Deborah A Ferrington &ndash; Research Output

2004

Altered proteasome function and subunit composition in aged muscle

Husom, A. D., Peters, E. A., Kolling, E. A., Fugere, N. A., Thompson, L. V. & Ferrington, D. A., Jan 1 2004, In : Archives of Biochemistry and Biophysics. 421, 1, p. 67-76 10 p.

Research output: Contribution to journal › Article

Proteasome Endopeptidase Complex

Muscle

Muscles

Chemical analysis

Muscular Atrophy

93 Citations (Scopus)

Catalytic site-specific inhibition of the 20S proteasome by 4-hydroxynonenal

Ferrington, D. A. & Kapphahn, R. J., Dec 17 2004, In : FEBS Letters. 578, 3, p. 217-223 7 p.

Research output: Contribution to journal › Article

Proteasome Endopeptidase Complex

Catalytic Domain

Chymotrypsin

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

Electrophoresis, Gel, Two-Dimensional

28 Citations (Scopus)

Myofibrillar myosin ATPase activity in hindlimb muscles from young and aged rats

Lowe, D. A., Husom, A. D., Ferrington, D. A. & Thompson, L. V., Sep 1 2004, In : Mechanisms of Ageing and Development. 125, 9, p. 619-627 9 p.

Research output: Contribution to journal › Article

Myosins

Hindlimb

Muscle

Rats

Muscles

2003

53 Citations (Scopus)

Modified αA Crystallin in the Retina: Altered Expression and Truncation with Aging

Kapphahn, R. J., Ethen, C. M., Peters, E. A., Higgins, L. A. & Ferrington, D. A., Dec 30 2003, In : Biochemistry. 42, 51, p. 15310-15325 16 p.

Research output: Contribution to journal › Article

Crystallins

Retina

Aging of materials

Rats

Post Translational Protein Processing

2002

42 Citations (Scopus)

Comparable levels of Ca-ATPase inhibition by phospholamban in slow-twitch skeletal and cardiac sarcoplasmic reticulum

Ferrington, D. A., Yao, Q., Squier, T. C. & Bigelow, D. J., Nov 5 2002, In : Biochemistry. 41, 44, p. 13289-13296 8 p.

Research output: Contribution to journal › Article

Sarcoplasmic Reticulum

Adenosine Triphosphatases

Calcium

Phosphorylation

phospholamban

100 Citations (Scopus)

Covalent modification of epithelial fatty acid-binding protein by 4-hydroxynonenal in vitro and in vivo: Evidence for a role in antioxidant biology

Bennaars-Eiden, A., Higgins, L., Hertzel, A. M., Kapphahn, B., Ferrington, D. A. & Bernlohr, D. A., Dec 27 2002, In : Journal of Biological Chemistry. 277, 52, p. 50693-50702 10 p.

Research output: Contribution to journal › Article

Fatty Acid-Binding Proteins

Antioxidants

Proteins

Lipids

Ionization

91 Citations (Scopus)

Proteasome function and protein oxidation in the aged retina

Louie, J. L., Kapphahn, B. & Ferrington, D. A., Jan 1 2002, In : Experimental Eye Research. 75, 3, p. 271-284 14 p.

Research output: Contribution to journal › Article

Proteasome Endopeptidase Complex

Retina

Proteins

Chymotrypsin

Caseins

2001

17 Citations (Scopus)

Electron paramagnetic resonance: A high-resolution tool for muscle physiology

Thompson, L. V., Lowe, D. A., Ferrington, D. A. & Thomas, D. D., Jan 1 2001, In : Exercise and Sport Sciences Reviews. 29, 1, p. 3-6 4 p.

Research output: Contribution to journal › Article

Electron Spin Resonance Spectroscopy

Muscles

Muscle Relaxation

Myosins

Adenosine Triphosphatases

94 Citations (Scopus)

Selective degradation of oxidized calmodulin by the 20 S proteasome

Ferrington, D. A., Sun, H., Murray, K. K., Costa, J., Williams, T. D., Bigelow, D. J. & Squier, T. C., Jan 12 2001, In : Journal of Biological Chemistry. 276, 2, p. 937-943 7 p.

Research output: Contribution to journal › Article

Proteasome Endopeptidase Complex

Calmodulin

Degradation

Hydrophobicity

Hydrophobic and Hydrophilic Interactions

2000

16 Citations (Scopus)

Closer proximity between opposing domains of vertebrate calmodulin following deletion of Met¹⁴⁵-Lys¹⁴⁸

Yin, D., Sun, H., Ferrington, D. A. & Squier, T. C., Aug 22 2000, In : Biochemistry. 39, 33, p. 10255-10268 14 p.

Research output: Contribution to journal › Article

Calmodulin

Vertebrates

Cell membranes

Adenosine Triphosphatases

Cell Membrane

1999

32 Citations (Scopus)

Age-related chemical modification of the skeletal muscle sarcoplasmic reticulum Ca-ATPase of the rat

Schöneich, C., Viner, R. I., Ferrington, D. A. & Bigelow, D. J., Mar 15 1999, In : Mechanisms of Ageing and Development. 107, 3, p. 221-231 11 p.

Research output: Contribution to journal › Article

Sarcoplasmic Reticulum

Adenosine Triphosphatases

Skeletal Muscle

Peroxynitrous Acid

Protein Isoforms

156 Citations (Scopus)

Diastereoselective reduction of protein-bound methionine sulfoxide by methionine sulfoxide reductase

Sharov, V. S., Ferrington, D. A., Squier, T. C. & Schöneich, C., Jul 23 1999, In : FEBS Letters. 455, 3, p. 247-250 4 p.

Research output: Contribution to journal › Article

Calmodulin

sulfoxide

Proteins

Oxidative stress

Liver

8 Citations (Scopus)

Effects of dietary protein on enzyme activity following exercise- induced muscle injury

Hayward, R., Ferrington, D. A., Kochanowski, L. A., Miller, L. M., Jaworsky, G. M. & Schneider, C. M., Jan 1 1999, In : Medicine and Science in Sports and Exercise. 31, 3, p. 414-420 7 p.

Research output: Contribution to journal › Article

Dietary Proteins

Muscles

Protein-Restricted Diet

Wounds and Injuries

Enzymes

243 Citations (Scopus)

Protein modification during biological aging: Selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca²⁺-ATPase in skeletal muscle

Viner, R. I., Ferrington, D. A., Williams, T. D., Bigelow, D. J. & Schöneich, C., Jun 15 1999, In : Biochemical Journal. 340, 3, p. 657-669 13 p.

Research output: Contribution to journal › Article

Nitration

Calcium-Transporting ATPases

Sarcoplasmic Reticulum

Tyrosine

Muscle

137 Citations (Scopus)

Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase

Sun, H., Gao, J., Ferrington, D. A., Biesiada, H., Williams, T. D. & Squier, T. C., Jan 5 1999, In : Biochemistry. 38, 1, p. 105-112 8 p.

Research output: Contribution to journal › Article

Calmodulin

Cell membranes

Adenosine Triphosphatases

Repair

Cell Membrane

1998

70 Citations (Scopus)

Altered turnover of calcium regulatory proteins of the sarcoplasmic reticulum in aged skeletal muscle

Ferrington, D. A., Krainev, A. G. & Bigelow, D. J., Mar 6 1998, In : Journal of Biological Chemistry. 273, 10, p. 5885-5891 7 p.

Research output: Contribution to journal › Article

Sarcoplasmic Reticulum

Muscle

Skeletal Muscle

Calcium

Leucine

1997

24 Citations (Scopus)

Decreased conformational stability of the sarcoplasmic reticulum Ca- ATPase in aged skeletal muscle

Ferrington, D. A., Jones, T. E., Qin, Z., Miller-Schlyer, M., Squier, T. C. & Bigelow, D. J., Dec 4 1997, In : Biochimica et Biophysica Acta - Biomembranes. 1330, 2, p. 233-247 15 p.

Research output: Contribution to journal › Article

Sarcoplasmic Reticulum

Adenosine Triphosphatases

Muscle

Skeletal Muscle

Muscles

36 Citations (Scopus)

In vivo aging of rat skeletal muscle sarcoplasmic reticulum Ca-ATPase. Chemical analysis and quantitative simulation by exposure to low levels of peroxyl radicals

Viner, R. I., Ferrington, D. A., Aced, G. I., Miller-Schlyer, M., Bigelow, D. J. & Schöneich, C., Oct 23 1997, In : Biochimica et Biophysica Acta - Biomembranes. 1329, 2, p. 321-335 15 p.

Research output: Contribution to journal › Article

Sarcoplasmic Reticulum

Adenosine Triphosphatases

Muscle

Rats

Skeletal Muscle

19 Citations (Scopus)

Protein half-lives of calmodulin and the plasma membrane Ca-ATPase in rat brain

Ferrington, D. A., Chen, X., Krainev, A. G., Michaelis, E. K. & Bigelow, D. J., Aug 8 1997, In : Biochemical and Biophysical Research Communications. 237, 1, p. 163-165 3 p.

Research output: Contribution to journal › Article

Calmodulin

Cell membranes

Leucine

Adenosine Triphosphatases

Rats

5 Citations (Scopus)

Protein half-lives of two subunits of an NMDA receptor-like complex, the 71-kDa glutamate-binding and the 80-kDa CPP-binding protein

Chen, X., Ferrington, D. A., Bigelow, D. J. & Michaelis, E. K., Dec 8 1997, In : Biochemical and Biophysical Research Communications. 241, 1, p. 132-135 4 p.

Research output: Contribution to journal › Article

N-Methyl-D-Aspartate Receptors

Glutamic Acid

Carrier Proteins

Proteins

Radioactivity

1996

104 Citations (Scopus)

Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: A peroxynitrite-mediated process?

Viner, R. I., Ferrington, D. A., Hühmer, A. F. R., Bigelow, D. J. & Schöneich, C., Feb 5 1996, In : FEBS Letters. 379, 3, p. 286-290 5 p.

Research output: Contribution to journal › Article

Peroxynitrous Acid

Nitration

Adenosine Triphosphatases

Muscle

Rats

41 Citations (Scopus)

Activation of the sarcoplasmic reticulum Ca²⁺-ATPase induced by exercise

Ferrington, D. A., Reijneveld, J. C., Bär, P. R. & Bigelow, D. J., Mar 13 1996, In : Biochimica et Biophysica Acta - Biomembranes. 1279, 2, p. 203-213 11 p.

Research output: Contribution to journal › Article

Calcium-Transporting ATPases

Sarcoplasmic Reticulum

Chemical activation

Calcium

Membranes

1995

32 Citations (Scopus)

Adaptive changes in lipid composition of skeletal sarcoplasmic reticulum membranes associated with aging

Krainev, A. G., Ferrington, D. A., Williams, T. D., Squier, T. C. & Bigelow, D. J., May 4 1995, In : BBA - Biomembranes. 1235, 2, p. 406-418 13 p.

Research output: Contribution to journal › Article

Sarcoplasmic Reticulum

Aging of materials

Membranes

Lipids

Calcium-Transporting ATPases

1991

Body Composition And Plasma Lipoprotein Profile Of Male And Female Swimming And Track Athletes

Schneider, C. M., Klish, W. J., Insull, W. & Ferrington, D. A., Oct 1 1991, In : Sports Medicine, Training and Rehabilitation. 3, 1, p. 13-18 6 p.

Research output: Contribution to journal › Article

Body Composition

Athletes

Lipoproteins

Adipose Tissue

Cholesterol