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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Research Output 1989 2019

In vivo activity and low toxicity of the second-generation antimicrobial peptide DGL13K

Gorr, S. U., Flory, C. M. & Schumacher, R. J., May 1 2019, In : PloS one. 14, 5, e0216669.

Research output: Contribution to journalArticle

Open Access
antimicrobial peptides
Galleria mellonella
Toxicity
peptides
toxicity
1 Citation (Scopus)

Novel N-1 substituted fluoroquinolones inhibit human topoisomerase I activity and exhibit anti-proliferative activity

Oppegard, L. M., Delgado, J. L., Kulkarni, C. A., Towle, T. R., Hart, D. E., Williams, B. P., Lentz, S. R. C., Norris, B., Flory, C. M., Schumacher, R. J., Murry, D. J., Kerns, R. J. & Hiasa, H., Apr 15 2019, In : Investigational New Drugs. 37, 2, p. 378-383 6 p.

Research output: Contribution to journalArticle

Type I DNA Topoisomerase
Fluoroquinolones
Heterografts
Human Activities
Poisoning
3 Citations (Scopus)

Erratum: Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria (Cell Chemical Biology (2017) 24(10) (1259–1275.e6) (S2451945617302830)(10.1016/j.chembiol.2017.08.009))

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, 1 p.

Research output: Contribution to journalComment/debate

Biguanides
Mitochondria
Heme
Cytochrome P-450 Enzyme System
Cell Biology
3 Citations (Scopus)

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, p. 1259-1275.e6

Research output: Contribution to journalArticle

Open Access
Biguanides
Cytochrome P-450 CYP3A
Mitochondria
Heme
Cytochrome P-450 Enzyme System
49 Citations (Scopus)

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis

Jüngel, A., Ospelt, C., Lesch, M., Thiel, M., Sunyer, T., Schorr, O., Michel, B. A., Gay, R. E., Kolling, C., Flory, C., Gay, S. & Neidhart, M., May 1 2010, In : Annals of the Rheumatic Diseases. 69, 5, p. 898-902 5 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 13
Matrix Metalloproteinase Inhibitors
Cartilage
Rheumatoid Arthritis
Animals