1990 …2025

Research output per year

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Research Output

2020

CD200 checkpoint reversal: A novel approach to immunotherapy a C

Xiong, Z., Mesias, E. A., Elizabeth Pluhar, G., Rathe, S. K., Largaespada, D. A., Sham, Y. Y., Moertel, C. L. & Olin, M. R., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 232-241 10 p.

Research output: Contribution to journalArticle

Open Access
2019
4 Scopus citations

Emotional functioning among children with neurofibromatosis type 1 or Noonan syndrome

McNeill, A. M., Hudock, R. L., Foy, A. M. H., Shanley, R., Semrud-Clikeman, M., Pierpont, M. E., Berry, S. A., Sommer, K., Moertel, C. L. & Pierpont, E. I., Dec 1 2019, In : American Journal of Medical Genetics, Part A. 179, 12, p. 2433-2446 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1

Isakson, S. H., Rizzardi, A. E., Coutts, A. W., Carlson, D. F., Kirstein, M. N., Fisher, J., Vitte, J., Williams, K. B., Pluhar, G. E., Dahiya, S., Widemann, B. C., Dombi, E., Rizvi, T., Ratner, N., Messiaen, L., Stemmer-Rachamimov, A. O., Fahrenkrug, S. C., Gutmann, D. H., Giovannini, M., Moertel, C. L. & 2 others, Largaespada, D. A. & Watson, A. L., Dec 1 2018, In : Communications biology. 1, 1, 158.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Predictive Value and Interrater Reliability of Radiographic Factors in Neurofibromatosis Patients With Dystrophic Scoliosis

Larson, A. N., Ledonio, C. G. T., Brearley, A. M., Sucato, D. J., Carreon, L. Y., Crawford, A. H., Stevenson, D. A., Vitale, M. G., Moertel, C. L. & Polly, D. W., Sep 1 2018, In : Spine Deformity. 6, 5, p. 560-567 8 p.

Research output: Contribution to journalArticle

Open Access
Open Access
6 Scopus citations
2017

An Unusual Pelvic Mass in a Pediatric Patient: A Case Report and Review of the Pathology

Bauman, B. D., Moertel, C. L., Zheng, E., Louiselle, A., Berdan, E., Berger, D. & Segura, B., Jan 1 2017, In : Journal of pediatric hematology/oncology. 39, 4, p. 306-308 3 p.

Research output: Contribution to journalReview article

2 Scopus citations
5 Scopus citations

Phase I trial of low-dose interleukin 2 therapy in patients with Wiskott-Aldrich syndrome

Jyonouchi, S., Gwafila, B., Gwalani, L. A., Ahmad, M., Moertel, C., Holbert, C., Kim, J. Y., Kobrinsky, N., Roy-Ghanta, S. & Orange, J. S., Jun 1 2017, In : Clinical Immunology. 179, p. 47-53 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
11 Scopus citations

SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors

Higham, C. S., Steinberg, S. M., Dombi, E., Perry, A., Helman, L. J., Schuetze, S. M., Ludwig, J. A., Staddon, A., Milhem, M. M., Rushing, D., Jones, R. L., Livingston, M., Goldman, S., Moertel, C., Wagner, L., Janhofer, D., Annunziata, C. M., Reinke, D., Long, L., Viskochil, D. & 2 others, Baker, L. & Widemann, B. C., Jan 1 2017, In : Sarcoma. 2017, 8685638.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2016

Tumor-derived vaccines containing CD200 inhibit immune activation: Implications for immunotherapy

Xiong, Z., Ampudia-Mesias, E., Shaver, R., Horbinski, C. M., Moertel, C. L. & Olin, M. R., Sep 2016, In : Immunotherapy. 8, 9, p. 1059-1071 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

A blurry differential. Optic neuritis leads down a treacherous slope

Mapellentz, J., Fansler, M., Orozco, J., Nascene, D., Linden, M. & Moertel, C., May 1 2015, In : Minnesota medicine. 98, 5, 1 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014

A novel APC gene mutation associated with a severe phenotype in a patient with Turcot syndrome

Fritch Lilla, S. A., Yi, J. S., Hall, B. A. C. & Moertel, C. L., Apr 2014, In : Journal of Pediatric Hematology/Oncology. 36, 3

Research output: Contribution to journalArticle

4 Scopus citations

CD200 in CNS tumor-induced immunosuppression: The role for CD200 pathway blockade in targeted immunotherapy

Moertel, C. L., Xia, J., LaRue, R., Waldron, N. N., Andersen, B. M., Prins, R. M., Okada, H., Donson, A. M., Foreman, N. K., Hunt, M. A., Pennell, C. A. & Olin, M. R., Dec 16 2014, In : Journal for ImmunoTherapy of Cancer. 2, 1, 46.

Research output: Contribution to journalArticle

18 Scopus citations

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity

Watson, A. L., Anderson, L. K., Greeley, A. D., Keng, V. W., Rahrmann, E. P., Halfond, A. L., Powell, N. M., Collins, M. H., Rizvi, T., Moertel, C. L., Ratner, N. & Largaespada, D. A., 2014, In : Oncotarget. 5, 6, p. 1502-1514 13 p.

Research output: Contribution to journalArticle

41 Scopus citations

Pilomyxoid astrocytoma treated successfully with vemurafenib

Skrypek, M., Foreman, N., Guillaume, D. & Moertel, C., Nov 1 2014, In : Pediatric Blood and Cancer. 61, 11, p. 2099-2100 2 p.

Research output: Contribution to journalArticle

41 Scopus citations
11 Scopus citations
24 Scopus citations
5 Scopus citations
2013

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

Rahrmann, E. P., Watson, A. L., Keng, V. W., Choi, K., Moriarity, B. S., Beckmann, D. A., Wolf, N. K., Sarver, A., Collins, M. H., Moertel, C. L., Wallace, M. R., Gel, B., Serra, E., Ratner, N. & Largaespada, D. A., Jul 1 2013, In : Nature Genetics. 45, 7, p. 756-766 11 p.

Research output: Contribution to journalArticle

95 Scopus citations

Outcome of infants and young children with newly diagnosed ependymoma treated on the "head Start" III prospective clinical trial

Venkatramani, R., Ji, L., Lasky, J., Haley, K., Judkins, A., Zhou, S., Sposto, R., Olshefski, R., Garvin, J., Tekautz, T., Kennedy, G., Rassekh, S. R., Moore, T., Gardner, S., Allen, J., Shore, R., Moertel, C., Atlas, M., Dhall, G. & Finlay, J., Jun 1 2013, In : Journal of neuro-oncology. 113, 2, p. 285-291 7 p.

Research output: Contribution to journalArticle

40 Scopus citations
2012

PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors

Keng, V. W., Rahrmann, E. P., Watson, A. L., Tschida, B. R., Moertel, C. L., Jessen, W. J., Rizvi, T. A., Collins, M. H., Ratner, N. & Largaespada, D. A., Jul 1 2012, In : Cancer Research. 72, 13, p. 3405-3413 9 p.

Research output: Contribution to journalArticle

38 Scopus citations
2010

Primary autoimmune neutropenia uncovered by methicillin-resistant staphylococcus aureus osteomyelitis

Kunkel, M. A., Moertel, C. L. & John, C. C., Jul 1 2010, In : Infectious Diseases in Clinical Practice. 18, 4, p. 279-280 2 p.

Research output: Contribution to journalArticle

Pseudometastasis secondary to histoplasmosis infection: False-positive PET/CT findings

Perko, R., Messinger, Y. & Moertel, C., Apr 1 2010, In : Pediatric Blood and Cancer. 54, 4, p. 621-623 3 p.

Research output: Contribution to journalArticle

4 Scopus citations
2009

Homozygous α-Thalassemia Treated with Intrauterine Transfusions and Unrelated Donor Hematopoietic Cell Transplantation

Yi, J. S., Moertel, C. L. & Baker, K. S., May 1 2009, In : Journal of Pediatrics. 154, 5, p. 766-768 3 p.

Research output: Contribution to journalArticle

31 Scopus citations
2008

Treatment of recurrent clear cell sarcoma of the kidney with brain metastasis

Radulescu, V. C., Gerrard, M., Moertel, C., Grundy, P. E., Mathias, L., Feusner, J., Diller, L. & Dome, J. S., Feb 1 2008, In : Pediatric Blood and Cancer. 50, 2, p. 246-249 4 p.

Research output: Contribution to journalArticle

21 Scopus citations
2007

Cerebral metastasis and other central nervous system complications of pleuropulmonary blastoma

Priest, J. R., Magnuson, J., Williams, G. M., Abromowitch, M., Byrd, R., Sprinz, P., Finkelstein, M., Moertel, C. L. & Hill, D. A., Sep 1 2007, In : Pediatric Blood and Cancer. 49, 3, p. 266-273 8 p.

Research output: Contribution to journalArticle

47 Scopus citations
2006

Type I pleuropulmonary blastoma: A report from the international pleuropulmonary blastoma registry

Priest, J. R., Hill, D. A., Williams, G. M., Moertel, C. L., Messinger, Y., Finkelstein, M. J. & Dehner, L. P., Sep 20 2006, In : Journal of Clinical Oncology. 24, 27, p. 4492-4498 7 p.

Research output: Contribution to journalArticle

81 Scopus citations

Uncommon Tumors of the Gastrointestinal Tract in Children

Moertel, C. L., Watterson, J. & Dehner, L. P., Jul 11 2006, Textbook of Uncommon Cancer, Third Edition. John Wiley & Sons, Ltd, p. 749-759 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2004

Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2

Widemann, B. C., Balis, F. M., Shalabi, A., Boron, M., O'Brien, M., Cole, D. E., Jayaprakash, N., Ivy, P., Castle, V., Muraszko, K., Moertel, C. L., Trueworthy, R., Hermann, R. C., Moussa, A., Hinton, S., Reaman, G., Poplack, D. & Adamson, P. C., Oct 20 2004, In : Journal of the National Cancer Institute. 96, 20, p. 1557-1559 3 p.

Research output: Contribution to journalArticle

43 Scopus citations
2003

Iron-deficiency anemia in bottle-fed toddlers

Vang, C. & Moertel, C. L., Dec 1 2003, Healing by Heart: Clinical and Ethical Case Stories of Hmong Families and Western Providers. Vanderbilt University Press, p. 144-148 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sleep in children with neoplasms of the central nervous system: case review of 14 children.

Rosen, G. M., Bendel, A. E., Neglia, J. P., Moertel, C. L. & Mahowald, M., Jul 1 2003, In : Pediatrics. 112, 1 Pt 1

Research output: Contribution to journalReview article

66 Scopus citations
2001

Acute polyosteal osteomyelitis in a patient with congenital ichthyosis and acute lymphoblastic leukemia

Tolar, J., Kravitz, G., Walker, K. & Moertel, C. L., Jan 1 2001, In : Pediatric Infectious Disease Journal. 20, 8, p. 813-814 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Eosinophil-associated inflammation and elaboration of eosinophil-derived proteins in 2 children with raccoon roundworm (Baylisascaris procyonis) encephalitis.

Moertel, C. L., Kazacos, K. R., Butterfield, J. H., Kita, H., Watterson, J. & Gleich, G. J., Nov 2001, In : Pediatrics. 108, 5, p. E93

Research output: Contribution to journalArticle

31 Scopus citations

Lymphomatoid granulomatosis after childhood acute lymphoblastic leukemia: report of effective therapy.

Moertel, C. L., Carlson-Green, B., Watterson, J. & Simonton, S. C., May 2001, In : Pediatrics. 107, 5

Research output: Contribution to journalArticle

14 Scopus citations
1998

Treatment of intermediate risk rhabdomyosarcoma and undifferentiated sarcoma with alternating cycles of vincristine/doxorubicin/cyclophosphamide and etoposide/ifosfamide

Arndt, C. A. S., Nascimento, A. G., Schroeder, G., Schomberg, P. J., Neglia, J. P., Sencer, S. F., Silberman, T. L., Moertel, C. L., Tillisch, J. K. & Miser, J. S., Jul 1 1998, In : European Journal of Cancer. 34, 8, p. 1224-1229 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Whole blood tissue factor procoagulant activity is elevated in patients with sickle cell disease

Key, N. S., Slungaard, A., Dandelet, L., Nelson, S. C., Moertel, C., Styles, L. A., Kuypers, F. A. & Bach, R. R., Jun 1 1998, In : Blood. 91, 11, p. 4216-4223 8 p.

Research output: Contribution to journalArticle

213 Scopus citations
1997

Acute idiopathic thrombocytopenic purpura - Management in childhood [3]

Buchanan, G. R., De Alarcon, P. A., Feig, S. A., Gilchrist, G. S., Lukens, J. N., Moertel, C. L., Cohen, A. R., Dickerman, J. D., Forman, E. N., Glafer, B. E. & Lusher, J. M., Feb 26 1997, In : Blood. 89, 4, p. 1464-1465 2 p.

Research output: Contribution to journalLetter

25 Scopus citations

One course versus two courses of antithymocyte globulin for the treatment of severe aplastic anemia in children

Matloub, Y. H., Smith, C., Bostrom, B., Koerper, M. A., O’Leary, M., Khuder, S., Smithson, W. A., Nickerson, H. J., Silberman, T., Hilden, J., Moertel, C. L., Month, S., Monteleone, P. & Ramsay, N. K. C., Jan 1 1997, In : American Journal of Pediatric Hematology/Oncology. 19, 2, p. 110-114 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Retinal toxicity associated with cisplatin and etoposide in pediatric patients

Hilliard, L. M., Berkow, R. L., Watterson, J., Ballard, E. A., Balzer, G. K. & Moertel, C. L., Apr 1 1997, In : Medical and Pediatric Oncology. 28, 4, p. 310-313 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

The use of implantable venous access devices (IVADs) in children with hemophilia

Perkins, J. L., Johnson, V. A., Osip, J. M., Christie, B. A., Nelson, S. C., Moertel, C. L. & Heisel, M. A., Jan 1 1997, In : American Journal of Pediatric Hematology/Oncology. 19, 4, p. 339-344 6 p.

Research output: Contribution to journalArticle

46 Scopus citations
1996

Lupus anticoagulant and protein S deficiency in children with postvaricella purpura fulminans or thrombosis

Manco-Johnson, M. J., Nuss, R., Key, N., Moertel, C., Jacobson, L., Meech, S., Weinberg, A. & Lefkowitz, J., Jan 1 1996, In : Journal of Pediatrics. 128, 3, p. 319-323 5 p.

Research output: Contribution to journalArticle

159 Scopus citations

Serologic evidence that factor IX inhibitor in the plasma of hemophilia B patients detects factor IX on normal red cells

Swanson, J. L., Moertel, C. L., Stroncek, D. F. & Key, N. S., May 1996, In : Transfusion. 36, 5, p. 467-469 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Stereotactic radiosurgery in pediatric patients

Weprin, B. E., Hall, W. A., Cho, K. H., Sperduto, P. W., Gerbi, B. J. & Moertel, C. L., Oct 1 1996, In : Pediatric Neurology. 15, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
1995

Follicular large cell lymphoma of the testis in a child

Moertel, C. L., Watterson, J., McCormick, S. R. & Simonton, S. C., Mar 1 1995, In : Cancer. 75, 5, p. 1182-1186 5 p.

Research output: Contribution to journalArticle

31 Scopus citations