David A Largaespada

Accepting PhD Students

1990 …2024
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Research Output 1990 2020

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Comment/debate
2013

Erratum: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma (Nature (2012) 486 (266-270) DOI: 10.1038/nature11114)

Pérez-Mancera, P. A., Rust, A. G., Van Der Weyden, L., Kristiansen, G., Li, A., Sarver, A. L., Silverstein, K. A. T., Grützmann, R., Aust, D., Rümmele, P., Knösel, T., Herd, C., Stemple, D. L., Kettleborough, R., Brosnan, J. A., Li, A., Morgan, R., Knight, S., Yu, J., Stegeman, S. & 17 others, Collier, L. S., Ten Hoeve, J. J., De Ridder, J., Klein, A. P., Goggins, M., Hruban, R. H., Chang, D. K., Biankin, A. V., Grimmond, S. M., Initiative, A. P. C. G., Wessels, L. F. A., Wood, S. A., Iacobuzio-Donahue, C. A., Pilarsky, C., Largaespada, D. A., Adams, D. J. & Tuveson, D. A., Feb 21 2013, In : Nature. 494, 7437, 1 p.

Research output: Contribution to journalComment/debate

Adenocarcinoma
Deubiquitinating Enzymes

Retrotransposons: A new and credible source of inherited and somatically acquired hepatocellular carcinoma mutations

Rahrmann, E. P. & Largaespada, D. A., Sep 1 2013, In : Journal of Hepatology. 59, 3, p. 616-617 2 p.

Research output: Contribution to journalComment/debate

DNA Mutational Analysis
Long Interspersed Nucleotide Elements
Retroelements
Insertional Mutagenesis
Liver Neoplasms
2012
13 Citations (Scopus)

Why men are at higher risk for hepatocellular carcinoma?

Keng, V. W., Largaespada, D. A. & Villanueva, A., Aug 1 2012, In : Journal of Hepatology. 57, 2, p. 453-454 2 p.

Research output: Contribution to journalComment/debate

Hepatocellular Carcinoma
2011
3 Citations (Scopus)

Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

Varela, I., Tarpey, P., Raine, K., Huang, D., Ong, C. K., Stephens, P., Davies, H., Jones, D., Lin, M. L., Teague, J., Bignell, G., Butler, A., Cho, J., Dalgliesh, G. L., Galappaththige, D., Greenman, C., Hardy, C., Jia, M., Latimer, C., Lau, K. W. & 24 others, Marshall, J., McLaren, S., Menzies, A., Mudie, L., Stebbings, L., Largaespada, D. A., Wessels, L. F., Richard, S., Kahnoski, R. J., Anema, J., Tuveson, D. A., Perez-Mancera, P. A., Mustonen, V., Fischer, A., Adams, D. J., Rust, A., Chan-On, W., Subimerb, C., Dykema, K., Furge, K., Campbell, P. J., Teh, B. T., Stratton, M. R. & Futreal, P. A., Sep 2011, In : Journal of Urology. 186, 3, 1 p.

Research output: Contribution to journalComment/debate

Exome
Carcinoma
Kidney
Mutation
Genes
2010

Erratum: A microarray study of altered gene expression in Ara-C resistance in acute myeloid leukemia (Leukemia (2007) 21 (1093-1097))

Yin, B., Tsai, M. L., Hasz, D. E., Rathe, S. K., Lebeau, M. & Largaespada, D. A., Aug 2010, In : Leukemia. 24, 8, 1 p.

Research output: Contribution to journalComment/debate

Cytarabine
Acute Myeloid Leukemia
Leukemia
Gene Expression
2007
15 Citations (Scopus)

Erratum: Pluripotency of mesenchymal stem cells derived from adult marrow (Nature (2002) 418 (41-49) DOI: 10.1038/nature00870)

Jiang, Y., Jahagirdar, B. N., Reinhardt, R. L., Schwartz, R. E., Keene, C. D., Ortiz-Gonzalez, X. R., Reyes, M., Lenvik, T., Lund, T., Blackstad, M., Du, J., Aldrich, S., Lisberg, A., Low, W. C., Largaespada, D. A. & Verfaillie, C. M., Jun 14 2007, In : Nature. 447, 7146, p. 879-880 2 p.

Research output: Contribution to journalComment/debate

2001
33 Citations (Scopus)

Haploinsufficiency for tumor suppression: The hazards of being single and living a long time

Largaespada, D. A., Feb 19 2001, In : Journal of Experimental Medicine. 193, 4, p. F15-F18

Research output: Contribution to journalComment/debate

Fusion Oncogene Proteins
Neoplasm Proteins
Proto-Oncogene Proteins c-bcl-2
Neoplastic Cell Transformation
Haploinsufficiency