19942017

Research output per year

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Research Output

2017

Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks

Chaudhury, I. & Koepp, D. M., Mar 17 2017, In : Nucleic acids research. 45, 5, p. 2558-2570 13 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2016

Recovery from the DNA replication checkpoint

Chaudhury, I. & Koepp, D. M., Nov 2016, In : Genes. 7, 11, 94.

Research output: Contribution to journalReview article

6 Scopus citations
2015

Artificial targeting of misfolded cytosolic proteins to endoplasmic reticulum as a mechanism for clearance

Liu, F., Koepp, D. M. & Walters, K. J., Jul 14 2015, In : Scientific reports. 5, 12088.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Analyzing cell cycle-dependent degradation and ubiquitination in budding yeast

Kim, D. H. & Koepp, D., 2014, Cell Cycle Control: Mechanisms and Protocols. Humana Press Inc., p. 343-356 14 p. (Methods in Molecular Biology; vol. 1170).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Analyzing cell cycle-dependent degradation and ubiquitination in budding yeast

Kim, D. H. & Koepp, D. M., 2014, In : Methods in molecular biology (Clifton, N.J.). 1170, p. 343-356 14 p.

Research output: Contribution to journalArticle

Cell cycle regulation by protein degradation

Koepp, D. M., Jan 1 2014, Cell Cycle Control: Mechanisms and Protocols. Humana Press Inc., p. 61-73 13 p. (Methods in Molecular Biology; vol. 1170).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Cell cycle regulation by protein degradation

Koepp, D. M., 2014, Cell Cycle Control: Mechanisms and Protocols. Humana Press Inc., p. 61-73 13 p. (Methods in Molecular Biology; vol. 1170).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
2013

The saccharomyces cerevisiae F-Box Protein Dia2 is a mediator of S-Phase checkpoint recovery from DNA damage

Fong, C. M., Arumugam, A. & Koepp, D. M., Apr 24 2013, In : Genetics. 193, 2, p. 483-499 17 p.

Research output: Contribution to journalArticle

11 Scopus citations
2012

Hect E3 ubiquitin ligase Tom1 controls Dia2 degradation during the cell cycle

Kim, D. H. & Koepp, D. M., Nov 1 2012, In : Molecular biology of the cell. 23, 21, p. 4203-4211 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phase

Kim, D. H., Zhang, W. & Koepp, D. M., Dec 28 2012, In : Journal of Biological Chemistry. 287, 53, p. 44212-44220 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

The Stomatin-Like Protein SLP-1 and Cdk2 Interact with the F-Box Protein Fbw7-γ

Zhang, W., MacDonald, E. M. & Koepp, D. M., Oct 17 2012, In : PloS one. 7, 10, e47736.

Research output: Contribution to journalArticle

4 Scopus citations
2010

Activation of the S-phase checkpoint inhibits degradation of the F-box protein dia

Kile, A. C. & Koepp, D. M., Jan 1 2010, In : Molecular and cellular biology. 30, 1, p. 160-171 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

The replication stress response and the ubiquitin system: A new link in maintaining genomic integrity

Koepp, D. M., Mar 10 2010, In : Cell Division. 5, 8.

Research output: Contribution to journalComment/debate

4 Scopus citations

TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae

Tran, L. T., Wang'Ondu, R. W., Weng, J. B., Wanjiku, G. W., Fong, C. M., Kile, A. C., Koepp, D. & Hood-Degrenier, J. K., Dec 1 2010, In : Current Genetics. 56, 6, p. 479-493 15 p.

Research output: Contribution to journalArticle

2 Scopus citations
2008

The C. elegans L1CAM homologue LAD-2 functions as a coreceptor in MAB-20/Sema2-mediated axon guidance

Wang, X., Zhang, W., Cheever, T., Schwarz, V., Opperman, K., Hutter, H., Koepp, D. & Chen, L., Jan 14 2008, In : Journal of Cell Biology. 180, 1, p. 233-246 14 p.

Research output: Contribution to journalArticle

40 Scopus citations
2007

Ubiquitin Receptor Proteins hHR23a and hPLIC2 Interact

Kang, Y., Zhang, N., Koepp, D. M. & Walters, K. J., Jan 26 2007, In : Journal of Molecular Biology. 365, 4, p. 1093-1101 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Yra1 is required for S phase entry and affects Dia2 binding to replication origins

Swaminathan, S., Kile, A. C., MacDonald, E. M. & Koepp, D. M., Jul 1 2007, In : Molecular and cellular biology. 27, 13, p. 4674-4684 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2006

Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation

Liu, F., Zhang, N., Zhou, X., Hanna, P. E., Wagner, C. R., Koepp, D. M. & Walters, K. J., Aug 18 2006, In : Journal of Molecular Biology. 361, 3, p. 482-492 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Fbw7 isoform interaction contributes to cyclin E proteolysis

Zhang, W. & Koepp, D. M., Dec 1 2006, In : Molecular Cancer Research. 4, 12, p. 935-943 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

The F-box protein Dia2 regulates DNA replication

Koepp, D. M., Kile, A. C., Swaminathan, S. & Rodriguez-Rivera, V., Apr 1 2006, In : Molecular biology of the cell. 17, 4, p. 1540-1548 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2002

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

Zheng, N., Schulman, B. A., Song, L., Miller, J. J., Jeffrey, P. D., Wang, P., Chu, C., Koepp, D. M., Elledge, S. J., Pagano, M., Conaway, R. C., Conaway, J. W., Harper, J. W. & Pavletich, N. P., Apr 2002, In : Nature. 416, 6882, p. 703-709 7 p.

Research output: Contribution to journalArticle

1016 Scopus citations
2001

Phosphorylation-dependent ubiquitination of cyctin E by the SCFFbw7 ubiquitin ligase

Koepp, D. M., Schaefer, L. K., Ye, X., Keyomarsi, K., Chu, C., Harper, J. W. & Elledge, S. J., Oct 5 2001, In : Science. 294, 5540, p. 173-177 5 p.

Research output: Contribution to journalArticle

581 Scopus citations
1999

A family of mammalian F-box proteins

Winston, J. T., Koepp, D. M., Cihui, Z., Elledge, S. J. & Harper, J. W., Oct 21 1999, In : Current Biology. 9, 20, p. 1180-1182 3 p.

Research output: Contribution to journalArticle

292 Scopus citations

How the cyclin became a cyclin: Regulated proteolysis in the cell cycle

Koepp, D. M., Harper, J. W. & Elledge, S. J., May 14 1999, In : Cell. 97, 4, p. 431-434 4 p.

Research output: Contribution to journalReview article

379 Scopus citations

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

Kamura, T., Koepp, D. M., Conrad, M. N., Skowyra, D., Moreland, R. J., Iliopoulos, O., Lane, W. S., Kaelin, W. G., Elledge, S. J., Conaway, R. C., Harper, J. W. & Conaway, J. W., Apr 23 1999, In : Science. 284, 5414, p. 657-661 5 p.

Research output: Contribution to journalArticle

622 Scopus citations

Reconstitution of G1 cyclin ubiquitination with complexes containing SCF(Grr1) and Rbx1

Skowyra, D., Koepp, D. M., Kamura, T., Conrad, M. N., Conaway, R. C., Conaway, J. W., Elledge, S. J. & Harper, J. W., Apr 23 1999, In : Science. 284, 5414, p. 662-665 4 p.

Research output: Contribution to journalArticle

345 Scopus citations
1998

HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

Vodicka, M. A., Koepp, D. M., Silver, P. A. & Emerman, M., Jan 15 1998, In : Genes and Development. 12, 2, p. 175-185 11 p.

Research output: Contribution to journalArticle

277 Scopus citations

Nucleocytoplasmic transport and cell proliferation

Koepp, D. & Silver, P. A., Apr 17 1998, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1377, 2

Research output: Contribution to journalShort survey

11 Scopus citations

Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin β homologs NMD5 and XPO1

Ferrigno, P., Posas, F., Koepp, D., Saito, H. & Silver, P. A., Oct 1 1998, In : EMBO Journal. 17, 19, p. 5606-5614 9 p.

Research output: Contribution to journalArticle

327 Scopus citations
1996

A GTPase controlling nuclear trafficking: Running the right way or walking RANdomly?

Koepp, D. M. & Silver, P. A., Oct 1996, In : Cell. 87, 1, p. 1-4 4 p.

Research output: Contribution to journalReview article

140 Scopus citations

Dynamic localization of the nuclear import receptor and its interactions with transport factors

Koepp, D. M., Wong, D. H., Corbett, A. H. & Silver, P. A., Jul 5 1996, In : Journal of Cell Biology. 133, 6, p. 1163-1176 14 p.

Research output: Contribution to journalArticle

112 Scopus citations

Genetic analysis of macromolecular transport across the nuclear envelope

Corbett, A., Ferrigno, P., Henry, M., Kahana, J., Koepp, D., Lee, M., Nguyen, L., Schlenstedt, G., Seedorf, M., Shen, E., Taura, T., Wong, D. & Silver, P., Dec 15 1996, In : Experimental Cell Research. 229, 2, p. 212-216 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
1995

Mutants in a yeast Ran binding protein are defective in nuclear transport

Schlenstedt, G., Wong, D. H., Koepp, D. M. & Silver, P. A., Jan 1 1995, In : EMBO Journal. 14, 21, p. 5367-5378 12 p.

Research output: Contribution to journalArticle

135 Scopus citations

Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import

Corbett, A. H., Koepp, D. M., Schlenstedt, G., Lee, M. S., Hopper, A. K. & Silver, P. A., Sep 1 1995, In : Journal of Cell Biology. 130, 5, p. 1017-1026 10 p.

Research output: Contribution to journalArticle

148 Scopus citations
1994

Synergistic activation of transcription by bacteriophage λ cl protein and E. coli cAMP receptor protein

Joung, J. K., Koepp, D. M. & Hochschild, A., Jan 1 1994, In : Science. 265, 5180, p. 1863-1866 4 p.

Research output: Contribution to journalArticle

64 Scopus citations