1975 …2019

Research output per year

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Research Output

Identification of T cell recognition sites in S-antigen: Dissociation of proliferative and pathogenic sites

Gregerson, D. S., Fling, S. P., Obritsch, W. F., Merryman, C. F. & Donoso, L. A., Oct 15 1989, In : Cellular Immunology. 123, 2, p. 427-440 14 p.

Research output: Contribution to journalArticle

55 Scopus citations
8 Scopus citations

Immune privilege in the retina

Gregerson, D. S., Dec 1 1998, In : Ocular Immunology and Inflammation. 6, 4, p. 257-267 11 p.

Research output: Contribution to journalReview article

25 Scopus citations
20 Scopus citations

Immunoproteasome Deficiency Modifies the Alternative Pathway of NFκB Signaling

Maldonado, M., Kapphahn, R. J., Terluk, M. R., Heuss, N. D., Yuan, C., Gregerson, D. S. & Ferrington, D. A., Feb 14 2013, In : PloS one. 8, 2, e56187.

Research output: Contribution to journalArticle

18 Scopus citations

Immunoproteasome deficiency protects in the retina after optic nerve crush

Schuld, N. J., Hussong, S. A., Kapphahn, R. J., Lehmann, U., Roehrich, H., Rageh, A. A., Heuss, N. D., Bratten, W., Gregerson, D. S. & Ferrington, D. A., May 15 2015, In : PloS one. 10, 5, e0126768.

Research output: Contribution to journalArticle

10 Scopus citations

Immunoproteasome responds to injury in the retina and brain

Ferrington, D. A., Hussong, S. A., Roehrich, H., Kapphahn, B., Kavanaugh, S. M., Heuss, N. D. & Gregerson, D. S., Jul 1 2008, In : Journal of Neurochemistry. 106, 1, p. 158-169 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Immunoproteasomes: Structure, function, and antigen presentation

Ferrington, D. A. & Gregerson, D. S., 2012, Progress in Molecular Biology and Translational Science. Elsevier B.V., p. 75-112 38 p. (Progress in Molecular Biology and Translational Science; vol. 109).

Research output: Chapter in Book/Report/Conference proceedingChapter

156 Scopus citations

Induction of Immunotolerance in rats by intratesticular administration of an eicosapeptide of bovine S-Antigen

Ren, J., Singh, A. K., Gregerson, D. S. & Shichi, H., Jan 1 1996, In : Autoimmunity. 25, 1, p. 19-31 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibition of experimental autoimmune uveitis by retinal photoreceptor antigens coupled to spleen cells

Dua, H. S., Gregerson, D. S. & Donoso, L. A., Feb 1992, In : Cellular Immunology. 139, 2, p. 292-305 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

Inhibition of experimental autoimmune uveoretinitis by oral administration of s-antigen and synthetic peptides

Vrabec, T. R., Gregerson, D. S., Dua, H. S. & Donoso, L. A., Jan 1 1992, In : Autoimmunity. 12, 3, p. 175-184 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Inhibition of in vitro T cell activation by corneal endothelial cells

Obritsch, W. F., Kawashima, H., Evangelista, A., Ketcham, J. M., Holland, E. J. & Gregerson, D. S., Oct 1 1992, In : Cellular Immunology. 144, 1, p. 80-94 15 p.

Research output: Contribution to journalArticle

15 Scopus citations
27 Scopus citations

In vitro unresponsiveness to autologous sequences of the immunopathogenic autoantigen, S-antigen

Fling, S. P., Donoso, L. A. & Gregerson, D. S., Jan 1 1991, In : Journal of Immunology. 147, 2, p. 483-489 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina

Heuss, N. D., Lehmann, U., Norbury, C. C., McPherson, S. W. & Gregerson, D. S., Feb 1 2012, In : Journal of Immunology. 188, 3, p. 1191-1200 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Local "on-demand" generation and function of antigen-specific Foxp3+ regulatory T cells

Mc Pherson, S. W., Heuss, N. D. & Gregerson, D. S., May 15 2013, In : Journal of Immunology. 190, 10, p. 4971-4981 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Local regulation of immune responses: Corneal endothelial cells alter T cell activation and cytokine production

Mi, P., Gregerson, D. S. & Kawashima, H., Mar 2000, In : Cytokine. 12, 3, p. 253-264 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Longitudinal study of serum antibody responses to bovine retinal S-antigen in endogenous granulomatous uveitis

Abrahams, I. W. & Gregerson, D. S., Jan 1 1983, In : British Journal of Ophthalmology. 67, 10, p. 681-684 4 p.

Research output: Contribution to journalArticle

19 Scopus citations

Longitudinal study of serum antibody responses to retinal antigens in acute ocular toxoplasmosis

Abrahams, I. W. & Gregerson, D. S., Feb 1982, In : American journal of ophthalmology. 93, 2, p. 224-231 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
15 Scopus citations

Mechanisms of corneal endothelial cell inhibition of il-2 production

Mi, P., Kawashima, H. & Gregerson, D. S., Dec 1 1996, In : FASEB Journal. 10, 6

Research output: Contribution to journalArticle

Modulation of experimental allergic uveitis by pertussin toxin

Marak, G. E., Gregerson, D. S., Attla, L. & Rao, N. A., Jan 1 1990, Ocular immunology today: proceedings of the 5th International Symposium on the Immunology and Immunopathology of the Eye. ICS918. Usui, M., Ohno, S., Aoki, K., Usui, M., Ohno, S. & Aoki, K. (eds.). Elsevier Science Publishers B.V., p. 435-437 3 p. (Ocular immunology today: proceedings of the 5th International Symposium on the Immunology and Immunopathology of the Eye. ICS918).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Multiple, autoreactive TCR Vβ genes utilized in response to a small pathogenic peptide of an autoantigen in EAU

Fling, S. P., Gold, D. P. & Gregerson, D. S., Jul 1992, In : Cellular Immunology. 142, 2, p. 275-286 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Multiple, spatially distinct t cell epitopes within a pathogenic 123 residue cyanogen bromide peptide of bovine retinal s-antigen

Fling, S. P., Gregerson, D. S., Obritsch, W. F., Boyce-Jacino, M., Merryman, C. F. & Donoso, L. A., Jan 1 1990, In : Current Eye Research. 9, S1, p. 111-117 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mycoplasma arthritidis-induced ocular inflammatory disease

Thirkill, C. E. & Gregerson, D. S., Jan 1 1982, In : Infection and immunity. 36, 2, p. 775-781 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Optic nerve as a source of activated retinal microglia post-injury

Heuss, N. D., Pierson, M. J., Roehrich, H., Mc Pherson, S. W., Gram, A. L., Li, L. & Gregerson, D. S., Jul 23 2018, In : Acta Neuropathologica Communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
1 Scopus citations

Oral tolerance in experimental autoimmune uveoretinitis: Distinct mechanisms of resistance are induced by low dose vs high dose feeding protocols

Gregerson, D. S., Obritsch, W. F. & Donoso, L. A., Jan 1 1993, In : Journal of Immunology. 151, 10, p. 5751-5761 11 p.

Research output: Contribution to journalArticle

163 Scopus citations
24 Scopus citations

Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea

Fling, S. P. & Gregerson, D. S., May 15 1986, In : Analytical Biochemistry. 155, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

735 Scopus citations

Peripheral expression of ocular antigens in regulation and therapy of ocular autoimmunity

Gregerson, D. S., Aug 1 2002, In : International Reviews of Immunology. 21, 2-3, p. 101-121 21 p.

Research output: Contribution to journalReview article

13 Scopus citations
3 Scopus citations

Peripheral induction of tolerance by retinal antigen expression

Gregerson, D. S., Heuss, N. D., Lehmann, U. & McPherson, S. W., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 814-822 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Pharmacologic modulation of acute uveitis with aminonicotinamide

Marak, G. E., Sery, T. W., Gregerson, D., Donoso, L. A. & Rao, N. A., Jan 1 1990, In : Ophthalmic Research. 22, 2, p. 111-116 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
20 Scopus citations

Preparation of overlapping peptides of bovine retinal s-antigen and their localization by immunoblotting with peptide-specific antibodies

Fling, S. P., Knospe, V. & Gregerson, D. S., Jan 1 1988, In : Current Eye Research. 7, 2, p. 191-199 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Processive Nature of Reverse Transcription by Avian Myeloblastosis Virus Deoxyribonucleic Acid Polymerase

Gregerson, D. S., Albert, J. & Reid, T. W., Feb 1 1980, In : Biochemistry. 19, 2, p. 301-306 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
2 Scopus citations
6 Scopus citations

Regulators of immunological responses in the cornea and the anterior chamber of the eye

Jager, M. J., Gregerson, D. S. & Streilein, J. W., Mar 1995, In : Eye (Basingstoke). 9, 2, p. 241-246 6 p.

Research output: Contribution to journalArticle

18 Scopus citations
15 Scopus citations

Resting CD8 T cells recognize β-galactosidase expressed in the immune-privileged retina and mediate autoimmune disease when activated

Mcpherson, S. W., Yang, J., Chan, C. C., Dou, C. & Gregerson, D. S., Nov 1 2003, In : Immunology. 110, 3, p. 386-396 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
15 Scopus citations

Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice

Heuss, N. D., Pierson, M. J., Montaniel, K. R. C., McPherson, S. W., Lehmann, U., Hussong, S. A., Ferrington, D. A., Low, W. C. & Gregerson, D. S., Aug 13 2014, In : Journal of Neuroinflammation. 11, 1, 143.

Research output: Contribution to journalArticle

12 Scopus citations

Retinal expression of a neo-self antigen, β-galactosidase, is not tolerogenic and creates a target for autoimmune uveoretinitis

Gregerson, D. S., Torseth, J. W., Mc Pherson, S. W., Roberts, J. P., Shinohara, T. & Zack, D. J., Jul 15 1999, In : Journal of Immunology. 163, 2, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants

Yamagami, S., Kawashima, H., Tsuru, T., Yamagami, H., Kayagaki, N., Yagita, H., Okumura, K. & Gregerson, D. S., Oct 27 1997, In : Transplantation. 64, 8, p. 1107-1111 5 p.

Research output: Contribution to journalArticle

121 Scopus citations
13 Scopus citations

S-antigen: Preparation and characterization of site-specific monoclonal antibodies

Donoso, L. A., Gregerson, D. S., Smith, L., Robertson, S., Knospe, V., Vrabec, T. & Kalsow, C. M., Jan 1 1990, In : Current Eye Research. 9, 4, p. 343-355 13 p.

Research output: Contribution to journalArticle

50 Scopus citations

S-antigen-specific rat T cell lines recognize peptide fragments of S-antigen and mediate experimental autoimmune uveoretinitis and pinealitis

Gregerson, D. S., Obritsch, W. F., Fling, S. P. & Cameron, J. D., Jan 1 1986, In : Journal of Immunology. 136, 8, p. 2875-2882 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Secretion of a growth promoting activity for Nakano mouse lens epithelial cells by a human retinoblastoma cell line

Tarsio, J. F., Gregerson, D. S., Russell, P. & Reid, T. W., Jan 1 1980, In : Investigative Ophthalmology and Visual Science. 19, Suppl. 4, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations