20082022
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Research Output 2008 2019

2019

Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

Camell, C. D., Günther, P., Lee, A., Goldberg, E. L., Spadaro, O., Youm, Y. H., Bartke, A., Hubbard, G. B., Ikeno, Y., Ruddle, N. H., Schultze, J. & Dixit, V. D., Dec 3 2019, In : Cell Metabolism. 30, 6, p. 1024-1039.e6

Research output: Contribution to journalArticle

Inflammasomes
Homeostasis
B-Lymphocytes
Adipose Tissue
Lipolysis
2017
36 Citations (Scopus)

IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge

Spadaro, O., Camell, C. D., Bosurgi, L., Nguyen, K. Y., Youm, Y. H., Rothlin, C. V. & Dixit, V. D., Apr 11 2017, In : Cell reports. 19, 2, p. 225-234 10 p.

Research output: Contribution to journalArticle

Open Access
Macrophage Activation
Macrophages
Chemical activation
Knockout Mice
Insulin Resistance
73 Citations (Scopus)

Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing

Camell, C., Sander, J., Spadaro, O., Lee, A., Nguyen, K. Y., Wing, A., Goldberg, E. L., Youm, Y. H., Brown, C. W., Elsworth, J., Rodeheffer, M. S., Schultze, J. L. & Dixit, V. D., Oct 5 2017, In : Nature. 550, 7674, p. 119-123 5 p.

Research output: Contribution to journalArticle

Inflammasomes
Lipolysis
Catecholamines
Macrophages
Growth Differentiation Factor 3
2016
27 Citations (Scopus)

Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence

Spadaro, O., Goldberg, E. L., Camell, C. D., Youm, Y. H., Kopchick, J. J., Nguyen, K. Y., Bartke, A., Sun, L. Y. & Dixit, V. D., Feb 23 2016, In : Cell reports. 14, 7, p. 1571-1580 10 p.

Research output: Contribution to journalArticle

Open Access
Laron Syndrome
Inflammasomes
Somatotropin Receptors
Macrophages
Chemical activation
2015
20 Citations (Scopus)

Macrophage-specific de Novo synthesis of ceramide is dispensable for inflammasome-driven inflammation and insulin resistance in obesity

Camell, C. D., Nguyen, K. Y., Jurczak, M. J., Christian, B. E., Shulman, G. I., Shadel, G. S. & Dixit, V. D., Dec 4 2015, In : Journal of Biological Chemistry. 290, 49, p. 29402-29413 12 p.

Research output: Contribution to journalArticle

Open Access
Inflammasomes
Macrophages
Ceramides
Insulin Resistance
Obesity
19 Citations (Scopus)

Regulation of Nlrp3 inflammasome by dietary metabolites

Camell, C., Goldberg, E. & Dixit, V. D., Sep 1 2015, In : Seminars in Immunology. 27, 5, p. 334-342 9 p.

Research output: Contribution to journalReview article

Inflammasomes
Chronic Disease
Inflammation
Biosynthetic Pathways
Adiposity
2013
20 Citations (Scopus)

Dietary Oleic Acid Increases M2 Macrophages in the Mesenteric Adipose Tissue

Camell, C. & Smith, C. W., Sep 30 2013, In : PloS one. 8, 9, e75147.

Research output: Contribution to journalArticle

Open Access
Macrophages
Oleic Acid
adipose tissue
oleic acid
Adipose Tissue
2008
12 Citations (Scopus)

Selective expansion of memory CD4+ T cells by mitogenic human CD28 generates inflammatory cytokines and regulatory T cells

Singh, M., Basu, S., Camell, C., Couturier, J., Nudelman, R. J., Medina, M. A., Rodgers, J. R. & Lewis, D. E., Jun 1 2008, In : European Journal of Immunology. 38, 6, p. 1522-1532 11 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Cytokines
T-Lymphocytes
Eragrostis
Aptitude