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Research Output 2013 2020

2020
Drug Stability
Norfloxacin
Surface-Active Agents
Sodium Dodecyl Sulfate
Salts
ferulic acid
Crystallization
Powders
Emulsions
Pharmaceutical Preparations
2019
1 Citation (Scopus)

Cocrystal Engineering of Itraconazole with Suberic Acid via Rotary Evaporation and Spray Drying

Weng, J., Wong, S. N., Xu, X., Xuan, B., Wang, C., Chen, R., Sun, C., Lakerveld, R., Kwok, P. C. L. & Chow, S. F., May 1 2019, In : Crystal Growth and Design. 19, 5, p. 2736-2745 10 p.

Research output: Contribution to journalArticle

Spray drying
Itraconazole
drying
sprayers
Evaporation
2 Citations (Scopus)

Computational Techniques for Predicting Mechanical Properties of Organic Crystals: A Systematic Evaluation

Wang, C. & Sun, C. C., Apr 1 2019, In : Molecular Pharmaceutics. 16, 4, p. 1732-1741 10 p.

Research output: Contribution to journalArticle

Elasticity
Oxalic Acid
Powders
Open Access
Phase stability
linear equations
Crystallization
Hydrates
Linear equations
1 Citation (Scopus)

Developing Biologics Tablets: The Effects of Compression on the Structure and Stability of Bovine Serum Albumin and Lysozyme

Wei, Y., Wang, C., Jiang, B., Sun, C. C. & Middaugh, C. R., Mar 4 2019, In : Molecular Pharmaceutics. 16, 3, p. 1119-1131 13 p.

Research output: Contribution to journalArticle

Muramidase
Bovine Serum Albumin
Biological Products
Tablets
Humidity

Fast Determination of Phase Stability of Hydrates Using Intrinsic Dissolution Rate Measurements

Wen, H., Wang, C. & Sun, C. C., Oct 2 2019, In : Crystal Growth and Design. 19, 10, p. 5471-5476 6 p.

Research output: Contribution to journalArticle

Phase stability
Hydrates
hydrates
dissolving
Dissolution
1 Citation (Scopus)

Mechanism for the Reduced Dissolution of Ritonavir Tablets by Sodium Lauryl Sulfate

Guo, Y., Wang, C., Dun, J., Du, L., Hawley, M. & Sun, C., Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 516-524 9 p.

Research output: Contribution to journalArticle

Ritonavir
Sodium Dodecyl Sulfate
Tablets
Stomach
Salts

Molecular Interpretation of the Compaction Performance and Mechanical Properties of Caffeine Cocrystals: A Polymorphic Study

Singaraju, A. B., Bahl, D., Wang, C., Swenson, D. C., Sun, C. C. & Stevens, L. L., Jan 1 2019, (Accepted/In press) In : Molecular Pharmaceutics. 17, 1, p. 21-31 11 p.

Research output: Contribution to journalArticle

3-nitrobenzoic acid
Caffeine
Plastics
Powders
Light
2 Citations (Scopus)
Griseofulvin
Solvation
Dichloromethane
Crystallization
plastic properties

Reduced Punch Sticking Propensity of Acesulfame by Salt Formation: Role of Crystal Mechanical Property and Surface Chemistry

Paul, S., Wang, C., Wang, K. & Sun, C., Jun 3 2019, In : Molecular Pharmaceutics. 16, 6, p. 2700-2707 8 p.

Research output: Contribution to journalArticle

Surface Properties
Tablets
Salts
Particle Size
Pharmaceutical Preparations
6 Citations (Scopus)

Robust bulk preparation and characterization of sulfamethazine and saccharine salt and cocrystal polymorphs

Perumalla, S. R., Wang, C., Guo, Y., Shi, L. & Sun, C. C., Jan 1 2019, In : CrystEngComm. 21, 13, p. 2089-2096 8 p.

Research output: Contribution to journalArticle

Sulfamethazine
Polymorphism
Salts
melting
salts

Single-Crystal Plasticity Defies Bulk-Phase Mechanics in Isoniazid Cocrystals with Analogous Coformers

Yadav, J. P., Yadav, R. N., Sihota, P., Chen, H., Wang, C., Sun, C. C., Kumar, N., Bansal, A. & Jain, S., Aug 7 2019, In : Crystal Growth and Design. 19, 8, p. 4465-4475 11 p.

Research output: Contribution to journalArticle

Isoniazid
plastic properties
Plasticity
Mechanics
Single crystals
2 Citations (Scopus)

Spherical Cocrystallization - An Enabling Technology for the Development of High Dose Direct Compression Tablets of Poorly Soluble Drugs

Chen, H., Guo, Y., Wang, C., Dun, J. & Sun, C., Apr 3 2019, In : Crystal Growth and Design. 19, 4, p. 2503-2510 8 p.

Research output: Contribution to journalArticle

Griseofulvin
tablets
Tablets
Dissolution
drugs

Structural Features of Sulfamethizole and Its Cocrystals: Beauty within

Yuan, Y., Li, D., Wang, C., Chen, S., Kong, M., Deng, Z., Sun, C. C. & Zhang, H., Dec 4 2019, In : Crystal Growth and Design. 19, 12, p. 7185-7192 8 p.

Research output: Contribution to journalArticle

Sulfamethizole
Hydrogen bonds
Dissolution
Solubility
Crystal structure
2018
4 Citations (Scopus)

Anion Exchange Reaction for Preparing Acesulfame Solid Forms

Wang, C., Perumalla, S. R. & Sun, C. C., Aug 1 2018, In : Crystal Growth and Design. 18, 8, p. 4215-4219 5 p.

Research output: Contribution to journalArticle

Anions
Ion exchange
Negative ions
Salts
anions
15 Citations (Scopus)
Polymorphism
Plasticity
slip
topology
Visualization
3 Citations (Scopus)

Lack of dependence of mechanical properties of baicalein cocrystals on those of the constituent components

Liu, L., Wang, C., Dun, J., Chow, A. H. L. & Sun, C. C., Jan 1 2018, In : CrystEngComm. 20, 37, p. 5486-5489 4 p.

Research output: Contribution to journalArticle

Caffeine
caffeine
nicotinamide
plastic properties
Plasticity
10 Citations (Scopus)

Preparation, Characterization, and Formulation Development of Drug-Drug Protic Ionic Liquids of Diphenhydramine with Ibuprofen and Naproxen

Wang, C., Chopade, S. A., Guo, Y., Early, J. T., Tang, B., Wang, E., Hillmyer, M. A., Lodge, T. P. & Sun, C. C., Sep 4 2018, In : Molecular Pharmaceutics. 15, 9, p. 4190-4201 12 p.

Research output: Contribution to journalArticle

Diphenhydramine
Ionic Liquids
Drug Compounding
Naproxen
Ibuprofen
2017
10 Citations (Scopus)
Metformin
Tablets
Salts
Hardness
Solubility
7 Citations (Scopus)

Expedited Development of Diphenhydramine Orally Disintegrating Tablet through Integrated Crystal and Particle Engineering

Wang, C., Hu, S. & Sun, C., Oct 2 2017, In : Molecular Pharmaceutics. 14, 10, p. 3399-3408 10 p.

Research output: Contribution to journalArticle

Diphenhydramine
Tablets
Sweetening Agents
Pharmaceutical Preparations
Salts
22 Citations (Scopus)

Gastrointestinal stability of dihydromyricetin, myricetin, and myricitrin: an in vitro investigation

Xiang, D., Wang, C. G., Wang, W. Q., Shi, C. Y., Xiong, W., Wang, M. D. & Fang, J. G., Aug 18 2017, In : International Journal of Food Sciences and Nutrition. 68, 6, p. 704-711 8 p.

Research output: Contribution to journalArticle

myricetin
Flavonoids
flavonoids
Pancreatin
pancreatin
10 Citations (Scopus)

Relationships among Crystal Structures, Mechanical Properties, and Tableting Performance Probed Using Four Salts of Diphenhydramine

Wang, C., Paul, S., Wang, K., Hu, S. & Sun, C., Nov 1 2017, In : Crystal Growth and Design. 17, 11, p. 6030-6040 11 p.

Research output: Contribution to journalArticle

Diphenhydramine
Salts
Crystal structure
mechanical properties
salts
2016
27 Citations (Scopus)

Enhancing Bioavailability of Dihydromyricetin through Inhibiting Precipitation of Soluble Cocrystals by a Crystallization Inhibitor

Wang, C., Tong, Q., Hou, X., Hu, S., Fang, J. & Sun, C. C., Sep 7 2016, In : Crystal Growth and Design. 16, 9, p. 5030-5039 10 p.

Research output: Contribution to journalArticle

bioavailability
Crystallization
inhibitors
dissolving
Dissolution
13 Citations (Scopus)

Solid-state characterization of optically pure (+)Dihydromyricetin extracted from Ampelopsis grossedentata leaves

Wang, C., Xiong, W., Reddy Perumalla, S., Fang, J. & Calvin Sun, C., Sep 10 2016, In : International journal of pharmaceutics. 511, 1, p. 245-252 8 p.

Research output: Contribution to journalArticle

Ampelopsis
Pharyngitis
dihydromyricetin
Chinese Traditional Medicine
Fourier Transform Infrared Spectroscopy
30 Citations (Scopus)

Sweet Berberine

Wang, C., Perumalla, S. R., Lu, R., Fang, J. & Sun, C., Feb 3 2016, In : Crystal Growth and Design. 16, 2, p. 933-939 7 p.

Research output: Contribution to journalArticle

Berberine
Salts
salts
drugs
taste
2015
15 Citations (Scopus)

Preparation, characterization and in vivo studies of amorphous solid dispersion of berberine with hydrogenated phosphatidylcholine

Shi, C., Tong, Q., Fang, J., Wang, C., Wu, J. & Wang, W., Jul 1 2015, In : European Journal of Pharmaceutical Sciences. 74, p. 11-17 7 p.

Research output: Contribution to journalArticle

Berberine
Phosphatidylcholines
Biological Availability
Intestinal Absorption
Permeability
2013
1 Citation (Scopus)

Pharmaceutical powders flow properties characterization: methods and applications

Wang, C. G. & Fang, J. G., Apr 15 2013, In : Chinese Journal of New Drugs. 22, 7, p. 809-813 5 p.

Research output: Contribution to journalReview article

Powders
Pharmaceutical Preparations

Pharmaceutical powders tabletability: influencing factors and improvement strategies

Wang, C. G., Deng, L. & Shi, C. Y., Jun 8 2013, In : Chinese Pharmaceutical Journal. 48, 11, p. 845-849 5 p.

Research output: Contribution to journalReview article

Powders
Pharmaceutical Preparations