1975 …2019

Research output per year

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Research Output

2019

The retinal environment induces microglia-like properties in recruited myeloid cells

McPherson, S. W., Heuss, N. D., Lehmann, U., Roehrich, H., Abedin, M. & Gregerson, D. S., Jul 20 2019, In : Journal of Neuroinflammation. 16, 1, 151.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Optic nerve as a source of activated retinal microglia post-injury

Heuss, N. D., Pierson, M. J., Roehrich, H., Mc Pherson, S. W., Gram, A. L., Li, L. & Gregerson, D. S., Jul 23 2018, In : Acta Neuropathologica Communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2017
Open Access
6 Scopus citations
2015

Immunoproteasome deficiency protects in the retina after optic nerve crush

Schuld, N. J., Hussong, S. A., Kapphahn, R. J., Lehmann, U., Roehrich, H., Rageh, A. A., Heuss, N. D., Bratten, W., Gregerson, D. S. & Ferrington, D. A., May 15 2015, In : PloS one. 10, 5, e0126768.

Research output: Contribution to journalArticle

10 Scopus citations
2014
15 Scopus citations

Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice

Heuss, N. D., Pierson, M. J., Montaniel, K. R. C., McPherson, S. W., Lehmann, U., Hussong, S. A., Ferrington, D. A., Low, W. C. & Gregerson, D. S., Aug 13 2014, In : Journal of Neuroinflammation. 11, 1, 143.

Research output: Contribution to journalArticle

13 Scopus citations
2013

Corneal Wound Healing Is Compromised by Immunoproteasome Deficiency

Ferrington, D. A., Roehrich, H., Chang, A. A., Huang, C. W., Maldonado, M., Bratten, W., Rageh, A. A., Heuss, N. D., Gregerson, D. S., Nelson, E. F. & Yuan, C., Jan 30 2013, In : PloS one. 8, 1, e54347.

Research output: Contribution to journalArticle

9 Scopus citations

Immunoproteasome Deficiency Modifies the Alternative Pathway of NFκB Signaling

Maldonado, M., Kapphahn, R. J., Terluk, M. R., Heuss, N. D., Yuan, C., Gregerson, D. S. & Ferrington, D. A., Feb 14 2013, In : PloS one. 8, 2, e56187.

Research output: Contribution to journalArticle

18 Scopus citations

Local "on-demand" generation and function of antigen-specific Foxp3+ regulatory T cells

Mc Pherson, S. W., Heuss, N. D. & Gregerson, D. S., May 15 2013, In : Journal of Immunology. 190, 10, p. 4971-4981 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Immunoproteasomes: Structure, function, and antigen presentation

Ferrington, D. A. & Gregerson, D. S., 2012, Progress in Molecular Biology and Translational Science. Elsevier B.V., p. 75-112 38 p. (Progress in Molecular Biology and Translational Science; vol. 109).

Research output: Chapter in Book/Report/Conference proceedingChapter

160 Scopus citations

Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina

Heuss, N. D., Lehmann, U., Norbury, C. C., McPherson, S. W. & Gregerson, D. S., Feb 1 2012, In : Journal of Immunology. 188, 3, p. 1191-1200 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
6 Scopus citations
2011

Generation of regulatory t cells to antigen expressed in the retina

Mc Pherson, S. W., Heuss, N. D., Lehmann, U. & Gregerson, D. S., Aug 1 2011, In : Current Immunology Reviews. 7, 3, p. 344-349 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
2010

Dendritic cells are early responders to retinal injury

Lehmann, U., Heuss, N. D., Mc Pherson, S. W., Roehrich, H. & Gregerson, D. S., Oct 1 2010, In : Neurobiology of Disease. 40, 1, p. 177-184 8 p.

Research output: Contribution to journalArticle

42 Scopus citations
2009
15 Scopus citations

Peripheral induction of tolerance by retinal antigen expression

Gregerson, D. S., Heuss, N. D., Lehmann, U. & McPherson, S. W., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 814-822 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Viral sequestration of antigen subverts cross presentation to CD8 + T cells

Tewalt, E. F., Grant, J. M., Granger, E. L., Palmer, D. C., Heuss, N. D., Gregerson, D. S., Restifo, N. P. & Norbury, C. C., May 2009, In : PLoS pathogens. 5, 5, e1000457.

Research output: Contribution to journalArticle

25 Scopus citations
2008

Evidence for extrathymic generation of regulatory T cells specific for a retinal antigen

Gregerson, D. S., Heuss, N. D., Lehmann, U. & Mc Pherson, S. W., Apr 1 2008, In : Ophthalmic Research. 40, 3-4, p. 154-159 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Immunoproteasome responds to injury in the retina and brain

Ferrington, D. A., Hussong, S. A., Roehrich, H., Kapphahn, B., Kavanaugh, S. M., Heuss, N. D. & Gregerson, D. S., Jul 1 2008, In : Journal of Neurochemistry. 106, 1, p. 158-169 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Use of a β-galactosidase reporter coupled to cell-specific promoters to examine differentiation of neural progenitor cells in vivo and in vitro

Gregerson, D. S., Jan 1 2008, Stem Cells and Regenerative Medicine. World Scientific Publishing Co., p. 265-289 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2007
27 Scopus citations
2006

Bystander killing of neurons by cytotoxic T cells specific for a glial antigen

Mc Pherson, S. W., Heuss, N. D., Roehrich, H. & Gregerson, D. S., Apr 1 2006, In : Glia. 53, 5, p. 457-466 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Different death stimuli evoke apoptosis via multiple pathways in retinal pigment epithelial cells

Ferrington, D. A., Tran, T. N., Lew, K. L., Van Remmen, H. & Gregerson, D. S., Sep 1 2006, In : Experimental Eye Research. 83, 3, p. 638-650 13 p.

Research output: Contribution to journalArticle

31 Scopus citations
13 Scopus citations

Identification of EGFRvIII-derived CTL epitopes estricted by HLA A0201 for dendritic cell based immunotherapy of gliomas

Wu, A. H., Xiao, J., Anker, L., Hall, W. A., Gregerson, D. S., Cavenee, W. K., Chen, W. & Low, W. C., Jan 1 2006, In : Journal of neuro-oncology. 76, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

42 Scopus citations
13 Scopus citations
2005
3 Scopus citations
2004

APC derived from donor splenocytes support retinal autoimmune disease in allogeneic recipients

Gregerson, D. S. & Kawashima, H., Aug 1 2004, In : Journal of Leukocyte Biology. 76, 2, p. 383-387 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

The antigen-presenting activity of fresh, adult parenchymal microglia and perivascular cells from retina

Gregerson, D. S., Sam, T. N. & McPherson, S. W., Jun 1 2004, In : Journal of Immunology. 172, 11, p. 6587-6597 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
2003
40 Scopus citations

Effects of Total Body Irradiation and Cyclosporin A on the Lethality of Toxic Shock Syndrome Toxin-1 in a Rabbit Model of Toxic Shock Syndrome

Dinges, M. M., Gregerson, D. S., Tripp, T. J., McCormick, J. K. & Schlievert, P. M., Oct 15 2003, In : Journal of Infectious Diseases. 188, 8, p. 1142-1145 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Resting CD8 T cells recognize β-galactosidase expressed in the immune-privileged retina and mediate autoimmune disease when activated

Mcpherson, S. W., Yang, J., Chan, C. C., Dou, C. & Gregerson, D. S., Nov 1 2003, In : Immunology. 110, 3, p. 386-396 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
2002

Peripheral expression of ocular antigens in regulation and therapy of ocular autoimmunity

Gregerson, D. S., Aug 1 2002, In : International Reviews of Immunology. 21, 2-3, p. 101-121 21 p.

Research output: Contribution to journalReview article

13 Scopus citations

Spontaneous induction of immunoregulation by an endogenous retinal antigen

Gregerson, D. S. & Dou, C., Sep 1 2002, In : Investigative Ophthalmology and Visual Science. 43, 9, p. 2984-2991 8 p.

Research output: Contribution to journalArticle

33 Scopus citations
2001

Failure of memory (CD44 high) CD4 T cells to recognize their target antigen in retina

Gregerson, D. S. & Xiao, J., Nov 10 2001, In : Journal of Neuroimmunology. 120, 1-2, p. 34-41 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2000

Local regulation of immune responses: Corneal endothelial cells alter T cell activation and cytokine production

Mi, P., Gregerson, D. S. & Kawashima, H., Mar 2000, In : Cytokine. 12, 3, p. 253-264 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
1999

Effects of continuous localized infusion of granulocyte-macrophage colony-stimulating factor and inoculations of irradiated glioma cells on tumor regression

Wallenfriedman, M. A., Conrad, J. A., DelaBarre, L., Graupman, P. C., Lee, G., Garwood, M., Gregerson, D. S., Jean, W. C., Hall, W. A. & Low, W. C., Jun 1999, In : Journal of neurosurgery. 90, 6, p. 1064-1071 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Ex vivo transduction of corneal epithelial progenitor cells using a retroviral vector

Bradshaw, J. J., Obritsch, W. F., Cho, B. J., Gregerson, D. S. & Holland, E. J., Jan 20 1999, In : Investigative Ophthalmology and Visual Science. 40, 1, p. 230-235 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Retinal expression of a neo-self antigen, β-galactosidase, is not tolerogenic and creates a target for autoimmune uveoretinitis

Gregerson, D. S., Torseth, J. W., Mc Pherson, S. W., Roberts, J. P., Shinohara, T. & Zack, D. J., Jul 15 1999, In : Journal of Immunology. 163, 2, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Systemic expression of rat soluble retinal antigen induces resistance to experimental autoimmune uveoretinitis

Mc Pherson, S. W., Roberts, J. P. & Gregerson, D. S., Oct 20 1999, In : Journal of Immunology. 163, 8, p. 4269-4276 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
1998

A new model of proliferative vitreoretinopathy

Frenzel, E. M., Neely, K. A., Walsh, A. W., Cameron, J. D. & Gregerson, D. S., Oct 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 11, p. 2157-2164 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Immune privilege in the retina

Gregerson, D. S., Dec 1 1998, In : Ocular Immunology and Inflammation. 6, 4, p. 257-267 11 p.

Research output: Contribution to journalReview article

25 Scopus citations
24 Scopus citations
1997

A new, simple, nonradioactive, nontoxic in vitro assay to monitor corneal endothelial cell viability

Larson, E. M., Doughman, D. J., Gregerson, D. S. & Obritsch, W. F., Sep 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 10, p. 1929-1933 5 p.

Research output: Contribution to journalArticle

101 Scopus citations
24 Scopus citations

Antigen presentation in uveitis

Prasad, S. A. & Gregerson, D. S., Jan 1 1997, In : Eye. 11, 2, p. 176-182 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Differential APC requirements of self- and nonself-reactive T cells and T cell hybridomas specific for retinal S-antigen

Prasad, S. A., Fling, S. P. & Gregerson, D. S., Feb 1997, In : Journal of Autoimmunity. 10, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of FAS/FAS-LIG and interaction on the induction of acaid

Kawashima, H., Yamagami, S. & Gregerson, D. S., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4, p. S183

Research output: Contribution to journalArticle

1 Scopus citations

Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants

Yamagami, S., Kawashima, H., Tsuru, T., Yamagami, H., Kayagaki, N., Yagita, H., Okumura, K. & Gregerson, D. S., Oct 27 1997, In : Transplantation. 64, 8, p. 1107-1111 5 p.

Research output: Contribution to journalArticle

122 Scopus citations