Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Targeting the Myosin Essential Light Chain to Tune Cardiac Contractility
Guhathakurta, P. (PI), Thomas, D. D. (Consultant/Collaborator), Thompson, A. R. (Other Role) & Yuen, S. L. (Other Role)
AMERICAN HEART ASSOCIATION, INC
7/1/26 → 6/30/28
Project: Research project
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Calmodulin and regulation of Cardiac Ryanodine Receptor and CaMKII
Rebbeck, R. T. (PI), Aldrich, C. (CoI), Svensson, B. (CoI), Thomas, D. D. (CoI), Solberg, J. C. (Other Role) & Yuen, S. L. (Other Role)
UNIVERSITY OF CALIFORNIA, DAVIS, NIH NATL HEART, LUNG AND BLOOD INSTITU
1/1/25 → 11/30/28
Project: Research project
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Protein structural biophysics driving drug discovery for cardiac calcium transport regulation, producing translational advances and mechanistic insights
Aldrich, C. (PI), Gurvich, V. J. (PI), Thomas, D. D. (PI) & Rebbeck, R. T. (CoI)
NIH NATL HEART, LUNG AND BLOOD INSTITU
5/1/24 → 4/30/28
Project: Research project
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Structural and dynamic basis for PRKACA-dependent signalopathies
Veglia, G. (PI) & Thomas, D. D. (CoI)
4/1/24 → 3/31/29
Project: Research project
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Skeletal muscle protein structural dynamics and function drive applications to drug discovery
Aldrich, C. (PI), Gurvich, V. J. (PI), Lowe, D. A. (PI), Thomas, D. D. (PI), Cornea, R. L. (CoI) & Rebbeck, R. T. (Co-Principal Investigator)
NIH NIAMS NATIONALL INSTITUTE OF ARTHRIT
5/1/23 → 4/30/28
Project: Research project
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A piperidinyl amide compound enhances Ca2+ signaling in cardiomyocytes by increasing activity of Ca2+ pump
Bovo, E., Nikolaienko, R., Yuen, S. L., Makarewich, C. A., Brinkmann, M., Thomas, D. D., Rebbeck, R. T. & Zima, A. V., Mar 11 2026, In: Biophysical Reports. 6, 1, 100250.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Development of activators for SERCA2a for heart failure treatments
Brinkmann, M., Wong, T. Y., Roopnarine, O., Yuen, S. L., Berg, K., Cornea, R. L., Rebbeck, R. T., Thomas, D. D. & Aldrich, C. C., Feb 5 2026, In: European Journal of Medicinal Chemistry. 303, 118408.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Large-scale high-throughput screen for cardiac ryanodine receptor targeted therapeutics
Nikolaienko, R., Bovo, E., Solberg, J. C., Brinkmann, M., Treinen, L. M., Thompson, A. R., Berg, K., Thomas, D. D., Thomas, J. J., Bers, D. M., Aldrich, C. C., Zima, A. V., Cornea, R. L. & Rebbeck, R. T., Jan 2026, In: Journal of Biological Chemistry. 302, 1, 110951.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Roger Cooke (1940–2024): a legacy in muscle biophysics and molecular motors
dos Remedios, C., Thomas, D. D. & Li, A., Jun 2026, In: Biophysical Reviews. 18, 3, p. 565-567 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
A FRET assay to monitor different structural states of human β-cardiac myosin including the interacting-heads motif
Goluguri, R. R., Guhathakurta, P., Nandwani, N., Dawood, A., Yokota, S., Roopnarine, O., Thomas, D. D., Ruppel, K. M. & Spudich, J. A., Aug 26 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 34, e2504562122.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Scopus citations
Datasets
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Ensembles from dynamic refinement of non-phosphorylated and phosphorylated phospholamban-SERCA complex
Weber, D. K., Sanz-Hernández, M., Uddigiri, V. R., Wang, S., Larsen, E., Tata, G., Gustavsson, M., Cornea, R. L., Thomas, D. D., De Simone, A. & Veglia, G., Data Repository for the University of Minnesota, 2021
DOI: 10.13020/bkja-jq93, http://hdl.handle.net/11299/218010
Dataset