20002020
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects 2011 2020

APOBEC3 STRUCTURAL STUDIES

Harris, R., Aihara, H., Harki, D. A., Nazarian, S. & Shi, K.

NIH NIGMS NATL INST OF GENERAL

4/15/162/29/20

Project: Research project

Assays
Fluorescence
Polarization
Ligands
DNA
Androgen Receptors
EPI 001

Research Output 2000 2018

4-Cyanoindole-2′-deoxyribonucleoside (4CIN): A Universal Fluorescent Nucleoside Analogue

Passow, K. T. & Harki, D. A., Jul 20 2018, In : Organic Letters. 20, 14, p. 4310-4313 4 p.

Research output: Contribution to journalArticle

Deoxyribonucleosides
nucleosides
Nucleosides
analogs
Fluorophores
6 Citations

APOBEC Enzymes as Targets for Virus and Cancer Therapy

Olson, M. E., Harris, R. & Harki, D. A., Jan 18 2018, In : Cell Chemical Biology. 25, 1, p. 36-49 14 p.

Research output: Contribution to journalReview article

Viruses
Mutagenesis
Uracil
Genes
Cytosine

Determinants of Oligonucleotide Selectivity of APOBEC3B

Wagner, J. R., Demir, Ö., Carpenter, M. A., Aihara, H., Harki, D. A., Harris, R. & Amaro, R. E., Jan 1 2018, (Accepted/In press) In : Journal of Chemical Information and Modeling.

Research output: Contribution to journalArticle

Oligonucleotides
Binding sites
DNA
Binding Sites
determinants

Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles

Widen, J. C., Kempema, A. M., Baur, J. W., Skopec, H. M., Edwards, J. T., Brown, T. J., Brown, D. A., Meece, F. A. & Harki, D. A., Feb 20 2018, In : ChemMedChem. 13, 4, p. 303-311 9 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Transcription Factor RelA
Bioactivity
Biological Products
Libraries

Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor

Divakaran, A., Talluri, S. K., Ayoub, A. M., Mishra, N. K., Cui, H., Widen, J. C., Berndt, N., Zhu, J. Y., Carlson, A. S., Topczewski, J. J., Schonbrunn, E. K., Harki, D. A. & Pomerantz, W. C., Oct 25 2018, In : Journal of Medicinal Chemistry. 61, 20, p. 9316-9334 19 p.

Research output: Contribution to journalArticle

Lysine
Phosphotransferases
Post Translational Protein Processing
Interleukin-8
Epigenomics