David H McKenna, Jr

Projects

Projects per year 1997 2010 2017 2018 2019 2024

• 6 Active
• 35 Finished

Projects per year

Search results

• Active

  Multicomponent solutions for the preservation of cell therapy products

  Hubel, A., Dosa, P. I., Dutton, J. R., McKenna, D. H. & Ogle, B. M.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  7/1/20 → 6/30/24

  Project: Research project

  • therapy 100%
  • product 45%

• Preclinical Studies in Pluripotent Stem Cell-Derived Myogenic Progenitors to Enable a First-in-Human Phase 1 Safety/Dose Escalation Trial for Duchenne Muscular Dystrophy

  Perlingeiro, R., Karachunski, P. I., McKenna, D. H., Schumacher, R. J. & Wagner, J. E.

  DUCHENNE UK

  9/15/19 → 3/31/23

  Project: Research project

  • stem cells 100%
  • safety 69%
  • dosage 47%

• Stem Cells for Treating Acute Stroke

  Low, W. C., Grande, A. W., Hubel, A., Jagadeesan, B. D. & McKenna, D. H.

  Saneron CCEL Therapeutics, Inc.

  9/15/19 → 2/28/23

  Project: Research project

  • Stem Cells 100%
  • Stroke 92%

• Cancer Center Support Grant

  Yee, D., AbuSalah, A. M., Basu, S., Beckman, K. B., Bielinsky, A. K., Cooley, S. A., De For, T. E., Falconer, S. N., Felices, M., Griffin, T. J., Hallstrom, T. C., Hatsukami, D. K., Hendrickson, E. A., Hirsch, B. A., Joseph, A. M., Kirstein, M. N., Konety, B. R., Koopmeiners, J., Kuntz, K. M., Lange, C. A., Largaespada, D. A., Le, C. T., LeBeau, A., Lindgren, B. R., Luo, X., Mc Carthy, J. B., McKenna, D. H., Miller, J. S., Moriarity, B. S., Nelson, H. H., O'Sullivan, G., Ondrey, F. G., Pennell, C. A., Petersen, A. J., Peterson, L. A., Peterson, B. A., Sarver, A. L., Shimizu, Y., Siegfried, J. M., Temiz, N. A., Turesky, R., Vogel, R., Wagner, J. E., Wang, J., Weigel, B. J., Weisdorf, D. J., Woo, J. & Yamamoto, M.

  NIH NATIONAL CANCER INSTITUTE (NCI)

  2/1/19 → 1/31/24

  Project: Research project

• Immusoft Tech Transfer

  McKenna, D. H.

  IMMUSOFT CORPORATION

  9/10/18 → 6/30/22

  Project: Research project

• Biology and Transplantation of the Hematopoietic Stem Cell

  Wagner, J. E., Blazar, B. R., Brunstein, C. G., Cooley, S. A., De For, T. E., Hippen, K. L., Le, C. T., Lindgren, B. R., Luo, X., McKenna, D. H., Miller, J. S., Pennell, C. A., Stefanski, H. E. & Tolar, J.

  NIH NATIONAL CANCER INSTITUTE (NCI)

  9/25/15 → 8/31/22

  Project: Research project

  • Hematopoietic Stem Cell Transplantation 100%
• Finished

  PACT III Manufacture of MSCs for the STAT trial (COVID)

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  7/1/20 → 12/31/20

  Project: Research project

• PACT - Preclinical development of PB-drevived iTregs

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  11/1/19 → 3/31/22

  Project: Research project

• A Clinical Indications Prediction (CLIP) Scale for Human Mesenchymal Stem Cells

  McKenna, D. H.

  SCRIPPS RESEARCH INSTITUTE DBA CALIBR

  9/1/19 → 8/31/21

  Project: Research project

  • Stem cells 100%

• iNK research, SOW8

  McKenna, D. H.

  Fate Therapeutics

  7/1/19 → 3/31/22

  Project: Research project

• Intima process qualification TILs

  McKenna, D. H.

  INTIMA BIOSCIENCES, INC

  5/15/19 → 12/31/21

  Project: Research project

• iNK research, SOW7, feeder line production

  McKenna, D. H.

  Fate Therapeutics

  1/1/19 → 12/31/19

  Project: Research project

• CD133-Targeted Natural Killer Cell Therapy for Aggressive Variant Prostate Cancer

  LeBeau, A., De For, T. E., Gupta, S., McKenna, D. H., Moriarity, B. S. & Webber, B. R.

  Prostate Cancer Foundation

  12/31/18 → 4/30/21

  Project: Research project

  • Cell- and Tissue-Based Therapy 100%
  • Natural Killer Cells 97%
  • Prostatic Neoplasms 83%

• PACT Cryopreservation Technical Study

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  12/3/18 → 12/15/20

  Project: Research project

  • Cryopreservation 100%

• LOVO PACT Center Study

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  9/14/18 → 9/13/19

  Project: Research project

• MGTA 456 Training

  McKenna, D. H.

  MAGENTA THERAPEUTICS

  9/1/18 → 12/31/20

  Project: Research project

• PACT Human Dermal Fibroblast HCB and Decellularized Tiss

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  4/16/18 → 3/31/22

  Project: Research project

  • Fibroblasts 100%
  • Tissue 29%

• PACT III - Peripheral Blood-derived T-regulatory Cells

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  3/22/18 → 3/31/22

  Project: Research project

  • Regulatory T-Lymphocytes 100%

• MD160035: Scalability and Safety Studies

  Perlingeiro, R., Magli, A., McKenna, D. H., Incitti, T. & Kiley, J. D.

  U.S. DEPARTMENT OF DEFENSE

  9/30/17 → 9/29/20

  Project: Research project

  • Safety 100%
  • Clinical Studies 59%
  • Therapeutics 14%

• Multicomponent solutions for the preservation of cell th

  Hubel, A., Dosa, P. I., Dutton, J. R. & McKenna, D. H.

  NIH NATL INST OF BIOMEDICAL IM

  8/3/17 → 4/30/21

  Project: Research project

  • therapy 100%
  • product 45%

• Magenta production preclinical

  McKenna, D. H.

  MAGENTA THERAPEUTICS

  7/1/17 → 10/31/18

  Project: Research project

• Induced NK Cell Therapeutics Manufacturing - preclinical

  McKenna, D. H.

  Fate Therapeutics

  6/19/17 → 12/31/18

  Project: Research project

  • manufacturing 100%
  • cells 64%

• PACT III Task Order PCT0002-01: UCB Derived T Regulatory

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  6/6/17 → 7/16/18

  Project: Research project

• Intima pre-production / validation

  McKenna, D. H.

  INTIMA BIOSCIENCES, INC

  1/1/17 → 6/30/17

  Project: Research project

• Production Assistance for Cellular Therapies (PACT) - Ce

  McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  8/1/16 → 6/30/21

  Project: Research project

• Fate Therapeutics MCT development/validation

  McKenna, D. H.

  Fate Therapeutics

  6/22/16 → 6/30/19

  Project: Research project

  • Therapeutics 100%

• Integrated training in development and clinical practice

  Hubel, A. & McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  8/15/15 → 5/31/21

  Project: Research project

  • Cell- and Tissue-Based Therapy 100%

• Technology platform for development of multi-component p

  Hubel, A., Dosa, P. I., McKenna, D. H. & Sachs, J. N.

  NIH NATL INST OF BIOMEDICAL IM

  8/1/13 → 7/31/16

  Project: Research project

• Post thaw assessment of umbilical cord blood

  Hubel, A. & McKenna, D. H.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  4/15/12 → 3/31/15

  Project: Research project

  • umbilical cord 100%
  • blood 43%

• First in human, single arm, single center, open-label

  Wagner, J. E., Brunstein, C. G. & McKenna, D. H.

  NOVARTIS PHARMACEUTICALS CORPORATION

  8/1/11 → 11/2/16

  Project: Research project

  • Proof of Concept Study 100%
  • Hematologic Neoplasms 81%
  • Hematopoietic Stem Cells 79%
  • Fetal Blood 78%
  • Safety 46%

• Stem Cell Priming to Enhance Engraftment

  Brunstein, C. G., McKenna, D. H. & Wagner, J. E.

  University of Virginia

  9/3/10 → 8/31/12

  Project: Research project

• NHLBI Production Assistance for Cellular Therapies (PACT

  Wagner, J. E., Curtsinger, J. M., Hippen, K. L., Mc Cullough, J., McKenna, D. H., Miller, J. S. & Orchard, P. J.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  1/15/10 → 1/14/15

  Project: Research project

• Task 2: Development and Validation of LFU835 HPSC GMP

  Wagner, J. E., Blazar, B. R., Brunstein, C. G., McKenna, D. H. & Tolar, J.

  NOVARTISPHARMACEUTICALS CORPORATION

  1/4/10 → 11/23/11

  Project: Research project

• Task 1: Development and Validation of LFU835 HPSC GMP

  Wagner, J. E., Blazar, B. R., Brunstein, C. G., McKenna, D. H. & Tolar, J.

  NOVARTIS PHARMACEUTICALS CORPORATION

  1/4/10 → 10/31/10

  Project: Research project

• Stem Cell Priming to Enhance Engraftment

  Brunstein, C. G., McKenna, D. H. & Wagner, J. E.

  Case Western Reserve University

  9/30/09 → 8/31/10

  Project: Research project

• Optimization of Cell Culture Conditions

  McKenna, D. H.

  MN MED FDN

  12/10/07 → 12/9/09

  Project: Research project

  • Cell culture 100%

• MN Cardiovascular Cell Therapy Clinical Research Network

  Henry, T. D., McKenna, D. H. & Taylor, D. A.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  1/1/07 → 2/29/12

  Project: Research project

  • Cell- and Tissue-Based Therapy 100%

• Multi-lineage Progenitor Cells: Airway Differentiation a

  McKenna, D. H.

  BioE Inc.

  7/1/06 → 12/31/10

  Project: Research project

  • Cell Differentiation 100%
  • Stem Cells 90%

• Cell Graft Engineering using Microfluids

  Hubel, A., Longmire, E. K. & McKenna, D. H.

  NIH NATL INST OF BIOMEDICAL IM

  2/1/06 → 1/31/09

  Project: Research project

  • engineering 100%
  • cells 72%

• Evaluation of the Safety of Repeated Autologous Infusion

  Mc Cullough, J., Eastlund, D., McKenna, D. H. & Steiner, M. E.

  ZYMEQUEST, INC

  2/1/06 → 12/31/08

  Project: Research project

  • Enzymes 100%
  • Cells 84%

• Biology and Transplantation of the Human Stem Cell

  Mc Glave, P. B., Blazar, B. R., Ekker, S. C., Kaufman, D. S., Le, C. T., McKenna, D. H., Miller, J. S. & Wagner, J. E.

  NIH NATIONAL CANCER INSTITUTE (NCI)

  9/15/97 → 7/1/10

  Project: Research project

  • Stem Cell Transplantation 100%