David A Largaespada

Accepting PhD Students

1990 …2024
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Research Output 1990 2020


Erratum: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma (Nature (2012) 486 (266-270) DOI: 10.1038/nature11114)

Pérez-Mancera, P. A., Rust, A. G., Van Der Weyden, L., Kristiansen, G., Li, A., Sarver, A. L., Silverstein, K. A. T., Grützmann, R., Aust, D., Rümmele, P., Knösel, T., Herd, C., Stemple, D. L., Kettleborough, R., Brosnan, J. A., Li, A., Morgan, R., Knight, S., Yu, J., Stegeman, S. & 17 others, Collier, L. S., Ten Hoeve, J. J., De Ridder, J., Klein, A. P., Goggins, M., Hruban, R. H., Chang, D. K., Biankin, A. V., Grimmond, S. M., Initiative, A. P. C. G., Wessels, L. F. A., Wood, S. A., Iacobuzio-Donahue, C. A., Pilarsky, C., Largaespada, D. A., Adams, D. J. & Tuveson, D. A., Feb 21 2013, In : Nature. 494, 7437, 1 p.

Research output: Contribution to journalComment/debate

Deubiquitinating Enzymes

Retrotransposons: A new and credible source of inherited and somatically acquired hepatocellular carcinoma mutations

Rahrmann, E. P. & Largaespada, D. A., Sep 1 2013, In : Journal of Hepatology. 59, 3, p. 616-617 2 p.

Research output: Contribution to journalComment/debate

DNA Mutational Analysis
Long Interspersed Nucleotide Elements
Insertional Mutagenesis
Liver Neoplasms
13 Citations (Scopus)

Why men are at higher risk for hepatocellular carcinoma?

Keng, V. W., Largaespada, D. A. & Villanueva, A., Aug 1 2012, In : Journal of Hepatology. 57, 2, p. 453-454 2 p.

Research output: Contribution to journalComment/debate

Hepatocellular Carcinoma
3 Citations (Scopus)

Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

Varela, I., Tarpey, P., Raine, K., Huang, D., Ong, C. K., Stephens, P., Davies, H., Jones, D., Lin, M. L., Teague, J., Bignell, G., Butler, A., Cho, J., Dalgliesh, G. L., Galappaththige, D., Greenman, C., Hardy, C., Jia, M., Latimer, C., Lau, K. W. & 24 others, Marshall, J., McLaren, S., Menzies, A., Mudie, L., Stebbings, L., Largaespada, D. A., Wessels, L. F., Richard, S., Kahnoski, R. J., Anema, J., Tuveson, D. A., Perez-Mancera, P. A., Mustonen, V., Fischer, A., Adams, D. J., Rust, A., Chan-On, W., Subimerb, C., Dykema, K., Furge, K., Campbell, P. J., Teh, B. T., Stratton, M. R. & Futreal, P. A., Sep 2011, In : Journal of Urology. 186, 3, 1 p.

Research output: Contribution to journalComment/debate


Erratum: A microarray study of altered gene expression in Ara-C resistance in acute myeloid leukemia (Leukemia (2007) 21 (1093-1097))

Yin, B., Tsai, M. L., Hasz, D. E., Rathe, S. K., Lebeau, M. & Largaespada, D. A., Aug 2010, In : Leukemia. 24, 8, 1 p.

Research output: Contribution to journalComment/debate

Acute Myeloid Leukemia
Gene Expression
15 Citations (Scopus)

Erratum: Pluripotency of mesenchymal stem cells derived from adult marrow (Nature (2002) 418 (41-49) DOI: 10.1038/nature00870)

Jiang, Y., Jahagirdar, B. N., Reinhardt, R. L., Schwartz, R. E., Keene, C. D., Ortiz-Gonzalez, X. R., Reyes, M., Lenvik, T., Lund, T., Blackstad, M., Du, J., Aldrich, S., Lisberg, A., Low, W. C., Largaespada, D. A. & Verfaillie, C. M., Jun 14 2007, In : Nature. 447, 7146, p. 879-880 2 p.

Research output: Contribution to journalComment/debate

33 Citations (Scopus)

Haploinsufficiency for tumor suppression: The hazards of being single and living a long time

Largaespada, D. A., Feb 19 2001, In : Journal of Experimental Medicine. 193, 4, p. F15-F18

Research output: Contribution to journalComment/debate

Fusion Oncogene Proteins
Neoplasm Proteins
Proto-Oncogene Proteins c-bcl-2
Neoplastic Cell Transformation