Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Center for Functional Genomics of Immunotherapy (CFGI)
Largaespada, D. A. (PI), Moriarity, B. S. (CoI) & Stromnes, I. M. (CoI)
3/1/24 → 3/31/26
Project: Research project
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Linking ex vivo to in vivo patient-specific models of malignant peripheral nerve sheath tumors
Wood, D. K. (PI) & Largaespada, D. A. (CoI)
1/1/24 → 12/31/26
Project: Research project
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Leveraging a precision medicine platform to understand drug sensitivities in NF1 and PRC2 deficient malignant peripheral nerve sheath tumors
Largaespada, D. A. (PI)
8/1/23 → 7/31/26
Project: Research project
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Deconvoluting the Ewing sarcoma genetic program using ancestry-informed human iPSC modeling
Webber, B. R. (PI), Dutton, J. R. (CoI), Largaespada, D. A. (CoI) & Spector, L. G. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
4/7/23 → 3/31/28
Project: Research project
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Mechanistic insight into genome stability pathways
Largaespada, D. A. (PI)
UNIVERSITY OF VIRGINIA, NIH NIGMS NATL INST OF GENERAL
11/15/22 → 5/31/26
Project: Research project
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Transposon mutagenesis-guided crispr/cas9 screening strongly implicates dysregulation of hippo/yap signaling in malignant peripheral nerve sheath tumor development
Vélez-Reyes, G. L., Koes, N., Ryu, J. H., Kaufmann, G., Berner, M., Weg, M. T., Wolf, N. K., Rathe, S. K., Ratner, N., Moriarity, B. S. & Largaespada, D. A., Apr 1 2021, In: Cancers. 13, 7, 1584.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance
Fan, J. J., Erickson, A. W., Carrillo-Garcia, J., Wang, X., Skowron, P., Wang, X., Chen, X., Shan, G., Dou, W., Bahrampour, S., Xiong, Y., Dong, W., Abeysundara, N., Francisco, M. A., Pusong, R. J., Wang, W., Li, M., Ying, E., Suárez, R. A. & Farooq, H. & 20 others, , Jun 9 2025, In: Developmental Cell. 60, 11, p. 1532-1549.e7Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Cell Type Specific Suppression of Hyper-Recombination by Human RAD18 Is Linked to Proliferating Cell Nuclear Antigen K164 Ubiquitination
Rogers, C. B., Leung, W., Baxley, R. M., Kram, R. E., Wang, L., Buytendorp, J. P., Le, K., Largaespada, D. A., Hendrickson, E. A. & Bielinsky, A. K., Jan 2025, In: Biomolecules. 15, 1, 150.Research output: Contribution to journal › Article › peer-review
Open Access -
Consensus recommendations for an integrated diagnostic approach to peripheral nerve sheath tumors arising in the setting of Neurofibromatosis Type 1
Symposium on Atypical Neurofbroma: State of the Science Members, Mar 1 2025, In: Neuro-Oncology. 27, 3, p. 616-624 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
DEAPR: Differential Expression and Pathway Ranking Tool Demonstrates NRASG12V and NRASG12D Mutations Have Differing Effects in THP-1 Cells
Rathe, S., White, J. P., Sachs, Z. & Largaespada, D. A., Feb 2025, In: Cancers. 17, 3, 467.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Press/Media
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HI’s new chief of staff looking to help build the Institute to even loftier heights
Fedie, E., Bode, A. M., Seabloom, D. E., Voytas, D. F. & Largaespada, D. A.
7/15/20
1 item of Media coverage
Press/Media: Expert Comment or Interview