Projects per year
Personal profile
Expertise related to UN SDGs
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Projects
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Structural Dynamics of Muscle Calcium ATPase Regulation
Thomas, D. D., Aihara, H. & Cornea, R. L.
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/20 → 4/30/24
Project: Research project
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Time-resolved FRET-based allostery sensors for any protein kinase drug target
Levinson, N. M., Drake, J. M., Georg, G. & Thomas, D. D.
NIH NATIONAL CANCER INSTITUTE (NCI)
3/1/20 → 2/28/23
Project: Research project
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Drug discovery for spinocerebellar ataxia, using novel fluorescence technology targeting B-III-spectrin
Hays, T. S., Avery, A. & Thomas, D. D.
NIH NAT INST OF NEURO DISORDERS & STROKE
5/1/19 → 4/30/22
Project: Research project
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Mechanisms that Regulate Intracellular Transport
Hays, T. S., Parker, L. L. & Thomas, D. D.
NIH NIGMS NATL INST OF GENERAL
5/1/19 → 1/31/23
Project: Research project
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Structural Basis of Dilated Cardiomyopathy
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
7/1/18 → 6/30/22
Project: Research project
Research output
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Allostery governs Cdk2 activation and differential recognition of CDK inhibitors
Majumdar, A., Burban, D., Muretta, J. M., Thompson, A. R., Engel, T. A., Rasmussen, D. M., Subrahmanian, M. V., Veglia, G., Thomas, D. D. & Levinson, N. M., 2021, (Accepted/In press) In: Nature Chemical Biology.Research output: Contribution to journal › Article › peer-review
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Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators
Lo, C. H., Schaaf, T. M., Thomas, D. D. & Sachs, J. N., 2021, Methods in Molecular Biology. Humana Press Inc., p. 121-137 17 p. (Methods in Molecular Biology; vol. 2248).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac muscle
Guhathakurta, P., Phung, L. A., Prochniewicz, E., Lichtenberger, S., Wilson, A. & Thomas, D. D., Oct 9 2020, In: Journal of Biological Chemistry. 295, 41, p. 14100-14110 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells
Lo, C. H., Pandey, N. K., Lim, C. K. W., Ding, Z., Tao, M., Thomas, D. D., Langen, R. & Sachs, J. N., Aug 5 2020, In: ACS Chemical Neuroscience. 11, 15, p. 2286-2295 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V
Gunther, L. K., Rohde, J. A., Tang, W., Cirilo, J. A., Marang, C. P., Scott, B. D., Thomas, D. D., Debold, E. P. & Yengo, C. M., Dec 18 2020, In: Journal of Biological Chemistry. 295, 51, p. 17383-17397 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations
Datasets
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Ensembles from dynamic refinement of non-phosphorylated and phosphorylated phospholamban-SERCA complex
Weber, D. K., Sanz-Hernández, M., Uddigiri, V. R., Wang, S., Larsen, E. K., Tata, G., Gustavsson, M., Cornea, R. L., Thomas, D. D., De Simone, A. & Veglia, G., Data Repository for the University of Minnesota, 2021
DOI: 10.13020/bkja-jq93, http://hdl.handle.net/11299/218010
Dataset