Conrado Aparicio

PhD

Accepting PhD Students

19982022
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Research Output 1998 2019

2019

Bioinspired Mineralization with Hydroxyapatite and Hierarchical Naturally Aligned Nanofibrillar Cellulose

Qi, Y., Cheng, Z., Ye, Z., Zhu, H. & Aparicio, C., Aug 7 2019, In : ACS Applied Materials and Interfaces. 11, 31, p. 27598-27604 7 p.

Research output: Contribution to journalArticle

Durapatite
Hydroxyapatite
Cellulose
carbopol 940
Hydrogel
Dental Implant-Abutment Design
Finite Element Analysis
Silver Nitrate
Research

Dentin Priming with Amphipathic Antimicrobial Peptides

Moussa, D. G., Kirihara, J. A., Ye, Z., Fischer, N. G., Khot, J., Witthuhn, B. A. & Aparicio, C., Sep 1 2019, In : Journal of dental research. 98, 10, p. 1112-1121 10 p.

Research output: Contribution to journalArticle

Dentin
Peptides
Minerals
Collagen
Multimodal Imaging
1 Citation (Scopus)

Hydrophobic and antimicrobial dentin: A peptide-based 2-tier protective system for dental resin composite restorations

Moussa, D. G., Fok, A. & Aparicio, C., Apr 1 2019, In : Acta Biomaterialia. 88, p. 251-265 15 p.

Research output: Contribution to journalArticle

Dentin
Peptides
Restoration
Resins
Composite Resins
1 Citation (Scopus)

Nano-scale modification of titanium implant surfaces to enhance osseointegration

Souza, J. C. M., Sordi, M. B., Kanazawa, M., Ravindran, S., Henriques, B., Silva, F. S., Aparicio, C. & Cooper, L. F., Aug 1 2019, In : Acta Biomaterialia. 94, p. 112-131 20 p.

Research output: Contribution to journalReview article

Osseointegration
Titanium
Biomimetics
Wettability
Peptides
1 Citation (Scopus)

PLA-based mineral-doped scaffolds seeded with human periapical cyst-derived MSCs: A promising tool for regenerative healing in dentistry

Tatullo, M., Spagnuolo, G., Codispoti, B., Zamparini, F., Zhang, A., Esposti, M. D., Aparicio, C., Rengo, C., Nuzzolese, M., Manzoli, L., Fava, F., Prati, C., Fabbri, P. & Gandolfi, M. G., Feb 16 2019, In : Materials. 12, 4, 597.

Research output: Contribution to journalArticle

Open Access
Dentistry
Scaffolds
Minerals
Stem cells
Acids
4 Citations (Scopus)

Present and future of tissue engineering scaffolds for dentin-pulp complex regeneration

Moussa, D. G. & Aparicio, C., Jan 1 2019, In : Journal of Tissue Engineering and Regenerative Medicine. 13, 1, p. 58-75 18 p.

Research output: Contribution to journalReview article

Tissue Scaffolds
Dentin
Tissue Engineering
Scaffolds (biology)
Tissue engineering

Recombinant AMP/Polypeptide Self-Assembled Monolayers with Synergistic Antimicrobial Properties for Bacterial Strains of Medical Relevance

Acosta, S., Quintanilla, L., Alonso, M., Aparicio, C. & Rodríguez-Cabello, J. C., Sep 9 2019, In : ACS Biomaterials Science and Engineering. 5, 9, p. 4708-4716 9 p.

Research output: Contribution to journalArticle

Polypeptides
Self assembled monolayers
Peptides
Elastin
Biofilms
5 Citations (Scopus)

Self-assembly dynamics and antimicrobial activity of all l- and d-amino acid enantiomers of a designer peptide

Ye, Z., Zhu, X., Acosta, S., Kumar, D., Sang, T. & Aparicio, C., Jan 7 2019, In : Nanoscale. 11, 1, p. 266-275 10 p.

Research output: Contribution to journalArticle

Open Access
Enantiomers
Self assembly
Peptides
Amino acids
Amino Acids
2018
2 Citations (Scopus)

Bacterial microleakage at the abutment-implant interface, in vitro study

Larrucea, C., Aparicio, C., Olivares, D., Padilla, C., Barrera, A. & Lobos, O., Jun 1 2018, In : Clinical Implant Dentistry and Related Research. 20, 3, p. 360-367 8 p.

Research output: Contribution to journalArticle

Torque
Porphyromonas gingivalis
Microbiota
Rehabilitation
Inflammation
2 Citations (Scopus)

Effects of Molecular Weight and Concentration of Poly(Acrylic Acid) on Biomimetic Mineralization of Collagen

Qi, Y., Ye, Z., Fok, A., Holmes, B. N., Espanol, M., Ginebra, M. P. & Aparicio, C., Aug 13 2018, In : ACS Biomaterials Science and Engineering. 4, 8, p. 2755-2766 12 p.

Research output: Contribution to journalArticle

carbopol 940
Biomimetics
Collagen
Acrylics
Molecular weight
1 Citation (Scopus)

In vitro cell response on CP-Ti surfaces functionalized with TGF-β1 inhibitory peptides

Sevilla, P., Cirera, A., Dotor, J., Gil, F. J., Galindo-Moreno, P. & Aparicio, C., Jun 1 2018, In : Journal of Materials Science: Materials in Medicine. 29, 6, 73.

Research output: Contribution to journalArticle

Osseointegration
Differentiation Antigens
Peptides
Titanium
Osteoblasts

Mechanism of fracture of NiTi superelastic endodontic rotary instruments

Gil, J., Rupérez, E., Velasco, E., Aparicio, C. & Manero, J. M., Aug 1 2018, In : Journal of Materials Science: Materials in Medicine. 29, 8, 131.

Research output: Contribution to journalArticle

Endodontics
Enthalpy
Structure Collapse
Calorimetry
Service life

Nanostructured surfaces of cranio-maxillofacial and dental implants

Souza, J. C. M., Bins-Ely, L., Sordi, M. B., Magini, R. S., Aparicio, C., Shokuhfar, T. & Cooper, L., Apr 14 2018, Nanostructured Biomaterials for Cranio-Maxillofacial and Oral Applications. Elsevier Inc., p. 13-40 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dental prostheses
Dental Implants
5 Citations (Scopus)

Peptide coatings enhance keratinocyte attachment towards improving the peri-implant mucosal seal

Koidou, V., Argyris, P., Skoe, E. P., Mota Siqueira, J., Chen, X., Zhang, L., Hinrichs, J. E., Costalonga, M. & Aparicio, C., Jul 1 2018, In : Biomaterials Science. 6, 7, p. 1936-1945 10 p.

Research output: Contribution to journalArticle

Open Access
Peptides
Seals
Coatings
Dental prostheses
Titanium
13 Citations (Scopus)

Polylactic acid-based porous scaffolds doped with calcium silicate and dicalcium phosphate dihydrate designed for biomedical application

Gandolfi, M. G., Zamparini, F., Degli Esposti, M., Chiellini, F., Aparicio, C., Fava, F., Fabbri, P., Taddei, P. & Prati, C., Jan 1 2018, In : Materials Science and Engineering C. 82, p. 163-181 19 p.

Research output: Contribution to journalArticle

calcium silicates
Calcium silicate
Scaffolds
phosphates
Phosphates
2017
6 Citations (Scopus)

Chitosan-recombinamer layer-by-layer coatings for multifunctional implants

Govindharajulu, J. P., Chen, X., Li, Y., Rodriguez-Cabello, J. C., Battacharya, M. & Aparicio, C., Feb 9 2017, In : International Journal of Molecular Sciences. 18, 2, 369.

Research output: Contribution to journalArticle

Open Access
Chitosan
Biomineralization
Titanium
coatings
Coatings
3 Citations (Scopus)

Differential neuronal and glial behavior on flat and micro patterned chitosan films

Mattotti, M., Alvarez, Z., Delgado, L., Mateos-Timoneda, M. A., Aparicio, C., Planell, J. A., Alcántara, S. & Engel, E., Oct 1 2017, In : Colloids and Surfaces B: Biointerfaces. 158, p. 569-577 9 p.

Research output: Contribution to journalArticle

Chitosan
Neuroglia
axons
grooves
central nervous system
1 Citation (Scopus)
Open Access
Biofilms
Adhesives
Tooth
Sucrose
Third Molar
8 Citations (Scopus)

Intrafibrillar Mineralization of Self-Assembled Elastin-Like Recombinamer Fibrils

Li, Y., Rodriguez-Cabello, J. C. & Aparicio, C., Feb 22 2017, In : ACS Applied Materials and Interfaces. 9, 7, p. 5838-5846 9 p.

Research output: Contribution to journalArticle

Elastin
Collagen
Biomineralization
Durapatite
Hydroxyapatite
5 Citations (Scopus)

In vivo osseointegration of dental implants with an antimicrobial peptide coating

Chen, X., Zhou, X. C., Liu, S., Wu, R. F., Aparicio, C. & Wu, J. Y., May 1 2017, In : Journal of Materials Science: Materials in Medicine. 28, 5, 76.

Research output: Contribution to journalArticle

Osseointegration
Dental prostheses
Dental Implants
Peptides
Rabbits
3 Citations (Scopus)

Relevant Properties for Immobilizing Short Peptides on Biosurfaces

Sevilla, P., Gil, J. & Aparicio, C., Oct 1 2017, In : IRBM. 38, 5, p. 256-265 10 p.

Research output: Contribution to journalArticle

Peptides
Adsorption
Oligopeptides
Biocompatible Materials
Biomaterials
7 Citations (Scopus)

Solution and Solid-State Nuclear Magnetic Resonance Structural Investigations of the Antimicrobial Designer Peptide GL13K in Membranes

Harmouche, N., Aisenbrey, C., Porcelli, F., Xia, Y., Nelson, S. E., Chen, X., Raya, J., Vermeer, L., Aparicio, C., Veglia, G., Gorr, S-U. & Bechinger, B., Aug 15 2017, In : Biochemistry. 56, 32, p. 4269-4278 10 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Membranes
Peptides
Conformations
2016
15 Citations (Scopus)

Antimicrobial agents used in the treatment of peri-implantitis alter the physicochemistry and cytocompatibility of titanium surfaces

Kotsakis, G. A., Lan, C., Barbosa, J., Lill, K., Chen, R., Rudney, J. D. & Aparicio, C., Jul 1 2016, In : Journal of periodontology. 87, 7, p. 809-819 11 p.

Research output: Contribution to journalArticle

Peri-Implantitis
Anti-Infective Agents
Titanium
Decontamination
Therapeutics
19 Citations (Scopus)

Bioactive macroporous titanium implants highly interconnected

Caparrós, C., Ortiz-Hernandez, M., Molmeneu, M., Punset, M., Calero, J. A., Aparicio, C., Fernández-Fairén, M., Perez, R. & Gil, F. J., Oct 1 2016, In : Journal of Materials Science: Materials in Medicine. 27, 10, 151.

Research output: Contribution to journalArticle

Titanium
Bone
Apatites
Bone Development
Apatite
7 Citations (Scopus)

Dentin-composite bond strength measurement using the Brazilian disk test

Carrera, C. A., Chen, Y. C., Li, Y., Rudney, J. D., Aparicio, C. & Fok, A., Sep 1 2016, In : Journal of Dentistry. 52, p. 37-44 8 p.

Research output: Contribution to journalArticle

Dentin
Adhesives
Composite Resins
Acoustics
Electron Scanning Microscopy
1 Citation (Scopus)

Development of a 3D matrix for modeling mammalian spinal cord injury in vitro

Quiroz, J. F. D., Li, Y., Aparicio, C. & Echeverri, K., Jan 1 2016, In : Neural Regeneration Research. 11, 11, p. 1810-1815 6 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Cell Communication
Neuroglia
Cicatrix
Spinal Cord Regeneration
6 Citations (Scopus)

Surface immobilization and bioactivity of TGF-β1 inhibitor peptides for bone implant applications

Sevilla, P., Vining, K. V., Dotor, J., Rodriguez, D., Gil, F. J. & Aparicio, C., Feb 1 2016, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 104, 2, p. 385-394 10 p.

Research output: Contribution to journalArticle

Bioactivity
Peptides
Bone
Tissue
Cytokines
2015
17 Citations (Scopus)

Biomimetic Mineralization of Recombinamer-Based Hydrogels toward Controlled Morphologies and High Mineral Density

Li, Y., Chen, X., Fok, A., Rodriguez-Cabello, J. C. & Aparicio, C., Nov 25 2015, In : ACS Applied Materials and Interfaces. 7, 46, p. 25784-25792 9 p.

Research output: Contribution to journalArticle

Elastin
Hydrogels
Biomimetics
Minerals
Durapatite
13 Citations (Scopus)

Biomineralization and Biomaterials: Fundamentals and Applications

Aparicio, C. & Ginebra, M. P., Sep 25 2015, Elsevier Inc. 482 p.

Research output: Book/ReportBook

Biocompatible Materials
Nacre
Organism Forms
Bone and Bones
Biomimetics
4 Citations (Scopus)

Development of tantalum scaffold for orthopedic applications produced by space-holder method

Rupérez, E., Manero, J. M., Riccardi, K., Li, Y., Aparicio, C. & Gil, F. J., Oct 15 2015, In : Materials and Design. 83, p. 112-119 8 p.

Research output: Contribution to journalArticle

Tantalum
Orthopedics
Scaffolds
Elastic moduli
Sodium chloride
4 Citations (Scopus)

Fatigue failure of dentin-composite disks subjected to cyclic diametral compression

Li, Y., Carrera, C., Chen, R., Li, J., Chen, Y-C., Lenton, P. A., Rudney, J. D., Jones, R. S., Aparicio, C. & Fok, A., Jan 1 2015, In : Dental Materials. 31, 7, p. 778-788 11 p.

Research output: Contribution to journalArticle

Dentin
Fatigue
Tooth
Compaction
Fatigue of materials
5 Citations (Scopus)

Peptide-functionalized zirconia and new zirconia/titanium biocermets for dental applications

Fernandez-Garcia, E., Chen, X., Gutierrez-Gonzalez, C. F., Fernandez, A., Lopez-Esteban, S. & Aparicio, C., Sep 1 2015, In : Journal of Dentistry. 43, 9, p. 1162-1174 13 p.

Research output: Contribution to journalArticle

Oligopeptides
Titanium
Tooth
Peptides
Osteoblasts

Preface

Aparicio, C. & Ginebra, M. P., Sep 25 2015, Biomineralization and Biomaterials: Fundamentals and Applications. Elsevier Inc., p. xi-xiv

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

31 Citations (Scopus)

The use of micro-CT with image segmentation to quantify leakage in dental restorations

Carrera, C. A., Lan, C., Escobar Sanabria, D., Li, Y., Rudney, J. D., Aparicio, C. & Fok, A., Apr 1 2015, In : Dental Materials. 31, 4, p. 382-390 9 p.

Research output: Contribution to journalArticle

Dental Leakage
Silver Nitrate
Image segmentation
Restoration
Tomography
2014
23 Citations (Scopus)

A bioactive elastin-like recombinamer reduces unspecific protein adsorption and enhances cell response on titanium surfaces

Salvagni, E., Berguig, G., Engel, E., Rodriguez-Cabello, J. C., Coullerez, G., Textor, M., Planell, J. A., Gil, F. J. & Aparicio, C., Feb 1 2014, In : Colloids and Surfaces B: Biointerfaces. 114, p. 225-233 9 p.

Research output: Contribution to journalArticle

elastin
Elastin
activity (biology)
Titanium
Adsorption
47 Citations (Scopus)
Streptococcus gordonii
antimicrobial peptides
Biofilms
biofilm
coatings
7 Citations (Scopus)
Optical tomography
Aluminum Oxide
Optical properties
Polarization
Infrared radiation
21 Citations (Scopus)

Biomimetic treatment on dental implants for short-term bone regeneration

Gil, F. J., Manzanares, N., Badet, A., Aparicio, C. & Ginebra, M. P., Jan 1 2014, In : Clinical oral investigations. 18, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

Biomimetics
Bone Regeneration
Dental Implants
Miniature Swine
Osseointegration
37 Citations (Scopus)

Collagen-functionalised titanium surfaces for biological sealing of dental implants: Effect of immobilisation process on fibroblasts response

Marín-Pareja, N., Salvagni, E., Guillem-Marti, J., Aparicio, C. & Ginebra, M. P., Oct 1 2014, In : Colloids and Surfaces B: Biointerfaces. 122, p. 601-610 10 p.

Research output: Contribution to journalArticle

Dental prostheses
Dental Implants
sealing
fibroblasts
Fibroblasts
34 Citations (Scopus)

Degradation in the dentin-composite interface subjected to multi-species biofilm challenges

Li, Y., Carrera, C., Chen, R., Li, J., Lenton, P. A., Rudney, J. D., Jones, R. S., Aparicio, C. & Fok, A., Jan 1 2014, In : Acta Biomaterialia. 10, 1, p. 375-383 9 p.

Research output: Contribution to journalArticle

Biofilms
Dentin
Degradation
Composite materials
Sugar (sucrose)
17 Citations (Scopus)

Hybrid Nanotopographical Surfaces Obtained by Biomimetic Mineralization of Statherin-Inspired Elastin-Like Recombinamers

Li, Y., Chen, X., Ribeiro, A. J., Jensen, E. D., Holmberg, K. V., Rodriguez-Cabello, J. C. & Aparicio, C., Oct 1 2014, In : Advanced Healthcare Materials. 3, 10, p. 1638-1647 10 p.

Research output: Contribution to journalArticle

Elastin
Biomimetics
Minerals
Dental Implants
Orthopedics
2013
25 Citations (Scopus)

Antimicrobial properties and dentin bonding strength of magnesium phosphate cements

Mestres, G., Abdolhosseini, M., Bowles, W. R., Huang, S. H., Aparicio, C., Gorr, S-U. & Ginebra, M. P., Sep 1 2013, In : Acta Biomaterialia. 9, 9, p. 8384-8393 10 p.

Research output: Contribution to journalArticle

Dentin
Magnesium
Cements
Phosphates
Pulp Capping and Pulpectomy Agents
12 Citations (Scopus)

Bioactive Ceramic and Metallic Surfaces for Bone Engineering

Mas-Moruno, C., Espanol, M., Montufar, E. B., Mestres, G., Aparicio, C., Gil, F. J. & Ginebra, M. P., Jul 24 2013, Biomaterials Surface Science. Wiley-VCH Verlag, p. 337-374 38 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone Regeneration
Ceramics
Bone
Bone and Bones
78 Citations (Scopus)

Bio-inspired stable antimicrobial peptide coatings for dental applications

Holmberg, K. V., Abdolhosseini, M., Li, Y., Chen, X., Gorr, S-U. & Aparicio, C., Sep 1 2013, In : Acta Biomaterialia. 9, 9, p. 8224-8231 8 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Titanium
Peptides
Orthopedics
Tooth
22 Citations (Scopus)

Discerning the Subfibrillar Structure of Mineralized Collagen Fibrils: A Model for the Ultrastructure of Bone

Li, Y. & Aparicio, C., Sep 23 2013, In : PloS one. 8, 9, e76782.

Research output: Contribution to journalArticle

collagen
ultrastructure
Bone
Collagen
bones
51 Citations (Scopus)

Surface biofunctionalization by covalent co-immobilization of oligopeptides

Chen, X., Sevilla, P. & Aparicio, C., Jul 1 2013, In : Colloids and Surfaces B: Biointerfaces. 107, p. 189-197 9 p.

Research output: Contribution to journalArticle

Oligopeptides
immobilization
Immobilization
prolyl-histidyl-seryl-arginyl-asparagine
Coatings
2012
30 Citations (Scopus)

Adsorption of fibronectin, fibrinogen, and albumin on TiO2: time-resolved kinetics, structural changes, and competition study.

Pegueroles, M., Tonda-Turo, C., Planell, J. A., Gil, F. J. & Aparicio, C., Dec 2012, In : Biointerphases. 7, 1-4, p. 1-13 13 p.

Research output: Contribution to journalArticle

fibrinogen
albumins
Fibronectins
Fibrinogen
Adsorption
11 Citations (Scopus)

A novel dentin bond strength measurement technique using a composite disk in diametral compression

Huang, S. H., Lin, L. S., Rudney, J. D., Jones, R. S., Aparicio, C., Lin, C. P. & Fok, A., Apr 1 2012, In : Acta Biomaterialia. 8, 4, p. 1597-1602 6 p.

Research output: Contribution to journalArticle

Dentin
Acoustic emissions
Compaction
Resins
Specimen preparation
44 Citations (Scopus)

A reproducible oral microcosm biofilm model for testing dental materials

Rudney, J. D., Chen, R., Lenton, P. A., Li, J., Li, Y., Jones, R. S., Reilly, C. S., Fok, A. & Aparicio, C., Dec 1 2012, In : Journal of Applied Microbiology. 113, 6, p. 1540-1553 14 p.

Research output: Contribution to journalArticle

Dental Materials
Biofilms
Saliva
Sucrose
Durapatite