1990 …2025
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1990 2020

Filter
Article
2020

CD200 checkpoint reversal: A novel approach to immunotherapy a C

Xiong, Z., Mesias, E. A., Elizabeth Pluhar, G., Rathe, S. K., Largaespada, D. A., Sham, Y. Y., Moertel, C. L. & Olin, M. R., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 232-241 10 p.

Research output: Contribution to journalArticle

Open Access
Immunotherapy
Peptides
Cancer Vaccines
Glioblastoma
Chemokines
2019
3 Citations (Scopus)
Neurofibromatosis 2
Hearing
Tumor Burden
Dysgeusia
Aptitude
Noonan Syndrome
Neurofibromatoses
Neurofibromatosis 1
Siblings
Attention Deficit Disorder with Hyperactivity
2 Citations (Scopus)
Open Access
Pets
Glioma
Vaccination
Dogs
Antigen-Presenting Cells
2018
4 Citations (Scopus)

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1

Isakson, S. H., Rizzardi, A. E., Coutts, A. W., Carlson, D. F., Kirstein, M. N., Fisher, J., Vitte, J., Williams, K. B., Pluhar, G. E., Dahiya, S., Widemann, B. C., Dombi, E., Rizvi, T., Ratner, N., Messiaen, L., Stemmer-Rachamimov, A. O., Fahrenkrug, S. C., Gutmann, D. H., Giovannini, M., Moertel, C. L. & 2 others, Largaespada, D. A. & Watson, A. L., Dec 1 2018, In : Communications biology. 1, 1, 158.

Research output: Contribution to journalArticle

Open Access
Miniature Swine
Neurofibromatosis 1
mitogen-activated protein kinase
Neurofibromin 1
genetic disorders

Predictive Value and Interrater Reliability of Radiographic Factors in Neurofibromatosis Patients With Dystrophic Scoliosis

Larson, A. N., Ledonio, C. G. T., Brearley, A. M., Sucato, D. J., Carreon, L. Y., Crawford, A. H., Stevenson, D. A., Vitale, M. G., Moertel, C. L. & Polly, D. W., Sep 1 2018, In : Spine Deformity. 6, 5, p. 560-567 8 p.

Research output: Contribution to journalArticle

Open Access
Neurofibromatoses
Scoliosis
Ribs
Spine
Neurofibromatosis 1
5 Citations (Scopus)
Open Access
Noonan Syndrome
Neurofibromatosis 1
Language
Attention Deficit Disorder with Hyperactivity
Siblings
2017
5 Citations (Scopus)
Extracellular Signal-Regulated MAP Kinases
Mitogen-Activated Protein Kinases
Skin
Neoplasms
Acneiform Eruptions
Glioma
Respiratory Insufficiency
Astrocytoma
Respiratory Sounds
Palliative Care
9 Citations (Scopus)

Phase I trial of low-dose interleukin 2 therapy in patients with Wiskott-Aldrich syndrome

Jyonouchi, S., Gwafila, B., Gwalani, L. A., Ahmad, M., Moertel, C., Holbert, C., Kim, J. Y., Kobrinsky, N., Roy-Ghanta, S. & Orange, J. S., Jun 1 2017, In : Clinical Immunology. 179, p. 47-53 7 p.

Research output: Contribution to journalArticle

Wiskott-Aldrich Syndrome
Interleukin-2
Natural Killer Cells
Therapeutics
T-Lymphocytes
11 Citations (Scopus)
Astrocytoma
Documentation
Pediatrics
Mitogens
Neoplasms
9 Citations (Scopus)

SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors

Higham, C. S., Steinberg, S. M., Dombi, E., Perry, A., Helman, L. J., Schuetze, S. M., Ludwig, J. A., Staddon, A., Milhem, M. M., Rushing, D., Jones, R. L., Livingston, M., Goldman, S., Moertel, C., Wagner, L., Janhofer, D., Annunziata, C. M., Reinke, D., Long, L., Viskochil, D. & 2 others, Baker, L. & Widemann, B. C., Jan 1 2017, In : Sarcoma. 2017, 8685638.

Research output: Contribution to journalArticle

Open Access
Neurofibromatosis 1
Neurilemmoma
Drug Therapy
Ifosfamide
Etoposide
2016
Mucopolysaccharidoses
Glycosaminoglycans
Neuroblastoma
Urine
Ganglioneuroblastoma
5 Citations (Scopus)

Tumor-derived vaccines containing CD200 inhibit immune activation: Implications for immunotherapy

Xiong, Z., Ampudia-Mesias, E., Shaver, R., Horbinski, C. M., Moertel, C. L. & Olin, M. R., Sep 2016, In : Immunotherapy. 8, 9, p. 1059-1071 13 p.

Research output: Contribution to journalArticle

Immune Tolerance
Cancer Vaccines
Immunotherapy
Vaccines
Antigen-Presenting Cells
2015

A blurry differential. Optic neuritis leads down a treacherous slope

Mapellentz, J., Fansler, M., Orozco, J., Nascene, D., Linden, M. & Moertel, C., May 1 2015, In : Minnesota medicine. 98, 5, 1 p.

Research output: Contribution to journalArticle

Paraneoplastic Syndromes
Optic Neuritis
Vision Disorders
Hodgkin Disease
Disease Progression
18 Citations (Scopus)
Missense Mutation
Phenotype
Neurilemmoma
Mutation
Hirsutism
2014
4 Citations (Scopus)

A novel APC gene mutation associated with a severe phenotype in a patient with Turcot syndrome

Fritch Lilla, S. A., Yi, J. S., Hall, B. A. C. & Moertel, C. L., Apr 2014, In : Journal of Pediatric Hematology/Oncology. 36, 3

Research output: Contribution to journalArticle

APC Genes
Phenotype
Sarcoma
Mutation
Pilomatrixoma
16 Citations (Scopus)

CD200 in CNS tumor-induced immunosuppression: The role for CD200 pathway blockade in targeted immunotherapy

Moertel, C. L., Xia, J., LaRue, R., Waldron, N. N., Andersen, B. M., Prins, R. M., Okada, H., Donson, A. M., Foreman, N. K., Hunt, M. A., Pennell, C. A. & Olin, M. R., Dec 16 2014, In : Journal for ImmunoTherapy of Cancer. 2, 1, 46.

Research output: Contribution to journalArticle

Central Nervous System Neoplasms
Immunotherapy
Immunosuppression
Brain Neoplasms
Glioblastoma
41 Citations (Scopus)

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity

Watson, A. L., Anderson, L. K., Greeley, A. D., Keng, V. W., Rahrmann, E. P., Halfond, A. L., Powell, N. M., Collins, M. H., Rizvi, T., Moertel, C. L., Ratner, N. & Largaespada, D. A., 2014, In : Oncotarget. 5, 6, p. 1502-1514 13 p.

Research output: Contribution to journalArticle

Schwann Cells
Neurilemmoma
Phosphatidylinositol 3-Kinases
Neurofibromatosis 1
Plexiform Neurofibroma
41 Citations (Scopus)

Pilomyxoid astrocytoma treated successfully with vemurafenib

Skrypek, M., Foreman, N., Guillaume, D. & Moertel, C., Nov 1 2014, In : Pediatric Blood and Cancer. 61, 11, p. 2099-2100 2 p.

Research output: Contribution to journalArticle

Astrocytoma
Proto-Oncogene Proteins B-raf
Central Nervous System Neoplasms
Neoplasms
Vinblastine
11 Citations (Scopus)
Maintenance
Drug Therapy
Pediatrics
Giant Lymph Node Hyperplasia
Interleukin-6 Receptors
23 Citations (Scopus)
Brain Neoplasms
Dendritic Cells
Vaccination
Vaccines
Subcutaneous Injections
4 Citations (Scopus)
Active Immunotherapy
Brain Neoplasms
Canidae
Neoplasms
Immunotherapy
2013
92 Citations (Scopus)

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

Rahrmann, E. P., Watson, A. L., Keng, V. W., Choi, K., Moriarity, B. S., Beckmann, D. A., Wolf, N. K., Sarver, A., Collins, M. H., Moertel, C. L., Wallace, M. R., Gel, B., Serra, E., Ratner, N. & Largaespada, D. A., Jul 1 2013, In : Nature Genetics. 45, 7, p. 756-766 11 p.

Research output: Contribution to journalArticle

Neurilemmoma
Carcinogenesis
Proto-Oncogenes
Genes
Beauty
40 Citations (Scopus)

Outcome of infants and young children with newly diagnosed ependymoma treated on the "head Start" III prospective clinical trial

Venkatramani, R., Ji, L., Lasky, J., Haley, K., Judkins, A., Zhou, S., Sposto, R., Olshefski, R., Garvin, J., Tekautz, T., Kennedy, G., Rassekh, S. R., Moore, T., Gardner, S., Allen, J., Shore, R., Moertel, C., Atlas, M., Dhall, G. & Finlay, J., Jun 1 2013, In : Journal of neuro-oncology. 113, 2, p. 285-291 7 p.

Research output: Contribution to journalArticle

Ependymoma
Clinical Trials
Induction Chemotherapy
Disease-Free Survival
Consolidation Chemotherapy
2012
38 Citations (Scopus)

PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors

Keng, V. W., Rahrmann, E. P., Watson, A. L., Tschida, B. R., Moertel, C. L., Jessen, W. J., Rizvi, T. A., Collins, M. H., Ratner, N. & Largaespada, D. A., Jul 1 2012, In : Cancer Research. 72, 13, p. 3405-3413 9 p.

Research output: Contribution to journalArticle

Neurofibroma
Neurofibromatosis 1
Schwann Cells
Neurilemmoma
Peripheral Nervous System
2010

Primary autoimmune neutropenia uncovered by methicillin-resistant staphylococcus aureus osteomyelitis

Kunkel, M. A., Moertel, C. L. & John, C. C., Jul 1 2010, In : Infectious Diseases in Clinical Practice. 18, 4, p. 279-280 2 p.

Research output: Contribution to journalArticle

Osteomyelitis
Methicillin-Resistant Staphylococcus aureus
Neutropenia
Infection
4 Citations (Scopus)

Pseudometastasis secondary to histoplasmosis infection: False-positive PET/CT findings

Perko, R., Messinger, Y. & Moertel, C., Apr 1 2010, In : Pediatric Blood and Cancer. 54, 4, p. 621-623 3 p.

Research output: Contribution to journalArticle

Emission-Computed Tomography
Histoplasmosis
Positron-Emission Tomography
Infection
Itraconazole
2009
31 Citations (Scopus)

Homozygous α-Thalassemia Treated with Intrauterine Transfusions and Unrelated Donor Hematopoietic Cell Transplantation

Yi, J. S., Moertel, C. L. & Baker, K. S., May 1 2009, In : Journal of Pediatrics. 154, 5, p. 766-768 3 p.

Research output: Contribution to journalArticle

Intrauterine Blood Transfusion
Unrelated Donors
Thalassemia
Cell Transplantation
alpha-Thalassemia
2008
21 Citations (Scopus)

Treatment of recurrent clear cell sarcoma of the kidney with brain metastasis

Radulescu, V. C., Gerrard, M., Moertel, C., Grundy, P. E., Mathias, L., Feusner, J., Diller, L. & Dome, J. S., Feb 1 2008, In : Pediatric Blood and Cancer. 50, 2, p. 246-249 4 p.

Research output: Contribution to journalArticle

Clear Cell Sarcoma
Neoplasm Metastasis
Kidney
Drug Therapy
Brain
2007
47 Citations (Scopus)

Cerebral metastasis and other central nervous system complications of pleuropulmonary blastoma

Priest, J. R., Magnuson, J., Williams, G. M., Abromowitch, M., Byrd, R., Sprinz, P., Finkelstein, M., Moertel, C. L. & Hill, D. A., Sep 1 2007, In : Pediatric Blood and Cancer. 49, 3, p. 266-273 8 p.

Research output: Contribution to journalArticle

Central Nervous System
Neoplasm Metastasis
Registries
Second Primary Neoplasms
Pleuropulmonary blastoma
2006
81 Citations (Scopus)

Type I pleuropulmonary blastoma: A report from the international pleuropulmonary blastoma registry

Priest, J. R., Hill, D. A., Williams, G. M., Moertel, C. L., Messinger, Y., Finkelstein, M. J. & Dehner, L. P., Sep 20 2006, In : Journal of Clinical Oncology. 24, 27, p. 4492-4498 7 p.

Research output: Contribution to journalArticle

Registries
Recurrence
Adjuvant Chemotherapy
Drug Therapy
Survival
2004
43 Citations (Scopus)

Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2

Widemann, B. C., Balis, F. M., Shalabi, A., Boron, M., O'Brien, M., Cole, D. E., Jayaprakash, N., Ivy, P., Castle, V., Muraszko, K., Moertel, C. L., Trueworthy, R., Hermann, R. C., Moussa, A., Hinton, S., Reaman, G., Poplack, D. & Adamson, P. C., Oct 20 2004, In : Journal of the National Cancer Institute. 96, 20, p. 1557-1559 3 p.

Research output: Contribution to journalArticle

gamma-Glutamyl Hydrolase
Methotrexate
Cerebrospinal Fluid
Therapeutics
Coma
2001
3 Citations (Scopus)

Acute polyosteal osteomyelitis in a patient with congenital ichthyosis and acute lymphoblastic leukemia

Tolar, J., Kravitz, G., Walker, K. & Moertel, C. L., Jan 1 2001, In : Pediatric Infectious Disease Journal. 20, 8, p. 813-814 2 p.

Research output: Contribution to journalArticle

Ichthyosis
Osteomyelitis
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Induction Chemotherapy
Bacteremia
31 Citations (Scopus)

Eosinophil-associated inflammation and elaboration of eosinophil-derived proteins in 2 children with raccoon roundworm (Baylisascaris procyonis) encephalitis.

Moertel, C. L., Kazacos, K. R., Butterfield, J. H., Kita, H., Watterson, J. & Gleich, G. J., Nov 2001, In : Pediatrics. 108, 5, p. E93

Research output: Contribution to journalArticle

Ascaridoidea
Eosinophil-Derived Neurotoxin
Raccoons
Encephalitis
Eosinophils
14 Citations (Scopus)

Lymphomatoid granulomatosis after childhood acute lymphoblastic leukemia: report of effective therapy.

Moertel, C. L., Carlson-Green, B., Watterson, J. & Simonton, S. C., May 2001, In : Pediatrics. 107, 5

Research output: Contribution to journalArticle

Lymphomatoid Granulomatosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Splenomegaly
Lung
Therapeutics
1998
32 Citations (Scopus)

Treatment of intermediate risk rhabdomyosarcoma and undifferentiated sarcoma with alternating cycles of vincristine/doxorubicin/cyclophosphamide and etoposide/ifosfamide

Arndt, C. A. S., Nascimento, A. G., Schroeder, G., Schomberg, P. J., Neglia, J. P., Sencer, S. F., Silberman, T. L., Moertel, C. L., Tillisch, J. K. & Miser, J. S., Jul 1 1998, In : European Journal of Cancer. 34, 8, p. 1224-1229 6 p.

Research output: Contribution to journalArticle

Ifosfamide
Rhabdomyosarcoma
Vincristine
Etoposide
Sarcoma
213 Citations (Scopus)

Whole blood tissue factor procoagulant activity is elevated in patients with sickle cell disease

Key, N. S., Slungaard, A., Dandelet, L., Nelson, S. C., Moertel, C., Styles, L. A., Kuypers, F. A. & Bach, R. R., Jun 1 1998, In : Blood. 91, 11, p. 4216-4223 8 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Thromboplastin
Blood
Plasmas
Hemoglobin SC Disease
1997
13 Citations (Scopus)

One course versus two courses of antithymocyte globulin for the treatment of severe aplastic anemia in children

Matloub, Y. H., Smith, C., Bostrom, B., Koerper, M. A., O’Leary, M., Khuder, S., Smithson, W. A., Nickerson, H. J., Silberman, T., Hilden, J., Moertel, C. L., Month, S., Monteleone, P. & Ramsay, N. K. C., Jan 1 1997, In : American Journal of Pediatric Hematology/Oncology. 19, 2, p. 110-114 5 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
Aplastic Anemia
Therapeutics
Immunosuppressive Agents
Prednisone
17 Citations (Scopus)

Retinal toxicity associated with cisplatin and etoposide in pediatric patients

Hilliard, L. M., Berkow, R. L., Watterson, J., Ballard, E. A., Balzer, G. K. & Moertel, C. L., Apr 1 1997, In : Medical and Pediatric Oncology. 28, 4, p. 310-313 4 p.

Research output: Contribution to journalArticle

Etoposide
Cisplatin
Platinum
Pediatrics
Kidney
46 Citations (Scopus)

The use of implantable venous access devices (IVADs) in children with hemophilia

Perkins, J. L., Johnson, V. A., Osip, J. M., Christie, B. A., Nelson, S. C., Moertel, C. L. & Heisel, M. A., Jan 1 1997, In : American Journal of Pediatric Hematology/Oncology. 19, 4, p. 339-344 6 p.

Research output: Contribution to journalArticle

Hemophilia A
Equipment and Supplies
Infection
Thrombophlebitis
Bacteremia
1996
159 Citations (Scopus)

Lupus anticoagulant and protein S deficiency in children with postvaricella purpura fulminans or thrombosis

Manco-Johnson, M. J., Nuss, R., Key, N., Moertel, C., Jacobson, L., Meech, S., Weinberg, A. & Lefkowitz, J., Jan 1 1996, In : Journal of Pediatrics. 128, 3, p. 319-323 5 p.

Research output: Contribution to journalArticle

Purpura Fulminans
Protein S Deficiency
Lupus Coagulation Inhibitor
Thrombosis
Protein S
1 Citation (Scopus)

Serologic evidence that factor IX inhibitor in the plasma of hemophilia B patients detects factor IX on normal red cells

Swanson, J. L., Moertel, C. L., Stroncek, D. F. & Key, N. S., Jan 1 1996, In : Transfusion. 36, 5, p. 467-469 3 p.

Research output: Contribution to journalArticle

Hemophilia B
Factor IX
Siblings
Antibodies
Serum
23 Citations (Scopus)

Stereotactic radiosurgery in pediatric patients

Weprin, B. E., Hall, W. A., Cho, K. H., Sperduto, P. W., Gerbi, B. J. & Moertel, C. L., Oct 1 1996, In : Pediatric Neurology. 15, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

Radiosurgery
Pediatrics
Arteriovenous Malformations
Neoplasms
Radiation Injuries
1995
31 Citations (Scopus)

Follicular large cell lymphoma of the testis in a child

Moertel, C. L., Watterson, J., McCormick, S. R. & Simonton, S. C., Mar 1 1995, In : Cancer. 75, 5, p. 1182-1186 5 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Gene Rearrangement
Testis
Southern Blotting
In Situ Hybridization
11 Citations (Scopus)

Use of intracavitary cisplatin for the treatment of childhood solid tumors in the chest or abdominal cavity

Boyer, M. W., Moertel, C. L., Priest, J. R. & Woods, W. G., Mar 1995, In : Journal of Clinical Oncology. 13, 3, p. 631-636 6 p.

Research output: Contribution to journalArticle

Abdominal Cavity
Cisplatin
Thorax
Neoplasms
Therapeutics
1994
73 Citations (Scopus)

Excessive spinal cord toxicity from intensive central nervous system ‐directed therapies

Watterson, J., Toogood, I., Nieder, M., Morse, M., Frierdich, S., Lee, Y., Moertel, C. L. & Priest, J. R., Dec 1 1994, In : Cancer. 74, 11, p. 3034-3041 8 p.

Research output: Contribution to journalArticle

Spinal Cord
Central Nervous System
Methotrexate
Spinal Cord Diseases
Thiotepa
59 Citations (Scopus)

Expression of somatostatin receptors in childhood neuroblastoma

Moertel, C. L., Reubi, J. C., Scheithauer, B. S., Schaid, D. J. & Kvols, L. K., Dec 1 1994, In : American journal of clinical pathology. 102, 6, p. 752-756 5 p.

Research output: Contribution to journalArticle

Somatostatin Receptors
Neuroblastoma
Neoplasms
Paraganglioma
Octreotide
1993
3 Citations (Scopus)

A complete ileo-tumor-colic fistula in a child with Burkitt's lymphoma

Moertel, C. L., Watterson, J., Drake, D. G., Johnson, K. W. & Brennom, W. S., Oct 1 1993, In : Pediatric Radiology. 23, 6, p. 467-468 2 p.

Research output: Contribution to journalArticle

Burkitt Lymphoma
Colic
Fistula
Ileum
Laparotomy
1992
2 Citations (Scopus)

Wilms' tumor: A new cause for urinary extravasation

Andrews, P. E., Hill, D. E., Moertel, C. L., Miser, J. S. & Lewis, B. D., May 1992, In : Journal of Pediatric Surgery. 27, 5, p. 660-661 2 p.

Research output: Contribution to journalArticle

Wilms Tumor
Neoplasms
Kidney Pelvis
Capsules
Urine