David A Largaespada

Accepting PhD Students

1990 …2024
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1990 2019

Filter
Letter
2016
4 Citations (Scopus)

Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the wnt pathway, as potential targets in del(5q) myeloid neoplasms

Stoddart, A., Qian, Z., Fernald, A. A., Bergerson, R. J., Wang, J., Karrison, T., Anastasi, J., Bartom, E. T., Sarver, A. L., McNerney, M. E., Largaespada, D. A. & Le Beau, M. M., May 31 2016, In : Haematologica. 101, 6, p. e232-e236

Research output: Contribution to journalLetter

Wnt Signaling Pathway
Insertional Mutagenesis
Genes
Neoplasms
2010
14 Citations (Scopus)

Deoxycytidine kinase is downregulated in Ara-C-resistant acute myeloid leukemia murine cell lines

Rathe, S. & Largaespada, D. A., Jan 1 2010, In : Leukemia. 24, 8, p. 1513-1515 3 p.

Research output: Contribution to journalLetter

Antineoplastic Antimetabolites
Neoplasm Drug Resistance
Deoxycytidine Kinase
Cytarabine
Tumor Cell Line
2007
13 Citations (Scopus)

A microarray study of altered gene expression after cytarabine resistance in acute myeloid leukemia [3]

Yin, B., Tsai, M. L., Hasz, D. E., Rathe, S., Le Beau, M. M. & Largaespada, D. A., Jan 1 2007, In : Leukemia. 21, 5, p. 1093-1097 5 p.

Research output: Contribution to journalLetter

Antineoplastic Antimetabolites
Neoplasm Drug Resistance
Proto-Oncogene Proteins c-bcl-2
DNA Mismatch Repair
Amyloid beta-Protein Precursor
2006
20 Citations (Scopus)

Nf1 gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways [9]

Yin, B., Morgan, K., Hasz, D. E., Mao, Z. & Largaespada, D. A., Jan 1 2006, In : Leukemia. 20, 1, p. 151-154 4 p.

Research output: Contribution to journalLetter

Neoplasm Drug Resistance
Neurofibromatosis 1 Genes
Neurofibromin 1
Myeloid Leukemia
Cytarabine