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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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PROJECT 2 ? CHEMICAL MODULATION OF DNA DEAMINASES IN CANCER
Harki, D. A. (PI)
UT HEALTH SCIENCE CENTER SAN ANTONIO, NATIONAL INSTITUTES OF HEALTH (NIH)
10/7/25 → 1/10/26
Project: Research project
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Novel Protein Degraders for Treating RET Positive Cancer
Drake, J. M. (PI), Harki, D. A. (CoI), Kabir, F. (Graduate Student) & Tengse, S. B. (Graduate Student)
11/1/24 → 10/31/26
Project: Research project
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Cancer Center Support Grant
Miller, J. S. (PI), Antonarakis, E. (CoI), Beckman, K. B. (CoI), Betts, B. (CoI), Blaes, A. H. (CoI), Eaton, A. (CoI), Ellis, K. M. (CoI), Felices, M. (CoI), Geller, M. A. (CoI), Ghebre, R. G. (CoI), Griffin, T. J. (CoI), Hallstrom, T. C. (CoI), Harki, D. A. (CoI), Hatsukami, D. K. (CoI), Hirsch, B. A. (CoI), Huang, R. S. S. (CoI), Johnson, S. (CoI), Juckett, M. B. (CoI), Lange, C. A. (CoI), Le, C. T. (CoI), Luo, X. (CoI), McKenna, D. H. (CoI), Miller, J. S. (CoI), Moriarity, B. S. (CoI), Muretta, J. M. (CoI), Murray, T. (CoI), Nelson, H. H. (CoI), Ondrey, F. G. (CoI), Patel, M. R. (CoI), Pennell, C. A. (CoI), Petersen, A. J. (CoI), Peterson, L. A. (CoI), Poynter, J. (CoI), Pratt, R. J. (CoI), Sarver, A. L. (CoI), Schendzielos, D. L. (CoI), Schilz, A. (CoI), Schwertfeger, K. (CoI), Seelig, D. (CoI), Shimizu, Y. (CoI), Stepanov, I. (CoI), Temiz, N. A. (CoI), Ventz, S. (CoI), Villalta, P. W. (CoI), Vogel, R. (CoI), Wagner, J. E. (CoI), Wang, J. (CoI), Webber, B. R. (CoI), Weigel, B. J. (CoI), Yamamoto, M. (CoI), Yee, D. (CoI), Zhang, L. (CoI) & Yee, D. (Prior Principal Investigator)
2/1/24 → 1/31/29
Project: Research project
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RET Regulation and Targeting in Neuroendocrine Prostate Cancer
Drake, J. M. (PI), Dehm, S. M. (CoI), Eaton, A. (CoI), Harki, D. A. (CoI) & Hwang, J. (CoI)
5/1/22 → 4/30/27
Project: Research project
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APOBEC Mutagenesis in Breast Cancer
Harki, D. A. (PI), Walters, M. A. (CoI) & Vogel, R. (Other Role)
UT HEALTH SCIENCE CENTER SAN ANTONIO, NATIONAL INSTITUTES OF HEALTH (NIH)
8/1/22 → 7/31/25
Project: Research project
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Development of a Real-Time Fluorescence-Based Deamination Assay and Identification of Inhibitors of Human Cytidine Deaminase
Moorthy, R., Grillo, M. J., Baur, J. W., Schmidt, S. A., Passow, K., Demir, Ö., Tang, J., Olson, M. E., Amaro, R. E. & Harki, D. A., Nov 21 2025, In: ACS Chemical Biology. 20, 11, p. 2593-2600 8 p.Research output: Contribution to journal › Article › peer-review
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Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)
Anderson, J. J. & Harki, D. A., Feb 7 2025, In: RSC Medicinal Chemistry. 16, 4, p. 1681-1685 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders
Tang, J., Moorthy, R., Hirsch, L. E., Demir, Ö., Baker, Z. D., Naumann, J. A., Jones, K. F. M., Grillo, M. J., Haefner, E. S., Shi, K., Levy, M. J., Gupta, H. B., Aihara, H., Harris, R. S., Amaro, R. E., Levinson, N. M. & Harki, D. A., Feb 20 2025, In: Cell Chemical Biology. 32, 2, p. 352-362.e10Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
The Impact of Sugar Conformation on the Single-Stranded DNA Selectivity of APOBEC3A and APOBEC3B Enzymes
Wyllie, M. K., Morris, C. K., Moeller, N. H., Schares, H. A. M., Moorthy, R., Belica, C. A., Grillo, M. J., Demir, Ö., Ayoub, A. M., Carpenter, M. A., Aihara, H., Harris, R. S., Amaro, R. E. & Harki, D. A., Jan 17 2025, In: ACS Chemical Biology. 20, 1, p. 117-127 11 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
A compact stem-loop DNA aptamer targets a uracil-binding pocket in the SARS-CoV-2 nucleocapsid RNA-binding domain
Esler, M. A., Belica, C. A., Rollie, J. A., Brown, W. L., Moghadasi, S. A., Shi, K., Harki, D. A., Harris, R. S. & Aihara, H., Nov 27 2024, In: Nucleic acids research. 52, 21, p. 13138-13151 14 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations