald, D. S., Otto, N. M., Park, J. M., Song, D. & Kim, D. H., Apr 2 2020, In: Autophagy. 16, 4, p. 600-614 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    67 Scopus citations
  • 2019

    Unconventional secretion of adipocyte fatty acid binding protein 4 is mediated by autophagic proteins in a sirtuin-1-dependent manner

    Josephrajan, A., Hertzel, A. V., Bohm, E. K., McBurney, M. W., Imai, S. I., Mashek, D. G., Kim, D. H. & Bernlohr, D. A., Sep 1 2019, In: Diabetes. 68, 9, p. 1767-1777 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    36 Scopus citations
  • 2018

    ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction

    Park, J. M., Seo, M., Jung, C. H., Grunwald, D., Stone, M., Otto, N. M., Toso, E., Ahn, Y., Kyba, M., Griffin, T. J., Higgins, L. A. & Kim, D. H., Apr 3 2018, In: Autophagy. 14, 4, p. 584-597 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    123 Scopus citations
  • 2017

    Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2)

    Olson, D. H., Burrill, J. S., Kuzmicic, J., Hahn, W. S., Park, J. M., Kim, D. H. & Bernlohr, D. A., Nov 25 2017, In: Biochemical and Biophysical Research Communications. 493, 3, p. 1311-1317 7 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • N-(1-Benzyl-3,5-dimethyl‑1H‑pyrazol-4-yl)benzamides: Antiproliferative activity and effects on mTORC1 and autophagy

    Ai, T., Willett, R., Williams, J., Ding, R., Wilson, D. J., Xie, J., Kim, D. H., Puertollano, R. & Chen, L., Jan 12 2017, In: ACS Medicinal Chemistry Letters. 8, 1, p. 90-95 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • 2016

    An expanded role for mTORC1 in autophagy

    Kim, Y. M., Park, J. M., Grunwald, D. & Kim, D. H., Jan 2 2016, In: Molecular and Cellular Oncology. 3, 1, e1010958.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    10 Scopus citations
  • mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress

    Yun, Y. S., Kim, K. H., Tschida, B., Sachs, Z., Noble-Orcutt, K. E., Moriarity, B. S., Ai, T., Ding, R., Williams, J., Chen, L., Largaespada, D. & Kim, D. H., Feb 18 2016, In: Molecular Cell. 61, 4, p. 625-639 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14

    Park, J. M., Jung, C. H., Seo, M., Otto, N. M., Grunwald, D., Kim, K. H., Moriarity, B., Kim, Y. M., Starker, C., Nho, R. S., Voytas, D. & Kim, D. H., Apr 5 2016, In: Autophagy. 12, 3, p. 547-564 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    232 Scopus citations
  • Uncoordinated 51-like kinase 2 signaling pathway regulates epithelial-mesenchymal transition in A549 lung cancer cells

    Kim, Y. H., Baek, S. H., Kim, E. K., Ha, J. M., Jin, S. Y., Lee, H. S., Ha, H. K., Song, S. H., Kim, S. J., Shin, H. K., Yong, J., Kim, D. H., Kim, C. D. & Bae, S. S., May 1 2016, In: FEBS Letters. 590, 9, p. 1365-1374 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations
  • 2015

    MRNA 3′-UTR shortening is a molecular signature of mTORC1 activation

    Chang, J. W., Zhang, W., Yeh, H. S., De Jong, E. P., Jun, S., Kim, K. H., Bae, S. S., Beckman, K., Hwang, T. H., Kim, K. S., Kim, D. H., Griffin, T. J., Kuang, R. & Yong, J., Jun 15 2015, In: Nature communications. 6, 7218.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • MTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation

    Kim, Y. M., Jung, C. H., Seo, M., Kim, E. K., Park, J. M., Bae, S. S. & Kim, D. H., Jan 22 2015, In: Molecular Cell. 57, 2, p. 207-218 12 p.

    Research output: Contribution to journalArticlepeer-review

    213 Scopus citations
  • 2013

    Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes

    Ro, S. H., Jung, C. H., Hahn, W. S., Xu, X., Kim, Y. M., Yun, Y. S., Park, J. M., Kim, K. H., Seo, M., Ha, T. Y., Arriaga, E. A., Bernlohr, D. A. & Kim, D. H., Dec 2013, In: Autophagy. 9, 12, p. 2103-2114 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    79 Scopus citations
  • Epigenetic regulation of autophagy by the methyltransferase G9a

    De Narvajas, A. A. M., Gomez, T. S., Zhang, J. S., Mann, A. O., Taoda, Y., Gorman, J. A., Herreros-Villanueva, M., Gress, T. M., Ellenrieder, V., Bujand, L., Kim, D. H., Kozikowski, A. P., Koenig, A. & Billadeau, D. D., 2013, In: Molecular and cellular biology. 33, 20, p. 3983-3993 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    169 Scopus citations
  • 2012

    Crystal structure of the Gtr1pGTP-Gtr2pGDP protein complex reveals large structural rearrangements triggered by GTP-to-GDP conversion

    Jeong, J. H., Lee, K. H., Kim, Y. M., Kim, D. H., Oh, B. H. & Kim, Y. G., Aug 24 2012, In: Journal of Biological Chemistry. 287, 35, p. 29648-29653 6 p.

    Research output: Contribution to journalArticlepeer-review

    55 Scopus citations
  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L. & Alegre-Abarrategui, J. & 1,249 others, Aleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. K., Vaccaro, M. I., Valente, E. M., Van Den Berghe, G., Van Der Klei, I. J., Van Doorn, W. G., Van Dyk, L. F., Van Egmond, M., Van Grunsven, L. A., Vandenabeele, P., Vandenberghe, W. P., Vanhorebeek, I., Vaquero, E. C., Velasco, G., Vellai, T., Vicencio, J. M., Vierstra, R. D., Vila, M., Vindis, C., Viola, G., Viscomi, M. T., Voitsekhovskaja, O. V., Von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C. L., Walsh, C. M., Walter, J., Wan, X. B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H. G., Wang, H. D., Wang, J., Wang, K., Wang, M., Wang, R. C., Wang, X., Wang, X., Wang, Y. J., Wang, Y., Wang, Z., Wang, Z. C., Wang, Z., Wansink, D. G., Ward, D. M., Watada, H., Waters, S. L., Webster, P., Wei, L., Weihl, C. C., Weiss, W. A., Welford, S. M., Wen, L. P., Whitehouse, C. A., Whitton, J. L., Whitworth, A. J., Wileman, T., Wiley, J. W., Wilkinson, S., Willbold, D., Williams, R. L., Williamson, P. R., Wouters, B. G., Wu, C., Wu, D. C., Wu, W. K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In: Autophagy. 8, 4, p. 445-544 100 p.

    Research output: Contribution to journalArticlepeer-review

    2920 Scopus citations
  • SH3BP4 Is a Negative Regulator of Amino Acid-Rag GTPase-mTORC1 Signaling

    Kim, Y. M., Stone, M., Hwang, T. H., Kim, Y. G., Dunlevy, J. R., Griffin, T. J. & Kim, D. H., Jun 29 2012, In: Molecular Cell. 46, 6, p. 833-846 14 p.

    Research output: Contribution to journalArticlepeer-review

    76 Scopus citations
  • 2011

    Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy

    Joo, J. H., Dorsey, F. C., Joshi, A., Hennessy-Walters, K. M., Rose, K. L., McCastlain, K., Zhang, J., Iyengar, R., Jung, C. H., Suen, D. F., Steeves, M. A., Yang, C. Y., Prater, S. M., Kim, D. H., Thompson, C. B., Youle, R. J., Ney, P. A., Cleveland, J. L. & Kundu, M., Aug 19 2011, In: Molecular Cell. 43, 4, p. 572-585 14 p.

    Research output: Contribution to journalArticlepeer-review

    196 Scopus citations
  • ULK1 inhibits the kinase activity of mTORC1 and cell proliferation

    Jung, C. H., Seo, M., Otto, N. M. & Kim, D. H., Oct 2011, In: Autophagy. 7, 10, p. 1212-1221 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    139 Scopus citations
  • 2010

    Cyclic AMP controls mTOR through regulation of the dynamic interaction between Rheb and phosphodiesterase 4D

    Kim, H. W., Ha, S. H., Lee, M. N., Huston, E., Kim, D. H., Jang, S. K., Suh, P. G., Houslay, M. D. & Ryu, S. H., Nov 2010, In: Molecular and cellular biology. 30, 22, p. 5406-5420 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    58 Scopus citations
  • Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response

    Bandhakavi, S., Kim, Y. M., Ro, S. H., Xie, H., Onsongo, G., Jun, C. B., Kim, D. H. & Griffin, T. J., Feb 2010, In: Molecular and Cellular Proteomics. 9, 2, p. 403-414 12 p.

    Research output: Contribution to journalArticlepeer-review

    43 Scopus citations
  • 2009

    Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

    Mi, N. L., Sang, H. H., Kim, J., Koh, A., Chang, S. L., Jung, H. K., Jeon, H., Kim, D. H., Suh, P. G. & Sung, H. R., Jul 2009, In: Molecular and cellular biology. 29, 14, p. 3991-4001 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    155 Scopus citations
  • ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

    Jung, C. H., Jun, C. B., Ro, S. H., Kim, Y. M., Otto, N. M., Cao, J., Kundu, M. & Kim, D. H., Apr 1 2009, In: Molecular biology of the cell. 20, 7, p. 1992-2003 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1668 Scopus citations
  • 2008

    GβL regulates TNFα-induced NF-k{cyrillic}B signaling by directly inhibiting the activation of Ik{cyrillic}B kinase

    Kim, Y. L., Kim, J. E., Shin, K. J., Lee, S., Ahn, C., Chung, J., Kim, D. H., Seong, J. Y. & Hwang, J. I., Nov 1 2008, In: Cellular Signalling. 20, 11, p. 2127-2133 7 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis

    Bandhakavi, S., Xie, H., O'Callaghan, B., Sakurai, H., Kim, D. H. & Griffin, T. J., Feb 13 2008, In: PloS one. 3, 2, e1598.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • 2007

    Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

    Haar, E. V., Lee, S. I., Bandhakavi, S., Griffin, T. J. & Kim, D. H., Mar 2007, In: Nature Cell Biology. 9, 3, p. 316-323 8 p.

    Research output: Contribution to journalArticlepeer-review

    977 Scopus citations
  • PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor β expression and signaling

    Woo, S. Y., Kim, D. H., Jun, C. B., Kim, Y. M., Haar, E. V., Lee, S. I., Hegg, J. W., Bandhakavi, S., Griffin, T. J. & Kim, D. H., Aug 31 2007, In: Journal of Biological Chemistry. 282, 35, p. 25604-25612 9 p.

    Research output: Contribution to journalArticlepeer-review

    172 Scopus citations
  • 2006

    PLD2 forms a functional complex with mTOR/raptor to transduce mitogenic signals

    Ha, S. H., Kim, D. H., Kim, I. S., Kim, J. H., Lee, M. N., Lee, H. J., Kim, J. H., Jang, S. K., Suh, P. G. & Ryu, S. H., Dec 2006, In: Cellular Signalling. 18, 12, p. 2283-2291 9 p.

    Research output: Contribution to journalArticlepeer-review

    50 Scopus citations
  • 2004

    Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

    Dos, D. S., Ali, S. M., Kim, D. H., Guertin, D. A., Latek, R. R., Erdjument-Bromage, H., Tempst, P. & Sabatini, D. M., Jul 27 2004, In: Current Biology. 14, 14, p. 1296-1302 7 p.

    Research output: Contribution to journalArticlepeer-review

    2285 Scopus citations
  • 2003

    Contribution of conserved amino acids at the dimeric interface to the conformational stability and the structural integrity of the active site in ketosteroid isomerase from Pseudomonas putida biotype B

    Nam, G. H., Kim, D. H., Ha, N. C., Jang, D. S., Yun, Y. S., Hong, B. H., Oh, B. H. & Choi, K. Y., Jul 1 2003, In: Journal of Biochemistry. 134, 1, p. 101-110 10 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • GβL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

    Kim, D. H., Sarbassov, D. D., Ali, S. M., Latek, R. R., Guntur, K. V. P., Erdjument-Bromage, H., Tempst, P. & Sabatini, D. M., Apr 1 2003, In: Molecular Cell. 11, 4, p. 895-904 10 p.

    Research output: Contribution to journalArticlepeer-review

    826 Scopus citations
  • 2002

    mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

    Kim, D. H., Sarbassov, D. D., Ali, S. M., King, J. E., Latek, R. R., Erdjument-Bromage, H., Tempst, P. & Sabatini, D. M., Jul 26 2002, In: Cell. 110, 2, p. 163-175 13 p.

    Research output: Contribution to journalArticlepeer-review

    2513 Scopus citations
  • 2001

    15N NMR relaxation studies of backbone dynamics in free and steroid-bound Δ5-3-ketosteroid isomerase from Pseudomonas testosteroni

    Yun, S., Do Soo Jang, S. J., Kim, D. H., Kwan Yong Choi, Y. C. & Hee Cheon Lee, C. L., Apr 3 2001, In: Biochemistry. 40, 13, p. 3967-3973 7 p.

    Research output: Contribution to journalArticlepeer-review

    30 Scopus citations
  • Folding mechanism of ketosteroid isomerase from Comamonas testosteroni

    Kim, D. H., Do So Jang, S. J., Gyu Hyun Nam, H. N. & Kwan Yong Choi, Y. C., Apr 24 2001, In: Biochemistry. 40, 16, p. 5011-5017 7 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Maintenance of α-helical structures by phenyl rings in the active-site tyrosine triad contributes to catalysis and stability of ketosteroid isomerase from Pseudomonas putida biotype B

    Nam, G. H., Jang, D. S., Cha, S. S., Lee, T. H., Kim, D. H., Hong, B. H., Yun, Y. S., Oh, B. H. & Choi, K. Y., Nov 13 2001, In: Biochemistry. 40, 45, p. 13529-13537 9 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Roles of dimerization in folding and stability of ketosteroid isomerase from Pseudomonas putida biotype B

    Kim, D. H., Nam, G. H., Jang, D. S., Yun, S., Choi, G., Lee, H. C. & Choi, K. Y., 2001, In: Protein Science. 10, 4, p. 741-752 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Structural Origin for the Transcriptional Activity of Human p53

    Lee, S. H., Park, K. H., Kim, D. H., Choung, D. H., Suk, J. E., Kim, D. H., Chang, J., Sung, Y. C., Choi, K. Y. & Han, K. H., Jan 31 2001, In: Journal of Biochemistry and Molecular Biology. 34, 1, p. 73-79 7 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • The role of Tyr248 probed by mutant bovine carboxypeptidase A: Insight into the catalytic mechanism of carboxypeptidase A

    Cho, J. H., Kim, D. H., Kim, D. H., Lee, K. J. & Choi, K. Y., Aug 28 2001, In: Biochemistry. 40, 34, p. 10197-10203 7 p.

    Research output: Contribution to journalArticlepeer-review

    40 Scopus citations
  • 2000

    Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of Δ5-3-ketosteroid isomerase from Pseudomonas putida biotype B

    Choi, G., Ha, N. C., Kim, S. W., Kim, D. H., Park, S., Oh, B. H. & Choi, K. Y., Feb 8 2000, In: Biochemistry. 39, 5, p. 903-909 7 p.

    Research output: Contribution to journalArticlepeer-review

    42 Scopus citations
  • Characterization of active-site residues of the NIa protease from tobacco vein mottling virus

    Hwang, D. C., Kim, D. H., Lee, J. S., Kang, B. H., Han, J., Kim, W., Song, B. D. & Choi, K. Y., Oct 31 2000, In: Molecules and cells. 10, 5, p. 505-511 7 p.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations
  • Contribution of the hydrogen-bond network involving a tyro sine triad in the active site to the structure and function of a highly proficient ketosteroid isomerase from Pseudomonas putida biotype B

    Kim, D. H., Jang, D. S., Nam, G. H., Choi, G., Kim, J. S., Ha, N. C., Kim, M. S., Oh, B. H. & Choi, K. Y., Apr 25 2000, In: Biochemistry. 39, 16, p. 4581-4589 9 p.

    Research output: Contribution to journalArticlepeer-review

    43 Scopus citations
  • Equilibrium and kinetic analysis of folding of ketosteroid isomerase from Comamonas testosteroni

    Kim, D. H., Soo Jang, D., Hyun Nam, G., Yun, S., Hyun Cho, J., Choi, G., Cheon Lee, H. & Yong Choi, K., Oct 24 2000, In: Biochemistry. 39, 42, p. 13084-13092 9 p.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Local structural elements in the mostly unstructured transcriptional activation domain of human p53

    Lee, H., Mok, K. H., Muhandiram, R., Park, K. H., Suk, J. E., Kim, D. H., Chang, J., Sung, Y. C., Choi, K. Y. & Han, K. H., Sep 22 2000, In: Journal of Biological Chemistry. 275, 38, p. 29426-29432 7 p.

    Research output: Contribution to journalArticlepeer-review

    297 Scopus citations
  • Molecular cloning, expression, and purification of nuclear inclusion a protease from tobacco vein mottling virus

    Hwang, D. C., Kim, D. H., Kang, B. H., Song, B. D. & Choi, K. Y., Apr 30 2000, In: Molecules and cells. 10, 2, p. 148-155 8 p.

    Research output: Contribution to journalArticlepeer-review

    9 Scopus citations