20002020
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects 2011 2020

APOBEC3 STRUCTURAL STUDIES

Harris, R., Aihara, H., Harki, D. A., Nazarian, S. & Shi, K.

NIH NIGMS NATL INST OF GENERAL

4/15/162/29/20

Project: Research project

Assays
Fluorescence
Polarization
Ligands
DNA
Androgen Receptors
Androgens
EPI 001

Research Output 2000 2018

4-Cyanoindole-2′-deoxyribonucleoside (4CIN): A Universal Fluorescent Nucleoside Analogue

Passow, K. T. & Harki, D. A., Jul 20 2018, In : Organic Letters. 20, 14, p. 4310-4313 4 p.

Research output: Contribution to journalArticle

Deoxyribonucleosides
nucleosides
Nucleosides
analogs
Fluorophores
4 Citations

APOBEC Enzymes as Targets for Virus and Cancer Therapy

Olson, M. E., Harris, R. S. & Harki, D. A., Jan 18 2018, In : Cell Chemical Biology. 25, 1, p. 36-49 14 p.

Research output: Contribution to journalReview article

Viruses
Mutagenesis
Uracil
Genes
Cytosine

Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles

Widen, J. C., Kempema, A. M., Baur, J. W., Skopec, H. M., Edwards, J. T., Brown, T. J., Brown, D. A., Meece, F. A. & Harki, D. A., Feb 20 2018, In : ChemMedChem. 13, 4, p. 303-311 9 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Transcription Factor RelA
Bioactivity
Biological Products
Libraries

SN-38 Conjugated Gold Nanoparticles Activated by Ewing Sarcoma Specific mRNAs Exhibit in Vitro and in Vivo Efficacy

Naumann, J. A., Widen, J. C., Jonart, L. A., Ebadi, M., Tang, J., Gordon, D. J., Harki, D. A. & Gordon, P. M., Apr 18 2018, In : Bioconjugate Chemistry. 29, 4, p. 1111-1118 8 p.

Research output: Contribution to journalArticle

irinotecan
Slip forming
Ewing's Sarcoma
Gold
Nanoparticles
25 Citations

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

Jackson, P. A., Widen, J. C., Harki, D. A. & Brummond, K. M., Feb 9 2017, In : Journal of Medicinal Chemistry. 60, 3, p. 839-885 47 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Biological Products
Acrylamide
Drug Discovery
Pharmaceutical Preparations