Dezhi Liao

1992 …2024
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects 2006 2024

AMP-Kinase as a target for neuroprotection in AD

Lee, M. K., Lesne, S. E. & Liao, D.

NIH NAT'L INSTITUTE ON AGING (NIA)

2/15/191/31/24

Project: Research project

Adenylate Kinase
Neuroprotection
Chronic Traumatic Encephalopathy
Tauopathies
In Vitro Techniques
Traumatic Brain Injury

Research Output 1992 2019

Phosphorylation in two discrete tau domains regulates a stepwise process leading to postsynaptic dysfunction

Teravskis, P. J., Oxnard, B. R., Miller, E. C., Kemper, L. J., Ashe, K. H. & Liao, D., Jan 1 2019, In : Journal of Physiology.

Research output: Contribution to journalArticle

Dendritic Spines
Phosphorylation
Cyclin-Dependent Kinase 5
Proline
Glycogen Synthase
1 Citation (Scopus)

Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy

Singh, B., Covelo, A., Martell-Martínez, H., Nanclares, C., Sherman, M. A., Okematti, E., Meints, J., Teravskis, P. J., Gallardo, C., Savonenko, A. V., Benneyworth, M. A., Lesne, S. E., Liao, D., Araque, A. & Lee, M. K., Jan 1 2019, In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Memory Disorders
Transgenic Mice
Lewy Body Disease
Parkinson Disease
Dementia
2 Citations (Scopus)

A53t mutant alpha-synuclein induces tau-dependent postsynaptic impairment independently of neurodegenerative changes

Teravskis, P. J., Covelo, A., Miller, E. C., Singh, B., Martell-Martínez, H. A., Benneyworth, M. A., Gallardo, C., Oxnard, B. R., Araque, A., Lee, M. K. & Liao, D., Nov 7 2018, In : Journal of Neuroscience. 38, 45, p. 9754-9767 14 p.

Research output: Contribution to journalArticle

Synucleins
alpha-Synuclein
Parkinson Disease
Pathology
Glycogen Synthase Kinase 3
27 Citations (Scopus)

Tau acts as a mediator for Alzheimer's disease-related synaptic deficits

Liao, D., Miller, E. C. & Teravskis, P. J., Jan 1 2014, In : European Journal of Neuroscience. 39, 7, p. 1202-1213 12 p.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Pathology
tau Proteins
Neurofibrillary Tangles
45 Citations (Scopus)

Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits

Miller, E. C., Teravskis, P. J., Dummer, B. W., Zhao, X., Huganir, R. L. & Liao, D., Jan 1 2014, In : European Journal of Neuroscience. 39, 7, p. 1214-1224 11 p.

Research output: Contribution to journalArticle

AMPA Receptors
Glutamate Receptors
Dendritic Spines
Calcineurin
Phosphorylation