Christopher McGregor

1976 …2019

Research output per year

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Research Output

2019

A Durable Porcine Pericardial Surgical Bioprosthetic Heart Valve: a Proof of Concept

Rahmani, B., McGregor, C., Byrne, G. & Burriesci, G., Aug 15 2019, In : Journal of cardiovascular translational research. 12, 4, p. 331-337 7 p.

Research output: Contribution to journalArticle

Open Access
2018

B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen

Byrne, G., Ahmad-Villiers, S., Du, Z. & McGregor, C., Sep 1 2018, In : Xenotransplantation. 25, 5, e12394.

Research output: Contribution to journalReview article

Open Access
19 Scopus citations

Individualized surgical strategies for left ventricular outflow tract obstruction in hypertrophic cardiomyopathy

Collis, R., Tsang, V., Pantazis, A., Tome-Esteban, M., Elliott, P. M. & McGregor, C. G. A., Jun 1 2018, In : European Journal of Cardio-thoracic Surgery. 53, 6, p. 1237-1243 7 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Long-term outcomes for different surgical strategies to treat left ventricular outflow tract obstruction in hypertrophic cardiomyopathy

Collis, R., Watkinson, O., O'Mahony, C., Guttmann, O. P., Pantazis, A., Tome-Esteban, M., Tsang, V., Chandrasekaran, V., McGregor, C. G. A. & Elliott, P. M., Feb 1 2018, In : European Journal of Heart Failure. 20, 2, p. 398-405 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

PERVading strategies and infectious risk for clinical xenotransplantation

McGregor, C. G. A., Takeuchi, Y., Scobie, L. & Byrne, G., Jul 1 2018, In : Xenotransplantation. 25, 4, e12402.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations

Prosthesis type for aortic-and mitral-valve replacement

McGregor, C. G. A. & Byrne, G. W., Feb 22 2018, In : New England Journal of Medicine. 378, 8, p. 776-777 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

Proteomic Analysis of the Myocardium in Hypertrophic Obstructive Cardiomyopathy

Coats, C. J., Heywood, W. E., Virasami, A., Ashrafi, N., Syrris, P., Dos Remedios, C., Treibel, T. A., Moon, J. C., Lopes, L. R., McGregor, C. G. A., Ashworth, M., Sebire, N. J., McKenna, W. J., Mills, K. & Elliott, P. M., Dec 1 2018, In : Circulation. Genomic and precision medicine. 11, 12, p. e001974

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2017

An acquired Gerbode defect from the left ventricle to the coronary sinus following mitral valve replacement

Collis, R., Afoke, J. & McGregor, C. G. A., Jun 2017, In : Journal of Cardiac Surgery. 32, 6, p. 361-363 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Early and medium-term outcomes of Alfieri mitral valve repair in the management of systolic anterior motion during septal myectomy

Collis, R., Watkinson, O., Pantazis, A., Tome-Esteban, M., Elliott, P. M. & McGregor, C. G. A., Nov 2017, In : Journal of Cardiac Surgery. 32, 11, p. 686-690 5 p.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access
12 Scopus citations
2016

Physical equivalency of wild type and galactose α 1,3 galactose free porcine pericardium; a new source material for bioprosthetic heart valves

McGregor, C., Byrne, G., Rahmani, B., Chisari, E., Kyriakopoulou, K. & Burriesci, G., Sep 1 2016, In : Acta Biomaterialia. 41, p. 204-209 6 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2015

A pig-to-mouse coronary artery transplantation model for investigating the pathogenicity of anti-pig antibody

Lin, Y., Miyagi, N., Byrne, G. W., Du, Z., Kogelberg, H., Gazi, M. H., Tazelaar, H. D., Wang, C. & McGregor, C. G. A., Nov 1 2015, In : Xenotransplantation. 22, 6, p. 458-467 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Current status of pig heart xenotransplantation

Mohiuddin, M. M., Reichart, B., Byrne, G. W. & McGregor, C. G. A., Nov 1 2015, In : International Journal of Surgery. 23, p. 234-239 6 p.

Research output: Contribution to journalReview article

Open Access
35 Scopus citations

Pre-clinical heterotopic intrathoracic heart xenotransplantation: A possibly useful clinical technique

Abicht, J. M., Mayr, T., Reichart, B., Buchholz, S., Werner, F., Lutzmann, I., Schmoeckel, M., Bauer, A., Thormann, M., Langenmayer, M., Herbach, N., Pohla, H., Herzog, R., McGregor, C. G. A., Ayares, D., Wolf, E., Klymiuk, N., Baehr, A., Kind, A., Hagl, C. & 4 others, Ganswindt, U., Belka, C., Guethoff, S. & Brenner, P., Nov 1 2015, In : Xenotransplantation. 22, 6, p. 427-442 16 p.

Research output: Contribution to journalArticle

15 Scopus citations

Recent investigations into pig antigen and anti-pig antibody expression

Byrne, G. W., McGregor, C. G. A. & Breimer, M. E., Nov 1 2015, In : International Journal of Surgery. 23, p. 223-228 6 p.

Research output: Contribution to journalReview article

Open Access
36 Scopus citations
2014

A retrospective analysis of myocardial preservation techniques during coronary artery bypass graft surgery: Are we protecting the heart?

Candilio, L., Malik, A., Ariti, C., Khan, S. A., Barnard, M., Di Salvo, C., Lawrence, D. R., Hayward, M. P., Yap, J. A., Sheikh, A. M., McGregor, C. G. A., Kolvekar, S. K., Hausenloy, D. J., Yellon, D. M. & Roberts, N., Dec 31 2014, In : Journal of Cardiothoracic Surgery. 9, 1, 184.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen

Byrne, G. W., Du, Z., Stalboerger, P., Kogelberg, H. & McGregor, C. G. A., Nov 1 2014, In : Xenotransplantation. 21, 6, p. 543-554 12 p.

Research output: Contribution to journalArticle

Open Access
66 Scopus citations

Development of a consensus protocol to quantify primate anti-non-Gal xenoreactive antibodies using pig aortic endothelial cells

Azimzadeh, A. M., Byrne, G. W., Ezzelarab, M., Welty, E., Braileanu, G., Cheng, X., Robson, S. C., McGregor, C. G. A., Cooper, D. K. C. & Pierson, R. N., Nov 1 2014, In : Xenotransplantation. 21, 6, p. 555-566 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
4 Scopus citations
2013

Gal-knockout bioprostheses exhibit less immune stimulation compared to standard biological heart valves.

McGregor, C. G. A., Kogelberg, H., Vlasin, M. & Byrne, G. W., May 2013, In : The Journal of heart valve disease. 22, 3, p. 383-390 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Histopathologic insights into the mechanism of anti-non-Gal antibody-mediated pig cardiac xenograft rejection

Byrne, G. W., Azimzadeh, A. M., Ezzelarab, M., Tazelaar, H. D., Ekser, B., Pierson, R. N., Robson, S. C., Cooper, D. K. C. & McGregor, C. G. A., Sep 2013, In : Xenotransplantation. 20, 5, p. 292-307 16 p.

Research output: Contribution to journalReview article

12 Scopus citations

Somatic MYH7, MYBPC3, TPM1, TNNT2 and TNNI3 mutations in sporadic hypertrophic cardiomyopathy

Núñez, L., Gimeno-Blanes, J. R., Rodríguez-García, M. I., Monserrat, L., Zorio, E., Coats, C., McGregor, C. G., Hernandez del Rincón, J. P., Castro-Beiras, A. & Hermida-Prieto, M., 2013, In : Circulation Journal. 77, 9, p. 2358-2365 8 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

The mitochondrial permeability transition pore as a target for cardioprotection in hypertrophic cardiomyopathy

Rees, P. S. C., Davidson, S. M., Harding, S. E., McGregor, C., Elliot, P. M., Yellon, D. M. & Hausenloy, D. J., Jun 2013, In : Cardiovascular Drugs and Therapy. 27, 3, p. 235-237 3 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012
1 Scopus citations

Cardiac xenotransplantation: Progress and challenges

Byrne, G. W. & McGregor, C. G. A., Apr 2012, In : Current Opinion in Organ Transplantation. 17, 2, p. 148-154 7 p.

Research output: Contribution to journalReview article

35 Scopus citations

Human CD55 expression blocks hyperacute rejection and restricts complement activation in gal knockout cardiac xenografts

McGregor, C. G. A., Ricci, D., Miyagi, N., Stalboerger, P. G., Du, Z., Oehler, E. A., Tazelaar, H. D. & Byrne, G. W., Apr 15 2012, In : Transplantation. 93, 7, p. 686-692 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Seligman's theory of attributional style: Optimism, pessimism, and quality of life after heart transplant

Jowsey, S., Cutshall, S., Colligan, R., Stevens, S., Kremers, W., Vasquez, A., Edwards, B., Daly, R. & McGregor, C., Mar 1 2012, In : Progress in Transplantation. 22, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

State-of-the-art implantable cardiac assist device therapy for heart failure: Bridge to transplant and destination therapy

Park, S. J., Kushwaha, S. S. & McGregor, C. G. A., Jan 2012, In : Clinical pharmacology and therapeutics. 91, 1, p. 94-100 7 p.

Research output: Contribution to journalReview article

8 Scopus citations
2011

Cardiac xenotransplantation technology provides materials for improved bioprosthetic heart valves

McGregor, C. G. A., Carpentier, A., Lila, N., Logan, J. S. & Byrne, G. W., Jan 1 2011, In : Journal of Thoracic and Cardiovascular Surgery. 141, 1, p. 269-275 7 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Changes in cardiac gene expression after pig-to-primate orthotopic xenotransplantation

Byrne, G. W., Du, Z., Sun, Z., Asmann, Y. W. & McGregor, C. G. A., Jan 2011, In : Xenotransplantation. 18, 1, p. 14-27 14 p.

Research output: Contribution to journalArticle

29 Scopus citations

Coagulopathy in α-galactosyl transferase knockout pulmonary xenotransplants

Bush, E. L., Barbas, A. S., Holzknecht, Z. E., Byrne, G. W., McGregor, C. G., Parker, W., Davis, R. D. & Lin, S. S., Jan 2011, In : Xenotransplantation. 18, 1, p. 6-13 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Combined heart and kidney transplantation provides an excellent survival and decreases risk of cardiac cellular rejection and coronary allograft vasculopathy

Raichlin, E., Kushwaha, S. S., Daly, R. C., Kremers, W. K., Frantz, R. P., Clavell, A. L., Rodeheffer, R. J., Larson, T. S., Stegall, M. D., McGregor, C., Pereira, N. L. & Edwards, B. S., Jun 1 2011, In : Transplantation proceedings. 43, 5, p. 1871-1876 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Comparison of gal and non-gal-mediated cardiac xenograft rejection

Tazelaar, H. D., Byrne, G. W. & McGregor, C. G. A., May 15 2011, In : Transplantation. 91, 9, p. 968-975 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Identification of new carbohydrate and membrane protein antigens in cardiac Xenotransplantation

Byrne, G. W., Stalboerger, P. G., Du, Z., Davis, T. R. & McGregor, C. G. A., Feb 15 2011, In : Transplantation. 91, 3, p. 287-292 6 p.

Research output: Contribution to journalArticle

70 Scopus citations

Mitral valve regurgitation in patients supported on continuous flow pumps

Topilsky, Y., Hasin, T., McGregor, C. G. A. & Park, S. J., Nov 1 2011, In : Echocardiography. 28, 10, p. E202-E204

Research output: Contribution to journalArticle

2 Scopus citations

Pathophysiological changes after cardiac transplantation: The role of chronic inflammation and rejection

Boilson, B. A., McGregor, C. G. A. & Kushwaha, S. S., Oct 2011, In : Heart. 97, 20, p. 1634-1635 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Reply to the Editor

McGregor, C. G. A., Carpentier, A., Lila, N., Logan, J. S. & Byrne, G. W., Jul 1 2011, In : Journal of Thoracic and Cardiovascular Surgery. 142, 1, 1 p.

Research output: Contribution to journalLetter

Open Access

Who should treat coronary left main disease - A battle of the Titans?

Meier, P., Lansky, A. J. & Mcgregor, C. G. A., Jul 2011, In : Cardiology. 118, 4, p. 233-235 3 p.

Research output: Contribution to journalComment/debate

2010

B-Type natriuretic peptide levels and continuous-flow left ventricular assist devices

Sareyyupoglu, B., Boilson, B. A., Durham, L. A., McGregor, C. G. A., Daly, R. C., Redfield, M. M., Edwards, B. S., Frantz, R. P., Pereira, N. L. & Park, S. J., Nov 1 2010, In : ASAIO Journal. 56, 6, p. 527-531 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Concomitant surgery for renal neoplasm with pulmonary tumor embolism

Kayalar, N., Leibovich, B. C., Orszulak, T. A., Schaff, H. V., Sundt, T. M., Daly, R. C. & McGregor, C. G. A., Feb 1 2010, In : Journal of Thoracic and Cardiovascular Surgery. 139, 2, p. 320-325 6 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Equilibrium contrast cardiovascular magnetic resonance for the measurement of diffuse myocardial fibrosis: Preliminary validation in humans

Flett, A. S., Hayward, M. P., Ashworth, M. T., Hansen, M. S., Taylor, A. M., Elliott, P. M., McGregor, C. & Moon, J. C., Jul 13 2010, In : Circulation. 122, 2, p. 138-144 7 p.

Research output: Contribution to journalArticle

Open Access
566 Scopus citations

Equilibrium contrast CMR for the measurement of diffuse myocardial fibrosis

Flett, A. S., Harward, M., Ashworth, M. T., Hansen, M. S., Taylor, A. M., Kolvekar, S., Yap, J., Elliott, P., McGregor, C. & Moon, J. C., 2010, In : Journal of Cardiovascular Magnetic Resonance. 12, SUPPL. 1, O16.

Research output: Contribution to journalArticle

Open Access

Gal knockout pig pericardium: New source of material for heart valve bioprostheses

Lila, N., McGregor, C. G. A., Carpentier, S., Rancic, J., Byrne, G. W. & Carpentier, A., May 1 2010, In : Journal of Heart and Lung Transplantation. 29, 5, p. 538-543 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

High serum cholesterol levels are associated with herpes zoster infection after heart transplantation

Del Pozo, J. L., Van De Beek, D., Mandrekar, J. N., Daly, R. C., McGregor, C. G. A., Azanza, J. R. & Patel, R., Jan 2010, In : Clinical Infectious Diseases. 50, 1, p. 121-122 2 p.

Research output: Contribution to journalLetter

Open Access
10 Scopus citations

Myectomy plus alfieri technique for outflow tract obstruction in hypertrophic cardiomyopathy

Sado, D. M., Flett, A. S., McGregor, C. G. A., Pantazis, A. A., Elliott, P. M. & Moon, J. C., Aug 31 2010, In : Circulation. 122, 9, p. 938-939 2 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Prolonged Cardiac Allograft Survival Using Iodine 131 After Human Sodium Iodide Symporter Gene Transfer in A Rat Model

Ricci, D., Mennander, A. A., Miyagi, N., Rao, V. P., Tazelaar, H. D., Classic, K., Byrne, G. W., Russell, S. J. & McGregor, C. G. A., Jun 1 2010, In : Transplantation proceedings. 42, 5, p. 1888-1894 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pulmonary thromboendarterectomy in adolescents and young adults

Johnson, J. N., Driscoll, D. J. & McGregor, C. G. A., Jun 2010, In : Pediatric pulmonology. 45, 6, p. 614-618 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pulmonary thromboendarterectomy in Klippel-Trénaunay syndrome

Johnson, J. N., Driscoll, D. J. & McGregor, C. G. A., Sep 1 2010, In : Journal of Thoracic and Cardiovascular Surgery. 140, 3, p. e41-e43

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Rat model in the study of the role of α-gal in heart valve bioprostheses calcification

Lila, N., McGregor, C. G. A., Byrne, G. W. & Carpentier, A., May 20 2010, In : Journal of Heart and Lung Transplantation. 29, 8, p. 912-913 2 p.

Research output: Contribution to journalLetter

2009

Acute Cellular Rejection and the Subsequent Development of Allograft Vasculopathy After Cardiac Transplantation

Raichlin, E., Edwards, B. S., Kremers, W. K., Clavell, A. L., Rodeheffer, R. J., Frantz, R. P., Pereira, N. L., Daly, R. C., McGregor, C. G., Lerman, A. & Kushwaha, S. S., Apr 1 2009, In : Journal of Heart and Lung Transplantation. 28, 4, p. 320-327 8 p.

Research output: Contribution to journalArticle

98 Scopus citations