Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 6 Clean Water and Sanitation -
SDG 7 Affordable and Clean Energy -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 16 Peace, Justice and Strong Institutions
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting Medulloblastoma with Multispecific Multivalent T-cell Engagers
Foo, J. Y. (PI), Largaespada, D. A. (PI), Leder, K. Z. (PI), Wagner, C. R. (PI), Zhang, L. (PI), Galvin, R. T. (Other Role), Rozumalski, L. (Other Role) & Seeman, Z. (Other Role)
9/22/26 → 8/31/29
Project: Research project
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HEMO as a Biomarker and Target for Malignant Peripheral Nerve Sheath Tumors (MPNST)
Largaespada, D. A. (PI) & Muretta, J. M. (PI)
7/1/26 → 6/30/28
Project: Research project
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Development of Region-Specific, Immunocompetent Breast Cancer Brain Metastasis Models Using Sleeping Beauty Mutagenesis
Largaespada, D. A. (PI), Rahrmann, E. P. (PI), Temiz, N. A. (PI), Guinovart, D. (CoI), Stehn, C. M. (Graduate Student), Cheng, T. (Other Role) & Qaraad, M. (Other Role)
CONGRESSIONAL DIRECTED MED RSRC PROGRAM
5/1/26 → 4/30/29
Project: Research project
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DAY301
Largaespada, D. A. (PI)
DAY ONE BIOPHARMACEUTICALS, INC
1/14/26 → 1/13/29
Project: Research project
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A Window of Opportunity Trial of Mirdametinib Plus Vorinostat forNF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]
Largaespada, D. A. (PI), Moertel, C. L. (CoI), Murugan, P. (CoI), Ozutemiz, C. (CoI), Williams, K. B. (CoI) & Eaton, A. (Other Role)
9/1/25 → 8/31/27
Project: Research project
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Transposon mutagenesis-guided crispr/cas9 screening strongly implicates dysregulation of hippo/yap signaling in malignant peripheral nerve sheath tumor development
Vélez-Reyes, G. L., Koes, N., Ryu, J. H., Kaufmann, G., Berner, M., Weg, M. T., Wolf, N. K., Rathe, S. K., Ratner, N., Moriarity, B. S. & Largaespada, D. A., Apr 1 2021, In: Cancers. 13, 7, 1584.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
A new framework for engaging patients and the public in basic cancer research
Gandhi, S., Ahmadian, S., Buckle, P., Largaespada, D. A., Aldape, K., Mansouri, S. & Zadeh, G., Mar 2026, In: Nature Reviews Cancer. 26, 3, p. 162-163 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Direct interaction between human DDX1 and SARS-CoV-2 nucleocapsid protein is regulated by phosphorylation
Wang, L., Baxley, R. M., Largaespada, D. A., Aihara, H. & Bielinsky, A. K., May 2026, In: Journal of Biological Chemistry. 302, 5, 111408.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
DNA Hypomethylation Is Not Cell Intrinsically Toxic to Polycomb Repressive Complex 2 Deficient Malignant Peripheral Nerve Sheath Tumors
Stahl, M. R., Stehn, C. M., Seeman, Z. J., Faulk, C. & Largaespada, D. A., Aug 2026, In: Genes Chromosomes and Cancer. 65, 8, e70156.Research output: Contribution to journal › Article › peer-review
Open Access -
Glioblastoma Subtypes Exhibit Distinct Migration Mechanics and Immune Responses
Shamsan, G. A., Liu, C. J., Braman, B. C., Li, R., Rathe, S. K., Sarver, A. L., Ghaderi, N., McMahon, M., Klank, R. L., Tschida, B. R., McFarren, S. J., Rosato, P. C., Masopust, D., Sarkaria, J. N., Clark, H. B., Rosenfeld, S., Largaespada, D. A. & Odde, D. J., 2026, In: Cancer Research Communications. 6, 8, p. 1898-1915 18 p.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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HI’s new chief of staff looking to help build the Institute to even loftier heights
Fedie, E., Bode, A. M., Seabloom, D. E., Voytas, D. F. & Largaespada, D. A.
7/15/20
1 item of Media coverage
Press/Media: Expert Comment or Interview