19982019
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 11 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Ribonuclease H Medicine & Life Sciences
Biosynthesis Chemical Compounds
Inosine Monophosphate Medicine & Life Sciences
Siderophores Medicine & Life Sciences
HIV Reverse Transcriptase Medicine & Life Sciences
Oxidoreductases Medicine & Life Sciences
Enzymes Medicine & Life Sciences

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Projects 2009 2013

Multidrug-Resistant Tuberculosis
Mycobacterium tuberculosis
Communicable Diseases
Tuberculosis
Mortality

Research Output 1998 2019

1 Citation (Scopus)

Discovery of Irreversible p97 Inhibitors

Ding, R., Zhang, T., Wilson, D. J., Xie, J., Williams, J., Xu, Y., Ye, Y. & Chen, L., Mar 14 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2814-2829 16 p.

Research output: Contribution to journalArticle

Amides
Mutagenesis
Cysteine
Mass Spectrometry
Neoplasms
2 Citations (Scopus)

Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker

Tang, J., Do, H. T., Huber, A. D., Casey, M. C., Kirby, K. A., Wilson, D. J., Kankanala, J., Parniak, M. A., Sarafianos, S. G. & Wang, Z., Mar 15 2019, In : European Journal of Medicinal Chemistry. 166, p. 390-399 10 p.

Research output: Contribution to journalArticle

Ribonuclease H
HIV Reverse Transcriptase
Catalytic Domain
Integrases
RNA-Directed DNA Polymerase
3 Citations (Scopus)

6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity

Wang, L., Tang, J., Huber, A. D., Casey, M. C., Kirby, K. A., Wilson, D. J., Kankanala, J., Xie, J., Parniak, M. A., Sarafianos, S. G. & Wang, Z., Aug 5 2018, In : European Journal of Medicinal Chemistry. 156, p. 652-665 14 p.

Research output: Contribution to journalArticle

Open Access
Ribonuclease H
HIV Reverse Transcriptase
Human Immunodeficiency Virus Ribonuclease H
Antiviral Agents
RNA-Directed DNA Polymerase
4 Citations (Scopus)

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H

Wang, L., Tang, J., Huber, A. D., Casey, M. C., Kirby, K. A., Wilson, D. J., Kankanala, J., Parniak, M. A., Sarafianos, S. G. & Wang, Z., Aug 5 2018, In : European Journal of Medicinal Chemistry. 156, p. 680-691 12 p.

Research output: Contribution to journalArticle

Open Access
Ribonuclease H
HIV Reverse Transcriptase
RNA-Directed DNA Polymerase
Human Immunodeficiency Virus Ribonuclease H
Antiviral Agents
7 Citations (Scopus)

6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase

TANG, JING., Kirby, K. A., Huber, A. D., Casey, M. C., Ji, J., Wilson, D., Sarafianos, S. G. & Wang, Z., Jan 1 2017, In : European Journal of Medicinal Chemistry. 128, p. 168-179 12 p.

Research output: Contribution to journalArticle

Ribonuclease H
DNA-Directed RNA Polymerases
Viruses
Scaffolds
HIV