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Courtney Aldrich

20002023
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 4 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Biosynthesis Chemical Compounds
Siderophores Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Peptide Synthases Medicine & Life Sciences
Polyketide Synthases Chemical Compounds
Assays Chemical Compounds
Biotin Medicine & Life Sciences

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Projects 2006 2023

Targeting Biotin Metabolism in Mycobacterium Tuberculosis

Aldrich, C. & Ferguson, D. M.

NIH Nat'l Inst of Allergy & Infect Dis

1/15/19 → 12/31/23

Project: Research project

Biotin
Mycobacterium tuberculosis

The Structural Basis for Nonribosomal Peptide Biosynthesis

Aldrich, C.

THE STATE UNIVERSITY OF NEW YORK BUFFALO

7/1/18 → 12/31/19

Project: Research project

Biosynthesis
Peptides

Siderophore Inhibitors for Tuberculosis that Block Mycob

Aldrich, C. & Ferguson, D. M.

NIH Nat'l Inst of Allergy & Infect Dis

4/25/18 → 3/31/23

Project: Research project

Siderophores
Tuberculosis
mycobactins

High-Throughput Screens to Discover Novel Inhibitors of

Cornea, R. L., Aldrich, C. & Thomas, D. D.

NIH Nat'l Heart, Lung, and Blood Inst.

1/15/18 → 11/30/21

Project: Research project

Ryanodine Receptor Calcium Release Channel
Heart Failure
Therapeutics

Menaquinone Biosynthesis: A Drug Target in Gram-Positive

Aldrich, C.

Colorado State University

9/1/15 → 2/29/20

Project: Research project

Vitamin K 2
Gram-Positive Bacteria
Pharmaceutical Preparations

Research Output 2000 2019

A Cinchona Alkaloid Antibiotic That Appears to Target ATP Synthase in Streptococcus pneumoniae

Wang, X., Zeng, Y., Sheng, L., Larson, P., Liu, X., Zou, X., Wang, S., Guo, K., Ma, C., Zhang, G., Cui, H., Ferguson, D. M., Li, Y., Zhang, J. & Aldrich, C., Mar 14 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2305-2332 28 p.

Research output: Contribution to journal › Article

Cinchona Alkaloids
Quinuclidines
Streptococcus pneumoniae
Adenosine Triphosphate
Anti-Bacterial Agents

Development of an imidazole salt catalytic system for the preparation of bis(indolyl) methanes and bis(naphthyl)methane

Wang, X. & Aldrich, C., Apr 1 2019, In : PloS one. 14, 4, e0216008.

Research output: Contribution to journal › Article

Open Access
naphthols
Naphthols
imidazoles
Methane
methane

Investigation of (S)-(-)-acidomycin: A selective antimycobacterial natural product that inhibits biotin synthase

Bockman, M. R., Engelhart, C. A., Cramer, J. D., Howe, M. D., Mishra, N. K., Zimmerman, M., Larson, P., Alvarez-Cabrera, N., Park, S. W., Boshoff, H. I. M., Bean, J. M., Young, V. G., Ferguson, D. M., Dartois, V., Jarrett, J. T., Schnappinger, D. & Aldrich, C., Apr 12 2019, In : ACS Infectious Diseases. 5, 4, p. 598-617 20 p.

Research output: Contribution to journal › Article

Biological Products
Microbial Sensitivity Tests
Biotin
Tuberculosis
Multidrug-Resistant Tuberculosis

Mechanism of a Standalone β-Lactone Synthetase: New Continuous Assay for a Widespread ANL Superfamily Enzyme

Robinson, S. L., Christenson, J. K., Richman, J. E., Jenkins, D. J., Neres, J., Fonseca, D. R., Aldrich, C. & Wackett, L. P., Jan 1 2019, In : ChemBioChem.

Research output: Contribution to journal › Article

Lactones
Ligases
Assays
Enzymes
Xanthomonas campestris

Spirocyclic and Bicyclic 8-Nitrobenzothiazinones for Tuberculosis with Improved Physicochemical and Pharmacokinetic Properties

Zhang, G., Howe, M. & Aldrich, C., Mar 14 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 348-351 4 p.

Research output: Contribution to journal › Article

Pharmacokinetics
Tuberculosis
Solubility
Antitubercular Agents
Diamines