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Courtney Aldrich

20002023
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 6 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Biosynthesis Chemical Compounds
Siderophores Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Peptide Synthases Medicine & Life Sciences
Polyketide Synthases Chemical Compounds
Assays Chemical Compounds
Biotin Medicine & Life Sciences

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Projects 2006 2023

Target based discovery of next generation pyrazinamide

Aldrich, C.

HACKENSACK MERIDIAN HEALTH, INC

6/1/19 → 5/31/20

Project: Research project

Targeting Biotin Metabolism in Mycobacterium Tuberculosis

Aldrich, C. & Ferguson, D. M.

NIH Nat'l Inst of Allergy & Infect Dis

1/15/19 → 12/31/23

Project: Research project

Biotin
Mycobacterium tuberculosis

The Structural Basis for Nonribosomal Peptide Biosynthesis

Aldrich, C.

THE STATE UNIVERSITY OF NEW YORK BUFFALO

7/1/18 → 12/31/19

Project: Research project

Biosynthesis
Peptides

Siderophore Inhibitors for Tuberculosis that Block Mycob

Aldrich, C. & Ferguson, D. M.

NIH Nat'l Inst of Allergy & Infect Dis

4/25/18 → 3/31/23

Project: Research project

Siderophores
Tuberculosis
mycobactins

High-Throughput Screens to Discover Novel Inhibitors of

Cornea, R. L., Aldrich, C. & Thomas, D. D.

NIH Nat'l Heart, Lung, and Blood Inst.

1/15/18 → 11/30/21

Project: Research project

Ryanodine Receptor Calcium Release Channel
Heart Failure
Therapeutics

Research Output 2000 2019

1 Citation (Scopus)

A Cinchona Alkaloid Antibiotic That Appears to Target ATP Synthase in Streptococcus pneumoniae

Wang, X., Zeng, Y., Sheng, L., Larson, P., Liu, X., Zou, X., Wang, S., Guo, K., Ma, C., Zhang, G., Cui, H., Ferguson, D. M., Li, Y., Zhang, J. & Aldrich, C., Mar 14 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2305-2332 28 p.

Research output: Contribution to journal › Article

Cinchona Alkaloids
Quinuclidines
Streptococcus pneumoniae
Adenosine Triphosphate
Anti-Bacterial Agents

Development of an imidazole salt catalytic system for the preparation of bis(indolyl) methanes and bis(naphthyl)methane

Wang, X. & Aldrich, C., Apr 1 2019, In : PloS one. 14, 4, e0216008.

Research output: Contribution to journal › Article

Open Access
naphthols
Naphthols
imidazoles
Methane
methane

Investigation of (S)-(-)-acidomycin: A selective antimycobacterial natural product that inhibits biotin synthase

Bockman, M. R., Engelhart, C. A., Cramer, J. D., Howe, M. D., Mishra, N. K., Zimmerman, M., Larson, P., Alvarez-Cabrera, N., Park, S. W., Boshoff, H. I. M., Bean, J. M., Young, V. G., Ferguson, D. M., Dartois, V., Jarrett, J. T., Schnappinger, D. & Aldrich, C., Apr 12 2019, In : ACS Infectious Diseases. 5, 4, p. 598-617 20 p.

Research output: Contribution to journal › Article

Biological Products
Microbial Sensitivity Tests
Biotin
Tuberculosis
Multidrug-Resistant Tuberculosis

Macozinone: Revised synthesis and crystal structure of a promising new drug for treating drug-sensitive and drug-resistant tuberculosis

Zhang, G. & Aldrich, C., Aug 1 2019, In : Acta Crystallographica Section C: Structural Chemistry. 75, p. 1031-1035 5 p.

Research output: Contribution to journal › Article

tuberculosis
drugs
Crystal structure
Nuclear magnetic resonance
crystal structure

Mechanism of a Standalone β-Lactone Synthetase: New Continuous Assay for a Widespread ANL Superfamily Enzyme

Robinson, S. L., Christenson, J. K., Richman, J. E., Jenkins, D. J., Neres, J., Fonseca, D. R., Aldrich, C. & Wackett, L. P., Jul 1 2019, In : ChemBioChem. 20, 13, p. 1701-1711 11 p.

Research output: Contribution to journal › Article

Lactones
Ligases
Assays
Enzymes
Xanthomonas campestris