Projects per year
Personal profile
Research interests
I am interested in developing and understanding the properties of nano/bio-materials and engineering the surface chemistry for various biomedical applications. The primary focus is on engineering polymeric and or metallic/metal oxide nanoparticles, and composites for cancer targeting, drug/molecular delivery, tissue engineering, bone regeneration and dental applications.
Publications
- Methacrylate Polymers with 'Flipped External' Ester Groups: A Review, Dhiraj Kumar, Robert D Bolskar, Isha Mutreja, and Robert S Jones, 2022 (Frontiers in Dental Medicine (IF–), DOI: 10.3389/fdmed.2022.923780).
- Emerging Nanostructures in Dental Applications, Debarati Ghose* and Dhiraj Kumar* 2022 (Book Chapter), DOI: https://link.springer.com/chapter/10.1007/978-981-19-1312-9_8).
- Strontium- and peptide-modified silicate nanostructures for dual osteogenic and antimicrobial activity, Isha Mutreja, Dhiraj Kumar, Kami Hogan, Emily Campbell, Kim Mansky, Conrado Aparicio, 2021 (Biomaterials Advances (IF–7.328), DOI: 10.1016/j.bioadv.2022.212735).
- Utilizing a degradation prediction pathway system to understand how a novel methacrylate derivative polymer with flipped external ester groups retains physico-mechanical properties following esterase exposure, Dhiraj Kumar, Debarati Ghose, Robert D Bolskar, Isha Mutreja, Conrado Aparicio, and Robert S Jones. 2021 (Dental Materials (IF–5.304), DOI: 10.1016/j.dental.2021.12.008).
- Hybrid nanocoatings of antimicrobial peptides and silver nanoparticles for preservation of implant infections, Zhou Ye, Ting Sang, Kun Li, Nicholas G. Fisher, Isha Mutreja, Constanza Echeverria, Dhiraj Kumar, Zhen Tang, Conrado Aparicio. 2021 (Acta Biomaterialia (IF–8.947), DOI: 10.1016/j.actbio.2021.12.008).
- A novel methacrylate derivative polymer that resists bacterial cell-mediated biodegradation, Dhiraj Kumar, Debarati Ghose, Robert D Bolskar, Isha Mutreja, and Robert S Jones. 2021 (Journal of Biomedical Materials Research B (IF–3.368), DOI: 10.1002/jbm.b.34972).
- A novel dental polymer with a flipped external ester group design that resists degradation via polymer backbone preservation, Dhiraj Kumar, Robert D Bolskar, Sydney Malone, Isha Mutreja, Conrado Aparicio, and Robert S Jones. 2020 (ACS, Biomaterials Science & Engineering (IF–4.152), DOI: 10.1021/acsbiomaterials.0c00947).
- Design and characterization of multi-functional strontium-gelatin nanocomposite bioinks with improved print fidelity and osteogenic capacity, Cesar R. Alcala-Orozco, Isha Mutreja, Xiaolin Cui, Dhiraj Kumar, Gary J. Hooper, Khoon S. Lim, Tim B.F. Woodfield. 2020 (Bioprinting (IF – 5.88), DOI: 10.1016/j.bprint.2019.e00073).
- Cancer Imaging with Nanoparticles Using MARS Spectral Scanner, 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC) (DOI: 10.1109/nssmic.2018.8824632).
- Spectral photon-counting molecular imaging for quantification of monoclonal antibody conjugated gold nanoparticles targeted to lymphoma and breast cancer – an in vitro study, M Moghiseh, C Lowe, J G. Lewis, D Kumar, A Butler, N Anderson, and A Raja. 2018 (Contrast Media and Molecular Imaging, Hindawi/Wiley (IF-2.934), DOI: 10.1155/2018/2136840).
- Self-assembly Dynamics and Antimicrobial Activity of all L- and D-amino Acid Enantiomers of a Designer Peptide, Z Ye, X Zhu, S Acosta, D Kumar, T Sang and C Aparicio. 2018 (Nanoscale (IF-7.233), DOI: 10.1039/C8NR07334A).
- Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells, D Kumar, I Mutreja, K Chitcholtan and P Sykes. 2017 (Nanotechnology IOP (IF-3.573), DOI: 10.1088/1361-6528/aa935e).
- Seed mediated synthesis of highly mono-dispersed gold nanoparticles in presence of hydroquinone, D Kumar, I Mutreja and P Sykes. 2016 (Nanotechnology IOP (IF-3.573), DOI: 10.1088/0957-4484/27/35/355601).
- ORMOSIL Nanoparticle Interaction with Macrophage Cells: Assessment of Cell Viability on the Basis of Physico-Chemical Properties of Nanoparticles, D Kumar, I Mutreja, C K Prashant, M Bhat, A K Dinda and S Mitra. 2015 (Journal of Pharmaceutical Sciences (IF-2.85), DOI:1002/jps.24614).
- Current Density Enhancement in Inverted Nano-pyramid Textured Crystalline Silicon Solar Cell using Gold Nanoparticles, S Sivasubramaniam, D Kumar, V B Golovko, and M Alkaisi. 2013 (Micro/Nano Materials, Devices, and Systems, SPIE Proceeding, DOI: 10.1117/12.2033731).
- The profile of payload release from gold nanoparticles modified with a BODIPY®/PEG mixed Monolayer, D Kumar, I Mutreja, BJ Meenan and D Dixon. 2013 (Journal of Nano Research (IF-0.52), DOI: 4028/www.scientific.net/JNanoR.25.16).
- Titania Nanotube Porosity Controls Dissolution Rate of Sputter Deposited Calcium Phosphate (CaP) Thin Film Coatings, I Mutreja, D Kumar, A Boyd and BJ Meenan, 2012. (RSC Advances (IF-3.289), DOI: 1039/C3RA40898A).
- Glutathione Mediated Release of BODIPY from Polyethylene Glycol co-functionalized Gold Nanoparticles, D Kumar, BJ Meenan and D Dixon, 2012 (International Journal of Nanomedicine (IF-4.976), DOI: 10.2147/IJN.S33726).
- Controlling the Size and Size Distribution of Gold Nanoparticles: A Design of Experiment Study, D Kumar, BJ Meenan, I Mutreja, R D’Sa and D Dixon, 2012. (International Journal of Nanoscience (IF-), DOI: 10.1142/S0219581X12500238).
- Polyethylene Glycol Functionalized Gold Nanoparticles: The Influence of capping density on stability in various media. J Manson*, D Kumar* (*Equal contribution), BJ Meenan and D Dixon, 2011. (Gold Bulletin (IF-2.719), DOI: 10.1007/s13404-011-0015-8).
- The loading and release properties of nanoporous anodic alumina for delivery of drugs and drug carriers, M Sinn Aw, S Simovic, D Kumar, J Addai-Mensah, D Losic, 2010. (ICONN 2010, IEEE Xplore, DOI: 10.1109/ICONN.2010.6045213).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Ulster University
Sep 1 2009 → Oct 21 2012
Award Date: May 6 2013
Masters, Amity University
2007 → 2009
MSc, Department of Chemistry, Delhi University
2004 → 2006
BS, Hindu College, Delhi University
2001 → 2004
External Positions
Research Fellow, Department of Obstetrics and Gynecology, University of Otago at Christchurch
Jan 2014 → Jun 2018
Visiting Postdoc, School of Engineering, University of Canterbury
2013 → 2015
Research Interest Keywords
- Nanotherapeutics
- nanoparticle
- biomaterials
- Nanomedicine
- nanomaterials
- nanotechnology
- nanobioengineering
- Polymers
- Drug Delivery
- molecular delivery
- Cancer targeting
- nano-composites
- Nanotheranostics
- Nano-contrast agent
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Network
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Utilizing a degradation prediction pathway system to understand how a novel methacrylate derivative polymer with flipped external ester groups retains physico-mechanical properties following esterase exposure
Kumar, D., Ghose, D., Mutreja, I., Bolskar, R. D., Aparicio, C. & Jones, R. S., Dec 18 2021, In: Dental Materials.Research output: Contribution to journal › Article › peer-review
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Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An In Vitro Study
Moghiseh, M., Lowe, C., Lewis, J. G., Kumar, D., Butler, A., Anderson, N. & Raja, A., Dec 18 2018, In: Contrast Media and Molecular Imaging.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Design and characterisation of multi-functional strontium-gelatin nanocomposite bioinks with improved print fidelity and osteogenic capacity
Alcala-Orozco, C. R., Mutreja, I., Cui, X., Kumar, D., Hooper, G. J., Lim, K. S. & Woodfield, T. B. F., Dec 2019, In: Bioprinting.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells
Kumar, D., Mutreja, I., Chitcholtan, K. & Sykes, P., Nov 3 2017, In: Nanotechnology. 28, 47, 475101.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
A novel methacrylate derivative polymer that resists bacterial cell-mediated biodegradation
Kumar, D., Ghose, D., Bolskar, R. D., Mutreja, I. & Jones, R. S., Dec 2 2021, In: Journal of Biomedical Materials Research - Part B Applied Biomaterials.Research output: Contribution to journal › Article › peer-review
Datasets
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A Novel Methacrylate Derivative Polymer That Resists Bacterial Cell-Mediated Biodegradation Data Sharing Archive
Kumar, D., Ghose, D., Mutreja, I., Bolskar, R. D. & Jones, R. S., Data Repository for the University of Minnesota, Nov 22 2021
DOI: 10.13020/jms8-pq47, https://hdl.handle.net/11299/225348
Dataset
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Investigating the Cytocompatibility of a Novel Flipped Ester Group Design Polymer Composites against Oral Keratinocytes
Kumar, D., Bolskar, R. D., Mutreja, I. & Jones, R. S., Data Repository for the University of Minnesota, May 9 2022
https://hdl.handle.net/11299/227293
Dataset