1991 …2020
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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IGF Type 1 Receptor Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Somatomedins Medicine & Life Sciences
Maltose-Binding Proteins Medicine & Life Sciences
Insulin Receptor Medicine & Life Sciences
Insulin-Like Growth Factor I Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Somatomedin Receptors Medicine & Life Sciences

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Projects 2007 2020

Cancer Stem Cell-Targeted, Silicate Prodrug Nanoparticle

Panyam, J., Hoye, T. R., Sachdev, D. & Macosko, C.

NIH NATL INST OF BIOMEDICAL IM

4/1/1712/31/20

Project: Research project

Silicates
Neoplastic Stem Cells
Prodrugs
Nanoparticles
Recurrence
Breast Neoplasms
Neoplasm Metastasis
Pharmaceutical Preparations
metastasis
quantitative polymerase chain reaction
IGF Type 1 Receptor
Breast Neoplasms
Phenotype
Genes

Research Output 1991 2019

Discovery of HSPG2 (Perlecan) as a Therapeutic Target in Triple Negative Breast Cancer

Kalscheuer, S., Khanna, V., Kim, H., Li, S., Sachdev, D., DeCarlo, A., Yang, D. & Panyam, J., Dec 1 2019, In : Scientific reports. 9, 1, 12492.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Antibodies
Antibody-Dependent Cell Cytotoxicity
Therapeutics
Neoplasms
3 Citations (Scopus)

Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions

Aukes, K., Forsman, C., Brady, N. J., Astleford, K., Blixt, N., Sachdev, D., Jensen, E. D., Mansky, K. & Schwertfeger, K., Oct 1 2017, In : PloS one. 12, 10, e0185736.

Research output: Contribution to journalArticle

Open Access
fibroblast growth factors
osteoclasts
Fibroblast Growth Factors
Osteoclasts
lesions (animal)
9 Citations (Scopus)

EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice

Zelenko, Z., Gallagher, E. J., Antoniou, I. M., Sachdev, D., Nayak, A., Yee, D. & LeRoith, D., Jan 1 2016, In : Endocrine-related cancer. 23, 9, p. 747-758 12 p.

Research output: Contribution to journalArticle

Insulin Receptor
Hyperinsulinism
Neoplasms
Type 2 Diabetes Mellitus
Vascular Endothelial Growth Factor A
25 Citations (Scopus)

IGF1R- and ROR1-Specific CAR T cells as a potential therapy for high risk sarcomas

Huang, X., Park, H., Greene, J., Pao, J., Mulvey, E., Zhou, S. X., Albert, C. M., Moy, F., Sachdev, D., Yee, D., Rader, C., Hamby, C. V., Loeb, D. M., Cairo, M. S. & Zhou, X., Jul 14 2015, In : PloS one. 10, 7, e0133152.

Research output: Contribution to journalArticle

sarcoma
T-Cell Antigen Receptor
Sarcoma
T-lymphocytes
antigens
9 Citations (Scopus)

SWIFT MRI enhances detection of breast cancer metastasis to the lung

Kobayashi, N., Idiyatullin, D. S., Corum, C. A., Weber, J., Garwood, M. & Sachdev, D., May 1 2015, In : Magnetic resonance in medicine. 73, 5, p. 1812-1819 8 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasm Metastasis
Lung
Blood Vessels
Growth and Development