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Research Output 1994 2017

2017
2 Citations (Scopus)

Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks

Chaudhury, I. & Koepp, D. M., Mar 17 2017, In : Nucleic acids research. 45, 5, p. 2558-2570 13 p.

Research output: Contribution to journalArticle

Open Access
S Phase Cell Cycle Checkpoints
Genetic Recombination
DNA Damage
DNA
Ligases
2016
5 Citations (Scopus)

Recovery from the DNA replication checkpoint

Chaudhury, I. & Koepp, D. M., Nov 2016, In : Genes. 7, 11, 94.

Research output: Contribution to journalReview article

S Phase Cell Cycle Checkpoints
DNA Replication
Cell Cycle
Genomic Instability
DNA
2015
2 Citations (Scopus)

Artificial targeting of misfolded cytosolic proteins to endoplasmic reticulum as a mechanism for clearance

Liu, F., Koepp, D. M. & Walters, K. J., Jul 14 2015, In : Scientific reports. 5, 12088.

Research output: Contribution to journalArticle

Endoplasmic Reticulum
Proteins
Proteasome Endopeptidase Complex
Mutation
Enzymes
2014
1 Citation (Scopus)

Analyzing cell cycle-dependent degradation and ubiquitination in budding yeast

Kim, D. H. & Koepp, D., 2014, Cell Cycle Control: Mechanisms and Protocols. Humana Press Inc., p. 343-356 14 p. (Methods in Molecular Biology; vol. 1170).

Research output: Chapter in Book/Report/Conference proceedingChapter

Saccharomycetales
Ubiquitination
Cell Cycle
Cell Cycle Proteins
Proteolysis

Analyzing cell cycle-dependent degradation and ubiquitination in budding yeast

Kim, D. H. & Koepp, D. M., 2014, In : Methods in molecular biology (Clifton, N.J.). 1170, p. 343-356 14 p.

Research output: Contribution to journalArticle

Saccharomycetales
Ubiquitination
Cell Cycle
Cell Cycle Proteins
Ubiquitin
4 Citations (Scopus)

Cell cycle regulation by protein degradation

Koepp, D. M., 2014, Cell Cycle Control: Mechanisms and Protocols. Humana Press Inc., p. 61-73 13 p. (Methods in Molecular Biology; vol. 1170).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Cycle Proteins
Proteolysis
Cell Cycle
Ubiquitin-Protein Ligases
Ubiquitin
1 Citation (Scopus)

Cell cycle regulation by protein degradation

Koepp, D. M., Jan 1 2014, Cell Cycle Control: Mechanisms and Protocols. Humana Press Inc., p. 61-73 13 p. (Methods in Molecular Biology; vol. 1170).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Cycle Proteins
Proteolysis
Cell Cycle
Ubiquitin-Protein Ligases
Cell Division
2013
11 Citations (Scopus)

The saccharomyces cerevisiae F-Box Protein Dia2 is a mediator of S-Phase checkpoint recovery from DNA damage

Fong, C. M., Arumugam, A. & Koepp, D. M., Apr 24 2013, In : Genetics. 193, 2, p. 483-499 17 p.

Research output: Contribution to journalArticle

S Phase Cell Cycle Checkpoints
F-Box Proteins
Saccharomyces cerevisiae Proteins
DNA Damage
Methyl Methanesulfonate
2012
9 Citations (Scopus)

Hect E3 ubiquitin ligase Tom1 controls Dia2 degradation during the cell cycle

Kim, D. H. & Koepp, D. M., Nov 1 2012, In : Molecular biology of the cell. 23, 21, p. 4203-4211 9 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
S Phase
Cell Cycle
Ubiquitination
Ubiquitin
12 Citations (Scopus)

The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phase

Kim, D. H., Zhang, W. & Koepp, D. M., Dec 28 2012, In : Journal of Biological Chemistry. 287, 53, p. 44212-44220 9 p.

Research output: Contribution to journalArticle

F-Box Proteins
Ubiquitin-Protein Ligases
Ubiquitination
G1 Phase
Cell Cycle
4 Citations (Scopus)

The Stomatin-Like Protein SLP-1 and Cdk2 Interact with the F-Box Protein Fbw7-γ

Zhang, W., MacDonald, E. M. & Koepp, D. M., Oct 17 2012, In : PloS one. 7, 10, e47736.

Research output: Contribution to journalArticle

F-Box Proteins
F-box proteins
cyclin-dependent kinase
Ubiquitin
Cell Proliferation
2010
11 Citations (Scopus)

Activation of the S-phase checkpoint inhibits degradation of the F-box protein dia

Kile, A. C. & Koepp, D. M., Jan 1 2010, In : Molecular and cellular biology. 30, 1, p. 160-171 12 p.

Research output: Contribution to journalArticle

S Phase Cell Cycle Checkpoints
F-Box Proteins
Proteolysis
Ubiquitin
Nuclear Localization Signals
4 Citations (Scopus)

The replication stress response and the ubiquitin system: A new link in maintaining genomic integrity

Koepp, D. M., Mar 10 2010, In : Cell Division. 5, 8.

Research output: Contribution to journalComment/debate

S Phase Cell Cycle Checkpoints
Proteolysis
Ubiquitin
Cells
Cell Cycle
2 Citations (Scopus)

TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae

Tran, L. T., Wang'Ondu, R. W., Weng, J. B., Wanjiku, G. W., Fong, C. M., Kile, A. C., Koepp, D. & Hood-Degrenier, J. K., Dec 1 2010, In : Current Genetics. 56, 6, p. 479-493 15 p.

Research output: Contribution to journalArticle

Spindle Apparatus
Cyclins
Sirolimus
DNA Replication
S Phase
2008
40 Citations (Scopus)

The C. elegans L1CAM homologue LAD-2 functions as a coreceptor in MAB-20/Sema2-mediated axon guidance

Wang, X., Zhang, W., Cheever, T., Schwarz, V., Opperman, K., Hutter, H., Koepp, D. & Chen, L., Jan 14 2008, In : Journal of Cell Biology. 180, 1, p. 233-246 14 p.

Research output: Contribution to journalArticle

Neural Cell Adhesion Molecule L1
Neuropilins
Genes
Semaphorin-3A
Semaphorins
2007
23 Citations (Scopus)

Ubiquitin Receptor Proteins hHR23a and hPLIC2 Interact

Kang, Y., Zhang, N., Koepp, D. M. & Walters, K. J., Jan 26 2007, In : Journal of Molecular Biology. 365, 4, p. 1093-1101 9 p.

Research output: Contribution to journalArticle

Ubiquitin
Proteins
Proteasome Endopeptidase Complex
Proteolysis
Magnetic Resonance Spectroscopy
16 Citations (Scopus)

Yra1 is required for S phase entry and affects Dia2 binding to replication origins

Swaminathan, S., Kile, A. C., MacDonald, E. M. & Koepp, D. M., Jul 1 2007, In : Molecular and cellular biology. 27, 13, p. 4674-4684 11 p.

Research output: Contribution to journalArticle

Replication Origin
DNA Replication
S Phase
Chromatin
F-Box Proteins
2006
32 Citations (Scopus)

Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation

Liu, F., Zhang, N., Zhou, X., Hanna, P. E., Wagner, C. R., Koepp, D. M. & Walters, K. J., Aug 18 2006, In : Journal of Molecular Biology. 361, 3, p. 482-492 11 p.

Research output: Contribution to journalArticle

Arylamine N-Acetyltransferase
Ubiquitination
Cricetinae
Mutation
Tryptophan
50 Citations (Scopus)

Fbw7 isoform interaction contributes to cyclin E proteolysis

Zhang, W. & Koepp, D. M., Dec 1 2006, In : Molecular Cancer Research. 4, 12, p. 935-943 9 p.

Research output: Contribution to journalArticle

Cyclin E
F-Box Proteins
Ubiquitin
Proteolysis
Protein Isoforms
35 Citations (Scopus)

The F-box protein Dia2 regulates DNA replication

Koepp, D. M., Kile, A. C., Swaminathan, S. & Rodriguez-Rivera, V., Apr 1 2006, In : Molecular biology of the cell. 17, 4, p. 1540-1548 9 p.

Research output: Contribution to journalArticle

F-Box Proteins
DNA Replication
Cell Cycle
Ubiquitin
S Phase
2002
1014 Citations (Scopus)

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

Zheng, N., Schulman, B. A., Song, L., Miller, J. J., Jeffrey, P. D., Wang, P., Chu, C., Koepp, D. M., Elledge, S. J., Pagano, M., Conaway, R. C., Conaway, J. W., Harper, J. W. & Pavletich, N. P., Apr 2002, In : Nature. 416, 6882, p. 703-709 7 p.

Research output: Contribution to journalArticle

SKP Cullin F-Box Protein Ligases
Ubiquitin-Conjugating Enzymes
Proteins
RING Finger Domains
Ubiquitin-Protein Ligases
2001
579 Citations (Scopus)

Phosphorylation-dependent ubiquitination of cyctin E by the SCFFbw7 ubiquitin ligase

Koepp, D. M., Schaefer, L. K., Ye, X., Keyomarsi, K., Chu, C., Harper, J. W. & Elledge, S. J., Oct 5 2001, In : Science. 294, 5540, p. 173-177 5 p.

Research output: Contribution to journalArticle

Cyclin E
Ubiquitination
Ligases
Ubiquitin
Phosphorylation
1999
290 Citations (Scopus)

A family of mammalian F-box proteins

Winston, J. T., Koepp, D. M., Cihui, Z., Elledge, S. J. & Harper, J. W., Oct 21 1999, In : Current Biology. 9, 20, p. 1180-1182 3 p.

Research output: Contribution to journalArticle

F-Box Proteins
F-box proteins
F-Box Motifs
ubiquitin-protein ligase
Yeast
379 Citations (Scopus)

How the cyclin became a cyclin: Regulated proteolysis in the cell cycle

Koepp, D. M., Harper, J. W. & Elledge, S. J., May 14 1999, In : Cell. 97, 4, p. 431-434 4 p.

Research output: Contribution to journalReview article

Proteolysis
Cyclins
Cells
622 Citations (Scopus)

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

Kamura, T., Koepp, D. M., Conrad, M. N., Skowyra, D., Moreland, R. J., Iliopoulos, O., Lane, W. S., Kaelin, W. G., Elledge, S. J., Conaway, R. C., Harper, J. W. & Conaway, J. W., Apr 23 1999, In : Science. 284, 5414, p. 657-661 5 p.

Research output: Contribution to journalArticle

SKP Cullin F-Box Protein Ligases
Ubiquitination
Cullin Proteins
Neoplasms
Cyclin-Dependent Kinases
344 Citations (Scopus)

Reconstitution of G1 cyclin ubiquitination with complexes containing SCF(Grr1) and Rbx1

Skowyra, D., Koepp, D. M., Kamura, T., Conrad, M. N., Conaway, R. C., Conaway, J. W., Elledge, S. J. & Harper, J. W., Apr 23 1999, In : Science. 284, 5414, p. 662-665 4 p.

Research output: Contribution to journalArticle

Cyclin G1
F-Box Proteins
Ubiquitination
Cyclins
Ubiquitin-Protein Ligases
1998
277 Citations (Scopus)

HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

Vodicka, M. A., Koepp, D. M., Silver, P. A. & Emerman, M., Jan 15 1998, In : Genes and Development. 12, 2, p. 175-185 11 p.

Research output: Contribution to journalArticle

Karyopherins
Cell Nucleus Active Transport
HIV-1
Macrophages
Nuclear Pore Complex Proteins
11 Citations (Scopus)

Nucleocytoplasmic transport and cell proliferation

Koepp, D. & Silver, P. A., Apr 17 1998, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1377, 2

Research output: Contribution to journalShort survey

Biological Transport
Karyopherins
Cell Nucleus Active Transport
Nuclear Envelope
Nuclear Proteins
327 Citations (Scopus)

Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin β homologs NMD5 and XPO1

Ferrigno, P., Posas, F., Koepp, D., Saito, H. & Silver, P. A., Oct 1 1998, In : EMBO Journal. 17, 19, p. 5606-5614 9 p.

Research output: Contribution to journalArticle

Karyopherins
Phosphotransferases
Cell Nucleus Active Transport
MAP Kinase Signaling System
Mitogen-Activated Protein Kinase Kinases
1996
140 Citations (Scopus)

A GTPase controlling nuclear trafficking: Running the right way or walking RANdomly?

Koepp, D. M. & Silver, P. A., Oct 1996, In : Cell. 87, 1, p. 1-4 4 p.

Research output: Contribution to journalReview article

GTP Phosphohydrolases
113 Citations (Scopus)

Dynamic localization of the nuclear import receptor and its interactions with transport factors

Koepp, D. M., Wong, D. H., Corbett, A. H. & Silver, P. A., Jul 5 1996, In : Journal of Cell Biology. 133, 6, p. 1163-1176 14 p.

Research output: Contribution to journalArticle

Karyopherins
Cell Nucleus Active Transport
Cytoplasmic and Nuclear Receptors
Nuclear Localization Signals
Guanosine Triphosphate
6 Citations (Scopus)

Genetic analysis of macromolecular transport across the nuclear envelope

Corbett, A., Ferrigno, P., Henry, M., Kahana, J., Koepp, D., Lee, M., Nguyen, L., Schlenstedt, G., Seedorf, M., Shen, E., Taura, T., Wong, D. & Silver, P., Dec 15 1996, In : Experimental Cell Research. 229, 2, p. 212-216 5 p.

Research output: Contribution to journalArticle

Nuclear Pore Complex Proteins
Nuclear Pore
Saccharomycetales
Cell Nucleus Active Transport
Nuclear Envelope
1995
135 Citations (Scopus)

Mutants in a yeast Ran binding protein are defective in nuclear transport

Schlenstedt, G., Wong, D. H., Koepp, D. M. & Silver, P. A., Jan 1 1995, In : EMBO Journal. 14, 21, p. 5367-5378 12 p.

Research output: Contribution to journalArticle

ran GTP-Binding Protein
Fungal Proteins
Cell Nucleus Active Transport
Yeast
Carrier Proteins
148 Citations (Scopus)

Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import

Corbett, A. H., Koepp, D. M., Schlenstedt, G., Lee, M. S., Hopper, A. K. & Silver, P. A., Sep 1 1995, In : Journal of Cell Biology. 130, 5, p. 1017-1026 10 p.

Research output: Contribution to journalArticle

ran GTP-Binding Protein
GTPase-Activating Proteins
Cell Nucleus Active Transport
Cytosol
Proteins
1994
64 Citations (Scopus)

Synergistic activation of transcription by bacteriophage λ cl protein and E. coli cAMP receptor protein

Joung, J. K., Koepp, D. M. & Hochschild, A., Jan 1 1994, In : Science. 265, 5180, p. 1863-1866 4 p.

Research output: Contribution to journalArticle

Bacteriophages
Transcriptional Activation
DNA-Directed RNA Polymerases
Cyclic AMP Receptor Protein
Proteins