1991 …2023
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Research Output 1991 2019

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1991

Body Composition And Plasma Lipoprotein Profile Of Male And Female Swimming And Track Athletes

Schneider, C. M., Klish, W. J., Insull, W. & Ferrington, D. A., Oct 1 1991, In : Sports Medicine, Training and Rehabilitation. 3, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

Body Composition
Athletes
Lipoproteins
Adipose Tissue
Cholesterol
1995
32 Citations (Scopus)

Adaptive changes in lipid composition of skeletal sarcoplasmic reticulum membranes associated with aging

Krainev, A. G., Ferrington, D. A., Williams, T. D., Squier, T. C. & Bigelow, D. J., May 4 1995, In : BBA - Biomembranes. 1235, 2, p. 406-418 13 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Aging of materials
Membranes
Lipids
Calcium-Transporting ATPases
1996
104 Citations (Scopus)

Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: A peroxynitrite-mediated process?

Viner, R. I., Ferrington, D. A., Hühmer, A. F. R., Bigelow, D. J. & Schöneich, C., Feb 5 1996, In : FEBS Letters. 379, 3, p. 286-290 5 p.

Research output: Contribution to journalArticle

Peroxynitrous Acid
Nitration
Adenosine Triphosphatases
Muscle
Rats
41 Citations (Scopus)

Activation of the sarcoplasmic reticulum Ca2+-ATPase induced by exercise

Ferrington, D. A., Reijneveld, J. C., Bär, P. R. & Bigelow, D. J., Mar 13 1996, In : Biochimica et Biophysica Acta - Biomembranes. 1279, 2, p. 203-213 11 p.

Research output: Contribution to journalArticle

Calcium-Transporting ATPases
Sarcoplasmic Reticulum
Chemical activation
Calcium
Membranes
1997
24 Citations (Scopus)

Decreased conformational stability of the sarcoplasmic reticulum Ca- ATPase in aged skeletal muscle

Ferrington, D. A., Jones, T. E., Qin, Z., Miller-Schlyer, M., Squier, T. C. & Bigelow, D. J., Dec 4 1997, In : Biochimica et Biophysica Acta - Biomembranes. 1330, 2, p. 233-247 15 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Adenosine Triphosphatases
Muscle
Skeletal Muscle
Muscles
36 Citations (Scopus)

In vivo aging of rat skeletal muscle sarcoplasmic reticulum Ca-ATPase. Chemical analysis and quantitative simulation by exposure to low levels of peroxyl radicals

Viner, R. I., Ferrington, D. A., Aced, G. I., Miller-Schlyer, M., Bigelow, D. J. & Schöneich, C., Oct 23 1997, In : Biochimica et Biophysica Acta - Biomembranes. 1329, 2, p. 321-335 15 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Adenosine Triphosphatases
Muscle
Rats
Skeletal Muscle
19 Citations (Scopus)

Protein half-lives of calmodulin and the plasma membrane Ca-ATPase in rat brain

Ferrington, D. A., Chen, X., Krainev, A. G., Michaelis, E. K. & Bigelow, D. J., Aug 8 1997, In : Biochemical and Biophysical Research Communications. 237, 1, p. 163-165 3 p.

Research output: Contribution to journalArticle

Calmodulin
Cell membranes
Leucine
Adenosine Triphosphatases
Rats
5 Citations (Scopus)

Protein half-lives of two subunits of an NMDA receptor-like complex, the 71-kDa glutamate-binding and the 80-kDa CPP-binding protein

Chen, X., Ferrington, D. A., Bigelow, D. J. & Michaelis, E. K., Dec 8 1997, In : Biochemical and Biophysical Research Communications. 241, 1, p. 132-135 4 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Glutamic Acid
Carrier Proteins
Proteins
Radioactivity
1998
70 Citations (Scopus)

Altered turnover of calcium regulatory proteins of the sarcoplasmic reticulum in aged skeletal muscle

Ferrington, D. A., Krainev, A. G. & Bigelow, D. J., Mar 6 1998, In : Journal of Biological Chemistry. 273, 10, p. 5885-5891 7 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Muscle
Skeletal Muscle
Calcium
Leucine
1999
32 Citations (Scopus)

Age-related chemical modification of the skeletal muscle sarcoplasmic reticulum Ca-ATPase of the rat

Schöneich, C., Viner, R. I., Ferrington, D. A. & Bigelow, D. J., Mar 15 1999, In : Mechanisms of Ageing and Development. 107, 3, p. 221-231 11 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Adenosine Triphosphatases
Skeletal Muscle
Peroxynitrous Acid
Protein Isoforms
156 Citations (Scopus)

Diastereoselective reduction of protein-bound methionine sulfoxide by methionine sulfoxide reductase

Sharov, V. S., Ferrington, D. A., Squier, T. C. & Schöneich, C., Jul 23 1999, In : FEBS Letters. 455, 3, p. 247-250 4 p.

Research output: Contribution to journalArticle

Calmodulin
sulfoxide
Proteins
Oxidative stress
Liver
8 Citations (Scopus)

Effects of dietary protein on enzyme activity following exercise- induced muscle injury

Hayward, R., Ferrington, D. A., Kochanowski, L. A., Miller, L. M., Jaworsky, G. M. & Schneider, C. M., Jan 1 1999, In : Medicine and Science in Sports and Exercise. 31, 3, p. 414-420 7 p.

Research output: Contribution to journalArticle

Dietary Proteins
Muscles
Protein-Restricted Diet
Wounds and Injuries
Enzymes
243 Citations (Scopus)

Protein modification during biological aging: Selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle

Viner, R. I., Ferrington, D. A., Williams, T. D., Bigelow, D. J. & Schöneich, C., Jun 15 1999, In : Biochemical Journal. 340, 3, p. 657-669 13 p.

Research output: Contribution to journalArticle

Nitration
Calcium-Transporting ATPases
Sarcoplasmic Reticulum
Tyrosine
Muscle
137 Citations (Scopus)

Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase

Sun, H., Gao, J., Ferrington, D. A., Biesiada, H., Williams, T. D. & Squier, T. C., Jan 5 1999, In : Biochemistry. 38, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

Calmodulin
Cell membranes
Adenosine Triphosphatases
Repair
Cell Membrane
2000
16 Citations (Scopus)

Closer proximity between opposing domains of vertebrate calmodulin following deletion of Met145-Lys148

Yin, D., Sun, H., Ferrington, D. A. & Squier, T. C., Aug 22 2000, In : Biochemistry. 39, 33, p. 10255-10268 14 p.

Research output: Contribution to journalArticle

Calmodulin
Vertebrates
Cell membranes
Adenosine Triphosphatases
Cell Membrane
2001
17 Citations (Scopus)

Electron paramagnetic resonance: A high-resolution tool for muscle physiology

Thompson, L. V., Lowe, D. A., Ferrington, D. A. & Thomas, D. D., Jan 1 2001, In : Exercise and Sport Sciences Reviews. 29, 1, p. 3-6 4 p.

Research output: Contribution to journalArticle

Electron Spin Resonance Spectroscopy
Muscles
Muscle Relaxation
Myosins
Adenosine Triphosphatases
94 Citations (Scopus)

Selective degradation of oxidized calmodulin by the 20 S proteasome

Ferrington, D. A., Sun, H., Murray, K. K., Costa, J., Williams, T. D., Bigelow, D. J. & Squier, T. C., Jan 12 2001, In : Journal of Biological Chemistry. 276, 2, p. 937-943 7 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Calmodulin
Degradation
Hydrophobicity
Hydrophobic and Hydrophilic Interactions
2002
42 Citations (Scopus)

Comparable levels of Ca-ATPase inhibition by phospholamban in slow-twitch skeletal and cardiac sarcoplasmic reticulum

Ferrington, D. A., Yao, Q., Squier, T. C. & Bigelow, D. J., Nov 5 2002, In : Biochemistry. 41, 44, p. 13289-13296 8 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Adenosine Triphosphatases
Calcium
Phosphorylation
phospholamban
100 Citations (Scopus)
Fatty Acid-Binding Proteins
Antioxidants
Proteins
Lipids
Ionization
91 Citations (Scopus)

Proteasome function and protein oxidation in the aged retina

Louie, J. L., Kapphahn, B. & Ferrington, D. A., Jan 1 2002, In : Experimental Eye Research. 75, 3, p. 271-284 14 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Retina
Proteins
Chymotrypsin
Caseins
2003
53 Citations (Scopus)

Modified αA Crystallin in the Retina: Altered Expression and Truncation with Aging

Kapphahn, R. J., Ethen, C. M., Peters, E. A., Higgins, L. A. & Ferrington, D. A., Dec 30 2003, In : Biochemistry. 42, 51, p. 15310-15325 16 p.

Research output: Contribution to journalArticle

Crystallins
Retina
Aging of materials
Rats
Post Translational Protein Processing
2004
137 Citations (Scopus)

Altered proteasome function and subunit composition in aged muscle

Husom, A. D., Peters, E. A., Kolling, E. A., Fugere, N. A., Thompson, L. V. & Ferrington, D. A., Jan 1 2004, In : Archives of Biochemistry and Biophysics. 421, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Muscle
Muscles
Chemical analysis
Muscular Atrophy
93 Citations (Scopus)

Catalytic site-specific inhibition of the 20S proteasome by 4-hydroxynonenal

Ferrington, D. A. & Kapphahn, R. J., Dec 17 2004, In : FEBS Letters. 578, 3, p. 217-223 7 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Catalytic Domain
Chymotrypsin
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Electrophoresis, Gel, Two-Dimensional
28 Citations (Scopus)

Myofibrillar myosin ATPase activity in hindlimb muscles from young and aged rats

Lowe, D. A., Husom, A. D., Ferrington, D. A. & Thompson, L. V., Sep 1 2004, In : Mechanisms of Ageing and Development. 125, 9, p. 619-627 9 p.

Research output: Contribution to journalArticle

Myosins
Hindlimb
Muscle
Rats
Muscles
2005
15 Citations (Scopus)

Age-related differences in the adaptive potential of type I skeletal muscle fibers

Husom, A. D., Ferrington, D. A. & Thompson, L. V., Jan 1 2005, In : Experimental Gerontology. 40, 3, p. 227-235 9 p.

Research output: Contribution to journalArticle

Slow-Twitch Muscle Fibers
Skeletal Muscle Fibers
Muscle
Skeletal Muscle
Fibers
161 Citations (Scopus)

Altered proteasome structure, function, and oxidation in aged muscle

Ferrington, D. A., Husom, A. D. & Thompson, L. V., Apr 1 2005, In : FASEB Journal. 19, 6, p. 644-646 3 p.

Research output: Contribution to journalArticle

dithiothreitol
muscle protein
proteasome endopeptidase complex
calmodulin
skeletal muscle
20 Citations (Scopus)

Declines in arrestin and rhodopsin in the macula with progression of age-related macular degeneration

Ethen, C. M., Feng, X., Olsen, T. W. & Ferrington, D. A., Mar 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 3, p. 769-775 7 p.

Research output: Contribution to journalArticle

Arrestin
Rhodopsin
Macular Degeneration
Retinal Rod Photoreceptor Cells
Proteins
13 Citations (Scopus)

Identification of a novel phosphorylation site in ataxin-1

Vierra-Green, C. A., Orr, H. T., Zoghbi, H. Y. & Ferrington, D. A., May 15 2005, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1744, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Serine
Phosphorylation
Alanine
Transgenic Mice
2006
30 Citations (Scopus)

Different death stimuli evoke apoptosis via multiple pathways in retinal pigment epithelial cells

Ferrington, D. A., Tran, T. N., Lew, K. L., Van Remmen, H. & Gregerson, D. S., Sep 1 2006, In : Experimental Eye Research. 83, 3, p. 638-650 13 p.

Research output: Contribution to journalArticle

Retinal Pigments
Caspases
Epithelial Cells
Oxidants
Apoptosis
53 Citations (Scopus)

Myosin and actin expression and oxidation in aging muscle

Thompson, L. V., Durand, D., Fugere, N. A. & Ferrington, D. A., Dec 1 2006, In : Journal of Applied Physiology. 101, 6, p. 1581-1587 7 p.

Research output: Contribution to journalArticle

Myosins
Actins
Muscles
Skeletal Muscle
Proteins
44 Citations (Scopus)

Protein nitration with aging in the rat semimembranosus and soleus muscles

Fugere, N. A., Ferrington, D. A. & Thompson, L. D. V., Aug 2006, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 61, 8, p. 806-812 7 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Muscles
Proteins
Sarcoplasmic Reticulum Calcium-Transporting ATPases
Triose-Phosphate Isomerase
92 Citations (Scopus)

Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration

Nordgaard, C. L., Berg, K. M., Kapphahn, B., Reilly, C. S., Feng, X., Olsen, T. W. & Ferrington, D. A., Mar 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 3, p. 815-822 8 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Macular Degeneration
Proteomics
Proteins
Geographic Atrophy
65 Citations (Scopus)

Retinal proteins modified by 4-hydroxynonenal: Identification of molecular targets

Kapphahn, B., Giwa, B. M., Berg, K. M., Roehrich, H., Feng, X., Olsen, T. W. & Ferrington, D. A., Jul 1 2006, In : Experimental Eye Research. 83, 1, p. 165-175 11 p.

Research output: Contribution to journalArticle

Proteins
Triose-Phosphate Isomerase
Phosphopyruvate Hydratase
Electrophoresis, Gel, Two-Dimensional
Retina
12 Citations (Scopus)
Cytotoxic T-Lymphocytes
Epithelial Cells
Antigens
Antigen Presentation
Major Histocompatibility Complex
86 Citations (Scopus)

The proteome of central and peripheral retina with progression of age-related macular degeneration

Ethen, C. M., Reilly, C. S., Feng, X., Olsen, T. W. & Ferrington, D. A., Jun 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 6, p. 2280-2290 11 p.

Research output: Contribution to journalArticle

Macular Degeneration
Proteome
Retina
Proteins
Proteomics
2007
41 Citations (Scopus)

Age-dependent inhibition of proteasome chymotrypsin-like activity in the retina

Kapphahn, R. J., Bigelow, E. J. & Ferrington, D. A., Apr 1 2007, In : Experimental Eye Research. 84, 4, p. 646-654 9 p.

Research output: Contribution to journalArticle

Chymotrypsin
Proteasome Endopeptidase Complex
Retina
Cysteine
Caseins
63 Citations (Scopus)

Age-related macular degeneration and retinal protein modification by 4-hydroxy-2-nonenal

Ethen, C. M., Reilly, C., Feng, X., Olsen, T. W. & Ferrington, D. A., Aug 1 2007, In : Investigative Ophthalmology and Visual Science. 48, 8, p. 3469-3479 11 p.

Research output: Contribution to journalArticle

Macular Degeneration
Proteins
4-hydroxy-2-nonenal
Lipid Peroxidation
2-nonenal
106 Citations (Scopus)

Changes in Select Redox Proteins of the Retinal Pigment Epithelium in Age-related Macular Degeneration

Decanini, A., Nordgaard, C. L., Feng, X., Ferrington, D. A. & Olsen, T. W., Jan 1 2007, In : American journal of ophthalmology. 143, 4

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Macular Degeneration
Oxidation-Reduction
Proteins
Eye Diseases
25 Citations (Scopus)
Epithelial Cells
T-Lymphocytes
Major Histocompatibility Complex
Antigens
Coculture Techniques
59 Citations (Scopus)

Transformation of the proteasome with age-related macular degeneration

Ethen, C. M., Hussong, S. A., Reilly, C. S., Feng, X., Olsen, T. W. & Ferrington, D. A., Mar 6 2007, In : FEBS Letters. 581, 5, p. 885-890 6 p.

Research output: Contribution to journalArticle

Oxidative stress
Macular Degeneration
Proteasome Endopeptidase Complex
Retina
Chymotrypsin
2008
5 Citations (Scopus)

Age-dependent effects of treadmill exercise during a period of inactivity

Arora, P., Husom, A. D., Ferrington, D. A. & Thompson, L. V., Jul 1 2008, In : Experimental Gerontology. 43, 7, p. 668-673 6 p.

Research output: Contribution to journalArticle

Bearings (structural)
Exercise equipment
Exercise
Weight-Bearing
Rats
14 Citations (Scopus)

Carbonic anhydrase III and four-and-a-half LIM protein 1 are preferentially oxidized with muscle unloading

Chen, C. N., Ferrington, D. A. & Thompson, L. V., Nov 1 2008, In : Journal of applied physiology. 105, 5, p. 1554-1561 8 p.

Research output: Contribution to journalArticle

Carbonic Anhydrase III
Muscles
Proteins
Hindlimb Suspension
Muscle Proteins
67 Citations (Scopus)

Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers

Prochniewicz, E., Lowe, D. A., Spakowicz, D. J., Higgins, L., O'Conor, K., Thompson, L. V., Ferrington, D. A. & Thomas, D. D., Feb 1 2008, In : American Journal of Physiology - Cell Physiology. 294, 2

Research output: Contribution to journalArticle

Skeletal Muscle Fibers
Myosins
Hydrogen Peroxide
Peroxides
Myofibrils
54 Citations (Scopus)

Human retinal pigment epithelium proteome changes in early diabetes

Decanini, A., Karunadharma, P. R., Nordgaard, C. L., Feng, X., Olsen, T. W. & Ferrington, D. A., Jun 1 2008, In : Diabetologia. 51, 6, p. 1051-1061 11 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Proteome
Diabetic Retinopathy
Proteins
Mass Spectrometry
50 Citations (Scopus)

Immunoproteasome responds to injury in the retina and brain

Ferrington, D. A., Hussong, S. A., Roehrich, H., Kapphahn, B., Kavanaugh, S. M., Heuss, N. D. & Gregerson, D. S., Jul 1 2008, In : Journal of Neurochemistry. 106, 1, p. 158-169 12 p.

Research output: Contribution to journalArticle

Retina
Brain
T-cells
Cytotoxic T-Lymphocytes
Wounds and Injuries
100 Citations (Scopus)

Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration

Nordgaard, C. L., Karunadharma, P. P., Feng, X., Olsen, T. W. & Ferrington, D. A., Jul 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 7, p. 2848-2855 8 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Macular Degeneration
Proteomics
Mitochondrial Proteins
Mitochondria
2009
27 Citations (Scopus)

Site-specific methionine oxidation initiates calmodulin degradation by the 20S proteasome

Balog, E. M., Lockamy, E. L., Thomas, D. D. & Ferrington, D. A., Apr 7 2009, In : Biochemistry. 48, 13, p. 3005-3016 12 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Calmodulin
Methionine
Proteolysis
Degradation
2010
21 Citations (Scopus)

Aging impairs the expression of the catalytic subunit of glutamate cysteine ligase in soleus muscle under stress

Chen, C. N., Brown-Borg, H. M., Rakoczy, S. G., Ferrington, D. A. & Thompson, L. V., Apr 9 2010, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 65, 2, p. 129-137 9 p.

Research output: Contribution to journalArticle

Glutamate-Cysteine Ligase
Catalytic Domain
Skeletal Muscle
Extremities
Muscles
60 Citations (Scopus)

Immunoproteasome deficiency alters retinal proteasome's response to stress

Hussong, S. A., Kapphahn, B., Phillips, S. L., Maldonado, M. & Ferrington, D. A., Jun 1 2010, In : Journal of Neurochemistry. 113, 6, p. 1481-1490 10 p.

Research output: Contribution to journalArticle

Retinal Pigments
Proteasome Endopeptidase Complex
Retina
Oxidative stress
Up-Regulation
104 Citations (Scopus)

Mitochondrial DNA damage as a potential mechanism for Age-Related macular Degeneration

Karunadharma, P. P., Nordgaard, C. L., Olsen, T. W. & Ferrington, D. A., Nov 1 2010, In : Investigative Ophthalmology and Visual Science. 51, 11, p. 5470-5479 10 p.

Research output: Contribution to journalArticle

Macular Degeneration
Mitochondrial DNA
DNA Damage
Mitochondrial Genome
Retinal Pigment Epithelium