Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 6 Clean Water and Sanitation
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SDG 7 Affordable and Clean Energy
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Collaborations and top research areas from the last five years
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Allosteric mechanisms driving paradoxical activation of RAF kinases
Harki, D. A. (PI) & Levinson, N. M. (PI)
7/1/26 → 6/30/29
Project: Research project
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PROJECT 2 ? CHEMICAL MODULATION OF DNA DEAMINASES IN CANCER
Harki, D. A. (PI)
UT HEALTH SCIENCE CENTER SAN ANTONIO, NATIONAL INSTITUTES OF HEALTH (NIH)
9/19/25 → 8/31/30
Project: Research project
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Novel Protein Degraders for Treating RET Positive Cancer
Drake, J. M. (PI), Harki, D. A. (CoI), Kabir, F. (Graduate Student) & Tengse, S. B. (Graduate Student)
11/1/24 → 10/31/26
Project: Research project
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Cancer Center Support Grant
Miller, J. S. (PI), Antonarakis, E. (CoI), Bachanova, V. (CoI), Balbo, S. (CoI), Beckman, K. B. (CoI), Betts, B. (CoI), Blaes, A. H. (CoI), Cao, Q. (CoI), Eaton, A. (CoI), Ellis, K. M. (CoI), Felices, M. (CoI), Geller, M. A. (CoI), Ghebre, R. G. (CoI), Griffin, T. J. (CoI), Hallstrom, T. C. (CoI), Harki, D. A. (CoI), Hatsukami, D. K. (CoI), Hirsch, B. A. (CoI), Huang, R. S. S. (CoI), Jagtap, P. D. (CoI), Johnson, S. (CoI), Juckett, M. B. (CoI), Lange, C. A. (CoI), Largaespada, D. A. (CoI), Le, C. T. (CoI), Luo, X. (CoI), McKenna, D. H. (CoI), Moriarity, B. S. (CoI), Muretta, J. M. (CoI), Murray, T. (CoI), Nelson, H. H. (CoI), Ondrey, F. G. (CoI), Parsons, H. M. (CoI), Patel, M. R. (CoI), Pennell, C. A. (CoI), Petersen, A. J. (CoI), Peterson, L. A. (CoI), Poynter, J. (CoI), Pratt, R. J. (CoI), Rao, J. S. (CoI), Sarver, A. L. (CoI), Schendzielos, D. L. (CoI), Schilz, A. (CoI), Schwertfeger, K. (CoI), Seelig, D. (CoI), Sherwood, N. E. (CoI), Shimizu, Y. (CoI), Stepanov, I. (CoI), Temiz, N. A. (CoI), Ventz, S. (CoI), Villalta, P. W. (CoI), Vogel, R. (CoI), Wagner, J. E. (CoI), Wang, J. (CoI), Webber, B. R. (CoI), Weigel, B. J. (CoI), Wu, I. H. (CoI), Yamamoto, M. (CoI), Yee, D. (CoI), You, Y. (CoI), Zhang, L. (CoI), DeMist, M. (Other Role), Eschenbacher, H. (Other Role), Johnson, M. L. (Other Role), Khariwala, S. S. (Other Role), Kolaseri Krishnadas, D. (Other Role), Laska, M. N. (Other Role), Moe, S. G. (Other Role), Orcholski, E. (Other Role), Schroeder, M. T. (Other Role) & Sieger, G. K. (Other Role)
2/1/24 → 1/31/29
Project: Research project
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RET Regulation and Targeting in Neuroendocrine Prostate Cancer
Dehm, S. M. (PI), Drake, J. M. (PI), Eaton, A. (PI), Harki, D. A. (PI) & Hwang, J. (CoI)
5/1/22 → 4/30/27
Project: Research project
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A Novel Fluorescence Polarization Binding Assay for the Main Protease (Mpro) of SARS-CoV-2
Wyllie, M. K., Biswas, R. G., Vishwakarma, J., Esler, M. A., Rollie, J. A., Aihara, H., Harris, R. S. & Harki, D. A., Nov 14 2025, In: ACS Pharmacology and Translational Science. 8, 11, p. 4055-4069 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Development of a Real-Time Fluorescence-Based Deamination Assay and Identification of Inhibitors of Human Cytidine Deaminase
Moorthy, R., Grillo, M. J., Baur, J. W., Schmidt, S. A., Passow, K. T., Demir, Ö., Tang, J., Olson, M. E., Amaro, R. E. & Harki, D. A., Nov 21 2025, In: ACS Chemical Biology. 20, 11, p. 2593-2600 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)
Anderson, J. J. & Harki, D. A., Feb 7 2025, In: RSC Medicinal Chemistry. 16, 4, p. 1681-1685 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders
Tang, J., Moorthy, R., Hirsch, L. E., Demir, Ö., Baker, Z. D., Naumann, J. A., Jones, K. F. M., Grillo, M. J., Haefner, E. S., Shi, K., Levy, M. J., Gupta, H. B., Aihara, H., Harris, R. S., Amaro, R. E., Levinson, N. M. & Harki, D. A., Feb 20 2025, In: Cell Chemical Biology. 32, 2, p. 352-362.e10Research output: Contribution to journal › Article › peer-review
Open Access26 Link opens in a new tab Scopus citations -
The Impact of Sugar Conformation on the Single-Stranded DNA Selectivity of APOBEC3A and APOBEC3B Enzymes
Wyllie, M. K., Morris, C. K., Moeller, N. H., Schares, H. A. M., Moorthy, R., Belica, C. A., Grillo, M. J., Demir, Ö., Ayoub, A. M., Carpenter, M. A., Aihara, H., Harris, R. S., Amaro, R. E. & Harki, D. A., Jan 17 2025, In: ACS Chemical Biology. 20, 1, p. 117-127 11 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations