Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Protein structural biophysics driving drug discovery for cardiac calcium transport regulation, producing translational advances and mechanistic insights
Thomas, D. D. (PI), Aldrich, C. (CoI) & Rebbeck, R. T. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/24 → 4/30/29
Project: Research project
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Structural and dynamic basis for PRKACA-dependent signalopathies
Veglia, G. (PI) & Thomas, D. D. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
4/1/24 → 3/31/29
Project: Research project
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Skeletal muscle protein structural dynamics and function drive applications to drug discovery
Thomas, D. D. (PI), Cornea, R. L. (CoI), Lowe, D. A. (CoI) & Rebbeck, R. T. (Co-Principal Investigator)
NIH NIAMS NATL INST OF ARTHRIT
5/1/23 → 4/30/28
Project: Research project
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Minnesota Muscle Training Program
Thomas, D. D. (PI)
NIH NIAMS NATL INST OF ARTHRIT
5/1/22 → 4/30/27
Project: Research project
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Structural Dynamics of Muscle Calcium ATPase Regulation
Thomas, D. D. (PI), Aihara, H. (CoI), Cornea, R. L. (Co-Principal Investigator) & Aldrich, C. (Consultant/Collaborator)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/20 → 4/30/24
Project: Research project
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Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors
Rasmussen, D. M., Semonis, M. M., Greene, J. T., Muretta, J. M., Thompson, A. R., Toledo Ramos, S., Thomas, D. D., Pomerantz, W. C. K., Freedman, T. S. & Levinson, N. M., May 14 2024, In: eLife. 13, 13:RP95481.Research output: Contribution to journal › Article › peer-review
Open Access -
Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors
Rebbeck, R. T., Svensson, B., Zhang, J., Samsó, M., Thomas, D. D., Bers, D. M. & Cornea, R. L., Dec 2024, In: Nature communications. 15, 1, 5120.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural Dynamics of Protein Interactions Using Site-Directed Spin Labeling of Cysteines to Measure Distances and Rotational Dynamics with EPR Spectroscopy
Roopnarine, O. & Thomas, D. D., Mar 2024, In: Applied Magnetic Resonance. 55, 1-3, p. 79-100 22 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein
Braun, A. R., Kochen, N. N., Yuen, S. L., Liao, E. E., Cornea, R. L., Thomas, D. D. & Sachs, J. N., Jan 1 2023, In: ASN Neuro. 15Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation
Ernst, P., Bidwell, P. A., Dora, M., Thomas, D. D. & Kamdar, F., Jan 18 2023, In: Frontiers in Cell and Developmental Biology. 10, 986107.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations
Datasets
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Ensembles from dynamic refinement of non-phosphorylated and phosphorylated phospholamban-SERCA complex
Weber, D. K., Sanz-Hernández, M., Uddigiri, V. R., Wang, S., Larsen, E., Tata, G., Gustavsson, M., Cornea, R. L., Thomas, D. D., De Simone, A. & Veglia, G., Data Repository for the University of Minnesota, 2021
DOI: 10.13020/bkja-jq93, http://hdl.handle.net/11299/218010
Dataset