20062021

Research output per year

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Research Output

A double blinded, placebo-controlled pilot study to examine reduction of CD34+/CD117+/CD133+ lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma

Modiano, J., Ito, D., Childress, M., Mason, N., Winter, A., O'Brien, T., Henson, M., Borgatti, A., Lewellen, M., Krick, E., Stewart, J., Lahrman, S., Rajwa, B., Scott, M. C., Seelig, D., Koopmeiners, J. & Ruetz, S., Jan 1 2017, In : F1000Research. 4, 42.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A double blinded, placebo-controlled pilot study to examine reduction of CD34+ /CD117+ /CD133+ lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma

Ito, D., Childress, M., Mason, N., Winter, A., O'Brien, T., Henson, M., Borgatti, A., Lewellen, M., Krick, E., Stewart, J., Lahrman, S., Rajwa, B., Scott, M. C., Seelig, D., Koopmeiners, J., Ruetz, S. & Modiano, J., Jan 1 2017, In : F1000Research. 4, 42.

Research output: Contribution to journalArticle

2 Scopus citations

Aerosol and nasal transmission of chronic wasting disease in cervidized mice

Denkers, N. D., Seelig, D. M., Telling, G. C. & Hoover, E. A., Jun 1 2010, In : Journal of General Virology. 91, 6, p. 1651-1658 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Aerosol transmission of chronic wasting disease in white-tailed deer

Denkers, N. D., Hayes-Klug, J., Anderson, K. R., Seelig, D. M., Haley, N. J., Dahmes, S. J., Osborn, D. A., Miller, K. V., Warren, R. J., Mathiason, C. K. & Hoover, E. A., Feb 1 2013, In : Journal of virology. 87, 3, p. 1890-1892 3 p.

Research output: Contribution to journalArticle

45 Scopus citations

All lesions great and small, part 1: Diagnostic cytology in veterinary medicine

Sharkey, L. C., Seelig, D. & Overmann, J., Jun 2014, In : Diagnostic Cytopathology. 42, 6, p. 535-543 9 p.

Research output: Contribution to journalReview article

4 Scopus citations

All lesions great and small, part 2. Diagnostic cytology in veterinary medicine

Sharkey, L. C., Seelig, D. & Overmann, J. A., Jun 2014, In : Diagnostic Cytopathology. 42, 6, p. 544-552 9 p.

Research output: Contribution to journalReview article

1 Scopus citations

Alteration of the chronic wasting disease species barrier by in vitro prion amplification

Kurt, T. D., Seelig, D. M., Schneider, J. R., Johnson, C. J., Telling, G. C., Heisey, D. M. & Hoover, E. A., Sep 1 2011, In : Journal of virology. 85, 17, p. 8528-8537 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Anticancer effects of resveratrol in canine hemangiosarcoma cell lines

Carlson, A., Alderete, K. S., Grant, M. K. O., Seelig, D. M., Sharkey, L. C. & Zordoky, B. N. M., Jun 2018, In : Veterinary and Comparative Oncology. 16, 2, p. 253-261 9 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Assessment of eosinophils in gastrointestinal inflammatory disease of dogs

Bastan, I., Rendahl, A. K., Seelig, D., Day, M. J., Hall, E. J., Rao, S. P., Washabau, R. J. & Sriramarao, P., Nov 1 2018, In : Journal of veterinary internal medicine. 32, 6, p. 1911-1917 7 p.

Research output: Contribution to journalArticle

Open Access

Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose

Laudenbach, M., Baruffaldi, F., Robinson, C., Carter, P., Seelig, D., Baehr, C. & Pravetoni, M., Dec 1 2018, In : Scientific reports. 8, 1, 5508.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Calibrated bioresorbable microspheres as an embolic agent: An experimental study in a rabbit renal model

Weng, L., Seelig, D., Rostamzadeh, P. & Golzarian, J., Dec 2015, In : Journal of Vascular and Interventional Radiology. 26, 12, p. 1887-1894.e1

Research output: Contribution to journalArticle

12 Scopus citations

Canine t-zone lymphoma: Unique immunophenotypic features, outcome, and population characteristics

Seelig, D. M., Avery, P., Webb, T., Yoshimoto, J., Bromberek, J., Ehrhart, E. J. & Avery, A. C., Jan 1 2014, In : Journal of veterinary internal medicine. 28, 3, p. 878-886 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Central nervous system injury - A newly observed bystander effect of radiation

Feiock, C., Yagi, M., Maidman, A., Rendahl, A., Hui, S. & Seelig, D., Sep 2016, In : PloS one. 11, 9, e0163233.

Research output: Contribution to journalArticle

5 Scopus citations

Chronic wasting disease prion trafficking via the autonomic nervous system

Seelig, D. M., Mason, G. L., Telling, G. C. & Hoover, E. A., Sep 1 2011, In : American Journal of Pathology. 179, 3, p. 1319-1328 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Clinical challenge

Linden, M. A., Williams, S. A., Forster, C., Croonquist, P., Braido, J., Danneman, S., Beckel, M., Callahan, M. & Seelig, D., Sep 1 2016, In : Journal of Zoo and Wildlife Medicine. 47, 3, p. 948-951 4 p.

Research output: Contribution to journalArticle

Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies

Seelig, D. M., Ito, D., Forster, C. L., Yoon, U. A., Breen, M., Burns, L. J., Bachanova, V., Lindblad-Toh, K., O’Brien, T. D., Schmechel, S. C., Rizzardi, A. E., Modiano, J. F. & Linden, M. A., Jul 3 2017, In : Leukemia and Lymphoma. 58, 7, p. 1702-1710 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay

Haley, N. J., Seelig, D. M., Zabel, M. D., Telling, G. C. & Hoover, E. A., Mar 18 2009, In : PloS one. 4, 3, e4848.

Research output: Contribution to journalArticle

151 Scopus citations

Diagnostic utility of renal fine-needle aspirate cytology and ultrasound in the cat

McAloney, C. A., Sharkey, L. C., Feeney, D. A. & Seelig, D. M., Jun 1 2018, In : Journal of Feline Medicine and Surgery. 20, 6, p. 544-553 10 p.

Research output: Contribution to journalArticle

Early assessment of dosimetric and biological differences of total marrow irradiation versus total body irradiation in rodents

Hui, S., Takahashi, Y., Holtan, S. G., Azimi, R., Seelig, D., Yagi, M., Ingvalson, J., Alaei, P., Sharkey, L., Kodal, B., Peterson, N., Meyer, C., Godin, L., Ehrhardt, M., Storme, G., Zhou, D. & Panoskaltsis-Mortari, A., Sep 2017, In : Radiotherapy and Oncology. 124, 3, p. 468-474 7 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Establishment of a Patient-Derived Xenograft of Canine Enteropathy-Associated T-Cell Lymphoma, Large Cell Type

Im, K. S., Kim, J. H., Graef, A. J., Cornax, I., Seelig, D. M., O'Sullivan, M. G., Kovi, R. C. & Modiano, J. F., Jan 1 2017, In : Journal of Comparative Pathology. 156, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Evaluation of the diagnostic utility of cytologic examination of renal fine-needle aspirates from dogs and the use of ultrasonographic features to inform cytologic diagnosis

McAloney, C. A., Sharkey, L. C., Feeney, D. A., Seelig, D. M., Avery, A. C. & Jessen, C. R., May 15 2018, In : Journal of the American Veterinary Medical Association. 252, 10, p. 1247-1256 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Flow cytometric characterization and clinical outcome of CD4+ T-cell lymphoma in dogs: 67 cases

Avery, P. R., Burton, J., Bromberek, J. L., Seelig, D. M., Elmslie, R., Correa, S., Ehrhart, E. J., Morley, P. S. & Avery, A. C., Jan 1 2014, In : Journal of veterinary internal medicine. 28, 2, p. 538-546 9 p.

Research output: Contribution to journalArticle

29 Scopus citations
Open Access
13 Scopus citations

Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease

Michel, B., Ferguson, A., Johnson, T., Bender, H., Meyerett-Reid, C., Pulford, B., Von Teichman, A., Seelig, D., Weis, J. H., Telling, G. C., Aguzzi, A. & Zabel, M. D., Nov 1 2012, In : Journal of Immunology. 189, 9, p. 4520-4527 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Goitrous hypothyroidism associated with treatment with trimethoprim- sulfamethoxazole in a young dog

Seelig, D. M., Whittemore, J. C., Lappin, M. R., Myers, A. M. & Avery, P. R., Apr 15 2008, In : Journal of the American Veterinary Medical Association. 232, 8, p. 1181-1185 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Indolent T-cell-rich small B-cell hepatic lymphoma in a Golden Retriever

Rout, E. D., Hughes, K. L., Boostrom, B. O., Seelig, D. M., Avery, A. C. & Avery, P. R., Aug 2018, In : Clinical Case Reports. 6, 8, p. 1436-1444 9 p.

Research output: Contribution to journalArticle

Open Access

Infectious prions in the saliva and blood of deer with chronic wasting disease

Mathiason, C. K., Powers, J. G., Dahmes, S. J., Osborn, D. A., Miller, K. V., Warren, R. J., Mason, G. L., Hays, S. A., Hayes-Klug, J., Seelig, D. M., Wild, M. A., Wolfe, L. L., Spraker, T. R., Miller, M. W., Sigurdson, C. J., Telling, G. C. & Hoover, E. A., Oct 6 2006, In : Science. 314, 5796, p. 133-136 4 p.

Research output: Contribution to journalArticle

328 Scopus citations

Lesion Profiling and Subcellular Prion Localization of Cervid Chronic Wasting Disease in Domestic Cats

Seelig, D. M., Nalls, A. V., Flasik, M., Frank, V., Eaton, S., Mathiason, C. K. & Hoover, E. A., Jan 29 2015, In : Veterinary pathology. 52, 1, p. 107-119 13 p.

Research output: Contribution to journalArticle

5 Scopus citations
2 Scopus citations

Monoclonal gammopathy without hyperglobulinemia in 2 dogs with IgA secretory neoplasms

Seelig, D. M., Perry, J. A., Avery, A. C. & Avery, P. R., Dec 1 2010, In : Veterinary Clinical Pathology. 39, 4, p. 447-453 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Monoclonal immunoglobulin protein production in two dogs with secretory B-cell lymphoma with Mott cell differentiation

Seelig, D. M., Perry, J. A., Zaks, K., Avery, A. C. & Avery, P. R., Dec 1 2011, In : Journal of the American Veterinary Medical Association. 239, 11, p. 1477-1482 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Mother to Offspring Transmission of Chronic Wasting Disease in Reeves' Muntjac Deer

Nalls, A. V., McNulty, E., Powers, J., Seelig, D. M., Hoover, C., Haley, N. J., Hayes-Klug, J., Anderson, K., Stewart, P., Goldmann, W., Hoover, E. A. & Mathiason, C. K., Aug 14 2013, In : PloS one. 8, 8, e71844.

Research output: Contribution to journalArticle

40 Scopus citations

Pathogenesis of chronic wasting disease in cervidized transgenic mice

Seelig, D. M., Mason, G. L., Telling, G. C. & Hoover, E. A., Jun 2010, In : American Journal of Pathology. 176, 6, p. 2785-2797 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pathology in practice

Benson, C. J., Stiller, A. T., Corbin, E. E. & Seelig, D. M., Jan 1 2015, In : Journal of the American Veterinary Medical Association. 246, 9, p. 973-975 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Potential approaches for heterologous prion protein treatment of prion diseases

Seelig, D. M., Goodman, P. A. & Skinner, P. J., Jan 2 2016, In : Prion. 10, 1, p. 18-24 7 p.

Research output: Contribution to journalComment/debate

5 Scopus citations

Prion-seeding activity in cerebrospinal fluid of deer with chronic wasting disease

Haley, N. J., Van De Motter, A., Carver, S., Henderson, D., Davenport, K., Seelig, D. M., Mathiason, C. & Hoover, E., Nov 25 2013, In : PloS one. 8, 11, e81488.

Research output: Contribution to journalArticle

28 Scopus citations

Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells

Nelson, C. E., Mills, L. J., McCurtain, J. L., Thompson, E. A., Seelig, D. M., Bhela, S., Quarnstrom, C. F., Fife, B. T. & Vezys, V., Feb 12 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 7, p. 2640-2645 6 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens

Nelson, C. E., Thompson, E. A., Quarnstrom, C. F., Fraser, K. A., Seelig, D. M., Bhela, S., Burbach, B. J., Masopust, D. & Vezys, V., Sep 17 2019, In : Cell reports. 28, 12, p. 3092-3104.e5

Research output: Contribution to journalArticle

Open Access
Open Access
5 Scopus citations

Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice

Grant, M. K. O., Seelig, D. M., Sharkey, L. C., Choi, W. S. V., Abdelgawad, I. Y. & Zordoky, B. N., Feb 2019, In : PloS one. 14, 2, e0212486.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Susceptibility of domestic cats to chronic wasting disease

Mathiason, C. K., Nalls, A. V., Seelig, D. M., Kraft, S. L., Carnes, K., Anderson, K. R., Hayes-Klug, J. & Hoovera, E. A., Feb 1 2013, In : Journal of virology. 87, 4, p. 1947-1956 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
7 Scopus citations

The comparative diagnostic features of canine and human lymphoma

Seelig, D. M., Avery, A. C., Ehrhart, E. J. & Linden, M. A., Jun 1 2016, In : Veterinary Sciences. 3, 2, 11.

Research output: Contribution to journalReview article

22 Scopus citations

The use, publication and future directions of immunocytochemistry in veterinary medicine: a consensus of the Oncology-Pathology Working Group

Priest, H. L., Hume, K. R., Killick, D., Kozicki, A., Rizzo, V. L., Seelig, D., Snyder, L. A., Springer, N. L., Wright, Z. M. & Robat, C., Sep 2017, In : Veterinary and Comparative Oncology. 15, 3, p. 868-880 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

The utility of diagnostic tests for immune-mediated hemolytic anemia

Members of the Veterinary and Comparative Clinical Immunology Society Diagnostic Task Force, Oct 1 2019, In : Veterinary Clinical Pathology. 48, S1, p. 7-16 10 p.

Research output: Contribution to journalReview article

1 Scopus citations

Transmission of chronic wasting disease identifies a prion strain causing cachexia and heart infection in hamsters

Bessen, R. A., Robinson, C. J., Seelig, D. M., Watschke, C. P., Lowe, D., Shearin, H., Martinka, S. & Babcock, A. M., Dec 14 2011, In : PloS one. 6, 12, e28026.

Research output: Contribution to journalArticle

13 Scopus citations

Treatment of prion disease with heterologous prion proteins

Skinner, P. J., Kim, H. O., Bryant, D., Kinzel, N. J., Reilly, C., Priola, S. A., Ward, A. E., Goodman, P. A., Olson, K. & Seelig, D. M., Jul 2 2015, In : PloS one. 10, 7, e0131993.

Research output: Contribution to journalArticle

7 Scopus citations

WE‐E‐108‐08: Dosimetric and Biological Benchmarking of a Murine Total Marrow Irradiation Platform

Azimi, R., Alaei, P., Takahashi, Y., Spezi, E., Yagi, M., Arentsen, L., Sharkey, L., Seelig, D., Schappa, J. & Hui, S., Jun 2013, In : Medical Physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

What is your diagnosis? Pancytopenia in a dog

Williams, M. J., Gardiner, D., Seelig, D. & Olver, C. S., Dec 1 2008, In : Veterinary Clinical Pathology. 37, 4, p. 429-433 5 p.

Research output: Contribution to journalArticle

1 Scopus citations