1992 …2022
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Research Output 1992 2019

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12 Citations (Scopus)

A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement

Macchi, Z., Wang, Y., Moore, D., Katz, J., Saperstein, D., Walk, D., Simpson, E., Genge, A., Bertorini, T., Fernandes, J. A., Swenson, A., Elman, L., Dimachkie, M., Herbelin, L., Miller, J., Lu, J., Wilkins, H., Swerdlow, R. H., Statland, J. & Barohn, R., Aug 27 2015, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 16, 5-6, p. 345-352 8 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Biomarkers
Placebos
Monoamine Oxidase Inhibitors
Mitochondrial Membrane Potential
15 Citations (Scopus)

Amyotrophic lateral sclerosis: An emerging era of collaboratie gene discovery

Gwinn, K., Corriveau, R. A., Mitsumoto, H., Bednarz, K., Brown, R. H., Cudkowicz, M., Gordon, P. H., Hardy, J., Kasarskis, E. J., Kaufmann, P., Miller, R., Sorenson, E., Tandan, R., Traynor, B. J., Nash, J., Sherman, A., Mailman, M. D., Ostell, J., Bruijn, L., Cwik, V. & 30 others, Rich, S. S., Singleton, A., Refolo, L., Andrews, J., Zhang, R., Conwit, R., Keller, M. A., Lomen-Hoerth, C., Simmons, Z., Newman, D. S., Barohn, R. J., Crum, B., Stevens, J. C., Simpson, E. P., Boylan, K. B., McCluskey, L., Bedlack, R. S., Bosch, E. P., Barkhaus, P. E., Dibernardo, A., Caress, J. B., Lacomis, D., Pestronk, A., Shefner, J. M., Maragakis, N. J., Heitzman, D., Goslin, K. L., Jackson, C. E., Glass, J. D. & Mozaffar, T., Dec 5 2007, In : PloS one. 2, 12, e1254.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Genetic Association Studies
Genes
Motor Neuron Disease
motor neurons
13 Citations (Scopus)

Aplastic anemia associated with ticlopidine

Shapiro, C. M. & Walk, D., Jan 1 1996, In : Neurology. 47, 1, 1 p.

Research output: Contribution to journalArticle

Ticlopidine
Aplastic Anemia
116 Citations (Scopus)

A Randomized, Controlled, Open-Label Study of the Long-Term Effects of NGX-4010, a High-Concentration Capsaicin Patch, on Epidermal Nerve Fiber Density and Sensory Function in Healthy Volunteers

Kennedy, W. R., Vanhove, G. F., Lu, S. P., Tobias, J., Bley, K. R., Walk, D., Wendelschafer-Crabb, G., Simone, D. A. & Selim, M. M., Jun 1 2010, In : Journal of Pain. 11, 6, p. 579-587 9 p.

Research output: Contribution to journalArticle

Capsaicin
Nerve Fibers
Healthy Volunteers
Touch
Pain
177 Citations (Scopus)

Characteristics of motor unit discharge in subjects with hemiparesis

Gemperline, J. J., Allen, S., Walk, D. & Rymer, W. Z., Jan 1 1995, In : Muscle & Nerve. 18, 10, p. 1101-1114 14 p.

Research output: Contribution to journalArticle

Paresis
Muscles
Motor Neurons
Torque
Muscle Contraction
48 Citations (Scopus)
Nerve Fibers
Routine Diagnostic Tests
Foot
Small Fiber Neuropathy
Biopsy
39 Citations (Scopus)

Cooperative international neuromuscular research group duchenne natural history study demonstrates insufficient diagnosis and treatment of cardiomyopathy in duchenne muscular dystrophy

Spurney, C., Shimizu, R., Morgenroth, L. P., Kolski, H., Gordish-Dressman, H., Clemens, P. R., Cregan, M., Goude, E., Glick, M., Johnson, L., Han, J., Joyce, N., Kilmer, D., Nicorici, A., Chidambaranathan, C., Kumar, S., Eliasoph, L., Hosaki, E., Gonzales, A., Harris, V. & 83 others, Chiu, A., Thannhauser, J., Walker, L., Wright, C., Yousefi, M., Alhander, A. C., Wahlgren, L., Ekstrom, A. B., Kroksmark, A. K., Sterky, U., Birkmeier, M., Duong, T., Kaminski, S., Carroll, K., DeValle, K., Kennedy, R., Kornberg, A., Rodriguez, V., Villano, D., Leve, A. B., Wisband, E., Yaffe, D., Andreone, L., Corderi, J., Mesa, L., Levi, L., Coleman-Wood, K., Hoffman, A., Korn-Petersen, W., Kuntz, N., Selcen, D., Abdel-Hamid, H., Bise, C., Craig, A., Nguyen, C., Weimer, J., Al-Lozi, M., Florence, J., Golumbak, P., Lopate, G., Malane, J., Malkus, B., Renna, R., Schierbacker, J., Seiner, C., Wulf, C., Blair, S., Grillo, B., Jones, K., Monasterio, E., Barrett-Adair, M., Clift, J., Feliciano, C., Young, R., Rose, K., Webster, R., Wicks, S., Chen, L., Kennedy, C., Deliz, B., Espada, S., Fuste, P., Luciano, C., Beneggi, M., Capone, L., Molteni, A., Morettini, V., Gupta, A., McNeil, R., Erickson, A., Margolis, M., Naughton, C., Parry, G. J., Walk, D., Arrieta, A., Bartley, N., Canelos, P., Casper, R., Cnaan, A., Duong, T., Hu, F., Sund, Z. & Zimmerman, A., Aug 1 2014, In : Muscle and Nerve. 50, 2, p. 250-256 7 p.

Research output: Contribution to journalArticle

Duchenne Muscular Dystrophy
Natural History
Cardiomyopathies
Research
Therapeutics
18 Citations (Scopus)
H-Reflex
Motor Neurons
Skin
Median Nerve
Reflex
1 Citation (Scopus)

Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies

on Behalf of the PRIMA Trial Investigators and the PATH Study Group, Mar 2019, In : Journal of the Peripheral Nervous System. 24, 1, p. 48-55 8 p.

Research output: Contribution to journalArticle

Open Access
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Polyneuropathies
Intravenous Immunoglobulins
Safety
Drug-Related Side Effects and Adverse Reactions
21 Citations (Scopus)

Gastric mucosal nerve density: A biomarker for diabetic autonomic neuropathy?

Selim, M. M., Wendelschafer-Crabb, G., Redmon, B. B., Khoruts, A., Hodges, J. S., Koch, K., Walk, D. & Kennedy, W. R., Sep 14 2010, In : Neurology. 75, 11, p. 973-981 9 p.

Research output: Contribution to journalArticle

Diabetic Neuropathies
Stomach
Biomarkers
Biopsy
Gastroparesis
63 Citations (Scopus)

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

ITALSGEN Consortium, Genomic Translation for ALS Care (GTAC) Consortium, ALS Sequencing Consortium, NYGC ALS Consortium, Answer ALS Foundation, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, SLAGEN Consortium, French ALS Consortium & Project MinE ALS Sequencing Consortium, Mar 21 2018, In : Neuron. 97, 6, p. 1268-1283.e6

Research output: Contribution to journalArticle

Open Access
Kinesin
Genome
Mutation
Genes
Genome-Wide Association Study
1 Citation (Scopus)

Guillain-Barre syndrome

Walk, D., Jan 1 1997, In : Surgical neurology. 47, 3, p. 305-307 3 p.

Research output: Contribution to journalArticle

Polyradiculoneuropathy
Guillain-Barre Syndrome
Intravenous Immunoglobulins
Autoimmunity
Differential Diagnosis
46 Citations (Scopus)

High-frequency chest wall oscillation in ALS: An exploratory randomized, controlled trial

Lange, D. J., Lechtzin, N., Davey, C., David, W., Heiman-Patterson, T., Gelinas, D., Becker, B. & Mitsumoto, H., Sep 1 2006, In : Neurology. 67, 6, p. 991-997 7 p.

Research output: Contribution to journalArticle

Chest Wall Oscillation
Randomized Controlled Trials
Vital Capacity
Dyspnea
Fatigue
23 Citations (Scopus)
Leukoencephalopathies
Methylenetetrahydrofolate Reductase (NADPH2)
Neural Conduction
Brain Diseases
Methylenetetrahydrofolate reductase deficiency
5 Citations (Scopus)

Late occurrence of chronic immune-mediated axonal polyneuropathy following bone marrow transplant for juvenile-onset α-mannosidosis

Mulrooney, D. A., Davies, S. M., Walk, D. & Charnas, L. R., Nov 1 2003, In : Bone marrow transplantation. 32, 9, p. 953-955 3 p.

Research output: Contribution to journalArticle

Mannosidase Deficiency Diseases
Polyneuropathies
Graft vs Host Disease
Plasma Exchange
Bone Marrow
15 Citations (Scopus)

Mononeuropathy multiplex due to infiltration of lymphoma in hematologic remission

Walk, D., Handelsman, A., Beckmann, E., Kozloff, M. & Shapiro, C., Jun 11 1998, In : Muscle and Nerve. 21, 6, p. 823-826 4 p.

Research output: Contribution to journalArticle

Mononeuropathies
Lymphoma
Femoral Nerve
Peripheral Nerves
Autopsy
61 Citations (Scopus)

Morphological features of nerves in skin biopsies

Wendelschafer-Crabb, G., Kennedy, W. R. & Walk, D., Mar 15 2006, In : Journal of the Neurological Sciences. 242, 1-2 SPEC. ISS., p. 15-21 7 p.

Research output: Contribution to journalArticle

Biopsy
Skin
Axons
Peripheral Nerves
Small Fiber Neuropathy
1 Citation (Scopus)
Amyotrophic Lateral Sclerosis
Motor Cortex
Upper Extremity
Pons
Disease Progression
35 Citations (Scopus)

Phenotypic variability of childhood Charcot-Marie-Tooth disease

Cornett, K. M. D., Menezes, M. P., Bray, P., Halaki, M., Shy, R. R., Yum, S. W., Estilow, T., Moroni, I., Foscan, M., Pagliano, E., Pareyson, D., Laurá, M., Bhandari, T., Muntoni, F., Reilly, M. M., Finkel, R. S., Sowden, J., Eichinger, K. J., Herrmann, D. N., Shy, M. E. & 18 others, Burns, J., Scherer, S., Züchner, S., Saporta, M., Lloyd, T., Li, J., Weiss, M. D., Fischbeck, K., Day, J., Baloh, R., Lewis, R. A., Fridman, V., Ramchandren, S., Walk, D., Johnson, N., Acsadi, G., Baets, J. & Krischer, J., Jun 2016, In : JAMA Neurology. 73, 6, p. 645-651 7 p.

Research output: Contribution to journalArticle

Charcot-Marie-Tooth Disease
Pediatrics
Hand Strength
Ankle
Outcome Assessment (Health Care)
58 Citations (Scopus)

Positive neuropathic sensory symptoms as endpoints in diabetic neuropathy trials

Apfel, S. C., Asbury, A. K., Bril, V., Bruns, T. M., Campbell, J. N., Chalk, C. H., Dyck, P. J., Dyck, P. J. B., Feldman, E. L., Fields, H. L., Grant, I. A., Griffin, J. W., Klein, C. J., Lindblom, U., Litchy, W. J., Low, P. A., Melanson, M., Mendell, J. R., Merren, M. D., O’Brien, P. C. & 10 others, Rendell, M., Rizza, R. A., Service, F. J., Thomas, P. K., Walk, D., Wang, A. K., Wessel, K., Windebank, A. J., Ziegler, D. & Zochodne, D. W., Aug 15 2001, In : Journal of the Neurological Sciences. 189, 1-2, p. 3-5 3 p.

Research output: Contribution to journalArticle

Sensation Disorders
Endpoint Determination
Diabetic Neuropathies
Diabetes Mellitus
Clinical Trials
13 Citations (Scopus)

Rapid resolution of quadriplegic CIDP by combined plasmapheresis and IVIg

Walk, D., Li, L. Y. J., Parry, G. J. & Day, J. W., Jan 13 2004, In : Neurology. 62, 1, p. 155-156 2 p.

Research output: Contribution to journalArticle

Drug Administration Schedule
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Remission Induction
Sural Nerve
Quadriplegia
1 Citation (Scopus)
Open Access
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Polyneuropathies
Intravenous Immunoglobulins
Random Allocation
Therapeutics
36 Citations (Scopus)

Somatosensory evoked potentials in the evaluation of lumbosacral radiculopathy

Walk, D., Fisher, M. A., Doundoulakis, S. H. & Hemmati, M., Jan 1 1992, In : Neurology. 42, 6, p. 1197-1202 6 p.

Research output: Contribution to journalArticle

Radiculopathy
Somatosensory Evoked Potentials
Myelography
Spinal Stenosis
Signs and Symptoms
51 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Immunoglobulins
Placebos
Therapeutics
Intravenous Immunoglobulins
10 Citations (Scopus)

Symptom duration and clinical features in painful sensory neuropathy with and without nerve conduction abnormalities

Walk, D., Zaretskaya, M. & Parry, G. J., Oct 15 2003, In : Journal of the Neurological Sciences. 214, 1-2, p. 3-6 4 p.

Research output: Contribution to journalArticle

Neural Conduction
Polyneuropathies
Nerve Fibers
Signs and Symptoms
Axons
24 Citations (Scopus)

Technology review: The Neurometer® Current Perception Threshold (CPT)

Baquis, G. D., Brown, W. F., Capell, J. T., Chaudhry, V., Cros, D., Drexinger, B. R., Gelblum, J. B., Gilchrist, J. M., Gitter, A. J., Haig, A. J., Hening, W. A., Isaacs, K. H. Z., Lachance, D. H., Magnuson, R. L., Ravits, J. M., Rechtien, J., Sciortino, J. J., Selwa, J. F., Shields, R. W., Spitzer, A. R. & 2 others, Vincent, F. M. & Walk, D., 1999, In : Muscle and Nerve. 22, 4, p. 523-531 9 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

The ALSSQOL: Balancing physical and nonphysical factors in assessing quality of life in ALS

Simmons, Z., Felgoise, S. H., Bremer, B. A., Walsh, S. M., Hufford, D. J., Bromberg, M. B., David, W., Forshew, D. A., Heiman-Patterson, T. D., Lai, E. C. & McCluskey, L., Nov 1 2006, In : Neurology. 67, 9, p. 1659-1664 6 p.

Research output: Contribution to journalArticle

Quality of Life
Psychometrics
Spirituality
Validation Studies
Multicenter Studies
110 Citations (Scopus)
Duchenne Muscular Dystrophy
Natural History
Glucocorticoids
Disease Progression
Outcome Assessment (Health Care)
73 Citations (Scopus)
Duchenne Muscular Dystrophy
Natural History
Glucocorticoids
Longitudinal Studies
Research
4 Citations (Scopus)

Truncating SLC5A7 mutations underlie a spectrum of dominant hereditary motor neuropathies

Salter, C. G., Beijer, D., Hardy, H., Barwick, K. E. S., Bower, M., Mademan, I., De Jonghe, P., Deconinck, T., Russell, M. A., McEntagart, M. M., Chioza, B. A., Blakely, R. D., Chilton, J. K., De Bleecker, J., Baets, J., Baple, E. L., Walk, D. & Crosby, A. H., Apr 1 2018, In : Neurology: Genetics. 4, 2, e222.

Research output: Contribution to journalArticle

Mutation
Frameshift Mutation
Exons
Vocal Cord Paralysis
Inborn Genetic Diseases
9 Citations (Scopus)

Ultra-High Field Proton MR Spectroscopy in Early-Stage Amyotrophic Lateral Sclerosis

Cheong, I., Marjanska, M., Deelchand, D. K., Eberly, L. E., Walk, D. & Oz, G., Jun 1 2017, In : Neurochemical Research. 42, 6, p. 1833-1844 12 p.

Research output: Contribution to journalArticle

Open Access
Amyotrophic Lateral Sclerosis
Inositol
Protons
Magnetic Resonance Spectroscopy
Spectroscopy
233 Citations (Scopus)

Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus

Backonja, M. M., Attal, N., Baron, R., Bouhassira, D., Drangholt, M., Dyck, P. J., Edwards, R. R., Freeman, R., Gracely, R., Haanpaa, M. H., Hansson, P., Hatem, S. M., Krumova, E. K., Jensen, T. S., Maier, C., Mick, G., Rice, A. S., Rolke, R., Treede, R. D., Serra, J. & 7 others, Toelle, T., Tugnoli, V., Walk, D., Walalce, M. S., Ware, M., Yarnitsky, D. & Ziegler, D., Jan 1 2013, In : Pain. 154, 9, p. 1807-1819 13 p.

Research output: Contribution to journalArticle

Somatoform Disorders
Hyperalgesia
Nervous System Diseases
Consensus
Pain Measurement
6 Citations (Scopus)

Western ALS study group

Miller, R. G., Moore, D. H., Jackson, C. E., Gelinas, D., Barohn, R. J., McVey, A., Dick, A., Saperstein, D., Rosenfeld, J., Bromberg, M., Petajan, J., Ravits, J., Kasarskis, E., Neville, H., Ringel, S., Quan, D., Mandler, R., Bosch, E. P., Smith, B., Ross, M. & 24 others, Graves, M., Genge, A., Lomen-Hoerth, C., Olney, R. K., Pestronk, A., Gordon, P. H., Walk, D., Day, J., Parry, G. J., Lou, J. S., Eisen, A., Miller, T. M., Cwik, V., McCluskey, L., Elman, L., Kclkar, P., Bertorini, T., McGrath, M. S., Elliott, J., Tennore, R., Festoff, B. W., Beckman, J. S., Flax, J. & Stephan, D., Sep 1 2004, In : Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 5, SUPPL. 1, p. 121-124 4 p.

Research output: Contribution to journalArticle